2,2-Dimethyl-6-phenylpyrano[3,4-b]pyran-8-one | CAS:1153624-36-2

2,2-Dimethyl-6-phenylpyrano[3,4-b]pyran-8-one

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Description:

2,2-Dimethyl-6-phenylpyrano[3,4-b]pyran-8-one is a natural product from the metabolites of Hypericum revolutum ssp.

In vitro:

Phytochemistry. 2009 Feb;70(3):403-6.

Dibenzofuran and pyranone metabolites from Hypericum revolutum ssp. revolutum and Hypericum choisianum.[Pubmed: 19200564 ]

METHODS AND RESULTS:
In a project to isolate and characterise anti-staphylococcal compounds from members of the genus Hypericum, a dibenzofuran and a pyranone were isolated from the dichloromethane and hexane extracts of Hypericum revolutum ssp. revolutum Vahl (Guttiferae) and Hypericum choisianum Wall. ex. N. Robson (Guttiferae), respectively. The structures of these compounds were elucidated by 1- and 2D-NMR spectroscopy and mass spectrometry as 3-hydroxy-1,4,7-trimethoxydibenzofuran (1) and 4-(3-O-3'')-3''-methylbutenyl-6-phenyl-pyran-2-one (2,2-Dimethyl-6-phenylpyrano[3,4-b]pyran-8-one,2). The metabolites were evaluated against a panel of multidrug-resistant strains of Staphylococcus aureus.
CONCLUSIONS:
Compound 1 exhibited a minimum inhibitory concentration (MIC) of 256 microg/ml, whereas compound 2 was inactive at a concentration of 512 microg/ml.

2,2-Dimethyl-6-phenylpyrano[3,4-b]pyran-8-one Description

Source:	The metabolites of Hypericum revolutum ssp.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	2,2-Dimethyl-6-phenylpyrano[3,4-b]pyran-8-one
Price:
CAS No.:	1153624-36-2
Catalog No.:	CFN96978
Molecular Formula:	C₁₆H₁₄O₃
Molecular Weight:	254.28 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Oil
Source:	The metabolites of Hypericum revolutum ssp.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Phenols Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.9327 mL	19.6634 mL	39.3267 mL	78.6535 mL	98.3168 mL
5 mM	0.7865 mL	3.9327 mL	7.8653 mL	15.7307 mL	19.6634 mL
10 mM	0.3933 mL	1.9663 mL	3.9327 mL	7.8653 mL	9.8317 mL
50 mM	0.0787 mL	0.3933 mL	0.7865 mL	1.5731 mL	1.9663 mL
100 mM	0.0393 mL	0.1966 mL	0.3933 mL	0.7865 mL	0.9832 mL

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