Structure Identification: |
Yao Xue Xue Bao. 2011 Jul;46(7):818-21. | Chemical constituents from Salvia przewalskii Maxim.[Pubmed: 22010351] | The investigation on Salvia przewalskii Maxim was carried out to find the relationship of the constituents and their pharmacological activities.
METHODS AND RESULTS:
The isolation and purification were performed by various chromatographies such as silica gel, Sephadex LH-20, RP-C18 column chromatography, etc. Further investigation on the fraction of the 95% ethanol extract of Salvia przewalskii Maxim yielded przewalskin Y-1 (1), anhydride of tanshinone-II A (2), sugiol (3), epiCryptoacetalide (4), Cryptoacetalide (5), arucadiol (6), 1-dehydromiltirone (7), miltirone (8), cryptotanshinone (9), tanshinone II A (10) and isotanshinone-I (11). Their structures were elucidated by the spectral analysis such as NMR (Nuclear Magnetic Resonance) and MS (Mass Spectrometry).
CONCLUSIONS:
Compound 1 is a new compound. Compounds 4 and 5 are mirror isomers (1 : 3). Compounds 4, 5, 6, 8, 11 were isolated from Salvia przewalskii Maxim for the first time. |
|