Rheediaxanthone A | CAS:77181-97-6 | Manufacturer ChemFaces

Rheediaxanthone A

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Description:

Rheediaxanthone A is a natural product from Calophyllum inophyllum.

In vitro:

Pak J Pharm Sci. 2015 Mar;28(2):425-9.

Antiproliferative xanthone derivatives from Calophyllum inophyllum and Calophyllum soulattri.[Pubmed: 25730799]

METHODS AND RESULTS:
Structure-activity relationships of eleven xanthones were comparatively predicted for four cancer cell lines after the compounds were subjected to antiproliferative assay against B-lymphocyte cells (Raji), colon carcinoma cells (LS174T), human neuroblastoma cells (IMR-32) and skin carcinoma cells (SK-MEL-28). The eleven chemical constituents were obtained naturally from the stem bark of Calophyllum inophyllum and Calophyllum soulattri. Inophinnin (1) and inophinone (2) were isolated from Calophyllum inophyllum while soulattrin (3) and phylattrin (4) were found from Calophyllum soulattri. The other xanthones were from both Calophyllum sp. and they are pyranojacareubin (5), Rheediaxanthone A (6), macluraxanthone (7), 4-hydroxyxanthone (8), caloxanthone C (9), brasixanthone B (10) and trapezifolixanthone (11).
CONCLUSIONS:
Compound 3 was found to be the most cytotoxic towards all the cancer cell lines with an IC50 value of 1.25μg/mL while the simplest xanthone, compound 8 was inactive.

Rheediaxanthone A Description

Source:	The stem barks of Calophyllum inophyllum.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Rheediaxanthone A
Price:
CAS No.:	77181-97-6
Catalog No.:	CFN89118
Molecular Formula:	C₂₃H₂₀O₆
Molecular Weight:	392.40 g/mol
Purity:	>=98%
Type of Compound:	Xanthones
Physical Desc.:	Powder
Source:	The stem barks of Calophyllum inophyllum.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Xanthones Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.5484 mL	12.7421 mL	25.4842 mL	50.9684 mL	63.7105 mL
5 mM	0.5097 mL	2.5484 mL	5.0968 mL	10.1937 mL	12.7421 mL
10 mM	0.2548 mL	1.2742 mL	2.5484 mL	5.0968 mL	6.371 mL
50 mM	0.051 mL	0.2548 mL	0.5097 mL	1.0194 mL	1.2742 mL
100 mM	0.0255 mL	0.1274 mL	0.2548 mL	0.5097 mL	0.6371 mL

CFN95152	New Compound 1	N/A	296.3	C₁₈H₁₆O₄
CFN91524	Garcixanthones B	2522597-99-3	380.4	C₂₃H₂₄O₅
CFN98427	8-Deoxygartanin	33390-41-9	380.4	C₂₃H₂₄O₅
CFN98428	Gartanin	33390-42-0	396.4	C₂₃H₂₄O₆
CFN92942	Xanthone V1a	103450-96-0	396.43	C₂₃H₂₄O₆
CFN89085	Pancixanthone A	174232-30-5	312.32	C₁₈H₁₆O₅
CFN89134	Isocudraniaxanthone A	197447-26-0	328.32	C₁₈H₁₆O₆
CFN96577	Isocudraniaxanthone B	199851-52-0	342.35	C₁₉H₁₈O₆
CFN97410	Cudraxanthone B	84955-05-5	394.4	C₂₃H₂₂O₆
CFN89371	Cudratricusxanthone A	740810-42-8	396.43	C₂₃H₂₄O₆