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Natural Products
Catalog No. Information
CFN90367 12-O-tetradecanoylphorbol-13-acetate

12-O-tetradecanoylphorbol-13-acetate has skin tumor-promoting potential, it induces endogenous FBXO10 mRNA and FBXO10 protein in Jurkat cells, a human T cell line. It provokes cell motility through regulating the expression and function of S100A14 in a KLF4-dependent manner.
CFN90368 12-O-Tiglylphorbol-13-isobutyrate

12-O-Tetradecanoylphorbol-13-acetate has cytotoxic against in vitro P-388 lymphocytic leukemia and KB nasopharyngeal carcinoma cell.
CFN98801 13(18)-Oleanen-3-ol

Standard reference
CFN98023 13(18)-Oleanen-3-one

δ-Amyrone(13(18)-Oleanen-3-one), a specific inhibitor of cyclooxygenase-2, possesses anti-inflammatory effects, which may be relevant to the regulation of COX-2; it exerts its protective effect on experimental gastric ulcer by inhibiting NF-κB signaling pathways, which subsequently reduces overproduction of the inducible enzymes iNOS and suppresses the release of the inflammatory factors TNF-α, IL-6 and NO. δ-Amyrone has protective activity on LPS-induced endotoxic shock, which is attributed to reducing NO production and mediating the pro-inflammatory cytokines, inhibited NF-κB expression.
CFN95307 13(S)-Hydroxyoctadeca-9(Z),11(E)-dienoic acid (13-HODE)

Anti-inflammatory.
13-HODE down-regulates the thrombogenecity of the injured vessel wall surface.
13-HODE prevents cell adhesion to endothelial cells and can inhibit cancer metastasis.
CFN92648 13-Hydroxygermacrone

13-Hydroxygermacrone inhibits UVB-induced upregulation of the mRNA and protein expression levels of MMP-1, MMP-2, and MMP-3 in human keratinocytes (HaCaT). 13-Hydroxygermacrone shows a protective effect against D-GalN/tumor necrosis factor-alpha-induced liver injury in mice at a dose of 50 mg/kg p.o.
CFN92232 13-Hydroxylupanine

13-Hydroxylupanine is a natural product from Cytisus scoparius.
CFN92395 13-Hydroxyoxyberberine

Reference standards.
CFN97822 14-Deoxy-11,12-didehydroandrographiside

Standard reference
CFN98666 14-Deoxy-11,12-didehydroandrographolide

14-Deoxy-11,12-didehydroandrographolide has hypotensive, anti-inflammatory, anti-asthma, and anti-cancer actions, it causes negative chronotropic action and antagonised isoproterenol-induced positive chronotropic actions in a non-competitive and dose-dependent manner. 14-Deoxy-11,12-didehydroandrographolide can effectively ameliorate astrocytic pro-inflammatory reactions and prevent PC12 cell death with different efficacies, it may be candidates for treatment of spinal-cord injury and neurodegeneration.