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Pterisolic acid A
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Product Name Pterisolic acid A
Price:
CAS No.: 1401419-85-9
Catalog No.: CFN97975
Molecular Formula: C20H26O5
Molecular Weight: 346.4 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The herbs of Pteris semipinnata.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
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10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Pterisolic acid A shows moderate activity against HCT-116,Hep G2 and BGC-823 cell lines.
In vitro:
China Journal of Chinese Materia Medica, 2016, 41(24):4610-4.
Chemical constituents from Pteris multifida and cytotoxic activity[Reference: WebLink]

METHODS AND RESULTS:
The materials were extracted by 95% ethanol,and the extracting solution was isolated by kinds of chromatographic columns including polyamide, MCI,preparative MPLC,and preparative HPLC. Eight diterpenes and two sesquiterpenes were isolated from the plant. On analysis of ESI-MS and NMR spectroscopic data,the structures were established as ent-3β-hydroxy-kaur-16-en-19-al( 1),4-epi-kaurenic acid( 2),mitrekaurenone( 3),7β,16α,17-trihydroxy-ent-kauran-19-oic acid( 4),crotonkinin E( 5),crotonkinin F( 6),Pterisolic acid A( 7),pterisolic acid C( 8),( 2R)-pterosin P( 9),and dehydropterosin B( 10).
CONCLUSIONS:
Compounds 1-6 were obtained from Pteris for the first time,and compounds 7-10 were obtained from P. ensiformis for the first time. Compounds 5-8 showed moderate activity against HCT-116,Hep G2 and BGC-823 cell lines,separately.
Pterisolic acid A Description
Source: The herbs of Pteris semipinnata.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

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Mol Cell. 2017 Nov 16;68(4):673-685.e6.
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ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
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PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.8868 mL 14.4342 mL 28.8684 mL 57.7367 mL 72.1709 mL
5 mM 0.5774 mL 2.8868 mL 5.7737 mL 11.5473 mL 14.4342 mL
10 mM 0.2887 mL 1.4434 mL 2.8868 mL 5.7737 mL 7.2171 mL
50 mM 0.0577 mL 0.2887 mL 0.5774 mL 1.1547 mL 1.4434 mL
100 mM 0.0289 mL 0.1443 mL 0.2887 mL 0.5774 mL 0.7217 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Citric acid

Catalog No: CFN98551
CAS No: 77-92-9
Price: $30/20mg
Aucubin

Catalog No: CFN98530
CAS No: 479-98-1
Price: $60/20mg
Calycosin

Catalog No: CFN99140
CAS No: 20575-57-9
Price: $80/20mg
Sinigrin

Catalog No: CFN90453
CAS No: 3952-98-5
Price: $80/20mg
Ganoderol B

Catalog No: CFN99064
CAS No: 104700-96-1
Price: $318/5mg
Retronecine

Catalog No: CFN00322
CAS No: 480-85-3
Price: $ /
Falcarinol

Catalog No: CFN96027
CAS No: 21852-80-2
Price: $218/20mg
Neferine

Catalog No: CFN99581
CAS No: 2292-16-2
Price: $70/20mg
Phyllanthin

Catalog No: CFN99050
CAS No: 10351-88-9
Price: $288/10mg
Isochlorogenic acid C(4,5)

Catalog No: CFN90354
CAS No: 57378-72-0
Price: $60/20mg
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