12-O-Tiglylphorbol-13-isobutyrate | CAS:92214-54-5

12-O-Tiglylphorbol-13-isobutyrate

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Product Name	12-O-Tiglylphorbol-13-isobutyrate
Price:	$490 / 5mg
CAS No.:	92214-54-5
Catalog No.:	CFN90368
Molecular Formula:	C₂₉H₄₀O₈
Molecular Weight:	516.62 g/mol
Purity:	>=98%
Type of Compound:	Diterpenoids
Physical Desc.:	White powder
Source:	The seeds of Euphorbia lathyris L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $540.5 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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12-O-Tiglylphorbol-13-isobutyrate Description

Source:	The seeds of Euphorbia lathyris L.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Journal of the American Oil Chemists Society,1984,61(7): 1220-5.

Short-chain phorbol ester constituents of croton oil[Reference: WebLink]

METHODS AND RESULTS:
Five phorbol diesters, three 4-deoxy-4α-phorbol diesters, two phorbol monoesters, and one 4-deoxy-4α-phorbol monoester were isolated from a commercial sample of croton oil and characterized spectroscopically. Their purification was achieved using combinations of droplet countercurrent chromatography, low-pressure column chromatography over phase-bonded silica gel, and preparative thin layer chromatography.
CONCLUSIONS:
All of these isolates were shown to possess short-chain ester functionalities, with 12-O-Tiglylphorbol-13-isobutyrate, 12-O-(2-methyl)butyrylphorbol-13-isobutyrate, 12-O-(2-methyl)butyrylphorbol-13-acetate, 12-O-tiglyl-4-deoxy-4α-phorbol-13-isobutyrate, 12-O-tiglyl-4-deoxy-4α-phorbol-13-acetate, 12-O-(2-methyl)butyryl-4-deoxy-4α-phorbol-13-acetate, phorbol-12-tiglate and 4-deoxy-4α-phorbol-13-acetate being new compounds.

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Anticancer Compound Library Cytotoxic Compound Library Antileukaemic Compound Library Diterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.9357 mL	9.6783 mL	19.3566 mL	38.7132 mL	48.3915 mL
5 mM	0.3871 mL	1.9357 mL	3.8713 mL	7.7426 mL	9.6783 mL
10 mM	0.1936 mL	0.9678 mL	1.9357 mL	3.8713 mL	4.8391 mL
50 mM	0.0387 mL	0.1936 mL	0.3871 mL	0.7743 mL	0.9678 mL
100 mM	0.0194 mL	0.0968 mL	0.1936 mL	0.3871 mL	0.4839 mL

CFN92861	Kansuiphorin C	133898-77-8	478.6	C₂₉H₃₄O₆
CFN92823	Phorbol	17673-25-5	364.4	C₂₀H₂₈O₆
CFN95773	Prostratin	60857-08-1	390.5	C₂₂H₃₀O₆
CFN96927	Phorbol 13-acetate	32752-29-7	406.47	C₂₂H₃₀O₇
CFN90368	12-O-Tiglylphorbol-13-isobutyrate	92214-54-5	516.62	C₂₉H₄₀O₈
CFN90923	Ingenol-5,20-acetonide	77573-43-4	388.5	C₂₃H₃₂O₅
CFN93015	Ingenol-5,20-acetonide-3-O-angelate	87980-68-5	470.60	C₂₈H₃₈O₆
CFN90922	Ingenol-3,4:5,20-diacetonide	77573-44-5	428.6	C₂₆H₃₆O₅
CFN90924	Ingenol 3-Angelate	75567-37-2	430.5	C₂₅H₃₄O₆
CFN93023	20-O-Acetylingenol-3-angelate	82425-35-2	472.57	C₂₇H₃₆O₇