Natural Products
| Catalog No. | Information |
| CFN96395 | Zanthobungeanine Zanthobungeanine has anti-inflammatory activity, it shows moderate NO production inhibitory activity with an IC50 value of 37.26 mg /L.It shows obviously inhibitoryactivity to platelet aggregation caused by platelet-activating factor (PAF). Zanthobungeanine shows the inhibitory action on the development of A549 cell only in high concentration and has no antipersonnel effect on A549 cell. |
| CFN96389 | Licoricidin Licoricidin, is a potent anti-metastatic agent, which can markedly inhibit the metastatic and invasive capacity of malignant prostate cancer cells. Licoricidin and licorisoflavan A are effective in inhibiting the growth of all three bacterial species(Porphyromonas gingivalis, Prevotella intermedia and Solobacterium moorei), with minimal inhibitory concentrations in the range of 2-80 ug /ml, they have a potential for reducing bacterial volatile sulfur compounds (VSCs) production and therefore for controlling halitosis; they also have potential for the development of novel host-modulating strategies for the treatment of cytokine and/or MMP-mediated disorders such as periodontitis. Licoricidin may be considered as an active ingredient in new topically applied anti-ageing formulations, it blocks UVA-induced photoaging via ROS scavenging,this activity converges to limit the activity of MMP-1. |
| CFN96362 | Robustine Robustine may have anti-inflammatory activity, it exhibits inhibition (IC 50 < or = 18.19 microM) of superoxide anion generation by human neutrophils in response to formyl- l-methionyl- l-leucyl- l-phenylalanine/cytochalasin B (FMLP/CB). |
| CFN96355 | Splendoside Standard reference |
| CFN96346 | Ligucyperonol Ligucyperonol exhibits significant activities on protecting muscle cells from mild to moderate oxidative stress. |
| CFN96306 | Dehydroborapetoside B Reference standards. |
| CFN96298 | Borapetoside B Standard reference |
| CFN96291 | 5-Hydroxy-1,7-bis(4-hydroxyphenyl)heptan-3-yl acetate Reference standards. |
| CFN96275 | 1-(3,4-Dihydroxyphenyl)-7-(4-hydroxyphenyl)heptane-3,5-diyl diacetate Reference standards. |
| CFN96274 | Borapetoside E Borapetoside E has anti-hyperglycemic activity, it can significantly reduce serum glucose levels at dose-dependent manners in alloxan-induced hyperglycemic mice and db/db type 2 diabetic mice. |
| CFN96266 | Eudesmin Eudesmin shows antiinflammatory, neuritogenic, anticonvulsant and sedative effects, the mechanism of eudesmin may be related to up-regulation of GABAA and GAD65 expressions, and anti-apoptosis of neuron the in brain.50 microM (+)-eudesmin can induce neurite outgrowth and enhance nerve growth factor (NGF)-mediated neurite outgrowth from PC12 cells by stimulating up-stream MAPK, PKC and PKA pathways. |
| CFN95009 | 6-Hydroxywogonin |
| CFN94832 | Raddeanoside R8 Raddeanoside R8 is a natural product from Anemone raddeana Regel. |
| CFN95008 | Isonemerosin Reference standards. |
| CFN95007 | 8,8''-Bibaicalein 8,8''-Bibaicalein is a natural product from Scutellaria baicalensis. |
| CFN94466 | Quercetin-3-O-glucose-6''-acetate Quercetin-3-O-glucose-6''-acetate is a NADPH oxidase inhibitor, it has antioxidant capacity. |
| CFN90868 | Picroside IV Kutkoside is a mixture of iridoid glycosides namely, picroside II, Picroside IV and 6-ferulloylcatalpol, it may have antinociceptive and anti-inflammatory effects. |
| CFN90864 | meso-Hannokinol meso-Hannokinol and (+)-hannokinol can significantly inhibit lipopolysaccharide-induced nitric oxide production in BV2 microglial cells at concentrations ranging from 1 uM to 100 uM. |
| CFN90861 | Continentalic acid Continentalic acid and kaurenoic acid are quality control markers in Aralia continentalis. Continentalic acid has anti-inflammatory, anti-cancer, and anti-bacterial activities, it shows moderate cytotoxicity against A-549 (lung), THP-1 (leukemia) and MCF-7 (breast) cell lines; it has minimum inhibitory concentrations (MICs) of approximately 8-16 microg/mL against S. aureus, including the MSSA and MRSA standard strains. |
| CFN90859 | Notoginsenoside Ft1 Notoginsenoside Ft1 is a novel stimulator of angiogenesis, it stimulates angiogenesis via HIF-1α-mediated VEGF expression, with PI3K/AKT and Raf/MEK/ERK signaling cascades concurrently participating in the process; it has the potential therapeutic effect on human neuroblastoma, it can arrest the proliferation and elicited the apoptosis of SH-SY5Y cells possibly via p38 MAPK and ERK1/2 pathways.Notoginsenoside Ft1 activates both glucocorticoid and estrogen receptors to induce endothelium-dependent, nitric oxide-mediated relaxations in rat mesenteric arteries. Notoginsenoside Ft1 also provides a great potential application of it in clinics for patients with diabetic foot ulcers, it may accelerate diabetic wound healing by orchestrating multiple processes, including promoting fibroblast proliferation, enhancing angiogenesis, and attenuating inflammatory response. |
| CFN96255 | Lupeolic acid Lupeolic acid has anti-inflammatory activity. |
| CFN96248 | Hannokinol (+)-Hannokinol and MESO-hannokinol can significantly inhibit lipopolysaccharide-induced nitric oxide production in BV2 microglial cells at concentrations ranging from 1 microM to 100 microM. |
| CFN96238 | Juglanin Juglanin has anti-tumor, antioxidant,and hepatoprotective activities. Juglanin shows protective effects on fructose-induced hepatitis by inhibiting inflammation and apoptosis through TLR4 and JAK2/STAT3 signaling pathways in fructose-fed rats. Juglanin can lead to G2/M phase arrest, induce apoptosis as well as autophagy through the ROS/JNK signaling pathway in human breast cancer cells |
| CFN90858 | 4,5-Di-O-caffeoylquinic acid methyl ester 4,5-Di-O-caffeoylquinic acid methyl ester shows high efficiency and low toxicity with antivirus activity against RSV. |
| CFN90857 | 3,5-Di-O-caffeoylquinic acid methyl ester 3,5-Di-O-caffeoylquinic acid methyl ester exhibits potent inhibitory activities against the formation of advanced glycation end products (AGEs); it exhibits cytotoxicity actions against human cervix carcinoma HeLa cells. 3,5-Di-O-caffeoylquinic acid methyl ester shows high efficiency and low toxicity with antivirus activity against RSV. |
| CFN90856 | 3,4-Di-O-caffeoylquinic acid methyl ester 3,4-Di-O-caffeoylquinic acid methyl ester shows high efficiency and low toxicity with antivirus activity against RSV; it exhibits cytotoxicity actions against human cervix carcinoma HeLa cells. |
| CFN96224 | Kaempferol 7-O-rhamnoside Kaempferol 7-O-rhamnoside is a natural product from Maytenus hookeri. |
| CFN96221 | 3,7-Di-O-methylquercetin 3,7-Di-O-methylquercetin shows α-glucosidase inhibition. |
| CFN90855 | Quercetagetin-7-O-glucoside Quercetagetin-7-O-glucoside, a potent inhibitor of beta-glucuronidase and lysozyme release, shows anti-inflammatory activity, can significantly inhibit arachidonic acid release from membranes. |
| CFN90839 | Isomucronulatol Isoliquiritigenin and liquiritigenin exhibit significant inhibitory effects on LPS-induced IL-6 and IL-12 p40 production, with IC 50 values ranging from 2.7 to 6.102uM, isoliquiritigenin also shows a moderate inhibitory effect on LPS-stimulated production of TNF-α with an IC 50 value of 20.102 uM, they have potential anti-inflammatory effects. Isomucronulatol exhibits noticeable ABTS+ scavenging activity, it exhibits moderate inhibition against butyrylcholinesterase. |
| CFN90838 | Methylnissolin Methylnissolin is a natural product from A. membranaceus. |
| CFN92889 | 5-O-Feruloylquinic acid 5-O-feruloylquinic acid is a potent Sirt1 agonist, it is a potential lead compound that can be further tested in drug development process for diseases associated with aging. |
| CFN95006 | cis-Mulberroside A cis-Mulberroside A shows high analgesic and anti-inflammatory activities, it can protect mice against ethanol-induced hepatic damage. |
| CFN90831 | Galloylpaeoniflorin Galloylpaeoniflorin exhibits anticomplement effects, it reveals a more pronounced radical scavenging effect than a-tocopherol. Galloylpaeoniflorin can take part in improving blood circulation by inhibiting ether platelet aggregation and/or blood coagulation. Galloylpaeoniflorin exhibits good activity on acute lung injury. |
| CFN90830 | 3,3'-Di-O-methylellagic acid 4'-glucoside Reference standards. |
| CFN90829 | 20(21)-Dehydrolucidenic acid A 20(21)-dehydrolucidenic acid A is a natural product from Ganoderma lucidum. |
| CFN90827 | Rubrofusarin-6-O-beta-D-gentiobioside Rubrofusarin-6-O-beta-D-gentiobioside can significantly decrease the expression of TGF-beta1 and fibronectin and NF-kappaB DNA binding activity, suggests that it has potential as a preventive agent for advanced glycation end products-related diabetic complications. |
| CFN90826 | Cassiaside Cassiaside has significant hepato-protective effects against galactosamine damage, which is higher than that of silybin from Silybum marianum. Cassiaside demonstrates significant antimutagenic, and 1,1-diphenyl-2-picrylhydrazyl(DPPH) radical scavenging effects. Cassiaside and emodi show mixed-type inhibition against β-site amyloid precursor protein (APP) cleaving enzyme 1 (BACE1). |
| CFN95005 | Apterin Apterin has anti-inflammatory activity in vitro, it shows significantly inhibitory activity on nitric oxide production in RAW264.7 cells. |
| CFN95004 | Decuroside I Decuroside I shows weak inhibiting activity against the primary and secondary wave aggregation of human platelet. |
| CFN95003 | Pd-C-II Pd-C-II has anti-inflammation activity, it can inhibit TNF-α production and iNOS protein expression and inhibit COX-2 protein expression in LPS-stimulated RAW 264.7 cells. Pd-C-II inhibits anaphylactic mediator release from purified mast cells induced by concanavalin A with phosphatidylserine, the IC50 value of 79 microM. |
| CFN95002 | Decursitin D Decursitin D is a natural product from the roots of Peucedanum decursivum. |
| CFN95001 | Oroselol Oroselol, jatamansinol, nardostachysin, jatamansinone and nardosinone are Nardostachys jatamansi rhizome extract marker compounds. |
| CFN90819 | Mauritianin Mauritianin and (+)-syringaresinol as new topoisomerase I inhibitors. Mauritianin has statistically significant cytoprotective activity similar to that of silymarin, tested at 60 ug/mL. |
| CFN90818 | Semilicoisoflavone B Semilicoisoflavone B can inhibit sorbitol formation of rat lens incubated with a high concentration of glucose, indicates that it may be effective for preventing osmotic stress in hyperglycemia. |
| CFN90817 | Glycyrrhisoflavone Glycyrrhisoflavone is a tyrosinase inhibitor, it also shows inhibitory effects on monoamine oxidase. Glycybenzofuran shows significant protein tyrosine phosphatase-1B (PTP1B) inhibitory activity in vitro with the IC50 value of 25.5 microM. Glycyrrhisoflavone has anti-inflammatory effects, it has significant inhibitory effects against NO production on LPS-induced RAW 264.7 cell model. |
| CFN90816 | Licoisoflavone A Licoisoflavone A is a potential MRP inhibitor, it shows inhibitory effects on copper-induced protein oxidative modification of mice brain homogenate in vitro. |
| CFN90815 | Effusol Effusol can induce caspase-3-mediated cytotoxicity in HT22 cells. |
| CFN90814 | Dehydroeffusol Dehydroeffusol possesses anti-cancer, anxiolytic and sedative properties, it may antagonize the spasmogenic activity of various agents, and therefore, could be a promising agent in the treatment of spasms. Dehydroeffusol displays enhanced antimicrobial activities in light, its antimicrobial activities (minimum inhibitory concentrations) against methicillin-resistant and -sensitive Staphylococcus aureus and Candida albicans are increased 16 fold by irradiation with ultraviolet A (UVA). |
| CFN90813 | Juncusol Juncusol shows anxiolytic and sedative activities, it shows anxiolytic activity at dosages of 10 mg/kg; it can induce caspase-3-mediated cytotoxicity in HT22 cells. Juncusol has anti-microbial activity, it shows significant activity against MRSA strains. |
