Natural Products
| Catalog No. | Information |
| CFN89019 | Gelidoside Gelidoside is a natural product from Gentiana siphonantha. |
| CFN89016 | Intermedin B Intermedin B is a natural product from Alpinia intermedia. |
| CFN96989 | 2-Deacetoxytaxinine J 2-Deacetoxytaxinine J shows significant in vitro activity against breast cancer cell line at a concentration of 20 microM and 10 microM in MCF-7 and MDA-MB-231 respectively. |
| CFN96977 | Kanshone A Kanshone A shows cytotoxic activity against P-388 cells. |
| CFN96956 | Protosappanin A Protosappanin A has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB inflammation signal pathway; it exerts anti-neuroinflammatory effect by inhibiting JAK2-STAT3 pathway in lipopolysaccharide-induced BV2 microglia. Protosappanin A induces immunosuppression of rats heart transplantation targeting T cells in grafts via NF-kappaB pathway. Protosappanin A and protosappanin B have antimicrobial activity, they show both alone activities and resistance reversal effects of amikacin and gentamicin against MRSA. Protosappanin A shows strong effect against HIV-1 IN with an IC50 value of 12.6 uM. |
| CFN96939 | Benzoylgomisin H Benzoylgomisin H is a natural product from Schizandra chinensis. |
| CFN96901 | Epiaschantin (+)-Epiaschantin shows marginal cancer cell line inhibitory activities. It also has anti-platelet aggregation activity. |
| CFN96878 | 1-Methoxyphaseollidin 1-Methoxyphaseollidin exhibits anti-Helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains. 1-Methoxyphaseollidin may show moderate cytotoxic activity against KB and L1210 cells. 1-Methoxyphaseollidin also shows inhibition of lysoPAF acetyltransferase activity. |
| CFN96858 | 3,5-Dihydroxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)heptane (3R,5R)-3,5-dihydroxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)-heptane may have anti-adipogenic activity. |
| CFN96857 | 3-Methoxymollugin 3-Methoxymollugin is a cytotoxic compound. |
| CFN96842 | Gancaonin I Gancaonin I exhibits anti-BsFtsZ GTPase activities; it also shows significant inhibitory activity against B. subtilis, with a MIC value of 5 uM. |
| CFN96790 | 1,7-Bis(4-hydroxyphenyl)hepta-4,6-dien-3-one (4Z,6E)-5-hydroxy-1,7-bis(4-hydroxyphenyl)hepta-4,6-dien-3-one shows growth inhibitory activity in vitro versus bloodstream forms of African trypanosomes, with the IC(50) value in the range of 1-3 microg/mL. |
| CFN96770 | O-Nornuciferine O-Nornuciferine reveals distinct in vitro human ether-à-go-go related gene (hERG) blockages measured in HEK293 cells with the IC50 value of 2.89 uM. |
| CFN96764 | 3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid 2-O-beta-d-Glucosyloxy-4-methoxybenzenepropanoic acid[3-(2-Glucosyloxy-4-methoxyphenyl)propanoic acid] exhibits glutathione S-transferase (GST) inhibitory and antifungal activities. |
| CFN96754 | 6'-O-Cinnamoyl-8-epikingisidic acid 6'-O-Cinnamoyl-8-epikingisidic acid is a natural product from Ligustrum lucidum. |
| CFN96732 | (-)-Lyoniresinol 9'-O-glucoside (-)-Lyoniresinol 9'-O-glucoside is a natural product from Phyllostachys heterocycla MITF. |
| CFN96694 | Pregomisin Pregomisin shows platelet-activating factor (PAF) antagonistic activity and the IC 50 value is 4.8x10(-5) M. |
| CFN96685 | Rutaevin Rutaevin shows the inhibitory activity on nitric oxide (NO) production in lipopolysaccharide-activated RAW264.7 macrophages, it may be as a valuable anti-inflammatory agent. |
| CFN96617 | Tigloylgomisin P Tigloylgomisin P shows moderate to marginal cytotoxicity against A549, PC-3, KB and KBvin human cancer cell lines. |
| CFN96606 | Trifloroside Trifloroside is a bitter iridoid glycoside. |
| CFN96588 | Hastatoside Hastatoside and verbenalin are major sleep-promoting components of V. officinalis. Hastatoside has anti-inflammatory activity. |
| CFN96586 | p-Hydroxyphenethyl anisate p-Hydroxyphenethyl anisate is a natural product from Notopterygium incisum. |
| CFN96567 | Dehydrodiconiferyl alcohol Dehydrodiconiferyl alcohol shows anti-adipogenic and anti-lipogenic effects in 3T3-L1 cells and primary mouse embryonic fibroblasts. Dehydrodiconiferyl alcohol can modulate the differentiation of Th17 and Th1 cells and suppress experimental autoimmune encephalomyelitis, it may be a potential candidate as an agent for the control of Th17 and Th1-mediated inflammatory diseases. (+)-(2S,3R)-Dehydrodiconiferyl alcohol is an antioxidant, it has an inhibitory effect on VCAM-1 expression via JNK pathway in endothelial cells and therefore may serve as a novel pharmacological agent to improve endothelial dysfunction. |
| CFN96557 | Iridin |
| CFN96544 | Licoisoflavanone Licoisoflavanone is a natural product from Licorice. |
| CFN96539 | Taxifolin 7-O-rhamnoside Taxifolin 7-O-rhamnoside is a natural product from Hypericum japonicum. |
| CFN96523 | Glyasperin D Glyasperin D possesses weak anti-Helicobacter pylori activity. |
| CFN96515 | Licoflavonol Licoflavonol is a novel natural inhibitor of Salmonella T3SS, could be a promising candidate for novel type of anti-virulence drugs, it exhibits a strong inhibitory effect on the secretion of the SPI-1 effector proteins via regulating the transcription of the SicA/InvF genes, and the transportation of the effector protein SipC. |
| CFN96513 | Sophoraisoflavone A Sophoraisoflavone A is a potential MRP inhibitor; it is also an inhibitor of germ tube growth in the AM fungus Gigaspora margarita, it strongly inhibited germ tube growth at 1.25 ug/disc. Sophoraisoflavone A shows inhibitory effects on copper-induced protein oxidative modification of mice brain homogenate in vitro. |
| CFN96508 | Cirsiliol Cirsiliol shows antioxidant, and anti-obesity effects, it can inhibit TG accumulation in 3T3-L1 preadipocytes. Cirsiliol and rhamnetin can act as promising radiosensitizers that enhance the radiotherapeutic efficacy by inhibiting radiation-induced Notch-1 signaling associated with radioresistance possibly via miR-34a-mediated pathways. |
| CFN96505 | Isoangustone A Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation by targeting PI3K, MKK4, and MKK7 in human melanoma. Isoangustone A dampens mesangial sclerosis associated with inflammation in response to high glucose through hindering TGF-β and NF-κB signaling. Isoangustone A also shows strong ferric reducing activities and effectively scavenged DPPH, ABTS(+), and singlet oxygen radicals. |
| CFN96504 | Licoricone Licoricone exhibits anti-helicobacter pylori activity against the CLAR and AMOX-resistant strain as well as four CLAR (AMOX)-sensitive strains. |
| CFN96484 | Corynoxidine Corynoxidine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains. It inhibits acetylcholinesterase activity in a dose-dependent manner, and the IC50 value of 89.0 microM. |
| CFN95013 | (R)-Reticuline (R)-Reticuline is the biosynthetic precursor of the morphinan alkaloids. |
| CFN95012 | Alloisoimperatorin Alloisoimperatorin is a candidate of AChE inhibitors, it displays potent antioxidant effects against the DPPH radical and against renal epithelial cell injury by using AAPH to generate peroxyl radicals in vitro. Alloisoimperatorin has estrogenic activity on the Ishikawa cell line, it shows strong ability to induce alkaline phosphatase (AP) with the EC50 values of 0.8 microg/mL. |
| CFN90881 | Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose can moderately inhibit α-amylase activity, with the IC50 value of 0.03 umol/ml. |
| CFN90879 | Pinoresinol dimethyl ether Pinoresinol dimethyl ether, which could be isolated from the wood of the basal tree Humbertieae, show a variety of activities as the inhibitor of cyclic AMP phosphodiesterase. |
| CFN95011 | Glucoliquiritin Reference standards. |
| CFN96465 | Urolignoside Urolignoside shows antioxidant and radical scavenging activity. |
| CFN95010 | Suchilactone Suchilactone may have the potential to be developed as a treatment of Alzheimer's Disease. |
| CFN96440 | Cauloside A Cauloside A exhibits concentration- and time-dependent mitochondriotoxic activities. |
| CFN96432 | Bisacurone Bisacurone has anti-oxidant, anti-inflammatory, and anti-metastatic activities, it may have a protective effect against ethanol-induced liver injury by suppressing hepatic oxidation and inflammation. |
| CFN96422 | Yadanzioside G Yadanzioside G has antileukemic activity. |
| CFN96416 | Yangambin Yangambin is a selective antagonist of the cardiovascular effects of platelet activating factor (PAF); it has hypotensive effect, which is probably due to a peripheral vasodilatation that involves, at least, the inhibition the Ca2+ influx through voltage-gated Ca2+ channels. Yangambin has central nervous system activity, it presents a depressant activity in the open field, forced swimming and pentobarbital sleeping time tests. |
| CFN96405 | Licoisoflavone B Licoisoflavone B is an inhibitor of germ tube growth in the arbuscular mycorrhizal (AM) fungus Gigaspora margarita, it can strongly inhibit germ tube growth at 0.63 ug/disc, and it can completely inhibit hyphal branching induced by a lupin strigolactone, orobanchyl acetate, in G. margarita at 0.16 ug/disc. Licoisoflavone B exhibits inhibitory activity against the growth of Helicobacter pylori in vitro, it also shows anti-H. pylori activity against a clarithromycin (CLAR) and amoxicillin (AMOX)-resistant strain.Licoisoflavone B exhibits antimutagenic activity against carcinogenic N-methyl-N-nitrosourea (MNU), it is important to prevent DNA damage by N-nitrosamines for cancer chemoprevention. |
| CFN96399 | Sideritoflavone Sideritoflavone has anti-inflammatory effect, it is a selective inhibitor of lipoxygenase activity in vitro. |
| CFN96395 | Zanthobungeanine Zanthobungeanine has anti-inflammatory activity, it shows moderate NO production inhibitory activity with an IC50 value of 37.26 mg /L.It shows obviously inhibitoryactivity to platelet aggregation caused by platelet-activating factor (PAF). Zanthobungeanine shows the inhibitory action on the development of A549 cell only in high concentration and has no antipersonnel effect on A549 cell. |
| CFN96389 | Licoricidin Licoricidin, is a potent anti-metastatic agent, which can markedly inhibit the metastatic and invasive capacity of malignant prostate cancer cells. Licoricidin and licorisoflavan A are effective in inhibiting the growth of all three bacterial species(Porphyromonas gingivalis, Prevotella intermedia and Solobacterium moorei), with minimal inhibitory concentrations in the range of 2-80 ug /ml, they have a potential for reducing bacterial volatile sulfur compounds (VSCs) production and therefore for controlling halitosis; they also have potential for the development of novel host-modulating strategies for the treatment of cytokine and/or MMP-mediated disorders such as periodontitis. Licoricidin may be considered as an active ingredient in new topically applied anti-ageing formulations, it blocks UVA-induced photoaging via ROS scavenging,this activity converges to limit the activity of MMP-1. |
| CFN96362 | Robustine Robustine may have anti-inflammatory activity, it exhibits inhibition (IC 50 < or = 18.19 microM) of superoxide anion generation by human neutrophils in response to formyl- l-methionyl- l-leucyl- l-phenylalanine/cytochalasin B (FMLP/CB). |
| CFN96355 | Splendoside Standard reference |
