Natural Products
| Catalog No. | Information |
| CFN91948 | 8beta,9alpha-Dihydroxylindan-4(5),7(11)-dien-8alpha,12-olide Reference standards. |
| CFN91967 | 6alpha-Chloro-5beta-hydroxywithaferin A Reference standards. |
| CFN91969 | 2,3-Didehydrosomnifericin Reference standards. |
| CFN91972 | (-)-Dihydroguaiaretic acid Reference standards. |
| CFN91988 | Isoshinanolone Isoshinanolone shows excellent toxicity with LC(50) values of 1.26 microg/mL. trans-Isoshinanolone shows cytotoxicity against MDA-MB-231 breast cancer cells. |
| CFN91999 | Arnicolide D Arnicolide D exerts strong cytotoxic activity on the human colon carcinoma HT-29 cell line. |
| CFN92996 | Ganoderic acid X Ganoderic acid X is a potential Mdm2 inhibitor(K(i) = 16nM). It is a potential anticancer drug, inhibits topoisomerases and induces apoptosis of cancer cells. |
| CFN92994 | Lucidenic acid SP1 (Lucidenic acid LM1) Reference standards. |
| CFN92991 | Ganoderenic acid B Ganoderenic acid B can enhance the cytotoxicity of chemotherapeutics towards ABCB1-mediated MDR cancer cells via inhibition of the transport function of ABCB1. |
| CFN92988 | Angelol G Angelol G is a natural product from Angelica sinensis. |
| CFN92966 | Tamgermanetin Tamgermanetin demonstrates potential cytotoxic effect against three different tumor cell lines, namely liver (Huh-7), breast (MCF-7) and prostate (PC-3). |
| CFN92961 | Curculigoside B Curculigoside B shows antioxidative and antiosteoporotic activities, it can decrease area of bone resorption pit, osteoclastic formation and TRAP activity. |
| CFN92950 | 5-O-Caffeoylshikimic acid 5-O-Caffeoylshikimic acid shows anti-oxidative activity; it also shows anti-inflammatory activity, the underlying mechanism was associated with downregulation of nuclear factor-κB. 5-O-Caffeoylshikimic acid can remarkably inhibit the macrophage migration and adhesion. It also shows moderate MDR reversal activity. |
| CFN92940 | Physalin A Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling, it inhibits androgen-independent prostate cancer cell growth through activation of cell apoptosis and downregulation of androgen receptor expression. Physalin A induces apoptosis via p53-Noxa-mediated ROS generation, and autophagy plays a protective role against apoptosis through p38-NF-κB survival pathway in A375-S2 cells. |
| CFN92939 | Physalin D Physalin D shows antimalarial activity; it also exhibits a minimum inhibitory concentration value (MIC) against Mycobacterium tuberculosis H(37)Rv strain of 32 microg/mL. Physalin D displays considerable cytotoxicity against several cancer cell lines. It presents antinociceptive properties associated with central. |
| CFN92936 | Isophysalin A Isophysalin A exhibits anti-inflammatory activitiy, it exhibits conjugating abilities with glutathione and also shows significant nitric oxide (NO) production inhibiting activities. |
| CFN92916 | Silybin B Silybin B and silybin A are potent inhibitors of both raloxifene 4'- and 6-glucuronidation in all enzyme systems; they show strong effects on cell growth inhibition and apoptosis induction in human chronic myeloid leukemia K562 cells. Silybin B exhibits 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity. |
| CFN92915 | Licoricesaponin G2 Licoricesaponin G2 has the anti-inflammatory effects as NF-κB inhibitors, it has anti-HIV activity via significantly interacted with R15K. |
| CFN90984 | Rebaudioside G Reference standards. |
| CFN90965 | Isoscoparin Isoscoparin has antioxidant, and anti-adipogenic effects, it may be a potential therapeutic agent for the prevention and treatment of obesity. Isoscoparin can significantly inhibit the production of both NO and TNF-α at a concentration of 2.0 uM. |
| CFN90958 | Sophorabioside Sophorabioside is a natural product from Sophora japonica. |
| CFN90953 | Genistein 7,4'-di-O-beta-D-glucopyranoside Genistein 7,4'-di-O-beta-D-glucopyranoside shows significant estrogenic proliferative effect in MCF-7 cell in sub-cytotoxic concentration range. |
| CFN90949 | Epimagnolin A Epimagnolin A affects the transport activity of ABCB1(a major transmembrane efflux pump belonging to the ABC transporter superfamily), it also exhibits growth inhibitory activity against larvae of Drosophila melanogaster. |
| CFN90945 | Cheilanthifoline Cheilanthifoline has anti-osteoclastogenic property, it gives significant inhibitions on receptor activator of nuclear factor-κB ligand-induced differentiation of mouse bone marrow-derived macrophages into multinucleated osteoclasts. Cheilanthifoline also shows promising in vitro antiplasmodial activities against Plasmodium falciparum. |
| CFN90943 | Isovitexin 2''-O-arabinoside Isovitexin 2''-O-arabinoside is a natural product from Secale cereale. |
| CFN90942 | Kaempferol 3-sophoroside-7-glucoside Kaempferol 3-sophoroside-7-glucoside is a natural product from Equisetum hyemale L. |
| CFN89524 | 2-Hydroxy-4-methoxybenzaldehyde 2-Hydroxy-4-methoxybenzaldehyde is an excellent antimicrobial agent with additional antiaflatoxigenic potency. 2-Hydroxy-4-methoxybenzaldehyde has antioxidant and high antimycotic potency, it possesses chemosensitizing capability to magnify the efficacy of monoterpenoid phenols, which improves target-based (viz., cell wall disruption) antifungal intervention. |
| CFN89520 | Retusin Retusin behaves as pre- and postemergent herbicides. Retusin is a weak inhibitor of ATP synthesis; it exhibits potent free-radical-scavenging capacities as well as efficient inhibition of cellular melanogenesis. |
| CFN89471 | Ambocin Ambocin is a natural product from Pueraria mirifica. |
| CFN89459 | Geissoschizine methyl ether Geissoschizine methyl ether is a potent serotonin ₁A receptor agonist and candidate for amelioration of aggressiveness and sociality by yokukansan, it has third-generation antipsychotic-like actions at the dopamine and serotonin receptors. Geissoschizine methyl ether is a strong acetylcholinesterase (AChE) inhibitor, it inhibited 50% of AChE activity at concentrations of 3.7 ± 0.3 ug/mL. Geissoschizine methyl ether protects neurons from oxidative toxicity by shifting energy metabolism from mitochondrial respiration to glycolysis. Geissoschizine methyl ether has vasorelaxant effect, which is composed of two different mechanisms: endothelial dependency with nitric oxide and endothelial independency with voltage-dependent Ca(2+)-channel blocking. |
| CFN89443 | 3'-Methoxydaidzin 3'-Methoxydaidzin has antioxidation activity, it may be a potential neuroprotective substance in Gegen Qinlian decoction. |
| CFN89438 | 1-O-Acetylbritannilactone 1-O-Acetylbritannilactone has anticancer activity, it suppresses angiogenesis and lung cancer cell growth possibly via regulating the VEGFR-Src-FAK signaling, it also can combine with gemcitabine elicits a potent apoptosis of lung cancer cell. 1-O-Acetylbritannilactone may serve as a novel therapeutic intervention for various cardiovascular diseases, including chronic ischemia, by regulating VEGF signaling and modulating angiogenesis; it is a potent inhibitor of LPS-stimulated VSMC inflammatory responses through blockade of NF-kappaB activity and inhibition of inflammatory gene COX-2 expression. 1-O-Acetylbritannilactone may act as potent natural skin-lightening agents, it exhibits anti-melanogenic activity by suppression of tyrosinase expression via ERK and Akt signaling. |
| CFN89436 | Axinysone B Axinysone B is a natiral product from the metabolites of the mushroom Anthracophyllum sp. BCC18695. |
| CFN89431 | (-)-Isolariciresinol 9'-O-glucoside Reference standards. |
| CFN89430 | Dehydrodiconiferyl alcohol 4-O-beta-D-glucopyranoside Dehydrodiconiferyl alcohol 4-O-beta-D-glucopyranoside is a natural product from Ligusticopsis wallichiana (DC) Pimenov & Kljuykov. |
| CFN89426 | 11-Anhydro-16-oxoalisol A Reference standards. |
| CFN89421 | Viscumneoside III Viscumneoside III demonstrates high tyrosinase inhibition, it can be utilized in skin whitening cosmetics. |
| CFN89420 | Tupichinol A Tupichinol A is a natural product from Tupistra chinensis. |
| CFN89419 | Debilon Debilon shows cytotoxic activity against P-388 cells. |
| CFN89408 | Glycycoumarin Glycycoumarin is an estrogen agonist, it shows moderate inhibitory effects against CYP1A2 and CYP2B6. Glycycoumarin has anti-liver cancer, neuroprotective, antioxidant and anti-inflammatory activities. Glycycoumarin has anti-hepatitis C virus (HCV) activity, with the IC(50) value of 8.8, ug/mL. Glycycoumarin has an inhibitory effect on smooth muscle contraction induced by various types of stimulants through the inhibition of PDEs, especially isozyme 3, followed by the accumulation of intracellular cAMP; it also can inhibit hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress/GSK-3-mediated mitochondrial pathway. |
| CFN89404 | Glycyrin Glycyrin, one of the main PPAR-gamma ligands of licorice, can significantly decrease the blood glucose levels of genetically diabetic KK-A(y) mice. Glycyrin exhibits anti-BsFtsZ GTPase activities, at levels comparable to that of the synthetic FtsZ inhibitor, Zantrin Z3. Glycyrin has anti-hepatitis C virus (HCV) activity with the IC(50) value of 7.2 ug/mL; it shows antibacterial activity against upper airway respiratory tract bacteria such as Streptococcus pyogenes, Haemophilus influenzae and Moraxella catarrhalis; it also possesses weaker anti-Helicobacter pylori activity, it may be a useful chemopreventive agent for peptic ulcer or gastric cancer in H. pylori-infected individuals. |
| CFN89389 | 7-Xylosyl-10-deacetyltaxol B |
| CFN89385 | 7-Xylosyl-10-deacetyltaxol C 7-Xylosyl-10-deacetyltaxol C is a natural product from Taxus wallichiana Zucc. |
| CFN89340 | Bruceine E Bruceine E exhibits significant blood glucose concentration reduction activity, it might act as an insulin secretagogue. |
| CFN89332 | Isohomoarbutin Isohomoarbutin is a natural product from Pyrola rotundifolia. |
| CFN89328 | Aristola-1(10),8-dien-2-one Reference standards. |
| CFN89313 | Adoxosidic acid Adoxosidic acid is a natural product from Cistanche tubulosa (Schenk) R. Wight. |
| CFN89307 | 2,6,4'-Trihydroxy-4-methoxybenzophenone 2,6,4'-Trihydroxy-4-methoxybenzophenone shows weak inhibitory activity of testosterone 5alpha-reductase, it also shows significant inhibition of pancreatic lipase activity. 2,6,4'-Trihydroxy-4-methoxybenzophenone has neurotrophic activity, it induced neurite outgrowth in PC-12 cells at concentration of 50 microg/ml. 2,6,4′-Trihydroxy-4-methoxybenzophenone exhibits low cytotoxic effect against HeLa and 3T3 cell lines with IC50 values of 132 ug/ml and 158 ug/ml, repectively. It also shows antioxidant activity on DPPH with IC50 of 10.57 ug/mL. |
| CFN89301 | Matairesinoside Matairesinoside is a natural product from Styrax japonica. |
| CFN89297 | Nyasol Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory properties by inhibiting iNOS expression; it also has antifungal activity, it is significantly effective in suppressing the Phytophthora blight on pepper plants. (-)-Nyasol exhibits the half maximal inhibitory concentration (IC50) value of 17.6 uM against D-glycero-α-D-manno-heptose-1-phosphate guanylyltransferase (HddC). (+)-Nyasol has antiprotozoal activity, it potently inhibits the growth of Leishmania major promastigotes, the IC50 being 12 microM, and moderately inhibits Plasmodium falciparum schizonts with the IC50 49 microM. |
