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3,4-seco-Olean-12-en-4-ol-3,28-dioic acid
3,4-seco-Olean-12-en-4-ol-3,28-dioic acid
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Product Name 3,4-seco-Olean-12-en-4-ol-3,28-dioic acid
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CAS No.: 182249-69-0
Catalog No.: CFN96849
Molecular Formula: C30H48O5
Molecular Weight: 488.70 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The roots of Ligularia intermedia.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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Description: 3,4-seco-Olean-12-en-4-ol-3,28-dioic acid is a natural product from Ligularia intermedia.
3,4-seco-Olean-12-en-4-ol-3,28-dioic acid Description
Source: The roots of Ligularia intermedia.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.0462 mL 10.2312 mL 20.4625 mL 40.9249 mL 51.1561 mL
5 mM 0.4092 mL 2.0462 mL 4.0925 mL 8.185 mL 10.2312 mL
10 mM 0.2046 mL 1.0231 mL 2.0462 mL 4.0925 mL 5.1156 mL
50 mM 0.0409 mL 0.2046 mL 0.4092 mL 0.8185 mL 1.0231 mL
100 mM 0.0205 mL 0.1023 mL 0.2046 mL 0.4092 mL 0.5116 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Planta Med. 1997 Dec;63(6):573-4.
A-seco-oleane-type triterpene acids from Ligularia intermedia.[Pubmed: 17252382 ]
From the roots of Ligularia intermedia, two new naturally occurring 3,4-seco-oleanolic triterpene acids were isolated. Their structures were elucidated as A-homo-3a-oxa-olean-12-en-3-one-28-oic acid and 3,4-seco-Olean-12-en-4-ol-3,28-dioic acid by spectroscopic methods and chemical transformations. In addition, six known compounds were also obtained from this plant.
CFN960433-O-p-Coumaroyloleanolic acid151334-06-4602.9C39H54O5
CFN960503-O-Caffeoyloleanolic acid97534-10-6618.9C39H54O6
CFN957103alpha-Acetyloxy-25-hydroxyolean-12-en-28-oic acid469895-08-7514.8C32H50O5
CFN921943-oxo-Olean-12-en-28-oic acid17990-42-0454.7C30H46O3
CFN918143-Oxo-olean-12-en-28-oic acid methyl ester1721-58-0468.7C31H48O3
CFN96451Virgatic acid14356-51-5470.70C30H46O4
CFN98812Echinocystic acid510-30-5472.7 C30H48O4
CFN990673alpha-Akebonoic acid104777-61-9440.7 C29H44O3
CFN97523Sebiferenic acid94390-09-7472.7 C30H48O4
CFN968493,4-seco-Olean-12-en-4-ol-3,28-dioic acid182249-69-0488.70C30H48O5
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