Aloeresin D | CAS:105317-67-7 | Manufacturer ChemFaces

Aloeresin D

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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $102.0 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Description:

Aloeresin D is a natural product from Aloe arborescens Mill.

Targets:

BACE | Beta Amyloid

In vitro:

Planta Med. 2008 Apr;74(5):540-5.

BACE1 (beta-secretase) inhibitory chromone glycosides from Aloe vera and Aloe nobilis.[Pubmed: 18543151]

METHODS AND RESULTS:
Four new chromone glycosides allo-Aloeresin D (2) , C-2'-decoumaroyl-aloeresin G (8), 2'-O-coumaroyl-(S)-aloesinol (9), 2'-O-[ P-methoxy-(E)-cinnamoyl]-(S)-aloesinol (10) and nine known chromone glycosides ( 1, 3 - 7, 11 - 13) were isolated from two Aloe spp. plants, A. vera and A. nobilis. Among them, 1 and 8 showed significant inhibitory activity against BACE1 (beta-secretase) with IC (50) values of 39.0 and 20.5 x 10 (-6) M, as well as inhibition of Abeta (1-42) production by 7.4 and 12.3 %, respectively, in B103 neuroblastoma cells at 30 ppm.
CONCLUSIONS:
The preliminary structure-activity relationships of ALOE chromone glucosides were also discussed.

Aloeresin D Description

Source:	The herbs of Aloe arborescens Mill.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Aloeresin D
Price:	$288 / 20mg
CAS No.:	105317-67-7
Catalog No.:	CFN90717
Molecular Formula:	C₂₉H₃₂O₁₁
Molecular Weight:	556.56 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Powder
Source:	The herbs of Aloe arborescens Mill.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Flavonoids Compound Library Beta Amyloid Inhibitor Library BACE Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.7968 mL	8.9838 mL	17.9675 mL	35.935 mL	44.9188 mL
5 mM	0.3594 mL	1.7968 mL	3.5935 mL	7.187 mL	8.9838 mL
10 mM	0.1797 mL	0.8984 mL	1.7968 mL	3.5935 mL	4.4919 mL
50 mM	0.0359 mL	0.1797 mL	0.3594 mL	0.7187 mL	0.8984 mL
100 mM	0.018 mL	0.0898 mL	0.1797 mL	0.3594 mL	0.4492 mL

CFN96467	Undulatoside A	58108-99-9	354.31	C₁₆H₁₈O₉
CFN92909	Drynachromoside A	1507388-29-5	500.45	C₂₂H₂₈O₁₃
CFN89273	Cypellocarpin C	294856-66-9	520.53	C₂₆H₃₂O₁₁
CFN89020	Eucamalduside A	1287220-29-4	520.53	C₂₆H₃₂O₁₁
CFN92910	Monnieriside A	1401807-73-5	370.31	C₁₆H₁₈O₁₀
CFN96860	Cnidimol A	103629-80-7	276.28	C₁₅H₁₆O₅
CFN90808	Eugenin	480-34-2	206.2	C₁₁H₁₀O₄
CFN96198	8-Methyleugenitol	41682-21-7	220.2	C₁₂H₁₂O₄
CFN97544	5,7-Dihydroxy-2-isopropylchromone	96552-59-9	220.2	C₁₂H₁₂O₄
CFN89218	8-Glucosyl-5,7-dihydroxy-2-(1-methylpropyl)chromone	188818-27-1	396.39	C₁₉H₂₄O₉