Natural Products
| Catalog No. | Information |
| CFN91641 | (+)-Neodihydrocarveol (+)-Neodihydrocarveol, the active ingredient in the essential oil of calamintha officinalis Moench, has antifungal and antibacterial activity against Gram-positive bacteria. (+)-Neodihydrocarveol has enhances hypnosis and also prevents convulsions. |
| CFN91640 | Cepharanoline Cepharanoline has significant antiplasmodial activity and Proliferative activity of mouse skin cultured hair cells. |
| CFN91639 | Populninic acid |
| CFN91638 | Ingenol 3,20-dibenzoate Ingenol 3,20-dibenzoate is a potent, isoform-selective agonist of protein kinase C (PKC). Ingenol 3,20-dibenzoate induces selective translocation of nPKC-δ, -ε, and -θ and PKC-μ from the cytosolic fraction to the particulate fraction and induces morphologically typical apoptosis through de novo synthesis of macromolecules. Ingenol 3,20-dibenzoate increases the IFN-γ production and degranulation by NK cells, especially when NK cells are stimulated by NSCLC cells. |
| CFN91637 | Tauroursodeoxycholic acid sodium salt Tauroursodeoxycholate Sodium is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis. Tauroursodeoxycholic acid sodium salt significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholic acid sodium salt also inhibits ERK. |
| CFN91636 | (+)-beta-Cedrene β-cedrene are bioactive sesquiterpenes found in cedar essential oil and exert antiseptic, anti-inflammatory, antispasmodic, tonic, astringent, diuretic, sedative, insecticidal, and antifungal activities. β-Cedrene is a potent and competitive inhibitor of CYP2B6-mediated bupropion hydroxylase, and β-cedrene moderately blocks CYP3A4. |
| CFN91635 | (-)-alpha-Cedrene (-)-Cedrene (α-cedrene) is a sesquiterpene constituent of cedarwood oils, with anti-leukemic, antimicrobial and anti-obesity activities |
| CFN91634 | 5-alpha-Cholestane 5α-Cholestane belongs to the class of organic compounds known as cholestane steroids. |
| CFN91633 | 12-alpha-Hydroxyrotenone Rotenolone(12-alpha-Hydroxyrotenone) is the main metabolite of rotenone and has high insecticidal and fishicidal activities. |
| CFN91632 | D-Sorbose D-Sorbitose has the anti-obesity , anti-hyperglycaemic activities and the effect of enhancing lipid metabolism. D-sorbose have an inhibitory effect on disaccharidase activity. |
| CFN91631 | D-Iditol D-Iditol may have potential antitumour activity. |
| CFN91630 | Xylobiose Xylobiose exhibits anti-diabetic, hypolipogenic, and anti-inflammatory effects.Xylobiose has therapeutic potential for the treatment of obesity, including inhibition of fat deposition and obesity-related metabolic disorders. |
| CFN91629 | L-(+)-Ergothioneine Ergothioneine is synthesized by certain bacteria and fungi. It is generally considered an antioxidant, but also has anti-inflammatory, cyto-protective, liver-protecting properties. |
| CFN91628 | Dihydrokaempferol Dihydrokaempferol has antioxidant, anti-inflammatory, improving pancreatic damage and hepatoprotective effects, and can effectively promote cell apoptosis. |
| CFN91627 | Azadirachtin B Azadirachtin B is an limonoid isolated from seed kernels of Azadirachta indica and it is active against the Epstein-Barr virus early antigen (EBV-EA). Azadirachtin B increases alkaline phosphatase (ALP) activity and stimulates osteoblast differentiation. Azadirachtin B has insecticidal, nematocidal, anticancer, anti-inflammatory, antiviral and osteogenic properties. |
| CFN91626 | Hyocholic acid Hyocholic acid(HCA) upregulates GLP-1 production and secretion in enteroendocrine cells and improves glucose homeostasis. Hyocholic acid has the effect of preventing and dissolving gallstones. |
| CFN91625 | Oleuropein aglycone Oleuropein aglycone has anti-Alzheimer's disease, anti-breast cancer, anti-inflammatory, anti-hyperglycemic, antioxidant and lipid-lowering properties. |
| CFN91624 | Amorphigenin Amorphigenin in Amorpha fruticosa seeds is a carotenoid compound with antiproliferative and anticancer effects on a variety of cell types. Amorphigenin inhibits enzyme activity by binding to free enzyme and enzyme-substrate complexes, thereby reducing mitochondrial complex I activity. Amorphigenin significantly inhibits proliferation and induces apoptosis in A549/DDP cells. Amorphigenin inhibits RANKL-induced differentiation of osteoclasts from bone marrow macrophages in a dose-dependent manner without cytotoxicity. |
| CFN91623 | Aloenin B Aloenin B has neuroprotective activity against glutamate-induced neuronal death in HT22 cells. |
| CFN91622 | Piscidic acid Piscidic acid acts as an inhibitor of cholesterol permeation through Caco-2 cell monolayers and as an inhibitor of 3-hydroxy-3-methylglutaryl-CoA reductase. Piscidic acid have antioxidant and antimicrobial properties. |
| CFN91621 | Elemic acid |
| CFN91620 | Ishophloroglucin A Ishophloroglucin A(IPA) inhibits tyrosinase activity and melanogenesis induced by α-MSH in vivo and in vitro. IPA has high α-glucosidase inhibitory activity. IPA improved glucose homeostasis in HFD-induced diabetes via GLUT4 translation. IPA can ameliorate methylglyoxal-induced nephrotoxicity. |
| CFN91619 | Cannabidiol hydroxyquinone Cannabidiol hydroxyquinone(HU-331) might be an active metabolite of cannabidiol potentially contributing to the induction of apoptosis. HU-331 inhibits the ATPase activity of topoisomerase IIα using a noncompetitive mechanism. |
| CFN91618 | Epipodophyllotoxin (-)-Epipodophyllotoxin (2) is an antiproliferative agent against cancer cells isolated from American mayapple Podophyllum peltatum, with GI50s of 0.36 and 0.24 μM in HeLa cells and MCF-7 cells, respectively. (-)-Epipodophyllotoxin can inhibit mitotic spindle assembly in vitro. |
| CFN91617 | 1,1,1,1-Kestohexaose 1,1,1,1-Kestohexaose is a fructan oligomer isolated from Poa ampla |
| CFN91616 | 1-Triacontanol 1-Triacontanol is a naturally occurring plant growth regulator. 1-Triacontanol is a saturated long-chain alcohol that has growth-promoting activities on a number of plants. 1-Triacontanol reduces reactive oxidative damage. |
| CFN91615 | Monascin Monascin is a kind of azaphilonoid pigments extracted from Monascus pilosus-fermented rice (red-mold rice),exhibits anti-tumor-initiating activity and anti-inflammatory activity. Monascin inhibits the activation of NOR 1 (an NO donor).Monascin is a dual agonist of PPARγ and Nrf2. |
| CFN91614 | Epiprocurcumenol Epiprocurcumenol is a sesquiterpene isolated from Curcumae Rhizoma (CR). Epiprocurcumenol can effectively inhibit the expression of MAPK and PI3K-Akt signaling pathway-related proteins and decrease the protein expression levels of ERK, JNK, MAPK, PI3K, AKT and CCR5, thereby inhibiting platelet aggregation. |
| CFN91613 | Pumiloside Pumiloside could promote HUVEC cell proliferation, and pumiloside could up-regulate VEGF and p-ERK in HUVEC. |
| CFN91612 | Miroestrol Miroestrol is a highly active phytoestrogen. Miroestrol can produce mammogenic effect. Miroestrol exhibits bone loss prevention and neuroprotective in ovariectomized mice. Miroestrol also can reduce cancer risk. |
| CFN91611 | Cannabichromenic acid Cannabichromenic acid is a new antibiotic active against gram-positive bacteria, including MRSA. |
| CFN91610 | Cannabigerovarinic acid Cannabigerovarinic acid(CBGVA） may contribute to the effects of cannabis-based products in childhood epilepsy. |
| CFN91609 | Cannabichromevarinic acid Cannabichromevarinic acid has anticonvulsant properties |
| CFN91608 | Phlorigidoside C Phlorigidoside C possessed significant anti-rheumatoid arthritis (RA) activities on adjuvant-induced arthritis, which might be ascribed to the regulation of inflammatory cytokines IL-1β, TNF-α, IL-6, IFN-γ IL-17 and IL-10, as well as inhibition of OPG/RANKL/NF-κB signaling pathways. Phlorigidoside C, a natural iridoid glucoside, possesses anti-rheumatoid arthritis effect. |
| CFN91607 | 8-Dehydroxy shanzhiside 8-Dehydroxy shanzhiside have hemostasis and alleviating pain effects. |
| CFN91606 | Phloyoside II Phloyoside II have hemostasis and alleviating pain effects. |
| CFN91605 | Lactucin Lactucin exerting anti-malaria and anti-hyperalgesia, anti-adipogenesis and anti-inflammatory effects. Lactucin is an anti-inflammatory agent. Lactucin induces cancer cell apoptosis. Lactucin also shows analgesic, anticancer and antimalarial activities. |
| CFN91604 | (S)-(-)-Pulegone (S)-(-)-Pulegone is a monoterpenoid with anti-inflammatory and anti-hyperalgesic effects |
| CFN91603 | Eckol Eckol have anti-inflammatory,anti-tumor and cytoprotective effects. Eckol inhibits ultraviolet B-induced cell damage by a decrease in oxidative stress in human keratinocytes. Eckol shows effective protective activity against TNF-α/IFN-γ-induced skin inflammation. Eckol is a potent hMAO-A (Mixed) and hMAO-B (non-competitive) inhibitor with IC50s of 7.20 and 83.44 μM, respectively. Eckol shows stimulatory effects in maize and can be used as a plant biostimulant. Eckol also shows antiallergic and antiviral effects. |
| CFN91602 | Ankaflavin Ankaflavin, isolated from Monascus-Fermented red rice, is a PPARγ agonist with anti-inlfammatory activity. Ankaflavin exhibits selective cytotoxic effect and induces cell death on cancer cells. Ankaflavin has anti-inflammatory, anti-cancer, antiatherosclerotic, and hypolipidemic effects. |
| CFN91601 | (R)-(-)-alpha-Phellandrene (R)-(-)-alpha-Phellandrene has antibacterial and anticandidal activity.α-phellandrene is an orally active cyclic monoterpene that attenuates inflammatory response, and induces DNA damage |
| CFN91600 | Euphorbol Euphorbadienol is a triterpenic compound isolated from the latex of Euphorbia resinifera. The derivatives of Euphorbadienol can be used as elicitors of disease resistance, and has antileishmanial and antitrypanosomal activity. |
| CFN91599 | Apigenin 7-diglucuronide Apigenin-7-diglucuronide is a flavonoid glycoside that exists in an assortment of medicinal plants with anti-inflammatory or ant-oxidant activities. It protects retinas against bright light-induced photoreceptor degeneration through the inhibition of retinal oxidative stress and inflammation. |
| CFN91598 | L-Sulforaphane L-Sulforaphane possesses anticarcinogenic, antioxidant and anti-inflammatory effects. It's a potent inducer of the Keap1/Nrf2/ARE pathway, and it's also a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer. |
| CFN91597 | Bixin Bixin (BX), isolated from the seeds of Bixa orellana, is a carotenoid, possessing anti-inflammatory, anti-tumor and anti-oxidant activities. Bixin treatment ameliorated cardiac dysfunction through inhibiting fibrosis, inflammation and reactive oxygen species (ROS) generation. Bixin functions as a potent antagonist of PI3K/Akt signaling to protect against allergic asthma. |
| CFN91596 | Soyasaponin III Soyasaponin III, a monodesmodic oleanane triterpenoid, is one of the main potentially bioactive saponins found in soy (Glycine max) and related products. Soyasaponin III can induce apoptosis in Hep-G2 cells. Effects on immunohemolysis: Soyasaponin III plays an active role in anticomplementary activity in vitro |
| CFN91595 | Thapsigargin Thapsigargin is a potent, non-competitive inhibitor of the sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) with IC50 of 0.353 nM or 0.448 nM for the carbachol-evoked [Ca2+]i-transients with or without a KCl-prestimulation. Thapsigargin induces cell apoptosis. Thapsigargin efficiently inhibits coronavirus (HCoV-229E, MERS-CoV, SARS-CoV-2) replication in different cell types. |
| CFN91594 | Cyperenone Cyperotundone is a sesquiterpene isolated from Nagarmotha (Cyperus rotundus). Cyperotundone is an active constituent in Chuanxiong Rhizoma and Cyperi Rhizoma (CRCR) for treating migraine. In vitro studies demonstrated that Alpinia officinarum-Cyperus rotundus (HP G-X) and the corresponding single herbs significantly reduced IL-6, TNF-α, and COX-2. In vivo investigations indicated that HP G-X can protect the gastric mucosa of mice from ethanol-induced damage by inhibiting the inflammatory reaction and providing analgesia. It can also inhibit the expression of NF-κBp65, COX-2, and TRPV1 protein, reduce the concentrations of IL-6 and TNF-α, and relieve heat-induced pain. |
| CFN91593 | Neolinustatin Neolinustatin is toxic to aerobic organisms as a respiratory inhibitor and to enzymes containing heavy metals. Neolinustatin not only perform protective functions against herbivores but are general plant growth regulators, especially since changes in their level have been shown to be strongly correlated with significant stages of plant development. |
| CFN91592 | Dieckol Dieckol has been exhibited a broad spectrum of therapeutic functions including anti-bacterial, anti-cancer, anti-oxidant, anti-aging, anti-diabetic, neuroprotective, and other medicinal applications. Dieckol plays an important role in apoptosis induction via inhibiting the PI3K, AKT, mTOR and FAK signaling molecules. Dieckol remarkably inhibited the lipid accumulation in high fat diet induced animal models,decreased the size of LDs and modulated the contribution of LDs to less toxic ones by decreasing PLIN2 expression and thus attenuated muscle atrophy and strength, which were induced by HF. |
