Natural Products
| Catalog No. | Information |
| CFN97963 | Citropten Citropten and valproic acid show antiproliferative effects against A2058 human melanoma cells. |
| CFN90597 | Tracheloside Tracheloside significantly decreases the activity of alkaline phosphatase (AP), an estrogen-inducible marker enzyme, with an IC(50) value of 0.31 microg/ml, a level of inhibition comparable to that of tamoxifen (IC(50) = 0.43 microg/ml). |
| CFN90598 | Trachelogenin Trachelogenin has antiproliferative effect, the mechanism is related to affect the phosphorylation of key proteins such as β-Catenin, c-Myc and GSK3 in the β-Catenin signaling pathway in a concentration-dependent manner. |
| CFN92887 | Euphorbia factor L9 Reference standards. |
| CFN92886 | Euphorbia factor L8 Reference standards. |
| CFN92885 | Euphorbia factor L7a Reference standards. |
| CFN92883 | Euphorbia factor L1 Euphorbia factor L1 inhibits osteoclastogenesis and induces osteoclast apoptosis, it can enhance the ATP hydrolysis activity of ABCB1 stimulated by verapamil. Euphorbia factor L1 inhibits the efflux of ABCB1 in KBv200 and MCF-7/adr cells, does not downregulate their expression either in mRNA or protein level. |
| CFN92882 | Ebracteolata cpd B |
| CFN92855 | 4',7-Dihydroxyflavone 4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2. |
| CFN92838 | Poricoic acid A(F) Poricoic acid A(F) shows anti-inflammatory activity. It is a potential whitening active ingredient, it exhibits good inhibitory effects on the activities of monophenolase and diphenolase in mushroom tyrosinase, as well as a certain inhibitory effect on tyrosinase in B16 cells. |
| CFN92837 | Dehydrotumulosic acid Dehydrotumulosic acid shows anti-inflammatory activity. |
| CFN92836 | Peroxydehydrotumulosic acid 5alpha,8alpha-Peroxydehydrotumulosic acid exhibits inhibitory effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells. |
| CFN92826 | Cis-N-Feruloyltyramine Cis-N-Feruloyltyramine shows cytotoxicity against the P-388 cancer cell line. N-cis-Feruloyltyramine and N-trans-Feruloyltyramine are the inhibitors of in vitro prostaglandin (PG) synthesis. |
| CFN97865 | Eriodictyol-7-O-glucoside Eriodictyol-7-O-glucoside and epicatechin appears to be responsible for the antioxidant activity of pistachio skin.Eriodictyol-7-O-glucoside has protective effect on cisplatin-induced toxicity was investigated in a human renal mesangial cell line, HRMC; it also can activate Nrf2/ARE signaling, directly associated with its neuroprotection against oxidative stress-induced ischemic; suggests that targeting the Nrf2/ARE pathway may be a promising approach for therapeutic intervention in stroke. |
| CFN92818 | Ginsenoside Rk2 Ginsenoside Rk1 has anti-tumor, and anti-platelet aggregation activities. Ginsenoside Rk1 can strongly inhibit permeability induced by VEGF, advance glycation end-product, thrombin, or histamine in human retinal endothelial cells, it reduces the vessel leakiness of retina in a diabetic mouse model; this anti-permeability activity of Rk1 is correlated with enhanced stability and positioning of tight junction proteins at the boundary between cells; Rk1 induces phosphorylation of myosin light chain and cortactin, which are critical regulators for the formation of the cortical actin ring structure and endothelial barrier. |
| CFN92810 | Dihydrosanguinarine Dihydrosanguinarine has antifungal and anticancer activity.Dihydrosanguinarine at concentrations from 5 microM induced primarily necrosis, whereas apoptosis occurred at 10 microM and above. Dihydrosanguinarine has potential application in the therapy of serious infection caused by I. multifiliis. |
| CFN92806 | 3,4'-Di-O-methylellagic acid Reference standards. |
| CFN92798 | Panaxydiol Panaxydiol can inhibit rat liver cholesterol acyltransferase (ACAT) with IC50 values of 45 microM. |
| CFN92792 | Curculigoside C Standard reference |
| CFN90557 | Oxypeucedanin hydrate Oxypeucedanin hydrate is an antimutagenic agent, it has antioxidant activity, and exhibits carbohydrate metabolizing enzymes inhibitory effect. |
| CFN92764 | Tilianin Tilianin has anti-inflammatory, antiatherogenic, antihypertensive and vasorelaxant activities, mediates relaxation and antihypertension mainly by an endothelium-dependent manner, probably due to NO release, and also through an endothelium-independent pathway by opening K+ channels. Tilianin inhibits the tumor necrotic factor-K (TNF-K)-induced expression of VCAM-1 by 74% and reduces TNF-K-induced activation of nuclear factor-UB in cultured human umbilical vein endothelial cells (HUVECs). |
| CFN92755 | Ajuganipponin A Reference standards. |
| CFN92752 | Ajugacumbin A Reference standards. |
| CFN92750 | Loliolid Loliolid is a germination inhibitor, and a repellent for ants (Atta cephalotes).It has cytostatic activity against carcnoma and leukaemia cells. |
| CFN92744 | Glycosmisic acid Glycosmisic acid is a natural product from Nauclea officinalis. |
| CFN92743 | 3-Epidehydrotumulosic acid 3-Epidehydrotumulosic acid has inhibitory activity against AAPH-induced lysis of red blood cells. |
| CFN92742 | Dehydropachymic acid Dehydropachymic acid shows antiinflammatory activity. |
| CFN92741 | 6alpha-Hydroxypolyporenic acid C 6alpha-Hydroxypolyporenic acid C is a natural product from Wolfiporia cocos (Schw.) Ryv. |
| CFN92740 | Dehydroeburicoic acid Dehydroeburicoic acid induces necrotic cell death that involves Ca(2+) overload, mitochondrial dysfunction, and calpain activation in human glioblastomas. Dehydroeburicoic acid and Eburicoic acid have antioxidant and anti-inflammatory activities by the decrease of inflammatory cytokines and an increase of antioxidant enzyme activity, can protect the liver from CCl4-induced hepatic damage. |
| CFN92739 | Polyporenic acid C Polyporenic acid C shows inhibitory activity against human collagenase. Polyporenic acid C induces apoptosis through the death receptor-mediated apoptotic pathway where the activation of caspase-8 leads to the direct cleavage of execution caspases without the involvement of the mitochondria. |
| CFN92738 | 3-Epidehydropachymic acid Reference standards. |
| CFN92719 | Gomisin F Standard reference |
| CFN92716 | Gomisin S Reference standards. |
| CFN92715 | Schisantherin C Schisantherin A, B, C, and D show good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis. |
| CFN92712 | Marmesin Marmesin has hepatoprotective potential; it also has cytotoxic with a 50% lethal dose of less than 0.5 micrograms/ml, is not as mutagenic or potentially carcinogenic as are AFB1, imperatorin, or MOP with BL activation. |
| CFN92706 | 6-Methoxyluteolin 6-Methoxyluteolin has antioxidant activity, it is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain. |
| CFN92703 | 3-Hydroxybakuchiol 3-Hydroxybakuchiol exerts cytotoxic and anti-proliferative effects on the TA3/Ha mouse mammary adenocarcinoma cell line and induces a decrease in the mitochondrial transmembrane potential, the activation of caspase-3, the opening of the mitochondrial permeability transport pore (MPTP) and nuclear DNA fragmentation.3-Hydroxybakuchiol has antitumor activity resulting from interactions with the ETC, a system that is already deficient in cancer cells. |
| CFN92693 | Coelonin Coelonin shows moderate cytotoxic activity against HepG2 cells. |
| CFN92685 | 1,7-Diphenyl-4-hepten-3-one 1,7-Diphenyl-4-hepten-3-one has feeding deterrent activities against Tribolium castaneum. |
| CFN92656 | Kawain Kavain has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels. Kawain is advanced glycation endproduct inhibitors, can increase the mean life span of Caenorhabditis elegans exposed to high glucose. |
| CFN92643 | Ginsenoside Rg5 Ginsenoside Rg5 plays a novel role as an IGF-1R agonist, promoting therapeutic angiogenesis and improving hypertension without adverse effects in the vasculature, it can ameliorate lung inflammation possibly by inhibiting the binding of LPS to toll-like receptor (TLR)-4 on macrophages. Ginsenoside Rg5 blocks cell cycle of SK-HEP-1 cells at the Gl/S transition phase by down-regulating cyclin E-dependent kinase activity and that the down-regulation of cyclin E-dependent kinase activity is caused mainly by induced CDK2 inhibitor, p21Cip/WAF1 and decreased levels of cyclin E. |
| CFN92616 | Zederone Zederone has anti-bacterial activity,it inhibits gram-positive bacteria activity. Zederone induces hepatotoxicity implicated the induction of Cyps, which leads to the formation of biological reactive metabolites and that cause the oxidative stress and liver cell injuries. |
| CFN92614 | Curcumenol Curcumenol possesses a variety of health and medicinal values which includes neuroprotection, anti-inflammatory, anti-tumor and hepatoprotective activities. It inhibits NF-κB activation by suppressing the nuclear translocation of the NF-κB p65 subunit and blocking IκBα phosphorylation and degradation. |
| CFN92603 | Rubinaphthin A Rubinaphthin A is a natural product from Rubia cordifolia. |
| CFN92601 | Britannilactone Britannilactone significantly reduces melanin production in a dose-dependent manner with the IC50 value of 15.5 uM. |
| CFN92600 | 1beta-Hydroxyalantolactone 1beta-Hydroxyalantolactone has protective effect against AD-like skin inflammation, can as a potential therapeutic agent for AD. |
| CFN92599 | Ivangustin Ivangustin exhibits remarkable cytotoxicity against HEp2, SGC-7901 and HCT116 human cancer cell lines. |
| CFN92594 | Ginsenoside Rh4 Ginsenoside Rh4 is a rare saponin obtained from Panax notoginseng. Ginsenoside Rh4 activates Bax, caspase 3, caspase 8, and caspase 9. Ginsenoside Rh4 also induces autophagy. Ginsenoside Rh4 could be safely used as adjuvant with low or non-haemolytic effect; it has cytotoxic activity and its aglycone against cancer cell lines. |
| CFN92593 | Ginsenoside Rk3 Ginsenoside Rk3 is often used as a major ingredient of the compound preparation for ischemic heart diseases, it could have a role in treating inflammatory diseases. Ginsenoside Rk3 significantly inhibits TNF-α-induced NF-κB transcriptional activity, with an IC50 of 14.24±1.30 μM in HepG2 cells. |
| CFN92574 | 3-Oxopomolic acid Reference standards. |
