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1H-Indole-3-carboxylic acid
1H-Indole-3-carboxylic acid
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 1H-Indole-3-carboxylic acid
Price: $30 / 20mg
CAS No.: 771-50-6
Catalog No.: CFN97256
Molecular Formula: C9H7NO2
Molecular Weight: 161.2 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The roots of Carpesium abrotanoides
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / $7.0 / In-stock
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Indole-3-carboxylic acid is a normal urinary indolic tryptophan metabolite which belongs to a class of organic compounds known as indolecarboxylic acids and derivatives.
Targets: 5-HT Receptor
1H-Indole-3-carboxylic acid Description
Source: The roots of Carpesium abrotanoides
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 6.2035 mL 31.0174 mL 62.0347 mL 124.0695 mL 155.0868 mL
5 mM 1.2407 mL 6.2035 mL 12.4069 mL 24.8139 mL 31.0174 mL
10 mM 0.6203 mL 3.1017 mL 6.2035 mL 12.4069 mL 15.5087 mL
50 mM 0.1241 mL 0.6203 mL 1.2407 mL 2.4814 mL 3.1017 mL
100 mM 0.062 mL 0.3102 mL 0.6203 mL 1.2407 mL 1.5509 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Bioorg Med Chem Lett. 2008 Jul 15;18(14):3844-7.
Synthesis and structure-activity relationship of 1H-indole-3-carboxylic acid pyridine-3-ylamides: a novel series of 5-HT2C receptor antagonists.[Pubmed: 18602261]
A novel series of 1H-Indole-3-carboxylic acid pyridine-3-ylamides were synthesized and identified to show high affinity and selectivity for 5-HT(2C) receptor. Among them, 1H-Indole-3-carboxylic acid[6-(2-chloro-pyridin-3-yloxy)-pyridin-3-yl]-amide (15k) exhibits the highest affinity (IC(50)=0.5 nM) with an excellent selectivity (>2000 times) over other serotonin (5-HT(1A), 5-HT(2A), and 5-HT(6)) and dopamine (D(2)-D(4)) receptors.
CFN961922-(1H-Indole-3-carboxamido)benzoic acid171817-95-1280.3C16H12N2O3
CFN91534Cephalandole B915315-44-5294.3C17H14N2O3
CFN96487Indole-3-glyoxylamide5548-10-7188.18C10H8N2O2
CFN97552Paniculidine A97399-93-4231.3 C14H17NO2
CFN97553Paniculidine B97399-94-5233.3 C14H19NO2
CFN97554Paniculidine C97399-95-6203.3 C13H17NO
CFN99899Indole-3-acrylic acid methyl ester19626-92-7201.2 C12H11NO2
CFN95263Indolelactic acid1821-52-9205.2C11H11NO3
CFN97559Methyl 3-carbazolecarboxylate97931-41-4225.2 C14H11NO2
CFN91466Mukonine23523-94-6255.3C15H13NO3
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