Natural Products
| Catalog No. | Information |
| CFN92296 | Chebulinic acid Chebulinic acid is a potent natural inhibitor of M. tuberculosis DNA gyrase, also can inhibit SMAD-3 phosphorylation, inhibit H+ K+-ATPase activity; it also is a natural inhibitor of vascular endothelial growth factor-A mediated angiogenesis. Chebulinic acid has hypotensive, antioxidant, anti-HIV, and anti-ulcer activities. Chebulinic acid has inhibitory effect on erythroid differentiation likely through changing transcriptional activation of differentiation relative genes, it or other tannins might influence the efficiency of some anti-tumor drugs-induced differentiation or the hematopoiesis processes. |
| CFN92295 | Chebulagic acid Chebulagic acid is a potent DNA topoisomerase inhibitor, and is also COX-2 and 5-LOX dual inhibitor. Chebulagic acid may be of value as broad-spectrum antivirals for limiting emerging/ recurring viruses known to engage host cell glycosaminoglycans for entry. Chebulagic acid can be used to control blood glucose and manage type 2 diabetes, although clinical trials are needed. |
| CFN92290 | Ganoderic acid C6 Ganoderic acid C6 has antinociceptive activity. |
| CFN92288 | (+)-Epipinoresinol Reference standards. |
| CFN92285 | Chrysin 6-C-glucoside 8-C-arabinoside Chrysin-6-C-arabinosyl-8-C-glucoside and chrysin-6-C-glucosyl-8-C-arabinoside are α-glucosidase inhibitors, α-glucosidase inhibitors are widely used in the treatment of type 2 diabetes. |
| CFN92284 | Chrysin 6-C-arabinoside 8-C-glucoside Chrysin-6-C-arabinosyl-8-C-glucoside and chrysin-6-C-glucosyl-8-C-arabinoside are α-glucosidase inhibitors, α-glucosidase inhibitors are widely used in the treatment of type 2 diabetes. |
| CFN92280 | Glychionide A Reference standards. |
| CFN92279 | Chrysin 7-O-beta-D-glucopyranuronoside Reference standards. |
| CFN92269 | Deapi-platycodin D3 Deapi-platycodin and platycodinD, aqueous extract of the root of Platycodon grandiflorum A. de Candolle (APG), can regulate the production and secretion of airway mucin and, at least in part, explains the traditional use of aqueous extract of APG as expectorants in diverse inflammatory pulmonary diseases. |
| CFN92268 | Platyconic acid A Platyconic acid A suppresses the development of respiratory inflammation, hyperresponsiveness, and remodeling by reducing allergic responses, and it may be a potential herbal drug for allergen-induced respiratory disease prevention. Platyconic acid A suppresses PMA-induced MUC5AC mRNA expression by inhibiting NF-κB activation via Akt in A549 cells. |
| CFN92265 | cis-Tiliroside Kaempferol-3-O-β-D-(6''-O-coumaryl) glycoside has antioxidant activity and α-glucosidase inhibitory effects, it could potentially be used for food additives and the development of useful natural compounds. |
| CFN92238 | Ganoderenic acid C Reference standards. |
| CFN92237 | Ganoderic acid T-Q Ganoderic acid T-Q and TR are two inhibitors of H5N1 and H1N1 NAs. |
| CFN92235 | Ganoderic acid TR Ganoderic acid TR, a new lanostanoid with 5α-reductase inhibitory activity from the fruiting body of Ganoderma lucidum. |
| CFN92226 | Corylifol A Corylifol A is a naturally occurring potent inhibitor of hCE2 and UDP-glucuronosyltransferase 1A1 (UGT1A1); it could be the potential uncouplers of neuronal nitric oxide synthase-postsynaptic density protein-95. Corylifol A displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. Corylifol A has antiinflammatory activity, it shows an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells with IC50 values of 0.81 ± 0.15 uΜ, it also inhibits STAT3 phosphorylation induced by IL-6 in Hep3B cells. |
| CFN92225 | Isopsoralenoside Isopsoralenoside shows estrogen-like, osteoblastic proliferation accelerating, antitumor, and antibacterial effects. |
| CFN92224 | Psoralenoside Psoralenoside is a narture product from Psoralea corylifolia. |
| CFN92222 | Neobavaisoflavone Neobavaisoflavone, exhibits inhibitory activity against DNA polymerase and platelet aggregation, it also has striking anti-inflammatory and anti-cancer effects, Neobavaisoflavone can significantly inhibit the production of reactive oxygen species (ROS), reactive nitrogen species (RNS) and cytokines: IL-1β, IL-6, IL-12p40, IL-12p70, TNF-α in LPS+IFN-γ- or PMA- stimulated RAW264.7 macrophages. |
| CFN92218 | Norwogonin Norwogonin(IC 50 = 1.1 microM) shows potent inhibitory activity toward VHR. |
| CFN92216 | Skullcapflavone II Skullcapflavone II is a flavonoid derived from Scutellaria baicalensis, a widely used herbal medicine in anti-inflammatory and anticancer therapy in Korea. Skullcapflavone II may have therapeutic potential for the treatment of allergic asthma. |
| CFN92205 | Picrasidine Q Picrasidine Q has the capacity of anti-cell transformation and anti-cancer, it might be a chemopreventive and chemotherapeutic agent by direct targeting FGFR2 and inhibiting cell proliferation of ESCC cells. |
| CFN92203 | Mogroside II-A2 Mogroside II-A2 is a natural product from Siraitia grosvenorii Swingle. |
| CFN92202 | Chiirirhamnin Chiirirhamnin is a natural product from Aconitum chiisanense. |
| CFN92193 | Mogroside III-A1 Mogroside III-A1 is a natural product from Siraitia grosvenorii Swingle. |
| CFN92192 | 11-Oxomogroside III 11-Oxomogroside III is a natural product from Siraitia grosvenorii Swingle. |
| CFN92191 | Mogroside IIe Mogroside IIe is a bitter triterpenoid saponin which is the main component of unripe Luo Han Guo fruit and a precursor of the commercially available sweetener mogroside V. |
| CFN92190 | Mogroside III The human intestinal bacteria shows potent ability to transform Mogroside III to release secondary glycoside mogroside II(A1) and aglycone mogrol. |
| CFN92188 | Mogroside IVa Mogroside IVa is a natural product from Siraitia grosvenorii Swingle. |
| CFN92179 | Methylenetanshinquinone Methylenetanshinquinone shows antiplasmodial and antitrypanosomal activity, it is active against both Trypanosoma brucei rhodesiense and Plasmodium falciparum. |
| CFN92172 | Quercetin-3-O-glucuronide Quercetin-3-O-glucuronide is a potent stilbene oxidase inhibitor, it has antioxidant, anti-atherogenic, and anti-inflammatory activities. Quercetin-3-O-glucuronide significantly improves Alzheimer's disease (AD)-type deficits in hippocampal formation basal synaptic transmission and long-term potentiation, possibly through mechanisms involving the activation of the c-Jun N-terminal kinases and the mitogen-activated protein kinase signaling pathways. Quercetin-3-O-glucuronide is equally effective in inhibiting ROS-associated inflammation and ameliorating insulin resistant endothelial dysfunction by beneficial regulation of IRS-1 function. |
| CFN92171 | Delphinidin-3-sambubioside chloride Delphinidin-3-sambubioside chloride has antioxidant activity. Delphinidin-3-sambubioside might induce apoptosis in HL-60 cells through a ROS-mediated mitochondrial dysfunction pathway. |
| CFN92137 | Delphinidin-3,5-O-diglucoside chloride Delphinidin-3,5-O-diglucoside chloride has antioxidant activity. |
| CFN92129 | Eurycomalactone Eurycomalactone as a potent NF-κB inhibitor with the IC50 value of less than 1 uM. It shows antiplasmodial activity against Gombak A isolate. Eurycomalactone displays potent activity against all the tested cell lines [colon 26-L5 carcinoma (IC50 = 0.70 microM), B16-BL6 melanoma (IC50 = 0.59 microM), Lewis lung carcinoma (IC50 = 0.78 microM), and a human lung A549 adenocarcinoma (IC50 = 0.73 microM)]. |
| CFN92127 | 9,10-Dimethoxycanthin-6-one 9,10-Dimethoxycanthin-6-one shows cytotoxic activity against a HT-1080 human fibrosarcoma cell line( IC50 = 5.0 microM). |
| CFN92125 | 11-Hydroxycanthin-6-one 11-Hydroxy-canthin-6-one has antineoplastic activity. |
| CFN92113 | 6-O-benzoylgomisin O 6-O-benzoylgomisin O is a natural product from Schisandra sphenanthera. |
| CFN92111 | 2-Hydroxy-1-methoxyanthraquinone 2-Hydroxy-1-methoxy- anthraquinone has antiosteoporotic activity, it can promote osteoblast proliferation, and can inhibit osteoclast TRAP activity and bone resorption. |
| CFN92110 | 2-(Hydroxymethyl)anthraquinone 2-(Hydroxymethyl)anthraquinone exhibits strong activity against Helicobacter pylori ATCC 43504 at 0.01 mg/disc. |
| CFN92109 | Digitolutein Digitolutein has inhibition on the growth of Plasmodium falciparum in vitro. |
| CFN92108 | Asperulosidic acid Asperulosidic acid has been recently used in chinese medicine as a useful drug against some tumors. It has anticlastogenic activity, since the anticlastogenic irridoids have an alpha-unsaturated carbonyl group, this structure is considered to play an important role in the anticlastogenicity. Asperulosidic acid can inhibit the seed germination and growth of seedlings of large crabgrass. Asperulosidic acid, and 6-O-(beta-D-glucopyranosyl)-1-O-octanoyl-beta-D-glucopyranose are effective in suppressing 12-O-tedtradecanoylphorbol-13-acetate (TPA)- or epidermal growth factor (EGF)-induced cell transformation and associated AP-1 activity. |
| CFN92101 | 30-Hydroxygambogic acid 30-Hydroxygambogic acid exhibits significant cytotoxicities against the human leukemia K562/S and the corresponding doxorubicin-resistant K562/R cell lines. |
| CFN92100 | 10alpha-Hydroxyepigambogic acid Reference standards. |
| CFN92098 | Epigambogic acid Isogambogic acid shows cytotoxic activiity against KB and drug-resistant KB-V1 cell lines. |
| CFN92097 | Gambogenic acid Gambogenic acid is an inhibitor of the FGFR signaling pathway in erlotinib-resistant non-small-cell lung cancer (NSCLC) and exhibits anti-tumor effects, it can cause aberrant autophagy to induce cell death and may suggest the potential application of Gambogenic acid as a tool or viable drug in anticancer therapies.Gambogenic acid could inhibit the proliferation of melanoma B16 cells and induce their apoptosis within certain time and concentration ranges. Its mechanism in inducing the cell apoptosis may be related to PI3K/Akt/mTOR signaling pathways. |
| CFN92096 | Isogambogenic acid Isogambogenic acid inhibits angiogenesis and may be a viable drug candidate in anti-angiogenesis therapy. Isogambogenic acid exhibits an anticancer effect by inducing autophagy-dependent cell death in NSCLC cells, which may be an effective chemotherapeutic agent that can be used against NSCLC in a clinical setting. |
| CFN92094 | Isomorellic acid Isomorellic acid is a cytotoxic caged xanthone. |
| CFN92093 | Morellic acid Morellic acid has anti-cancer activity, it strongly inhibited the migration of HUVEC at a low concentration of 0.5 μM in HUVEC cell migration assay in vitro. Morellic acid also has antiangiogenic activity. |
| CFN92092 | 2alpha-hydroxy-3beta-acetyloxy-betulic acid Reference standards. |
| CFN92088 | Desoxygambogenin Desoxygambogenin is a cytotoxic xanthone, it has anti-HIV-1 activity. |
| CFN90495 | Phellopterin Phellopterin is a partial agonist of the central benzodiazepine receptors in vitro; it shows cytotoxic effect on RAW264.7 cell at the concentration from 40 to 400 μM. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium. |
