Natural Products
| Catalog No. | Information |
| CFN92988 | Angelol G Angelol G is a natural product from Angelica sinensis. |
| CFN92966 | Tamgermanetin Tamgermanetin demonstrates potential cytotoxic effect against three different tumor cell lines, namely liver (Huh-7), breast (MCF-7) and prostate (PC-3). |
| CFN92961 | Curculigoside B Curculigoside B shows antioxidative and antiosteoporotic activities, it can decrease area of bone resorption pit, osteoclastic formation and TRAP activity. |
| CFN92950 | 5-O-Caffeoylshikimic acid 5-O-Caffeoylshikimic acid shows anti-oxidative activity; it also shows anti-inflammatory activity, the underlying mechanism was associated with downregulation of nuclear factor-κB. 5-O-Caffeoylshikimic acid can remarkably inhibit the macrophage migration and adhesion. It also shows moderate MDR reversal activity. |
| CFN92940 | Physalin A Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling, it inhibits androgen-independent prostate cancer cell growth through activation of cell apoptosis and downregulation of androgen receptor expression. Physalin A induces apoptosis via p53-Noxa-mediated ROS generation, and autophagy plays a protective role against apoptosis through p38-NF-κB survival pathway in A375-S2 cells. |
| CFN92939 | Physalin D Physalin D shows antimalarial activity; it also exhibits a minimum inhibitory concentration value (MIC) against Mycobacterium tuberculosis H(37)Rv strain of 32 microg/mL. Physalin D displays considerable cytotoxicity against several cancer cell lines. It presents antinociceptive properties associated with central. |
| CFN92936 | Isophysalin A Isophysalin A exhibits anti-inflammatory activitiy, it exhibits conjugating abilities with glutathione and also shows significant nitric oxide (NO) production inhibiting activities. |
| CFN92916 | Silybin B Silybin B and silybin A are potent inhibitors of both raloxifene 4'- and 6-glucuronidation in all enzyme systems; they show strong effects on cell growth inhibition and apoptosis induction in human chronic myeloid leukemia K562 cells. Silybin B exhibits 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity. |
| CFN92915 | Licoricesaponin G2 Licoricesaponin G2 has the anti-inflammatory effects as NF-κB inhibitors, it has anti-HIV activity via significantly interacted with R15K. |
| CFN90984 | Rebaudioside G Reference standards. |
| CFN90965 | Isoscoparin Isoscoparin has antioxidant, and anti-adipogenic effects, it may be a potential therapeutic agent for the prevention and treatment of obesity. Isoscoparin can significantly inhibit the production of both NO and TNF-α at a concentration of 2.0 uM. |
| CFN90958 | Sophorabioside Sophorabioside is a natural product from Sophora japonica. |
| CFN90953 | Genistein 7,4'-di-O-beta-D-glucopyranoside Genistein 7,4'-di-O-beta-D-glucopyranoside shows significant estrogenic proliferative effect in MCF-7 cell in sub-cytotoxic concentration range. |
| CFN90949 | Epimagnolin A Epimagnolin A affects the transport activity of ABCB1(a major transmembrane efflux pump belonging to the ABC transporter superfamily), it also exhibits growth inhibitory activity against larvae of Drosophila melanogaster. |
| CFN90945 | Cheilanthifoline Cheilanthifoline has anti-osteoclastogenic property, it gives significant inhibitions on receptor activator of nuclear factor-κB ligand-induced differentiation of mouse bone marrow-derived macrophages into multinucleated osteoclasts. Cheilanthifoline also shows promising in vitro antiplasmodial activities against Plasmodium falciparum. |
| CFN90943 | Isovitexin 2''-O-arabinoside Isovitexin 2''-O-arabinoside is a natural product from Secale cereale. |
| CFN90942 | Kaempferol 3-sophoroside-7-glucoside Kaempferol 3-sophoroside-7-glucoside is a natural product from Equisetum hyemale L. |
| CFN89524 | 2-Hydroxy-4-methoxybenzaldehyde 2-Hydroxy-4-methoxybenzaldehyde is an excellent antimicrobial agent with additional antiaflatoxigenic potency. 2-Hydroxy-4-methoxybenzaldehyde has antioxidant and high antimycotic potency, it possesses chemosensitizing capability to magnify the efficacy of monoterpenoid phenols, which improves target-based (viz., cell wall disruption) antifungal intervention. |
| CFN89520 | Retusin Retusin behaves as pre- and postemergent herbicides. Retusin is a weak inhibitor of ATP synthesis; it exhibits potent free-radical-scavenging capacities as well as efficient inhibition of cellular melanogenesis. |
| CFN89471 | Ambocin Ambocin is a natural product from Pueraria mirifica. |
| CFN89459 | Geissoschizine methyl ether Geissoschizine methyl ether is a potent serotonin ₁A receptor agonist and candidate for amelioration of aggressiveness and sociality by yokukansan, it has third-generation antipsychotic-like actions at the dopamine and serotonin receptors. Geissoschizine methyl ether is a strong acetylcholinesterase (AChE) inhibitor, it inhibited 50% of AChE activity at concentrations of 3.7 ± 0.3 ug/mL. Geissoschizine methyl ether protects neurons from oxidative toxicity by shifting energy metabolism from mitochondrial respiration to glycolysis. Geissoschizine methyl ether has vasorelaxant effect, which is composed of two different mechanisms: endothelial dependency with nitric oxide and endothelial independency with voltage-dependent Ca(2+)-channel blocking. |
| CFN89443 | 3'-Methoxydaidzin 3'-Methoxydaidzin has antioxidation activity, it may be a potential neuroprotective substance in Gegen Qinlian decoction. |
| CFN89438 | 1-O-Acetylbritannilactone 1-O-Acetylbritannilactone has anticancer activity, it suppresses angiogenesis and lung cancer cell growth possibly via regulating the VEGFR-Src-FAK signaling, it also can combine with gemcitabine elicits a potent apoptosis of lung cancer cell. 1-O-Acetylbritannilactone may serve as a novel therapeutic intervention for various cardiovascular diseases, including chronic ischemia, by regulating VEGF signaling and modulating angiogenesis; it is a potent inhibitor of LPS-stimulated VSMC inflammatory responses through blockade of NF-kappaB activity and inhibition of inflammatory gene COX-2 expression. 1-O-Acetylbritannilactone may act as potent natural skin-lightening agents, it exhibits anti-melanogenic activity by suppression of tyrosinase expression via ERK and Akt signaling. |
| CFN89436 | Axinysone B Axinysone B is a natiral product from the metabolites of the mushroom Anthracophyllum sp. BCC18695. |
| CFN89431 | (-)-Isolariciresinol 9'-O-glucoside Reference standards. |
| CFN89430 | Dehydrodiconiferyl alcohol 4-O-beta-D-glucopyranoside Dehydrodiconiferyl alcohol 4-O-beta-D-glucopyranoside is a natural product from Ligusticopsis wallichiana (DC) Pimenov & Kljuykov. |
| CFN89426 | 11-Anhydro-16-oxoalisol A Reference standards. |
| CFN89421 | Viscumneoside III Viscumneoside III demonstrates high tyrosinase inhibition, it can be utilized in skin whitening cosmetics. |
| CFN89419 | Debilon Debilon shows cytotoxic activity against P-388 cells. |
| CFN89408 | Glycycoumarin Glycycoumarin is an estrogen agonist, it shows moderate inhibitory effects against CYP1A2 and CYP2B6. Glycycoumarin has anti-liver cancer, neuroprotective, antioxidant and anti-inflammatory activities. Glycycoumarin has anti-hepatitis C virus (HCV) activity, with the IC(50) value of 8.8, ug/mL. Glycycoumarin has an inhibitory effect on smooth muscle contraction induced by various types of stimulants through the inhibition of PDEs, especially isozyme 3, followed by the accumulation of intracellular cAMP; it also can inhibit hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress/GSK-3-mediated mitochondrial pathway. |
| CFN89404 | Glycyrin Glycyrin, one of the main PPAR-gamma ligands of licorice, can significantly decrease the blood glucose levels of genetically diabetic KK-A(y) mice. Glycyrin exhibits anti-BsFtsZ GTPase activities, at levels comparable to that of the synthetic FtsZ inhibitor, Zantrin Z3. Glycyrin has anti-hepatitis C virus (HCV) activity with the IC(50) value of 7.2 ug/mL; it shows antibacterial activity against upper airway respiratory tract bacteria such as Streptococcus pyogenes, Haemophilus influenzae and Moraxella catarrhalis; it also possesses weaker anti-Helicobacter pylori activity, it may be a useful chemopreventive agent for peptic ulcer or gastric cancer in H. pylori-infected individuals. |
| CFN89389 | 7-Xylosyl-10-deacetyltaxol B |
| CFN89385 | 7-Xylosyl-10-deacetyltaxol C 7-Xylosyl-10-deacetyltaxol C is a natural product from Taxus wallichiana Zucc. |
| CFN89340 | Bruceine E Bruceine E exhibits significant blood glucose concentration reduction activity, it might act as an insulin secretagogue. |
| CFN89332 | Isohomoarbutin Isohomoarbutin is a natural product from Pyrola rotundifolia. |
| CFN89328 | Aristola-1(10),8-dien-2-one Reference standards. |
| CFN89307 | 2,6,4'-Trihydroxy-4-methoxybenzophenone 2,6,4'-Trihydroxy-4-methoxybenzophenone shows weak inhibitory activity of testosterone 5alpha-reductase, it also shows significant inhibition of pancreatic lipase activity. 2,6,4'-Trihydroxy-4-methoxybenzophenone has neurotrophic activity, it induced neurite outgrowth in PC-12 cells at concentration of 50 microg/ml. 2,6,4′-Trihydroxy-4-methoxybenzophenone exhibits low cytotoxic effect against HeLa and 3T3 cell lines with IC50 values of 132 ug/ml and 158 ug/ml, repectively. It also shows antioxidant activity on DPPH with IC50 of 10.57 ug/mL. |
| CFN89301 | Matairesinoside Matairesinoside is a natural product from Styrax japonica. |
| CFN89297 | Nyasol Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory properties by inhibiting iNOS expression; it also has antifungal activity, it is significantly effective in suppressing the Phytophthora blight on pepper plants. (-)-Nyasol exhibits the half maximal inhibitory concentration (IC50) value of 17.6 uM against D-glycero-α-D-manno-heptose-1-phosphate guanylyltransferase (HddC). (+)-Nyasol has antiprotozoal activity, it potently inhibits the growth of Leishmania major promastigotes, the IC50 being 12 microM, and moderately inhibits Plasmodium falciparum schizonts with the IC50 49 microM. |
| CFN89281 | 4'-O-Methylnyasol 4'-O-Methylnyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. |
| CFN89280 | Kobusin Kobusin, a Calmodulin inhibitor, shows mild antiplasmodial,anti-inflammatory, and cytotoxic activities; it may be beneficial for the treatment of neuro-inflammatory diseases through the inhibition of iNOS expression and peroxynitrite scavenging potential. Kobusin can mildly reduce gastrointestinal motility in mice, it activates CFTR and CaCCgie chloride channel activities in mouse colonic epithelia and shows inhibitory effects toward ANO1/CaCC-mediated short-circuit currents in ANO1/CaCC-expressing FRT cells. |
| CFN89274 | Olivil 4'-O-glucoside Olivil 4'-O-glucoside is a natural product from Gentianella acuta. |
| CFN89254 | Diversoside Diversoside is a natural product from Aster subspicatus. |
| CFN89231 | ar-Turmerone ar-Turmerone could be used as a low cost botanical insecticide for integrated management of cabbage looper in vegetable production. ar-Turmerone also shows larvicidal and biting deterrent activity against Aedes aegypti and Anopheles quadrimaculatus (Culicidae: Diptera). ar-Turmerone may have notable antibacterial activity to Bacillus cereus and Staphylococcus aureus, antifungal activity to Aspergillus niger, and cytotoxic activity to Hs 578T (breast tumor) and PC-3 (prostate tumor) cells. ar-Turmerone displays neuroprotective, and anticonvulsant properties, it exerts potent anti-inflammatory effects via suppression of the inflammatory cytokines IFN-γ and IL-2. |
| CFN89228 | 6-(4-Hydroxy-3-methylphenyl)-2-methylhept-2-en-4-one Reference standards. |
| CFN89177 | Chloranthalactone E Chloranthalactone E is a natural product from Chloranthus serratus. |
| CFN89146 | Nudiposide Nudiposide has significant neuroprotective activities against glutamate-injured neurotoxicity in HT22 cells. It also exhibits protective effect against sepsis in a mouse model and can decrease the plasma levels of TNF-α, IL-10 and ALT activity. |
| CFN89144 | Arjunglucoside II Arjunglucoside II exhibits a moderate free radical scavenging activity. |
| CFN89113 | 2-Hydroxy-3-methoxybenzoic acid glucose ester 2-Hydroxy-3-methoxybenzoic acid glucose ester shows a potent antagonistic activity against platelet activating factor (PAF), it can prevent the mice from the PAF-induced death at a dose of 300 micrograms/mouse. |
| CFN89067 | Angeloylgomisin O Angeloylgomisin O is a nartural product from Schisandra chinensis. |
