Structure Identification: |
Yakugaku Zasshi. 1990 Nov;110(11):834-8. | Studies on pharmacologically active principles from Indonesian crude drugs. III. Toxic components from Brucea javanica (L.) Merr.[Pubmed: 2082013] | METHODS AND RESULTS:
During our screening of pharmacologically active principles from Indonesian medicinal plants by a hypothermic effect the methanol-extract of Brucea javanica (L.) Merr. has been found to exhibit a lethal toxicity to mice.
CONCLUSIONS:
The toxic components were isolated and identified with bruceoside A and B and Yadanzioside F. Correction of 13C-nuclear magnetic resonance assignment was also mentioned. | Chemical & pharmaceutical bulletin, 1984, 32(11), 4702-5. | New quassinoid glycosides, yadanziosides A-H, from Brucea javanica.[Reference: WebLink] | Eight new antileukemic quassinoid glycosides, yadanzioside A, yadanzioside B, yadanzioside C, yadanzioside D, yadanzioside E, Yadanzioside F, yadanzioside G, and yadanzioside H(1-8) were isolated from seeds of Brucea javanica and their structures were determined by chemical transformation and spectral analysis. |
|