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15-Nor-14-oxolabda-8(17),12-dien-18-oic acid
15-Nor-14-oxolabda-8(17),12-dien-18-oic acid
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 15-Nor-14-oxolabda-8(17),12-dien-18-oic acid
Price:
CAS No.: 1039673-32-9
Catalog No.: CFN99058
Molecular Formula: C19H28O3
Molecular Weight: 304.4 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The barks of Pinus yunnanensis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: 15-Nor-14-oxolabda-8(17),12 E-diene-18-oic acid shows antibacterial (Propionibacterium acnes) and antifungal activities.
Targets: Antifection
In vitro:
Planta Med. 2008 Mar;74(4):449-52.
Labdane-type diterpenes active against acne from pine cones (Pinus densiflora).[Pubmed: 18484541]

METHODS AND RESULTS:
Bioassay-guided extraction and fractionation of the aqueous methanolic extract of the cones of Pinus densiflora (Pinaceae) afforded one new labdane-type diterpene aldehyde, 15-nor-14-oxolabda-8(17),12 E-diene-18-oic acid(15-Nor-14-oxolabda-8(17),12-dien-18-oic acid ), along with eight known diterpenes. Their structures were elucidated using spectroscopic methods as well as by comparison with previously reported data.
CONCLUSIONS:
The isolates showed antibacterial (Propionibacterium acnes) and antifungal activities.
15-Nor-14-oxolabda-8(17),12-dien-18-oic acid Description
Source: The barks of Pinus yunnanensis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.2852 mL 16.4258 mL 32.8515 mL 65.703 mL 82.1288 mL
5 mM 0.657 mL 3.2852 mL 6.5703 mL 13.1406 mL 16.4258 mL
10 mM 0.3285 mL 1.6426 mL 3.2852 mL 6.5703 mL 8.2129 mL
50 mM 0.0657 mL 0.3285 mL 0.657 mL 1.3141 mL 1.6426 mL
100 mM 0.0329 mL 0.1643 mL 0.3285 mL 0.657 mL 0.8213 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
ar-Turmerone

Catalog No: CFN89231
CAS No: 532-65-0
Price: $238/20mg
Aloenin A

Catalog No: CFN93235
CAS No: 38412-46-3
Price: $ / mg
Notoginsenoside Fe

Catalog No: CFN93282
CAS No: 88105-29-7
Price: $100/20mg
Cyanidin-3-O-galactoside chloride

Catalog No: CFN92040
CAS No: 27661-36-5
Price: $318/10mg
alpha-Viniferin

Catalog No: CFN97068
CAS No: 62218-13-7
Price: $318/10mg
Agnuside

Catalog No: CFN99203
CAS No: 11027-63-7
Price: $168/20mg
6-Prenylnaringenin

Catalog No: CFN92017
CAS No: 68236-13-5
Price: $268/10 mg
L-Citruline

Catalog No: CFN90551
CAS No: 372-75-8
Price: $30/20mg
Higenamine

Catalog No: CFN93353
CAS No: 5843-65-2
Price: $80/20mg
Evodiamine

Catalog No: CFN99993
CAS No: 518-17-2
Price: $40/20mg
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