Natural Products
| Catalog No. | Information |
| CFN90943 | Isovitexin 2''-O-arabinoside Isovitexin 2''-O-arabinoside is a natural product from Secale cereale. |
| CFN90942 | Kaempferol 3-sophoroside-7-glucoside Kaempferol 3-sophoroside-7-glucoside is a natural product from Equisetum hyemale L. |
| CFN89524 | 2-Hydroxy-4-methoxybenzaldehyde 2-Hydroxy-4-methoxybenzaldehyde is an excellent antimicrobial agent with additional antiaflatoxigenic potency. 2-Hydroxy-4-methoxybenzaldehyde has antioxidant and high antimycotic potency, it possesses chemosensitizing capability to magnify the efficacy of monoterpenoid phenols, which improves target-based (viz., cell wall disruption) antifungal intervention. |
| CFN89520 | Retusin Retusin behaves as pre- and postemergent herbicides. Retusin is a weak inhibitor of ATP synthesis; it exhibits potent free-radical-scavenging capacities as well as efficient inhibition of cellular melanogenesis. |
| CFN89471 | Ambocin Ambocin is a natural product from Pueraria mirifica. |
| CFN89459 | Geissoschizine methyl ether Geissoschizine methyl ether is a potent serotonin ₁A receptor agonist and candidate for amelioration of aggressiveness and sociality by yokukansan, it has third-generation antipsychotic-like actions at the dopamine and serotonin receptors. Geissoschizine methyl ether is a strong acetylcholinesterase (AChE) inhibitor, it inhibited 50% of AChE activity at concentrations of 3.7 ± 0.3 ug/mL. Geissoschizine methyl ether protects neurons from oxidative toxicity by shifting energy metabolism from mitochondrial respiration to glycolysis. Geissoschizine methyl ether has vasorelaxant effect, which is composed of two different mechanisms: endothelial dependency with nitric oxide and endothelial independency with voltage-dependent Ca(2+)-channel blocking. |
| CFN89443 | 3'-Methoxydaidzin 3'-Methoxydaidzin has antioxidation activity, it may be a potential neuroprotective substance in Gegen Qinlian decoction. |
| CFN89438 | 1-O-Acetylbritannilactone 1-O-Acetylbritannilactone has anticancer activity, it suppresses angiogenesis and lung cancer cell growth possibly via regulating the VEGFR-Src-FAK signaling, it also can combine with gemcitabine elicits a potent apoptosis of lung cancer cell. 1-O-Acetylbritannilactone may serve as a novel therapeutic intervention for various cardiovascular diseases, including chronic ischemia, by regulating VEGF signaling and modulating angiogenesis; it is a potent inhibitor of LPS-stimulated VSMC inflammatory responses through blockade of NF-kappaB activity and inhibition of inflammatory gene COX-2 expression. 1-O-Acetylbritannilactone may act as potent natural skin-lightening agents, it exhibits anti-melanogenic activity by suppression of tyrosinase expression via ERK and Akt signaling. |
| CFN89436 | Axinysone B Axinysone B is a natiral product from the metabolites of the mushroom Anthracophyllum sp. BCC18695. |
| CFN89431 | (-)-Isolariciresinol 9'-O-glucoside Reference standards. |
| CFN89430 | Dehydrodiconiferyl alcohol 4-O-beta-D-glucopyranoside Dehydrodiconiferyl alcohol 4-O-beta-D-glucopyranoside is a natural product from Ligusticopsis wallichiana (DC) Pimenov & Kljuykov. |
| CFN89426 | 11-Anhydro-16-oxoalisol A Reference standards. |
| CFN89421 | Viscumneoside III Viscumneoside III demonstrates high tyrosinase inhibition, it can be utilized in skin whitening cosmetics. |
| CFN89419 | Debilon Debilon shows cytotoxic activity against P-388 cells. |
| CFN89408 | Glycycoumarin Glycycoumarin is an estrogen agonist, it shows moderate inhibitory effects against CYP1A2 and CYP2B6. Glycycoumarin has anti-liver cancer, neuroprotective, antioxidant and anti-inflammatory activities. Glycycoumarin has anti-hepatitis C virus (HCV) activity, with the IC(50) value of 8.8, ug/mL. Glycycoumarin has an inhibitory effect on smooth muscle contraction induced by various types of stimulants through the inhibition of PDEs, especially isozyme 3, followed by the accumulation of intracellular cAMP; it also can inhibit hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress/GSK-3-mediated mitochondrial pathway. |
| CFN89404 | Glycyrin Glycyrin, one of the main PPAR-gamma ligands of licorice, can significantly decrease the blood glucose levels of genetically diabetic KK-A(y) mice. Glycyrin exhibits anti-BsFtsZ GTPase activities, at levels comparable to that of the synthetic FtsZ inhibitor, Zantrin Z3. Glycyrin has anti-hepatitis C virus (HCV) activity with the IC(50) value of 7.2 ug/mL; it shows antibacterial activity against upper airway respiratory tract bacteria such as Streptococcus pyogenes, Haemophilus influenzae and Moraxella catarrhalis; it also possesses weaker anti-Helicobacter pylori activity, it may be a useful chemopreventive agent for peptic ulcer or gastric cancer in H. pylori-infected individuals. |
| CFN89389 | 7-Xylosyl-10-deacetyltaxol B |
| CFN89385 | 7-Xylosyl-10-deacetyltaxol C 7-Xylosyl-10-deacetyltaxol C is a natural product from Taxus wallichiana Zucc. |
| CFN89340 | Bruceine E Bruceine E exhibits significant blood glucose concentration reduction activity, it might act as an insulin secretagogue. |
| CFN89332 | Isohomoarbutin Isohomoarbutin is a natural product from Pyrola rotundifolia. |
| CFN89328 | Aristola-1(10),8-dien-2-one Reference standards. |
| CFN89307 | 2,6,4'-Trihydroxy-4-methoxybenzophenone 2,6,4'-Trihydroxy-4-methoxybenzophenone shows weak inhibitory activity of testosterone 5alpha-reductase, it also shows significant inhibition of pancreatic lipase activity. 2,6,4'-Trihydroxy-4-methoxybenzophenone has neurotrophic activity, it induced neurite outgrowth in PC-12 cells at concentration of 50 microg/ml. 2,6,4′-Trihydroxy-4-methoxybenzophenone exhibits low cytotoxic effect against HeLa and 3T3 cell lines with IC50 values of 132 ug/ml and 158 ug/ml, repectively. It also shows antioxidant activity on DPPH with IC50 of 10.57 ug/mL. |
| CFN89301 | Matairesinoside Matairesinoside is a natural product from Styrax japonica. |
| CFN89297 | Nyasol Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory properties by inhibiting iNOS expression; it also has antifungal activity, it is significantly effective in suppressing the Phytophthora blight on pepper plants. (-)-Nyasol exhibits the half maximal inhibitory concentration (IC50) value of 17.6 uM against D-glycero-α-D-manno-heptose-1-phosphate guanylyltransferase (HddC). (+)-Nyasol has antiprotozoal activity, it potently inhibits the growth of Leishmania major promastigotes, the IC50 being 12 microM, and moderately inhibits Plasmodium falciparum schizonts with the IC50 49 microM. |
| CFN89281 | 4'-O-Methylnyasol 4'-O-Methylnyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. |
| CFN89280 | Kobusin Kobusin, a Calmodulin inhibitor, shows mild antiplasmodial,anti-inflammatory, and cytotoxic activities; it may be beneficial for the treatment of neuro-inflammatory diseases through the inhibition of iNOS expression and peroxynitrite scavenging potential. Kobusin can mildly reduce gastrointestinal motility in mice, it activates CFTR and CaCCgie chloride channel activities in mouse colonic epithelia and shows inhibitory effects toward ANO1/CaCC-mediated short-circuit currents in ANO1/CaCC-expressing FRT cells. |
| CFN89274 | Olivil 4'-O-glucoside Olivil 4'-O-glucoside is a natural product from Gentianella acuta. |
| CFN89254 | Diversoside Diversoside is a natural product from Aster subspicatus. |
| CFN89231 | ar-Turmerone ar-Turmerone could be used as a low cost botanical insecticide for integrated management of cabbage looper in vegetable production. ar-Turmerone also shows larvicidal and biting deterrent activity against Aedes aegypti and Anopheles quadrimaculatus (Culicidae: Diptera). ar-Turmerone may have notable antibacterial activity to Bacillus cereus and Staphylococcus aureus, antifungal activity to Aspergillus niger, and cytotoxic activity to Hs 578T (breast tumor) and PC-3 (prostate tumor) cells. ar-Turmerone displays neuroprotective, and anticonvulsant properties, it exerts potent anti-inflammatory effects via suppression of the inflammatory cytokines IFN-γ and IL-2. |
| CFN89228 | 6-(4-Hydroxy-3-methylphenyl)-2-methylhept-2-en-4-one Reference standards. |
| CFN89177 | Chloranthalactone E Chloranthalactone E is a natural product from Chloranthus serratus. |
| CFN89146 | Nudiposide Nudiposide has significant neuroprotective activities against glutamate-injured neurotoxicity in HT22 cells. It also exhibits protective effect against sepsis in a mouse model and can decrease the plasma levels of TNF-α, IL-10 and ALT activity. |
| CFN89144 | Arjunglucoside II Arjunglucoside II exhibits a moderate free radical scavenging activity. |
| CFN89113 | 2-Hydroxy-3-methoxybenzoic acid glucose ester 2-Hydroxy-3-methoxybenzoic acid glucose ester shows a potent antagonistic activity against platelet activating factor (PAF), it can prevent the mice from the PAF-induced death at a dose of 300 micrograms/mouse. |
| CFN89067 | Angeloylgomisin O Angeloylgomisin O is a nartural product from Schisandra chinensis. |
| CFN89019 | Gelidoside Gelidoside is a natural product from Gentiana siphonantha. |
| CFN89016 | Intermedin B Intermedin B is a natural product from Alpinia intermedia. |
| CFN96989 | 2-Deacetoxytaxinine J 2-Deacetoxytaxinine J shows significant in vitro activity against breast cancer cell line at a concentration of 20 microM and 10 microM in MCF-7 and MDA-MB-231 respectively. |
| CFN96977 | Kanshone A Kanshone A shows cytotoxic activity against P-388 cells. |
| CFN96956 | Protosappanin A Protosappanin A has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB inflammation signal pathway; it exerts anti-neuroinflammatory effect by inhibiting JAK2-STAT3 pathway in lipopolysaccharide-induced BV2 microglia. Protosappanin A induces immunosuppression of rats heart transplantation targeting T cells in grafts via NF-kappaB pathway. Protosappanin A and protosappanin B have antimicrobial activity, they show both alone activities and resistance reversal effects of amikacin and gentamicin against MRSA. Protosappanin A shows strong effect against HIV-1 IN with an IC50 value of 12.6 uM. |
| CFN96939 | Benzoylgomisin H Benzoylgomisin H is a natural product from Schizandra chinensis. |
| CFN96901 | Epiaschantin (+)-Epiaschantin shows marginal cancer cell line inhibitory activities. It also has anti-platelet aggregation activity. |
| CFN96878 | 1-Methoxyphaseollidin 1-Methoxyphaseollidin exhibits anti-Helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains. 1-Methoxyphaseollidin may show moderate cytotoxic activity against KB and L1210 cells. 1-Methoxyphaseollidin also shows inhibition of lysoPAF acetyltransferase activity. |
| CFN96858 | 3,5-Dihydroxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)heptane (3R,5R)-3,5-dihydroxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)-heptane may have anti-adipogenic activity. |
| CFN96857 | 3-Methoxymollugin 3-Methoxymollugin is a cytotoxic compound. |
| CFN96842 | Gancaonin I Gancaonin I exhibits anti-BsFtsZ GTPase activities; it also shows significant inhibitory activity against B. subtilis, with a MIC value of 5 uM. |
| CFN96790 | 1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one (4Z,6E)-5-hydroxy-1,7-bis(4-hydroxyphenyl)hepta-4,6-dien-3-one shows growth inhibitory activity in vitro versus bloodstream forms of African trypanosomes, with the IC(50) value in the range of 1-3 microg/mL. |
| CFN96770 | O-Nornuciferine O-Nornuciferine reveals distinct in vitro human ether-à-go-go related gene (hERG) blockages measured in HEK293 cells with the IC50 value of 2.89 uM. |
| CFN96764 | 3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid 2-O-beta-d-Glucosyloxy-4-methoxybenzenepropanoic acid[3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid] exhibits glutathione S-transferase (GST) inhibitory and antifungal activities. |
| CFN96754 | 6'-O-Cinnamoyl-8-epikingisidic acid 6'-O-Cinnamoyl-8-epikingisidic acid is a natural product from Ligustrum lucidum. |
