| Structure Identification: |
| Zhong Yao Cai. 2012 Oct;35(10):1610-4. | | Study on chemical composition of ethylacetate fraction from Polygonum amplexicaule var. sinense.[Pubmed: 23627126] | To study chemical composition of ethylacetate fraction from Polygonoum amplexicaule D. Don var. sinense Forb.
METHODS AND RESULTS:
TLC, Normal-phase silica gel column, reveres-phase silica gel column, Sephadex-LH, semi-preparative HPLC column were used to isolate chemical compositions of ethylacetate fraction from Polygonoum var. sinense. RESULTS: Eight compounds were identified as: 1. P-Hydroxybenzoic acid, 2. P-Hydroxybenzoic ethanol, 3. Diisobutyl phthalate, 4. Vanillin, 5. Isovanillic acid, 6.3,4,5-trihydroxy-benzoic acid-butyl ester, 7. 4-hydroxy-3-methoxycinnamic acid, 8. 7-hydroxy-6-methoxycoumarin.
CONCLUSIONS:
Except of Diisobutyl phthalate, the others are isolated for the first from this plant, moreover, Vanillin, Isovanillic acid and P-hydro -xyphenethyl alcohol are gained from genus for the first time. | | Zhong Yao Cai. 2013 Nov;36(11):1774-8. | | Chemical constituents from the roots of Ilex pubescens.[Pubmed: 24956816] |
METHODS AND RESULTS:
The 95% ethanol extract of the plant was separated by silica gel, Sephadex LH-20 and preparative HPLC chromatography. The structures were elucidated based on the physiochemical properties and spectroscopic analysis. Fifteen compounds were isolated and identified as oleuropein(1), oleoside dimethyl ester(2),8 (Z)-nuezhenide(3),3,4-dicaffeoylquinic acid methyl ester(4),3,4,5-tricaffeoylquinic acid methyl ester (5), Isovanillic acid(6), syringic acid(7), 3beta-acetyloleanolic acid (8), 3beta-acetylursolic acid(9), uvaol(10), asiatic acid(11), 2alpha-hydroxyursolic acid(12), oleanolic acid (13), ursolic acid (14), stigmasterol-3-O-beta-D-glucopyranoside (15).
CONCLUSIONS:
Compounds 2,3,8,9 are obtained from this genus for the first time,compounds 5-7,10-12 are isolated from this plant for the first time. |
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