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    Natural Products
    Catalog No. Information
    CFN92157 8-Oxyberberine

    CFN92346 8-Prenylkaempferol

    1. 8-Prenylkaempferol is an effective agent for attenuating pro-inflammatory NO induction.
    2. 8-Prenylkaempferol induces differentiation/maturation of MC3T3-E1 osteoblasts by BMP-2/p38/Runx2 pathways , might be a promising agent for inducing osteogenesis.
    3. 8-Prenylkaempferol might be an anti-inflammatory agent for suppressing influenza A virus-induced RANTES production acts by blocking PI3K-mediated transcriptional activation of NF-κB and IRF-3 and in part by interfering with IκB degradation which subsequently decreases NF-κB translocation.
    CFN92016 8-Prenylnaringenin

    1. 8-Prenylnaringenin is a phytoestrogen with the highest estrogenic activity.
    2. 8-Prenylnaringenin and 6-prenylnaringenin shows slight activity in this assay but significant activity by immunostaining.
    3. 8-Prenylnaringenin at all assayed doses (0.001-20 µM) presumably improves mitochondrial function, whereas a high dose of XN (5 µM) worsens the functionality of this organelle.
    4. 8-Prenylnaringenin has more potent effects on promoting osteoblastic bone formation and inhibiting osteoclastic bone resorption by ERα instead of ERβ than the two classic phytoestrogens: genistein and daidzein.
    CFN92299 8-Shogaol

    1. 8-Shogaol can induce apoptosis in a time- and concentration-dependent manner by reactive oxygen species production and depletion of glutathione in HL-60 cells.
    CFN92011 9-Methoxycanthin-6-one

    1. 9-Methoxycanthin-6-one has anti-tumour activity, exhibits cytotoxic activity towards KB, LU-1, LNCaP, HL-60 cancer cells and other human cancer cell lines with IC50 values around 1-4 μg/mL.
    CFN90587 Abietic acid

    1. Abietic acid, a naturally occurring compound, can be used not only for anti-inflammation but also for regulating lipid metabolism and atherosclerosis.
    2. Abietic acid acts as a PPARα/γ dual activator to inhibit UVB-induced MMP-1 expression and age-related inflammation by suppressing NF-κB and the MAPK/AP-1 pathway and can be a useful agent for improving skin photoageing.
    CFN90168 Absinthiin

    1. Absinthin is a natural bitter flavoring constituent.
    CFN98744 Acacetin

    1. Acacetin has anti-peroxidative and anti-inflammatory effects, it can suppress LPS-induced up-expression of iNOS and COX-2 in murine macrophages and TPA-induced tumor promotion in mice.
    2. Acacetin is an atrium-selective agent that prolongs the atrial effective refractory period without prolonging the corrected QT interval and effectively prevents atrial fibrillation (AF) in anesthetized dogs after intraduodenal administration.
    3. Acacetin attenuates neuroinflammation via regulation the response to LPS stimuli in vitro and in vivo, it may act as a potential therapeutic agent for brain diseases involving neuroinflammation.
    4. Dietary acacetin can reduce airway hyperresponsiveness and eosinophil infiltration by modulating eotaxin-1 and th2 cytokines in a mouse model of asthma, suggests that dietary may improve symptoms in -sensitized.
    5. Acacetin has spasmolytic and antinociceptive activities.
    6. Acacetin has anti-cancer and antitumor activities, such as prostate cancer, melanoma angiogenesis tumor , via Akt/NF-κB,Stat signaling pathway.
    CFN97220 Acanthoside B

    1.Acanthoside has inhibitory effects on the allergic inflammation.
    CFN90523 Acetyl shikonin

    1. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC50 of over 20 microM, exhibits the antiangiogenic and antitumorigenic effects by suppressing proliferation and angiogenic factors.
    2. Acetylshikonin inhibits the generation of NADPH oxidase complex in the activation of respiratory burst of PMNs, but does not directly inhibit the activity of NADPH oxidase already generated.
    3. Certain shikonin derivatives(such as Acetyl shikonin) act as modulators of the Nur77-mediated apoptotic pathway and identify a new shikonin-based lead that targets Nur77 for apoptosis induction.
    4. Acetylshikonin, shikonin, and alkannin have accelerative effect on the proliferation of granulation tissue in rats.
    5. Acetylshikonin has inhibitory effect on the edematous response is due neither to the release of steroid hormones from the adrenal gland nor to the glucocorticoid activity, but probably partly to the suppression of mast cell degranulation and partly to protection of the vasculature from mediator challenge.
    6. Acetylshikonin induces apoptosis of hepatitis B virus X protein-expressing human hepatocellular carcinoma cells via endoplasmic reticulum stress.