Structure Identification: |
Yao xue xue bao,2011, 46(7):818-821. | Chemical constituents from Salvia przewalskii Maxim.[Reference: WebLink] | The investigation on Salvia przewalskii Maxim was carried out to find the relationship of the constituents and their pharmacological activities. METHODS AND RESULTS: The isolation and purification were performed by various chromatographies such as silica gel,Sephadex LH-20,RP-C18 column chromatography,etc.Further investigation on the fraction of the 95% ethanol extract of Salvia przewalskii Maxim yielded przewalskin Y-1(1),anhydride of tanshinone-ⅡA(2),sugiol(3),
Epi-Cryptoacetalide(4),cryptoacetalide(5),arucadiol(6),1-dehydromiltirone(7),miltirone(8),cryptotanshinone(9),tanshinone ⅡA(10) and isotanshinone-Ⅰ(11).Their structures were elucidated by the spectral analysis such as NMR(Nuclear Magnetic Resonance) and MS(Mass Spectrometry).
CONCLUSIONS:
Compound 1 is a new compound.Compounds 4 and 5 are mirror isomers(1∶3).Compounds 4,5,6,8,11 were isolated from Salvia przewalskii Maxim for the first time. |
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