Natural Products
Catalog No. | Information |
CFN91591 | Halleridone halleridone activated Nrf2-mediated HO-1 expression and inhibited Aβ1-42-overexpressed microglial BV-2 cell activation |
CFN91590 | Rottlerin Rottlerin is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM). Rottlerin causes apoptosis via caspase 3 activation. Rottlerin acts as a direct mitochondrial uncoupler, and stimulates autophagy by targeting a signaling cascade upstream of mTORC1. Rottlerin inhibits HIV-1 integration and Rabies virus (RABV) infection |
CFN91589 | Crosstide Crosstide is a peptide analog of glycogen synthase kinase α/β fusion protein sequence which is a substrate for Akt. |
CFN91588 | QS-21 QS-21, an immunostimulatory saponin, could be used as a potent vaccine adjuvant. QS-21 stimulates Th2 humoral and Th1 cell-mediated immune responses through action on antigen presenting cells (APCs) and T cells. QS-21 can activate the NLRP3 inflammasome with subsequent release of caspase-1 dependent cytokines, IL-1β and IL-18 |
CFN91587 | Pteroic acid Pteroic acid causes greater stimulation of FPGS, including glutamylation of tetrahydrofolate, at neutral pH values (i.e., below the pH optimum of 8.4). |
CFN91586 | Fabacein |
CFN91585 | Anisomycin Anisomycin is a bacterial antibiotic isolated from Streptomyces griseolus, which inhibits protein synthesis, and also act as a JNK activator. Anisomycin upregulates autophagy and increases apoptosis. |
CFN91584 | Creatinine Phosphate Disodium Salt |
CFN91583 | Potassium Hydroxycitrate HCA-SX has been shown to increase serotonin availability, reduce appetite, increase fat oxidation, improve blood lipid levels, reduce body weight, and modulate a number of obesity regulatory genes without affecting the mitochondrial and nuclear proteins required for normal biochemical and physiological functions. |
CFN91582 | Cholest-4,6-diene-3-ol |
CFN95414 | 3',4',5',5,7-Pentamethoxyflavanone one of the most active as glyceraldehyde-3-phosphate dehydrogenase-inhibitor. |
CFN95415 | 5-Demethylsinensetin 5-desmethylsinensetin, possesses antiprotozoal activity. 5-desmethylsinensetin shows IC50 values of 0.4 μg/mL on T. cruzi epimastigotes and 75.1 μg/mL on trypomastigotes, respectively |
CFN95416 | Erythro-Guaiacylglycerol-beta-coniferyl aldehyde ether Erythro-Guaiacylglycerol-beta-coniferyl aldehyde ether,cytotoxic effects on human cancer cell lines |
CFN95417 | threo-Guaiacylglycerol-beta-coniferyl aldehyde ether the absolute configurations of guaiacylglycerol-β-coniferyl aldehyde ether had an impact on the inhibitory effect on Hep3B cells. The inactivation of MEK/ERK signaling pathway might contribute to apoptosis induction and ROS generation in guaiacylglycerol-β-coniferyl aldehyde ether-treated cells. |
CFN95418 | Naringin 6''-acetate |
CFN95419 | Melitidin Melitidin was discovered in bergamot orange juice and exhibits statin-like properties,so the juice seems to have hypolipidemic activity. |
CFN00518 | 7-O-Acetylintermedine N-oxide 7-O-Acetylintermedine-N-oxide is a pyrrolizidine alkaloid isolated from Symphytum officinale. Pyrrolizidine alkaloids have adverse health effects and were classified as genotoxic, carcinogen and hepatotoxic. |
CFN95420 | Citrusin C citrusin c is a potential natural inhibitor against human serum albumin (SA) |
CFN95421 | Narirutin 4'-glucoside |
CFN95422 | Bergamjuicin Bergamjuicin is a flavonoid isolated from Citrus grandis L. Osbeck with cellular antioxidant activity (CAA) and oxygen radical absorption capacity (ORAC). |
CFN91581 | N-Vanillyloctanamide N-Vanillyloctanamide, a capsaicin, dose-dependently reduces free radical length in lettuce seedlings |
CFN95423 | Norwogonin-8-O-glucuronide Norwogonin-8-O-glucuronide has anti-inflammatory activity. |
CFN95424 | 3-Hydroxymollugin 3-Hydroxymollugin are cytotoxic compounds isolated from Pentas longiflora and Rubia cordifolia. |
CFN95425 | 1,3,4,6-Tetragalloylglucose |
CFN95426 | Annphenone Annphenone exhibits antioxidant properties by inhibiting ROS generation and thus protecting cells from H2O2-induced cell damage. |
CFN95427 | Benzyl beta-D-glucopyranoside Benzyl β-D-glucopyranoside exhibits strong PTP1B enzyme inhibition (IC50 = 6.97) and antioxidant activity.Benzyl beta-D-glucopyranoside contribute to relieving the tension in M-rats caused by ether stress. |
CFN95428 | 2,11,12-Trihydroxy-7,20-epoxy-8,11,13-abietatriene |
CFN95429 | 2-Phenylethyl-beta-glucopyranoside Beta-glucosidase was highly specific for 2-phenylethyl beta-D-glucopyranoside. |
CFN95430 | 4-O-Caffeoyl-3-O-syringoylquinic acid |
CFN95431 | Umbelliferone 7-O-rutinoside |
CFN95432 | Crepidiaside B |
CFN95433 | 11beta,13-Dihydrolactucin 11beta,13-Dihydrolactucin has analgesic effect and anti-inflammatory potential . |
CFN95434 | Jacquilenin Jacquilenin has anti-inflammatory activity |
CFN95435 | Naringenin 7-O-gentiobioside |
CFN91580 | Arganine E |
CFN95436 | Cannabisin M |
CFN95437 | Moreollic acid Moreollic acid has moderate antibacterial activity against methicillin-resistant Staphylococcus aureus with an MIC of 25 microg/ml. Moreollic acid has antitumor activity. |
CFN95438 | Epigambogellic acid Epigambogellic acid has antitumor activity and inhibits SMMC-7221 cells and A549 cells. |
CFN95439 | Gambogoic acid A |
CFN95440 | Isogambogic acid Isogambogic acid shows cytotoxic activiity against KB and drug-resistant KB-V1 cell lines. Isogambogic acid has anticancer activity. |
CFN95441 | Oleracein E Oleracein E (OE), a tetrahydroisoquinoline, has potent antioxidant and anti-apoptotic activities. Olivine E is cardioprotective and neuroprotective.Oleracein E has the effect of improving cognitive function. Oleracein E exhibits moderate antibacterial activity. Oleracein E showed significant cytotoxicity against HepG2,with its inhibitory rate of 52.2% at 10 micromol x L(-1). Oleracein E has an osteogenic effect. TRP-1 (Oleracein E) strongly accelerates the Treg proliferation in vitro in a concentration-dependent manner. |
CFN95442 | Orthosiphol A Orthosiphol A showed a significant dose-dependent inhibitory effect on nitric oxide (NO) production in lipopolysaccharide (LPS)-activated macrophage-like J774.1 cells. Orthosiphol A has anticancer effects. Orthosiphol A selectively inhibited intestinal maltase with an IC5o, value of 6.54 mM. |
CFN95443 | Fragransin B1 Fragransin B1 has antiprotozoal activity and is cytotoxic to rat myoblast L6 cells. |
CFN95444 | Pinocembroside Pinocembrin-7-O-β-D-glucopyranoside (Pinocembrin 7-O-β-D-Glucoside) is a flavonoid compound that enhances lipid peroxidation |
CFN95445 | Elgonica dimer A |
CFN95446 | 4-Methoxybenzoylacetic acid |
CFN95447 | Neoorthosiphol A Neoorthosiphol A inhibits rat thoracic aortic systolic response. Neoorthosiphol A shows antiprolifer-ative activity against highly hepatic metastatic colon 26-L5 carcinoma and the human HT-1080 fibrosarcoma cell line. |
CFN95448 | Cajanine Cajanine, a stilbenic component isolated from Cajanus cajan L., was identified as a potent HCV inhibitor (EC50 = 3.17 ± 0.75 μM). Cajanine promotes osteogenic differentiation and proliferation of human bone marrow mesenchymal stem cells. Cajanine promotes osteoblast proliferation and mineralized osteoid tissue formation in HOS TE85 cells, while inhibiting osteoclast derivation. |
CFN91579 | Benzoylalbiflorin Benzoylalbiflorin, a monoterpenoid, is isolated from Radix Paeoniae Alba. Radix Paeoniae Alba is a traditional Chinese medicine that has been used for the research of rheumatoid arthritis, to alleviate inflammation, amenorrhea, epistaxis, abdominal pain, and other symptoms. |
CFN91578 | Phenoxodiol Phenoxodiol, a synthetic analog of Genestein, activates the mitochondrial caspase system, inhibits XIAP (an apoptosis inhibitor), and sensitizes the cancer cells to Fas-mediated apoptosis. This agent also inhibits DNA topoisomerase II by stabilizing the cleavable complex. Phenoxodiol induces cell cycle arrest in the G1/S phase of the cell cycle and upregulates p21WAF1 via a p53 independent manner. |