Natural Products
| Catalog No. | Information |
| CFN92883 | Euphorbia factor L1 Euphorbia factor L1 inhibits osteoclastogenesis and induces osteoclast apoptosis, it can enhance the ATP hydrolysis activity of ABCB1 stimulated by verapamil. Euphorbia factor L1 inhibits the efflux of ABCB1 in KBv200 and MCF-7/adr cells, does not downregulate their expression either in mRNA or protein level. |
| CFN92882 | Ebracteolata cpd B |
| CFN92855 | 4',7-Dihydroxyflavone 4',7-Dihydroxyflavone can induce transcription of nodulation (nod) genes in Rhizobium meliloti. It has inhibitory activities against COX-2. |
| CFN92838 | Poricoic acid A(F) Poricoic acid A(F) shows anti-inflammatory activity. It is a potential whitening active ingredient, it exhibits good inhibitory effects on the activities of monophenolase and diphenolase in mushroom tyrosinase, as well as a certain inhibitory effect on tyrosinase in B16 cells. |
| CFN92837 | Dehydrotumulosic acid Dehydrotumulosic acid shows anti-inflammatory activity. |
| CFN92836 | Peroxydehydrotumulosic acid 5alpha,8alpha-Peroxydehydrotumulosic acid exhibits inhibitory effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells. |
| CFN92826 | Cis-N-Feruloyltyramine Cis-N-Feruloyltyramine shows cytotoxicity against the P-388 cancer cell line. N-cis-Feruloyltyramine and N-trans-Feruloyltyramine are the inhibitors of in vitro prostaglandin (PG) synthesis. |
| CFN97865 | Eriodictyol-7-O-glucoside Eriodictyol-7-O-glucoside and epicatechin appears to be responsible for the antioxidant activity of pistachio skin.Eriodictyol-7-O-glucoside has protective effect on cisplatin-induced toxicity was investigated in a human renal mesangial cell line, HRMC; it also can activate Nrf2/ARE signaling, directly associated with its neuroprotection against oxidative stress-induced ischemic; suggests that targeting the Nrf2/ARE pathway may be a promising approach for therapeutic intervention in stroke. |
| CFN92818 | Ginsenoside Rk2 Ginsenoside Rk1 has anti-tumor, and anti-platelet aggregation activities. Ginsenoside Rk1 can strongly inhibit permeability induced by VEGF, advance glycation end-product, thrombin, or histamine in human retinal endothelial cells, it reduces the vessel leakiness of retina in a diabetic mouse model; this anti-permeability activity of Rk1 is correlated with enhanced stability and positioning of tight junction proteins at the boundary between cells; Rk1 induces phosphorylation of myosin light chain and cortactin, which are critical regulators for the formation of the cortical actin ring structure and endothelial barrier. |
| CFN92810 | Dihydrosanguinarine Dihydrosanguinarine has antifungal and anticancer activity.Dihydrosanguinarine at concentrations from 5 microM induced primarily necrosis, whereas apoptosis occurred at 10 microM and above. Dihydrosanguinarine has potential application in the therapy of serious infection caused by I. multifiliis. |
| CFN92809 | Isosakuranin Isosakuranin is a product from Paliurus ramosissimus. |
| CFN92806 | 3,4'-Di-O-methylellagic acid Reference standards. |
| CFN92800 | Qianhucoumarin G Qianhucoumarin G is a natural product from Peucedanum praeruptorum. |
| CFN92799 | cis-Khellactone cis-Khellactone is a natural product from Angelica sinensis. |
| CFN92798 | Panaxydiol Panaxydiol can inhibit rat liver cholesterol acyltransferase (ACAT) with IC50 values of 45 microM. |
| CFN92792 | Curculigoside C Standard reference |
| CFN90557 | Oxypeucedanin hydrate Oxypeucedanin hydrate is an antimutagenic agent, it has antioxidant activity, and exhibits carbohydrate metabolizing enzymes inhibitory effect. |
| CFN92764 | Tilianin Tilianin has anti-inflammatory, antiatherogenic, antihypertensive and vasorelaxant activities, mediates relaxation and antihypertension mainly by an endothelium-dependent manner, probably due to NO release, and also through an endothelium-independent pathway by opening K+ channels. Tilianin inhibits the tumor necrotic factor-K (TNF-K)-induced expression of VCAM-1 by 74% and reduces TNF-K-induced activation of nuclear factor-UB in cultured human umbilical vein endothelial cells (HUVECs). |
| CFN92757 | Ajugamarin L2 (Ajugacumbin B) Reference standards. |
| CFN92755 | Ajuganipponin A Reference standards. |
| CFN92752 | Ajugacumbin A Reference standards. |
| CFN92750 | Loliolid Loliolid is a germination inhibitor, and a repellent for ants (Atta cephalotes).It has cytostatic activity against carcnoma and leukaemia cells. |
| CFN92744 | Glycosmisic acid Glycosmisic acid is a natural product from Nauclea officinalis. |
| CFN92743 | 3-Epidehydrotumulosic acid 3-Epidehydrotumulosic acid has inhibitory activity against AAPH-induced lysis of red blood cells. |
| CFN92742 | Dehydropachymic acid Dehydropachymic acid shows antiinflammatory activity. |
| CFN92741 | 6alpha-Hydroxypolyporenic acid C 6alpha-Hydroxypolyporenic acid C is a natural product from Wolfiporia cocos (Schw.) Ryv. |
| CFN92740 | Dehydroeburicoic acid Dehydroeburicoic acid induces necrotic cell death that involves Ca(2+) overload, mitochondrial dysfunction, and calpain activation in human glioblastomas. Dehydroeburicoic acid and Eburicoic acid have antioxidant and anti-inflammatory activities by the decrease of inflammatory cytokines and an increase of antioxidant enzyme activity, can protect the liver from CCl4-induced hepatic damage. |
| CFN92739 | Polyporenic acid C Polyporenic acid C shows inhibitory activity against human collagenase. Polyporenic acid C induces apoptosis through the death receptor-mediated apoptotic pathway where the activation of caspase-8 leads to the direct cleavage of execution caspases without the involvement of the mitochondria. |
| CFN92738 | 3-Epidehydropachymic acid Reference standards. |
| CFN92719 | Gomisin F Standard reference |
| CFN92716 | Gomisin S Reference standards. |
| CFN92715 | Schisantherin C Schisantherin A, B, C, and D show good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis. |
| CFN92712 | Marmesin Marmesin has hepatoprotective potential; it also has cytotoxic with a 50% lethal dose of less than 0.5 micrograms/ml, is not as mutagenic or potentially carcinogenic as are AFB1, imperatorin, or MOP with BL activation. |
| CFN92709 | Qianhucoumarin A Standard reference |
| CFN92706 | 6-Methoxyluteolin 6-Methoxyluteolin has antioxidant activity, it is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain. |
| CFN92703 | 3-Hydroxybakuchiol 3-Hydroxybakuchiol exerts cytotoxic and anti-proliferative effects on the TA3/Ha mouse mammary adenocarcinoma cell line and induces a decrease in the mitochondrial transmembrane potential, the activation of caspase-3, the opening of the mitochondrial permeability transport pore (MPTP) and nuclear DNA fragmentation.3-Hydroxybakuchiol has antitumor activity resulting from interactions with the ETC, a system that is already deficient in cancer cells. |
| CFN92702 | 12-Hydroxyisobakuchiol Standard reference |
| CFN92693 | Coelonin Coelonin shows moderate cytotoxic activity against HepG2 cells. |
| CFN92685 | 1,7-Diphenyl-4-hepten-3-one 1,7-Diphenyl-4-hepten-3-one has feeding deterrent activities against Tribolium castaneum. |
| CFN92684 | (R)-5-Hydroxy-1,7-diphenyl-3-heptanone Reference standards. |
| CFN92656 | Kawain Kavain has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels. Kawain is advanced glycation endproduct inhibitors, can increase the mean life span of Caenorhabditis elegans exposed to high glucose. |
| CFN92652 | Zedoarondiol Zedoarondiol has anti-inflammatory activity, inhibits iNOS, COX-2, and pro-inflammatory cytokine expressions by suppressing the phosphorylations of IKK and MAPKs, and by subsequently inactivating the NF-kappaB pathway. It dose-dependently inhibits LPS-stimulated nitric oxide (NO), prostaglandin E(2) (PGE(2)), tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), and interleukin-1beta (IL-1beta) productions in RAW 264.7 macrophage and in mouse peritoneal macrophage cells. |
| CFN92648 | 13-Hydroxygermacrone 13-Hydroxygermacrone inhibits UVB-induced upregulation of the mRNA and protein expression levels of MMP-1, MMP-2, and MMP-3 in human keratinocytes (HaCaT). 13-Hydroxygermacrone shows a protective effect against D-GalN/tumor necrosis factor-alpha-induced liver injury in mice at a dose of 50 mg/kg p.o. |
| CFN92647 | Procurcumenol Procurcumenol is an inhibitor of Nitric Oxide. Procurcumenol and epicurcumenol have inhibitory effects on release of tumor necrosis factor-a (TNF-a). |
| CFN92643 | Ginsenoside Rg5 Ginsenoside Rg5 plays a novel role as an IGF-1R agonist, promoting therapeutic angiogenesis and improving hypertension without adverse effects in the vasculature, it can ameliorate lung inflammation possibly by inhibiting the binding of LPS to toll-like receptor (TLR)-4 on macrophages. Ginsenoside Rg5 blocks cell cycle of SK-HEP-1 cells at the Gl/S transition phase by down-regulating cyclin E-dependent kinase activity and that the down-regulation of cyclin E-dependent kinase activity is caused mainly by induced CDK2 inhibitor, p21Cip/WAF1 and decreased levels of cyclin E. |
| CFN92616 | Zederone Zederone has anti-bacterial activity,it inhibits gram-positive bacteria activity. Zederone induces hepatotoxicity implicated the induction of Cyps, which leads to the formation of biological reactive metabolites and that cause the oxidative stress and liver cell injuries. |
| CFN92614 | Curcumenol Curcumenol possesses a variety of health and medicinal values which includes neuroprotection, anti-inflammatory, anti-tumor and hepatoprotective activities. It inhibits NF-κB activation by suppressing the nuclear translocation of the NF-κB p65 subunit and blocking IκBα phosphorylation and degradation. |
| CFN92603 | Rubinaphthin A Rubinaphthin A is a natural product from Rubia cordifolia. |
| CFN92601 | Britannilactone Britannilactone significantly reduces melanin production in a dose-dependent manner with the IC50 value of 15.5 uM. |
| CFN92600 | 1beta-Hydroxyalantolactone 1beta-Hydroxyalantolactone has protective effect against AD-like skin inflammation, can as a potential therapeutic agent for AD. |
