Natural Products
| Catalog No. | Information |
| CFN99685 | 3-Hydroxy-5,7-dimethoxy-3',4'-methylenedioxyflavan Reference standards. |
| CFN99686 | Kaempferol tetraacetate Kaempferol tetraacetate is a potent antiplatelet agent. It exhibits significant cytotoxicity in vitro against three human cell lines HL-60, U937 and SK-MEL-1. |
| CFN99687 | 3,4-Dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran Reference standards. |
| CFN99688 | 1-Hydroxy-2-prenylnaphthalene Reference standards. |
| CFN99689 | Yunnancoronarin A Yunnancoronarin A shows cytotoxicity against the lung adenocarcinoma cells A549 and leukemia cells K562, with the IC(50) value of 2.20 microM. |
| CFN99690 | Triptoquinonide Triptoquinonide is a natural product from Tripterygium wilfordii. |
| CFN99691 | Clerodenoside A Clerodenoside A has antioxidant activity. |
| CFN99692 | 4-(3,4-Dimethoxyphenyl)-3-butene-1,2-diol Reference standards. |
| CFN99693 | Calyxin B Calyxin B exhibits potent activity against human HT-1080 fibrosarcoma cells with an ED50 value of 0.69 microM. A methylated product of calyxin A and an epimeric mixture of Calyxin B, showed greatly reduced activity suggesting that phenolic hydroxyl groups are involved in the inhibitory activity. |
| CFN99694 | Brevilin A Brevilin A is a strong impetus for the development of selective JAK-STAT inhibitors and therapeutic drugs in order to improve survival of patients with hyperactivated JAKs and STATs. Brevilin A shows antigiardial activity (IC50 = 16.1 μM) and is similarly active in vitro against Entamoeba histolytica (IC50 between 4.5 and 9 μM) and against Plasmodium falciparum (IC50 = 9.42 μM). |
| CFN99695 | 6-Epidemethylesquirolin D Reference standards. |
| CFN99696 | Cleroindicin E Reference standards. |
| CFN99697 | Hemiphroside A Hemiphroside A is a natural product from Hydrangea macrophylla. |
| CFN99698 | Hemiphroside B Reference standards. |
| CFN99699 | Methyl 6-acetoxyangolensate Methyl-6-acetoxy angolensate may have antimalarial activity. |
| CFN99700 | 9-O-Feruloyl-5,5'-dimethoxylariciresinol (+)-9'-O-trans-feruloyl-5,5'-dimethoxylariciresinol may have anti-allergic inflammatory effect, it can inhibit release of histamine from mast cells. It shows cytotoxicity against a small panel of human tumor cell lines, with ED50 values of 9.86 to approximately 12.68 microg/ml. |
| CFN99801 | Rubelloside B Rubelloside B exhibits immunological enhancement effect. |
| CFN99802 | Wilforol C Reference standards. |
| CFN99803 | Evofolin B Evofolin B exhibits quinone reductase (QR) inducing activity, with observed CD (concentration required to double induction) values of 16.4 microM. |
| CFN99804 | C-Veratroylglycol C-Veratroylglycol shows antioxidant activity (IC50<100 uM). |
| CFN99805 | Oxymatrine Oxymatrine has exhibited anti-hepatitis virus infection, anti-hepatic fibrosis, anti-inflammation, anti-anaphylaxis and other immune-regulation, it induces human pancreatic cancer PANC-1 cells apoptosis via regulating expression of Bcl-2 and IAP families, and releasing of cytochrome C. It can attenuate diabetes-associated cognitive deficits in rats, which is associated with oxidative stress, inflammation and apoptotic cascades, it is proven to protect ischemic and reperfusion injury in liver, intestine and heart. |
| CFN99767 | Ethyl ferulate Ethyl ferulate has anti-inflammatory property, can reduce HIV replication, it shows inhibitive effect on platelet congregation induced by ADP. It also is a potent inducer of HO-1 for the protection of brain cells against oxidative and neurodegenerative conditions. |
| CFN99768 | Theophylline Theophylline is a competitive nonselective phosphodiesterase inhibitor and nonselective adenosine receptor antagonist, which is the most widely used anti-asthma drug worldwide and is classified as a bronchodilator. It has antiinflammatory, and immunomodulatory actions, it also can antagonize flurazepam-induced depression of cerebral cortical neurons. |
| CFN99769 | D-(+)-Glucose Dextrose, a simple sugar (monosaccharide), is an important carbohydrate in biology, it exhibits marked antibacterial activity against Staphylococcus aureus,Escherichia coli and Pyocyanine. D-(+)-Glucose can prevent MPP+ toxicity, attenuate the loss of ATP, but do not reverse the complete inhibition of mitochondrial O2 consumption (MOC). |
| CFN99770 | Dehydroandrographolide Dehydroandrographolide is a novel TMEM16A inhibitor and possesses multiple pharmacological activities, including anti-inflammation, anti-cancer, anti-bacterial, anti-virus and anti-hepatitis activity. It possesses activity against HBV DNA replication with IC50 values of 22.58 uM and low SI values of 8.7 ; it can alleviate oxidative stress in LPS-induced acute lung injury possibly by inactivating iNOS. |
| CFN99771 | Quercetin-7-O-beta-D-glucopyranoside Quercetin-7-O-beta-D-glucopyranoside has antibacterial activity, it shows promising activity against Staphylococcus aureus. Quercetin 7-O-beta-D-glucopyranoside exhibits strong antioxidative, and anti-inflammatory activities, inhibiting expression of inducible nitric oxide synthase and release of nitric oxide by lipopolysaccharide-stimulated RAW 264.7 macrophages in a dose-dependent manner. It inhibits overexpression of cyclooxygenase-2 and granulocyte macrophage-colony-stimulating factor. |
| CFN99772 | Grosvenorin Grosvenorine exhibits good antibacterial and antioxidant activities, with its metabolites possessing more potent activities, intestinal bacteria play an important role in the gastrointestinal metabolism of grosvenorine and significantly affect its pharmacological activities. |
| CFN99773 | Narcissoside Narcissoside is a good 15-LO and α-glucosidase inhibitor, it with synergism of B.flavum flavonoid and rutin, could be responsible for stronger protection against mitochondrial induced oxidative stress. |
| CFN99774 | Albiflorin Albiflorin has anti-inflammatory, and antidepressant-like effects. Albiflorin may reduce or prevent osteoblast degeneration in osteoporosis, and may promote the recovery of bone marrow hemopoietic function in a myelosuppressed mouse model, it has neuroprotective effect on primary hippocampal cells against β-amyloid induced toxicity. |
| CFN99775 | Alismoxide Alismoxide shows an inhibitory effect on the contraction of isolated bladder smooth muscle induced by carbachol; it demonstrates cytostatic action in HeLa cells, revealing potential use in virostatic cocktails. Alismoxide has inhibitory effects on vascular contraction induced by high concentration of KCl; it also shows an inhibitory effect on the direct passive Arthus reaction (DPAR) in rats in the type III allergic model. |
| CFN99806 | Epifriedelanol Epifriedelanol has antitumor activity, it can reduce cellular senescence in human primary cells and may be used to develop dietary supplements or cosmetics that modulate tissue aging or aging-associated diseases. Epifriedelanol exhibits significant inhibition of NF-kappa B, it may be used to treat asthma. |
| CFN99807 | Odoratone Odoratone shows insecticidal activities, it shows mortality on fourth instar larvae of mosquitoes (Anopheles stephensi) with LC(50) values of 154 ppm. Odoratone exhibits strong antifeedant activity against Pieris brassicae. |
| CFN99808 | Bauerenol acetate Reference standards. |
| CFN99809 | Nitidanin (±)-Nitidanin is an antimalarial compound. |
| CFN99810 | 2-Hydroxy-3-methylanthraquinone 2-Hydroxy-3-methylanthraquinone enhances apoptosis of U937 cells,in part,through activation of p-p38MAPK and downregulation of p-ERK1/2; triggers caspase-3 activation mediated apoptotic induction. |
| CFN99811 | Coumurrayin Coumurrayin may have anticoagulant activity. |
| CFN99812 | 3',4',5',3,5,6,7-Heptamethoxyflavone Reference standards. |
| CFN99813 | Eucalyptone Eucalyptone is a natural product from Eucalyptus globulus. |
| CFN99814 | Rhoifolin Rhoifolin possesses a variety of significant biological activities including antioxidant, anti-inflammatory, antimicrobial, hepatoprotective and anticancer effects, it may be beneficial for diabetic complications through its enhanced adiponectin secretion, tyrosine phosphorylation of insulin receptor-β and GLUT4 translocation. Rhoifolin has a radioprotective effect against radiation-induced decrease of blood platelets and cardiac biochemical lesions in whole body irradiated mice. |
| CFN99815 | Ganoderic acid DM Ganoderic acid DM is an antiandrogenic osteoclastogenesis inhibitor, it especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 (NFATc1), this suppression leads to the inhibition of dendritic cell-specific transmembrane protein (DC-STAMP) expression and reduces osteoclast fusion. Ganoderic acid DM has shown toxicity to both androgen-dependent and independent prostate cancer cells with reduced osteoclastogenesis in late stage metastatic disease, it may an alternative agent for the treatment of advanced prostate cancer. |
| CFN99816 | Garciniaxanthone E The synthetic caged Garcinia xanthone cluvenone induces cell stress and apoptosis and has immune modulatory activity. |
| CFN99817 | Ficusin A Ficusin has antioxidant, antilipidemic and antidiabetic effects, it can lower the levels of fasting blood glucose, plasma insulin, body weight gain in HFD-STZ induced diabetic rats, and can significantly enhance the PPARγ expression and improve the translocation and activation of GLUT4 in the adipose tissue, suggests that ficusin improves the insulin sensitivity on adipose tissue and it can be used for the treatment of obesity related type 2 diabetes mellitusl. |
| CFN99818 | Swertiamarin Swertiamarin possesses anti-hyperglycemic, anti-hyperlipidemic, anti-diabetic activity and enhances β cell regeneration which causes reversal of diabetes. Swertiamarin also possesses significant wound healing, anti-inflammatory, antioxidant, hepatoprotective, peripheral and central antinociceptive properties. Swertiamarin inhibits the development of arthritis by modulating NF-κB/IκB and JAK2/STAT3 signaling, it acts as an anti-rheumatic agent. |
| CFN99819 | Isocarapanaubine Isocarapanaubine and reserpiline are cytotoxic constituents from the barks of Ochrosia elliptica. |
| CFN99820 | Tanshinone IIB Co-treatment with Tanshinone IIB (TSB) significantly inhibits the DNA laddering, cytotoxicity and apoptosis of rat cortical neurons induced by staurosporine in a concentration-dependent manner; TSB also suppresses the elevated Bax protein and decreased bcl-2 and caspase-3 proteins induced by staurosporine in rat cortical neurons; TSB is effective in reducing stroke-induced brain damage and may represent a novel drug candidate for further development. TSB significantly inhibits the uptake of digoxin and vinblastine in membrane vesicles containing PgP or MRP1, moderately stimulates PgP ATPase activity, suggesting TSB is a substrate for PgP and MRP1 and that drug resistance to TSB therapy and drug interactions may occur through PgP and MRP1 modulation. |
| CFN99776 | N-Methylcytisine N-Methylcytisine's nicotinic receptors have high affinity (KD = 50 nM)to nAChR from squid optical ganglia, N-methylcytisine is a selective ligand of nicotinic receptors of acetylcholine in the central nervous system. (−)-N-methylcytisine and (−)-anagyrine have nematicidal activity against pine wood nematodes. |
| CFN99777 | Sparteine sulfate pentahydrate Reference standards. |
| CFN99778 | Herbacetin Herbacetin, a novel Met inhibitor with a potential utility in cancer therapeutics, suppresses the HGF-induced motility of human breast cancer MDA-MB-231 cells by inhibiting c-Met and Akt phosphorylation. Herbacetin exerts an anti-inflammatory effect through suppression of LPS-induced JNK and NF-κB signaling pathways and diminished production of proinflammatory cytokines and mediators. Herbacetin also has a strong ability to scavenge free radical and inhibit oxidative protein damage. |
| CFN99779 | Sarsasapogenin Sarsasapogenin has antidiabetic, improving memory, antidepressant, anti-oxidative, anticancer and anti-inflamatory activities. It can effectively promote the proliferation,differentiation and mineralization of osteoblasts cultured in vitro, it also can inhibit the generation of osteoclasts from marrow cells. Sarsasapogenin potently inhibited NF-κB and MAPK activation, as well as IRAK1, TAK1, and IκBα phosphorylation in LPS-stimulated macrophages. |
| CFN99780 | Lithospermoside Lithospermoside has anti-oxidant,and anti-tumor promoting activities. |
