Natural Products
| Catalog No. | Information |
| CFN90861 | Continentalic acid Continentalic acid and kaurenoic acid are quality control markers in Aralia continentalis. Continentalic acid has anti-inflammatory, anti-cancer, and anti-bacterial activities, it shows moderate cytotoxicity against A-549 (lung), THP-1 (leukemia) and MCF-7 (breast) cell lines; it has minimum inhibitory concentrations (MICs) of approximately 8-16 microg/mL against S. aureus, including the MSSA and MRSA standard strains. |
| CFN90859 | Notoginsenoside Ft1 Notoginsenoside Ft1 is a novel stimulator of angiogenesis, it stimulates angiogenesis via HIF-1α-mediated VEGF expression, with PI3K/AKT and Raf/MEK/ERK signaling cascades concurrently participating in the process; it has the potential therapeutic effect on human neuroblastoma, it can arrest the proliferation and elicited the apoptosis of SH-SY5Y cells possibly via p38 MAPK and ERK1/2 pathways.Notoginsenoside Ft1 activates both glucocorticoid and estrogen receptors to induce endothelium-dependent, nitric oxide-mediated relaxations in rat mesenteric arteries. Notoginsenoside Ft1 also provides a great potential application of it in clinics for patients with diabetic foot ulcers, it may accelerate diabetic wound healing by orchestrating multiple processes, including promoting fibroblast proliferation, enhancing angiogenesis, and attenuating inflammatory response. |
| CFN96255 | Lupeolic acid Lupeolic acid has anti-inflammatory activity. |
| CFN96248 | Hannokinol (+)-Hannokinol and MESO-hannokinol can significantly inhibit lipopolysaccharide-induced nitric oxide production in BV2 microglial cells at concentrations ranging from 1 microM to 100 microM. |
| CFN96238 | Juglanin Juglanin has anti-tumor, antioxidant,and hepatoprotective activities. Juglanin shows protective effects on fructose-induced hepatitis by inhibiting inflammation and apoptosis through TLR4 and JAK2/STAT3 signaling pathways in fructose-fed rats. Juglanin can lead to G2/M phase arrest, induce apoptosis as well as autophagy through the ROS/JNK signaling pathway in human breast cancer cells |
| CFN90858 | 4,5-Di-O-caffeoylquinic acid methyl ester 4,5-Di-O-caffeoylquinic acid methyl ester shows high efficiency and low toxicity with antivirus activity against RSV. |
| CFN90857 | 3,5-Di-O-caffeoylquinic acid methyl ester 3,5-Di-O-caffeoylquinic acid methyl ester exhibits potent inhibitory activities against the formation of advanced glycation end products (AGEs); it exhibits cytotoxicity actions against human cervix carcinoma HeLa cells. 3,5-Di-O-caffeoylquinic acid methyl ester shows high efficiency and low toxicity with antivirus activity against RSV. |
| CFN90856 | 3,4-Di-O-caffeoylquinic acid methyl ester 3,4-Di-O-caffeoylquinic acid methyl ester shows high efficiency and low toxicity with antivirus activity against RSV; it exhibits cytotoxicity actions against human cervix carcinoma HeLa cells. |
| CFN96224 | Kaempferol 7-O-rhamnoside Kaempferol 7-O-rhamnoside is a natural product from Maytenus hookeri. |
| CFN96221 | 3,7-Di-O-methylquercetin 3,7-Di-O-methylquercetin shows α-glucosidase inhibition. |
| CFN90855 | Quercetagetin-7-O-glucoside Quercetagetin-7-O-glucoside, a potent inhibitor of beta-glucuronidase and lysozyme release, shows anti-inflammatory activity, can significantly inhibit arachidonic acid release from membranes. |
| CFN90839 | Isomucronulatol Isoliquiritigenin and liquiritigenin exhibit significant inhibitory effects on LPS-induced IL-6 and IL-12 p40 production, with IC 50 values ranging from 2.7 to 6.102uM, isoliquiritigenin also shows a moderate inhibitory effect on LPS-stimulated production of TNF-α with an IC 50 value of 20.102 uM, they have potential anti-inflammatory effects. Isomucronulatol exhibits noticeable ABTS+ scavenging activity, it exhibits moderate inhibition against butyrylcholinesterase. |
| CFN90838 | Methylnissolin Methylnissolin is a natural product from A. membranaceus. |
| CFN92889 | 5-O-Feruloylquinic acid 5-O-feruloylquinic acid is a potent Sirt1 agonist, it is a potential lead compound that can be further tested in drug development process for diseases associated with aging. |
| CFN95006 | cis-Mulberroside A cis-Mulberroside A shows high analgesic and anti-inflammatory activities, it can protect mice against ethanol-induced hepatic damage. |
| CFN90831 | Galloylpaeoniflorin Galloylpaeoniflorin exhibits anticomplement effects, it reveals a more pronounced radical scavenging effect than a-tocopherol. Galloylpaeoniflorin can take part in improving blood circulation by inhibiting ether platelet aggregation and/or blood coagulation. Galloylpaeoniflorin exhibits good activity on acute lung injury. |
| CFN90830 | 3,3'-Di-O-methylellagic acid 4'-glucoside Reference standards. |
| CFN90829 | 20(21)-Dehydrolucidenic acid A 20(21)-dehydrolucidenic acid A is a natural product from Ganoderma lucidum. |
| CFN90827 | Rubrofusarin-6-O-beta-D-gentiobioside Rubrofusarin-6-O-beta-D-gentiobioside can significantly decrease the expression of TGF-beta1 and fibronectin and NF-kappaB DNA binding activity, suggests that it has potential as a preventive agent for advanced glycation end products-related diabetic complications. |
| CFN90826 | Cassiaside Cassiaside has significant hepato-protective effects against galactosamine damage, which is higher than that of silybin from Silybum marianum. Cassiaside demonstrates significant antimutagenic, and 1,1-diphenyl-2-picrylhydrazyl(DPPH) radical scavenging effects. Cassiaside and emodi show mixed-type inhibition against β-site amyloid precursor protein (APP) cleaving enzyme 1 (BACE1). |
| CFN95005 | Apterin Apterin has anti-inflammatory activity in vitro, it shows significantly inhibitory activity on nitric oxide production in RAW264.7 cells. |
| CFN95004 | Decuroside I Decuroside I shows weak inhibiting activity against the primary and secondary wave aggregation of human platelet. |
| CFN95003 | Pd-C-II Pd-C-II has anti-inflammation activity, it can inhibit TNF-α production and iNOS protein expression and inhibit COX-2 protein expression in LPS-stimulated RAW 264.7 cells. Pd-C-II inhibits anaphylactic mediator release from purified mast cells induced by concanavalin A with phosphatidylserine, the IC50 value of 79 microM. |
| CFN95002 | Decursitin D Decursitin D is a natural product from the roots of Peucedanum decursivum. |
| CFN95001 | Oroselol Oroselol, jatamansinol, nardostachysin, jatamansinone and nardosinone are Nardostachys jatamansi rhizome extract marker compounds. |
| CFN90819 | Mauritianin Mauritianin and (+)-syringaresinol as new topoisomerase I inhibitors. Mauritianin has statistically significant cytoprotective activity similar to that of silymarin, tested at 60 ug/mL. |
| CFN90818 | Semilicoisoflavone B Semilicoisoflavone B can inhibit sorbitol formation of rat lens incubated with a high concentration of glucose, indicates that it may be effective for preventing osmotic stress in hyperglycemia. |
| CFN90817 | Glycyrrhisoflavone Glycyrrhisoflavone is a tyrosinase inhibitor, it also shows inhibitory effects on monoamine oxidase. Glycybenzofuran shows significant protein tyrosine phosphatase-1B (PTP1B) inhibitory activity in vitro with the IC50 value of 25.5 microM. Glycyrrhisoflavone has anti-inflammatory effects, it has significant inhibitory effects against NO production on LPS-induced RAW 264.7 cell model. |
| CFN90816 | Licoisoflavone A Licoisoflavone A is a potential MRP inhibitor, it shows inhibitory effects on copper-induced protein oxidative modification of mice brain homogenate in vitro. |
| CFN90815 | Effusol Effusol can induce caspase-3-mediated cytotoxicity in HT22 cells. |
| CFN90814 | Dehydroeffusol Dehydroeffusol possesses anti-cancer, anxiolytic and sedative properties, it may antagonize the spasmogenic activity of various agents, and therefore, could be a promising agent in the treatment of spasms. Dehydroeffusol displays enhanced antimicrobial activities in light, its antimicrobial activities (minimum inhibitory concentrations) against methicillin-resistant and -sensitive Staphylococcus aureus and Candida albicans are increased 16 fold by irradiation with ultraviolet A (UVA). |
| CFN90813 | Juncusol Juncusol shows anxiolytic and sedative activities, it shows anxiolytic activity at dosages of 10 mg/kg; it can induce caspase-3-mediated cytotoxicity in HT22 cells. Juncusol has anti-microbial activity, it shows significant activity against MRSA strains. |
| CFN90810 | 9'''-Methyl salvianolate B Reference standards. |
| CFN90804 | 3-O-Acetyl-16 alpha-hydroxytrametenolic acid 3-O-Acetyl-16 alpha -hydroxytrametenolic acid has inhibitory activities against AAPH-induced hemolysis of red blood cells, it shows a strong inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate-induced inflammation in mice. 3-O-Acetyl-16 alpha-hydroxytrametenolic acid markedly inhibited the promoting effect of 12-O-tetradecanoylphorbol-13-acetate (1 microgram/mouse) on skin tumor formation following initiation with 7,12-dimethylbenz[a]anthracene (50 micrograms/mouse). |
| CFN93114 | Parishin C Parishin C has antipsychotic effects, requires activation of 5-HT(1A) receptors, it can prevent vascular dementia. |
| CFN93113 | Parishin B Parishin B has good neuroprotective effects against brain disorders, it can prevent vascular dementia. |
| CFN93112 | Parishin A Parishin A has good neuroprotective effects against brain disorders. |
| CFN90915 | Tubeimoside II Tubeimoside I, tubeimoside II, and tubeimoside III show anti-inflammatory, antitumor, and antitumor-promo ting effects. |
| CFN90916 | Tubeimoside III Tubeimoside III has anti-inflammatory, anti-tumor, and anti-tumorigenic activities, stronger than those of tubeimoside II. It has acute toxicity, stronger than that of tubeimoside II. |
| CFN93284 | Notoginsenoside Fa Notoginsenosides Fa and R4 show significant neurite outgrowth enhancing activities in human neuroblastoma SK-N-SH cells. |
| CFN90911 | Desoxyrhaponticin Desoxyrhaponticin is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes. Desoxyrhaponticin could be considered as a promising fatty acid synthase(FAS) inhibitor, it could inhibit intracellular FAS activity and downregulate FAS expression in human breast cancer MCF-7 cells. |
| CFN90921 | 5-O-Demethylnobiletin 5-O-Demethylnobiletin has anti-inflammatory activity, it may act through a direct inhibition of 5-LOX, without affecting the expression of COX-2. |
| CFN93368 | Escin IA Escin IA is a prodrug and its structure can be converted to desacylescin I by human intestinal bacteria and Lactobacillus brevis., desacylescin I as a biotransformation product shows potentially inhibitory effects on mouse tumor, and a potential candidate for anti tumor agents. Escin IA has anti-TNBC metastasis activity, and its action mechanisms involved inhibition of EMT process by down-regulating LOXL2 expression. |
| CFN93115 | Parishin E Parishin E is a natural product from Gastrodia elata. |
| CFN93187 | Luteolin-3-O-beta-D-glucuronide Luteolin 3'-O-beta-D-glucuronide is active in the inhibition of nitrite production in macrophages. |
| CFN93199 | Methylnissolin-3-O-glucoside (6aR,11aR)-9,10-Dimethoxypterocarpan 3-O-β-D-glucoside(Methylnissolin-3-O- glucoside) has antioxidant activity. |
| CFN93260 | Platycodin D2 Platycodin D2 , a less hemolytic saponin, can improve specific cellular and humoral responses to hepatitis B surface antigen in mice, it could be safely used as adjuvant eliciting Th1 and Th2 immune responses. Polygalacin D2 has anti-cancer activity, it exhibits significant inhibition on the proliferation of five kinds of cultured human tumor cell lines. |
| CFN93577 | Cratoxylone 1. Cratoxylone exhibits potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with the IC₅₀ value belows 3 uM. |
| CFN93585 | Quercetin-3-gentiobioside Quercetin-3-gentiobioside may show significant inhibitor on AR and AGEs formation activities. |
| CFN93096 | 2''-O-Beta-L-Galorientin Reference standards. |
