Science | Nature | Cell | View More
Natural Products
Pancixanthone A
Pancixanthone A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Pancixanthone A
Price:
CAS No.: 174232-30-5
Catalog No.: CFN89085
Molecular Formula: C18H16O5
Molecular Weight: 312.32 g/mol
Purity: >=98%
Type of Compound: Xanthones
Physical Desc.: Powder
Source: The leaves of Calophyllum inophyllum Linn.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Florida A&M University (USA)
  • University of Mysore (India)
  • Pennsylvania State University (USA)
  • University of Maryland School o... (USA)
  • Complutense University of Madrid (Spain)
  • Uniwersytet JagielloĊ„ski w Kra... (Poland)
  • University of South Australia (Australia)
  • University of Queensland (Australia)
  • Korea Intitute of Science and T... (Korea)
  • Ateneo de Manila University (Philippines)
  • University of Canterbury (New Zealand)
  • More...
Package
Featured Products
Rhynchophylline

Catalog No: CFN98131
CAS No: 76-66-4
Price: $98/20mg
10-Shogaol

Catalog No: CFN92300
CAS No: 36752-54-2
Price: $138/20mg
Catechin

Catalog No: CFN99646
CAS No: 154-23-4
Price: $30/20mg
Rhamnocitrin

Catalog No: CFN97724
CAS No: 569-92-6
Price: $268/10mg
Doxycycline

Catalog No: CFN90251
CAS No: 564-25-0
Price: $ /
Isoschaftoside

Catalog No: CFN92029
CAS No: 52012-29-0
Price: $118/20mg
Tiliroside

Catalog No: CFN98026
CAS No: 20316-62-5
Price: $70/20mg
Shikonin

Catalog No: CFN99907
CAS No: 517-88-4
Price: $50/20mg
Coronaridine

Catalog No: CFN92859
CAS No: 467-77-6
Price: $ / mg
Erythrodiol

Catalog No: CFN98914
CAS No: 545-48-2
Price: $138/10mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Pancixanthone A may have antimalarial activity, it also shows a significant antileishmanial activity against the promastigote forms of Leishmania mexicana and L. infantum and against the amastigote forms of L. infantum.
Targets: Antifection
In vitro:
Fitoterapia. 2008 Jan;79(1):42-6.
Antileishmanial polyphenols from Garcinia vieillardii.[Pubmed: 17826924 ]

METHODS AND RESULTS:
Seven xanthones, the new vieillardiixanthones B and C (1) and (7), Pancixanthone A (2),pancixanthone B (3), 1,6-dihydroxyxanthone (6), pyranojacareubin and 5,6-O-dimethyl-2-deprenylrheediaxanthone together with two benzophenones, clusiachromene (4) and 3-geranyl-2,4,6-trihydroxybenzophenone (5) were isolated from the stem bark of the neocaledonian Garcinia vieillardii.
CONCLUSIONS:
2, 5 and 6 showed a significant antileishmanial activity against the promastigote forms of Leishmania mexicana and L. infantum and against the amastigote forms of L. infantum.
Pancixanthone A Description
Source: The leaves of Calophyllum inophyllum Linn.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Odontoside

Catalog No: CFN95530
CAS No: 20300-50-9
Price: $318/5mg
Gypenoside XIII

Catalog No: CFN95239
CAS No: 80325-22-0
Price: $288/10mg
Pilosidine

Catalog No: CFN95110
CAS No: 229971-57-7
Price: $413/5mg
4'-Hydroxy-5,7,3'-trimethoxyflavon...

Catalog No: CFN95398
CAS No: 1239-68-5
Price: $318/5mg
1,7-Diphenyl-5-hydroxy-4,6-hepten-...

Catalog No: CFN95171
CAS No: 87095-77-0
Price: $318/10mg
Melitidin

Catalog No: CFN95419
CAS No: 1162664-58-5
Price: $318/10mg
Lariciresinol 4'-O-glucoside

Catalog No: CFN95400
CAS No: 107110-16-7
Price: $318/5mg
4-Hydroxybenzoyl choline

Catalog No: CFN95158
CAS No: 5094-31-5
Price: $318/20mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.2018 mL 16.0092 mL 32.0184 mL 64.0369 mL 80.0461 mL
5 mM 0.6404 mL 3.2018 mL 6.4037 mL 12.8074 mL 16.0092 mL
10 mM 0.3202 mL 1.6009 mL 3.2018 mL 6.4037 mL 8.0046 mL
50 mM 0.064 mL 0.3202 mL 0.6404 mL 1.2807 mL 1.6009 mL
100 mM 0.032 mL 0.1601 mL 0.3202 mL 0.6404 mL 0.8005 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Yao Xue Xue Bao. 2009 Feb;44(2):154-7.
Xanthones from leaves of Calophyllum inophyllum Linn.[Pubmed: 19408685]

METHODS AND RESULTS:
To study the xanthones from the leaves of Calophyllum inophyllum Linn., several chromatography methods were employed to isolate the constituents. Investigation on the CHCl3 extract led to the isolation of a new xanthone named inophyxanthone A (1) and four known compounds, which were Pancixanthone A (2), gerontoxanthone B (3), jacareubin (4) and pyranojacareubin (5). Among them, compound 2 was obtained from this plant firstly, and compound 3 was obtained for the first time from this genus.
CONCLUSIONS:
The structure of inophyxanthone A (1) was identified as 1, 3, 5-trihydroxy-2-(1, 1-dimethylallyl)xanthone by spectral analysis.
Life Sci. 2004 Nov 5;75(25):3077-85.
Antimalarial xanthones from Calophyllum caledonicum and Garcinia vieillardii.[Pubmed: 15474559 ]

METHODS AND RESULTS:
The antimalarial activity of 22 xanthones against chloroquino-resistant strains of Plasmodium falciparum was evaluated. Natural caloxanthone C (1), demethylcalabaxanthone (2), calothwaitesixanthone (3), calozeyloxanthone (4), dombakinaxanthone (5), macluraxanthone (6), and 6-deoxy-gamma-mangostin (7) were isolated from Calophyllum caledonicum. 1,6-dihydroxyxanthone (8), Pancixanthone A (9), isocudraniaxanthone B (10), isocudraniaxanthone A (11), 2-deprenylrheediaxanthone B (12) and 1,4,5-trihydroxyxanthone (13) were isolated from Garcinia vieillardii. Moreover, synthetic compounds (14-22) are analogues or intermediates of xanthones purified from Calophyllum caledonicum. The relationship between antimalarial activity and molecular structure of xanthones has also been explored.
CONCLUSIONS:
The most potent xanthones (2), (3) and (7) (IC50 = c.a. 1.0 microg/mL) are 1,3,7 trioxygenated and prenylated on the positions 2 and 8.
Rhynchophylline

Catalog No: CFN98131
CAS No: 76-66-4
Price: $98/20mg
10-Shogaol

Catalog No: CFN92300
CAS No: 36752-54-2
Price: $138/20mg
Catechin

Catalog No: CFN99646
CAS No: 154-23-4
Price: $30/20mg
Rhamnocitrin

Catalog No: CFN97724
CAS No: 569-92-6
Price: $268/10mg
Doxycycline

Catalog No: CFN90251
CAS No: 564-25-0
Price: $ /
Isoschaftoside

Catalog No: CFN92029
CAS No: 52012-29-0
Price: $118/20mg
Tiliroside

Catalog No: CFN98026
CAS No: 20316-62-5
Price: $70/20mg
Shikonin

Catalog No: CFN99907
CAS No: 517-88-4
Price: $50/20mg
Coronaridine

Catalog No: CFN92859
CAS No: 467-77-6
Price: $ / mg
Erythrodiol

Catalog No: CFN98914
CAS No: 545-48-2
Price: $138/10mg
Tags: buy Pancixanthone A | Pancixanthone A supplier | purchase Pancixanthone A | Pancixanthone A cost | Pancixanthone A manufacturer | order Pancixanthone A | Pancixanthone A distributor