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Scutebata F
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Product Name Scutebata F
Price:
CAS No.: 1207181-62-1
Catalog No.: CFN99326
Molecular Formula: C30H37NO9
Molecular Weight: 555.6 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The herbs of Scutellaria barbata D.Don
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Reference standards.
In vitro:
Journal of Natural Products, 2010, 73(2):233-236.
Cytotoxic neoclerodane diterpenoids from Scutellaria barbata.[Reference: WebLink]

METHODS AND RESULTS:
Seven new neoclerodane diterpenoids, scutebata A, scutebata B, scutebata C, scutebata D, scutebata E, Scutebata F, scutebata G (1-7), have been isolated from Scutellaria barbata. Compounds 1-3 possess a rare alpha-hydroxy group in their alpha,beta-unsaturated lactone rings. Their structures were elucidated by spectroscopic analysis, and the relative configuration of scutebata A was deduced using ROESY data and the computational DFT method. Compounds 1, 2, 4, 5, and 6 were evaluated for in vitro cytotoxicity against six human cancer cell lines: HL-60, SMMC-7721, A-549, SK-BR-3, CACO-2, and PANC-1.
CONCLUSIONS:
Scutebata A (1) showed weak cytotoxicity against SK-BR-3 with an IC(50) value of 15.2 muM.
Scutebata F Description
Source: The herbs of Scutellaria barbata D.Don
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

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Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.7999 mL 8.9993 mL 17.9986 mL 35.9971 mL 44.9964 mL
5 mM 0.36 mL 1.7999 mL 3.5997 mL 7.1994 mL 8.9993 mL
10 mM 0.18 mL 0.8999 mL 1.7999 mL 3.5997 mL 4.4996 mL
50 mM 0.036 mL 0.18 mL 0.36 mL 0.7199 mL 0.8999 mL
100 mM 0.018 mL 0.09 mL 0.18 mL 0.36 mL 0.45 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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Sugiol

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(2-Acetoxyethyl)trimethylammonium

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Luteolin-4'-O-glucoside

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