|A unique collection of 60 Toxicity natural compounds for screening|
|Catalog No:||Bb201|| Toxicity Compound Library
|Size:||1mg/well * 60 Compounds|
2mg/well * 60 Compounds
1. The kinetics of Littorine biosynthesis were in agreement with the role of this compound as a direct precursor of hyoscyamine biosynthesis.
1. 2,4-Dihydroxyphenylacetic acid is a functional moiety in the toxin molecule and the biological action of spider toxin is explained by direct interaction with an Fe-S center which is known to play an important role for the glutamate binding.
1. Spathulenol has immunomodulatory effect.
2. Spathulenol shows the capacity to inhibit proliferation in the lymphocytes and to induce apoptosis in these cells possibly through a caspase-3 independent pathway.
3. Spathulenol presents moderate or low cytotoxicity with IC50 higher than 6uM, it is a good candidate to be used in combination chemotherapy of MDR cancer and therefore is worthy for further in vivo studies.
1. High levels of N-acetyl norloline and peramine may be of particular importance for developing 'friendly' endophyte-enhanced turf and pasture grasses that resist challenging lepidopteran pests.
2. N-acetyl norloline, which is produced by the Max P endophyte, may be responsible for a new form of toxicity called equine fescue oedema in horses.
1. Anacrotine produces much more severe lung damage than most other pyrrolizidine alkaloids.