Natural Products
| Catalog No. | Information |
| CFN96157 | Ayanin Ayanin has vasorelaxant activity, it also may have the potential for use in treating allergic asthma.The IC(50) value of Ayanin (quercetin-3,7,4'-O-trimethylether) is 2.2microM for inhibiting interleukin (IL)-4 production from purified basophils. |
| CFN96158 | Hydrocinnamic acid Hydrocinnamic acid inhibits the currents of WT and SQT3 syndrome-related mutants of Kir2.1 channel. |
| CFN96159 | 16-O-Acetylpolyporenic acid C Standard reference |
| CFN96160 | Cyclo(Gly-L-Pro) Cyclo(Gly-(L)-Pro) shows immunostimulatory properties. Cyclo(Gly-l-Pro) exhibits potent inhibition of TNF-α release with the IC50 values of 4.5 ug/mL, respectively, it also exhibits significant diminution of IL-1β and IL-6 mRNA-expression levels and NO production. |
| CFN96161 | Eudesm-4(15)-ene-3alpha,11-diol Reference standards. |
| CFN90757 | Ginsenoside F4 Ginsenoside F4 has inhibitory effect on human lymphocytoma JK cell by inducing its apoptosis, the mechanism is related to the mitochondrial dysfunction and the increase of Bax expression and decrease of Bcl-2 expression. Ginsenoside F4 also has strongly inhibit activation of p38 mitogen-activated protein kinase in signal transduction pathways. |
| CFN93152 | L-Phenylalanine L-Phenylalanine has antibacterial activity. |
| CFN90758 | Oxyepiberberine Reference standards. |
| CFN90759 | Ajugol Ajugol shows some trypanocidal potential against Trypanosoma brucei rhodesiense (IC50 values 29.3–73.0 ug/ml). |
| CFN90760 | Rehmapicroside Reference standards. |
| CFN90761 | Rehmannioside A Rehmannioside A is an iridoid glucoside. |
| CFN93818 | Campestanol Campestanol, which shares the same basic structure and intestinal absorption pathway with cholesterol, does not accumulate when fed, and may be incorporated into the diet to block cholesterol absorption. |
| CFN93091 | L-carnosine L-carnosine is an antioxidant naturally found in skeletal muscle, brain tissue, and the heart that protects cells against oxidative stress.L-carnosine plays an important role in inhibiting neuronal cell apoptosis through STAT3 signaling pathway after acute cerebral ischemia. L-carnosine may accelerate pressure ulcer healing during 4 weeks. |
| CFN96162 | Barbinervic acid Barbinervic acid shows anti-bacteria activity (IC50 = 0.098 g x LU(-1), IC50 = 0.27 g x L(-1)) against SA and ESBLs-SA respectively. |
| CFN96163 | 2,3-Dihydroamentoflavone 7,4'-dimethyl ether 2,3-Dihydroamentoflavone 7,4'-dimethyl ether exhibits cytotoxicities (ED50 values < 4 microg/mL) against P-388 and/or HT-29 cell lines in vitro. |
| CFN96164 | 3'-Methyl-4-O-methylhelichrysetin Reference standards. |
| CFN96165 | 9-O-Methyl-4-hydroxyboeravinone B 9-O-Methyl-4-hydroxyboeravinone B is a promising candidate for cancer therapy. |
| CFN96166 | Orientanol A Orientanol A is a natural product from Erythrina arborescens. |
| CFN96167 | 4beta-Carboxy-19-nortotarol 4 beta-Carboxy-19-nortotarol can inhibit microsomal lipid peroxidation induced by Fe(III)-ADP/NADPH and mitochondrial lipid peroxidation induced by Fe(III)-ADP/ NADH, it inhibits linoleic acid autoxidation but not generation of superoxide anion. |
| CFN96168 | 1''-Hydroxyerythrinin C Reference standards. |
| CFN96169 | Pyrocurzerenone |
| CFN96170 | Spegatrine Spegatrine is a natural product from Rauvolfia verticillata. |
| CFN96171 | 3-Hydroxy-3-acetonyloxindole Standard reference |
| CFN96172 | Magnaldehyde D Magnaldehyde D is a natural product from Magnolia officinalis. |
| CFN96173 | Mirabijalone D Mirabijalone D is a non-competitive inhibitor based on the Dixon plot.It inhibits Aβ1–42 production by 43.7% in APPSW-N2a cells. |
| CFN96174 | Dehydrochromolaenin Reference standards. |
| CFN90762 | Epimedoside A Epimedoside A has significant antioxidant activity in vitro. |
| CFN90763 | Baohuoside V Reference standards. |
| CFN90764 | Baohuoside II Baohuoside aglycone possesses cardioprotective effect in prevention of ischemia/ reperfusion injury and reduce the myocardial infraction, the mechnism is due to the reduction of the injury of free radicals. |
| CFN90765 | Baohuoside VII Baohuoside aglycone possesses cardioprotective effect in prevention of ischemia/ reperfusion injury and reduce the myocardial infraction, the mechnism is due to the reduction of the injury of free radicals. Baohuoside VII in vivo exhibits significant anti-osteoporosis activity. |
| CFN90766 | Isokurarinone Isokurarinone is a natural product from Sophora flavescens Ait. |
| CFN90767 | Sophoflavescenol Sophoflavescenol is a mixed inhibitor of PDE5 with a K(i) value of 0.005 microM. Sophoflavescenol has antioxidant, anti-inflammatory, and apoptotic effects , these effects might contribute to the antitumor activity without severe side effects. Sophoflavescenol exerts notable anti-inflammatory activity by inhibiting nitric oxide generation and tert-butylhydroperoxide-induced ROS generation rather than inhibiting nuclear factor kappa B activation in RAW 264.7 cells. |
| CFN90768 | Isoxanthohumol Isoxanthohumol is a polyphenol with antioxidant, anti-inflammatory, and antiangiogenic properties, seems to regulate in vivo vascular proliferation and stabilization and the EC-VSMC-inflammatory crosstalk. Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV). |
| CFN90769 | Cochinchinenin A The combination of Cochinchinenin A, cochinchinenin B, and loureirin B is the material basis for the analgesic effect of Dragon’s Blood. |
| CFN96175 | 6'-O-Galloyl paeoniflorin 6'-O-Galloylpaeoniflorin (GPF) may be developed as a cytoprotector against ROS-mediated oxidative stress, GPF demonstrates a significant scavenging capacity against the 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical, H2O2-generated intracellular reactive oxygen species (ROS), the superoxide anion radical (O2 -), and the hydroxyl radical (•OH); GPF also can safeguarde HaCaT keratinocytes against H2O2-provoked apoptotic cell death and attenuated oxidative macromolecular damage to DNA, lipids, and proteins; GPF exerts its cytoprotective actions in keratinocytes at least in part by decreasing the number of DNA strand breaks, the levels of 8-isoprostane (a stable end-product of lipid peroxidation), and the formation of carbonylated protein species. GPF shows strong androgen receptor (AR) binding activity. |
| CFN93213 | Streptozotocin Streptozotocin, which produces diabetes mellitus in experimental animals, has been reported to reduce the level of NAD in pancreatic isletsand to inhibit islet synthesis of proinsulin.Streptozotocin can induce pancreatic insulitis, which is a new model of diabetes mellitus. |
| CFN90770 | Tenuifoliside A Tenuifoliside A has anti-apoptotic,neuroprotective,and anti-inflammatory effects, it inhibits the NF-κB and MAPK pathways. |
| CFN93211 | Vanillyl alcohol Vanillyl alcohol possesses anti-angiogenic, anticonvulsive, anti-inflammatory, anti-oxidant, neuroprotective, and anti-nociceptive activities. Vanillyl alcohol can effectively inhibit the cytotoxicity and improved cell viability in 1-methyl-4-phenylpyridinium (MPP+)-induced MN9D dopaminergic cells, it also can attenuate the elevation of reactive oxygen species (ROS) levels, decrease in the Bax/Bcl-2 ratio and poly (ADP-ribose) polymerase proteolysis. |
| CFN90771 | Bruceine D Bruceine D has anti-cancer activity, it inhibits the growth of three pancreatic cancer cell lines, i.e., PANC-1, SW1990 and CAPAN-1; induces cytotoxicity in Capan-2 cells via the induction of cellular apoptosis involving the mitochondrial pathway.Bruceine D may have the potential to be used as a natural viricide, or a lead compound for new viricides. |
| CFN90772 | Cussosaponin C Reference standards. |
| CFN90773 | Soyasaponin Ab Soyasaponin Ab may represent a viable candidate for effective vaccine adjuvant, TLR4 receptor dependent pathway may be involved in immune stimulatory effects of soyasaponin Ab. Soyasaponin Ab has anti-inflammatory effects, it can inhibit colon shortening, myeloperoxidase activity, the expression of cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS), and activation of the transcription factor nuclear factor-κB (NF-κB); soyasaponin Ab (1, 2, 5, and 10 μM) can inhibit the production of NO (IC50 = 1.6 ± 0.1 uM) and prosta. Soyasaponin Aa and Ab can markedly inhibit adipocyte differentiation and expression of various adipogenic marker genes through the downregulation of the adipogenesis-related transcription factors PPARγ and C/EBPα in 3T3-L1 adipocytes. They also can prevent scopolamine-induced memory impairment in mice without the inhibition of acetylcholinesterase, exhibit memory-enhancing effects. |
| CFN90774 | Soyasaponin Ac Soyasaponin Ac can decrease the drug resistance via EMT pathway and weaken the migration ability of ovarian cancer cells. |
| CFN93221 | 4-Methoxybenzoic acid 4-Methoxybenzoic acid could be used as raw material in cosmetic and dermatologic products and/or aroma components in foodstuffs, it has antioxidant,antiinflammatory and antimicrobial activities. |
| CFN90781 | Saponin V Saponin V exhibits significant antitussive, expectorant and antispasmodic effects, it (300,150,75 mg·kg-1) can significantly decrease the times of cough, saponin V 300 mg/kg can remarkably increase cough latent period, saponin V 5 g/L remarkably antagonized contraction of isolated ileum, saponin V 2.5 and 1.25 g/L antagonized trachea spasm in guinea pig induced by histamine.Chikusetsu saponin V exhibits neuroprotective effects, it can attenuate H2O2-induced oxidative stress in human neuroblastoma SH-SY5Y cells through Sirt1/PGC-1α/Mn-SOD signaling pathways. |
| CFN90775 | Soyasaponin Bd 1. Soyasaponins has chemoprevention activities, it prevent H₂O₂-induced inhibition of gap junctional intercellular communication by scavenging reactive oxygen species in rat liver cells. 2. Soyasaponins can significantly decrease blood glucose, improve atherosclerotic index, and inhibit lipid peroxidation and platelet aggregation in diabetic rats, which may be useful in prevention and control of diabetes mellitus and diabetes-associated atherosclerosis. 3. Soyasaponins abundant in soybean have anti-inflammatory activities, low-dose SSs alleviated contact hypersensitivity (CHS) symptoms by attenuating inflammation and improving the intestinal microbiota composition, suggesting that dietary SSs may have beneficial effects on allergic contact dermatitis (ACD). 4. Dietary soyasaponin has inhibitory effects on 2,4-dinitrofluorobenzene-induced contact hypersensitivity in mice. |
| CFN90776 | Soyasaponin Be 1. Soyasaponins has chemoprevention activities, it prevent H₂O₂-induced inhibition of gap junctional intercellular communication by scavenging reactive oxygen species in rat liver cells. 2. Soyasaponins can significantly decrease blood glucose, improve atherosclerotic index, and inhibit lipid peroxidation and platelet aggregation in diabetic rats, which may be useful in prevention and control of diabetes mellitus and diabetes-associated atherosclerosis. 3. Soyasaponins abundant in soybean have anti-inflammatory activities, low-dose SSs alleviated contact hypersensitivity (CHS) symptoms by attenuating inflammation and improving the intestinal microbiota composition, suggesting that dietary SSs may have beneficial effects on allergic contact dermatitis (ACD). 4. Dietary soyasaponin has inhibitory effects on 2,4-dinitrofluorobenzene-induced contact hypersensitivity in mice. |
| CFN90777 | Soyasaponin Be methyl Ester 1. Soyasaponins has chemoprevention activities, it prevent H₂O₂-induced inhibition of gap junctional intercellular communication by scavenging reactive oxygen species in rat liver cells. 2. Soyasaponins can significantly decrease blood glucose, improve atherosclerotic index, and inhibit lipid peroxidation and platelet aggregation in diabetic rats, which may be useful in prevention and control of diabetes mellitus and diabetes-associated atherosclerosis. 3. Soyasaponins abundant in soybean have anti-inflammatory activities, low-dose SSs alleviated contact hypersensitivity (CHS) symptoms by attenuating inflammation and improving the intestinal microbiota composition, suggesting that dietary SSs may have beneficial effects on allergic contact dermatitis (ACD). 4. Dietary soyasaponin has inhibitory effects on 2,4-dinitrofluorobenzene-induced contact hypersensitivity in mice. |
| CFN90778 | Anemarsaponin BIII Reference standards. |
| CFN90779 | Timorsaponin C Reference standards. |
| CFN90780 | 3'-Methoxypuerarin 3'-Methoxypuerarin shows neuron protection activity, it can protect hippocampal neurons against ischemia/reperfusion injury by inhibiting apoptosis. 3'-Methoxypuerarin has antioxidant activities, it shows ONOO(-) scavenging activity and weak NO· and O(2)(-) scavenging activities. |
