Bioactive Products
| A unique collection of 60 Toxicity natural compounds for screening | ||
| Catalog No: | Bb201 | Toxicity Compound Library Screening Details |
| Size: | 1mg/well * 60 Compounds 2mg/well * 60 Compounds | |
| Cat. No. | Information |
| CFN98560 | Atractyloside A Atractyloside is a toxic compound from wedelia glauca. It acts as inhibitor of oxidative phosphorylation by a specific interference with energy-transfer reactions, the effect is due to inhibition of the ADP utilizing process in the coupling system. Atractyloside, has been proposed for the antibiotic oligomycin, is an inhibitor of the energy-transfer reactions in animal mitochondria; it inhibits the phosphate uptake and the respiratory stimulation induced by P1-acceptor, but it does not interfere with the so-called resting respiration. |
| CFN98561 | Atractyloside potassium salt Atractyloside potassium salt inhibits oxidative phosphorylation by blocking the transfer of adenosine nucleotides through the mitochondrial membrane. |
| CFN98731 | Artemetin Artemetin has anti-inflammatory, antioxidant and antiapoptotic activities, it protects endothelial function through the activation of ERK1/2 and Akt. Intravenous injection of Artemetin (0.75 mg/kg) significantly reduces the hypertensive response to angiotensin I while increases the average length of bradykinin-induced hypotension. |
| CFN98743 | Isosakuranetin Isosakuranetin is a plant exudate with known cytotoxic and fungicide properties, it may act on wheat root segments as an inhibitor of K+ permeation. Isosakuranetin is a TRPM3 blocker, significantly reduces the sensitivity of mice to noxious heat and PregS-induced chemical pain; it induced- inhibition of ERK1/2 and PI3K/AKT signaling pathways activate MITF and subsequent expression of Tyr, TRP1, and TRP2. |
| CFN00088 | Pahutoxin Pahutoxin is a natural fish-killing (ichthyotoxic) agent derived from the defensive secretions of trunkfish. It is also a haemolytic agent. |
