Natural Products
| Catalog No. | Information |
| CFN93088 | Nerylacetate Nerylacetate and 1,5-dienes geranyl acetate are catalyzed to the cis-2,5-bis(hydroxymethyl)tetrahydrofurans 3 and 4 by OsO4. |
| CFN93287 | Beta-pinene Beta-pinene shows anti- bacteria activity, it also exhibits antiherpetic activity in the early phase of viral multiplication and might be used as potential antiviral agents. Beta-pinene exerts supraspinal antinociceptive actions in rats only and it reversed the antinociceptive effect of morphine in a degree equivalent to naloxone, probably acting as a partial agonist through the mu opioid receptors. |
| CFN93285 | Alpha-pinene Alpha-pinene inhibits the nuclear translocation of NF-kappa B induced by LPS in THP-1 cells, and this effect is partly due to the upregulation of I kappa B alpha expression. Alpha-pinene inhibits early root growth and causes oxidative damage in root tissue through enhanced generation of ROS, as indicated by increased lipid peroxidation, disruption of membrane integrity and elevated antioxidant enzyme levels. |
| CFN93004 | Ethyl 4-hydroxyphenylacetate Ethyl 4-hydroxyphenylacetate is a selective inhibitor of monoamine oxidase A. |
| CFN90823 | Neoisoliquiritin Neoisoliquiritin is a natural product from Glycyrrhiza uralensis. |
| CFN93169 | Cyclopentadecanone Used in perfumery (musk odour). |
| CFN95001 | Oroselol Oroselol, jatamansinol, nardostachysin, jatamansinone and nardosinone are Nardostachys jatamansi rhizome extract marker compounds. |
| CFN95002 | Decursitin D Decursitin D is a natural product from the roots of Peucedanum decursivum. |
| CFN95003 | Pd-C-II Pd-C-II has anti-inflammation activity, it can inhibit TNF-α production and iNOS protein expression and inhibit COX-2 protein expression in LPS-stimulated RAW 264.7 cells. Pd-C-II inhibits anaphylactic mediator release from purified mast cells induced by concanavalin A with phosphatidylserine, the IC50 value of 79 microM. |
| CFN95004 | Decuroside I Decuroside I shows weak inhibiting activity against the primary and secondary wave aggregation of human platelet. |
| CFN95005 | Apterin Apterin has anti-inflammatory activity in vitro, it shows significantly inhibitory activity on nitric oxide production in RAW264.7 cells. |
| CFN96194 | Vitexdoin A Vitexdoin A is a natural product from Vitex negundo. |
| CFN90824 | 4'-Prenyloxyresveratrol 4'-Prenyloxyresveratrol is a natural product from Morus wittiorum. |
| CFN90825 | 7-Prenylumbelliferone 7-Prenylumbelliferone is a natural product from Heracleum dissectum. |
| CFN90826 | Cassiaside Cassiaside has significant hepato-protective effects against galactosamine damage, which is higher than that of silybin from Silybum marianum. Cassiaside demonstrates significant antimutagenic, and 1,1-diphenyl-2-picrylhydrazyl(DPPH) radical scavenging effects. Cassiaside and emodi show mixed-type inhibition against β-site amyloid precursor protein (APP) cleaving enzyme 1 (BACE1). |
| CFN90827 | Rubrofusarin-6-O-beta-D-gentiobioside Rubrofusarin-6-O-beta-D-gentiobioside can significantly decrease the expression of TGF-beta1 and fibronectin and NF-kappaB DNA binding activity, suggests that it has potential as a preventive agent for advanced glycation end products-related diabetic complications. |
| CFN90828 | 3,7,4'-Trihydroxy-5-methoxy-8-prenylflavanone Reference standards. |
| CFN90829 | 20(21)-Dehydrolucidenic acid A 20(21)-dehydrolucidenic acid A is a natural product from Ganoderma lucidum. |
| CFN90830 | 3,3'-Di-O-methylellagic acid 4'-glucoside Reference standards. |
| CFN90831 | Galloylpaeoniflorin Galloylpaeoniflorin exhibits anticomplement effects, it reveals a more pronounced radical scavenging effect than a-tocopherol. Galloylpaeoniflorin can take part in improving blood circulation by inhibiting ether platelet aggregation and/or blood coagulation. Galloylpaeoniflorin exhibits good activity on acute lung injury. |
| CFN90832 | Zingiberen newsaponin Zingiberensis newsaponin I exhibits induction effect on platelet aggregation. Zingiberensis saponin can inhibit the proliferation of a panel of established human and murine cancer cell lines in vitro, its proliferation inhibitory effect is associated with its apoptosis-inducing effect by activation of caspase-3 and caspase-9 and specific proteolytic cleavage of poly (ADP-ribose) polymerase, thus, zingiberensis saponin is an effective natural agent for cancer therapy. |
| CFN90833 | Chrysin 7-O-beta-gentiobioside Chrysin 7-O-beta-gentiobioside is a natural product from Spartium junceum. |
| CFN90834 | Kuwanon A |
| CFN90835 | Kuwanon H Kuwanon H, and possibly kuwanon G also, are specific antagonists for the gastrin-releasing peptide (GRP) -preferring receptor and can be useful for studying the physiological and pathological role of GRP. |
| CFN90836 | Sanggenone H Sanggenone H may have antiphlogistic activity, it attenuated the secretion of TNF-α and IL-1β and inhibited the NF-κB nuclear translocation in LPS-stimulated macrophages. |
| CFN95006 | cis-Mulberroside A cis-Mulberroside A shows high analgesic and anti-inflammatory activities, it can protect mice against ethanol-induced hepatic damage. |
| CFN90837 | 10-Deacetyl-7-xylosyl paclitaxel 10-Deacetyl-7-xylosyl paclitaxel has long been used in Chinese clinics to treat cancer, it may target mitochondrial permeability transition pore (mPTP). |
| CFN92889 | 5-O-Feruloylquinic acid 5-O-feruloylquinic acid is a potent Sirt1 agonist, it is a potential lead compound that can be further tested in drug development process for diseases associated with aging. |
| CFN93150 | Soyasapogenol A Soyasapogenol A shows estrogenic and hepatoprotective activities, it directly prevents apoptosis of hepatocytes, and secondly, inhibits the elevation of plasma TNF-α, which consequently resulted in the prevention of liver damage in the concanavalin A-induced hepatitis model. |
| CFN93159 | Soyasaponin II Soyasaponin II has antiviral effects, it can inhibit the replication of human cytomegalovirus, influenza virus, and human immunodeficiency virus type 1. Soyasaponin II has hepatoprotective actions towards immunologically induced liver injury on primary cultured rat hepatocytes. It can inhibit the conversion of fibrinogen to fibrin, it also can promote activation of the fibrinolytic system in a plasminogen-containing fibrin plate. Soyasaponins are a potential antitumor compound and the apoptosis induced by soyasaponins is a key antitumor mechanism. |
| CFN93251 | Soyasaponin IV Soyasaponin IV has hepatoprotective activity.It also has antimutagenic activity in mammalian cells. |
| CFN90838 | Methylnissolin Methylnissolin is a natural product from A. membranaceus. |
| CFN90839 | Isomucronulatol Isoliquiritigenin and liquiritigenin exhibit significant inhibitory effects on LPS-induced IL-6 and IL-12 p40 production, with IC 50 values ranging from 2.7 to 6.102uM, isoliquiritigenin also shows a moderate inhibitory effect on LPS-stimulated production of TNF-α with an IC 50 value of 20.102 uM, they have potential anti-inflammatory effects. Isomucronulatol exhibits noticeable ABTS+ scavenging activity, it exhibits moderate inhibition against butyrylcholinesterase. |
| CFN90840 | Rubrosterone Rubrosterone is an insect-molting C19-steroid. |
| CFN90841 | Leptomerine Leptomerine (IC₅₀ = 2.5 mM) shows potent anticholinesterasic activity. |
| CFN90842 | (9Z,12Z)-N-Benzyloctadeca-9,12-dienamide Reference standards. |
| CFN90843 | Macamide B Reference standards. |
| CFN90844 | N-Benzyloleamide N-benzyloleamide has pharmaceutical property against exercise-induced fatigue, and this effect can be explained by the modulated energy metabolism and improved antioxidant status. |
| CFN90845 | (9Z,12Z)-N-(3-Methoxybenzyl)octadeca-9,12-dienamide |
| CFN90846 | N-(3-Methoxybenzyl)palmitamide N-(3-methoxybenzyl)palmitamide is a promising inhibitor of fatty acid amide hydrolase (FAAH) and could potentially offer a good alternative for the treatment of pain, inflammation and CNS degenerative disorders. N-(3-Methoxybenzyl)palmitamide can counteract the toxicity produced by Aβ (25-35). |
| CFN90847 | N-(3-Methoxybenzyl)oleamide Macamides (N-(3-methoxybenzyl)oleamide (MAC 18:1), N-(3-methoxybenzyl)linoleamide (MAC 18:2) and N-(3-methoxybenzyl)linolenamide (MAC 18:3) )achieve their neuroprotective effects by binding to CB1 receptors to protect against Mn-induced toxicity in U-87 MG glioblastoma cells. Additionally these macamides, in a manner similar to the analogous endocannabinoid AEA, interact with other targets such as PPARγ to regulate metabolism and energy homeostasis, cell differentiation and inflammation. |
| CFN90848 | Osthol hydrate Reference standards. |
| CFN93321 | Tamoxifen Tamoxifen is currently the first-line therapy for treatment of hormone-dependent breast cancer, it acts as an estrogen agonist by preventing the skeletal alterations that result from ovarian hormone deficiency. |
| CFN93261 | Cisplatin Cisplatin is a antineoplastic chemotherapy drug which works by cross-linking with DNA and causing DNA damage in cancer cells, it can enhance the cell-killing effect of radiation, an effect whose intensity varies with the schedule of administration. |
| CFN93222 | Kakuol Kakuol has antifungal activity, it can completely inhibit the mycelial growth of Botrytis cinerea Pers ex Fr and Cladosporium cucumerinum Ellis & Arthur at 50 microg ml(-1) and 30 microg ml(-1), respectively. Kakuol and a derivative analogue are able to inhibit the DNA relaxation mediated by the human enzyme. |
| CFN96195 | Zarzissine Zarzissine exhibits cytotoxicity against three human and murine tumor cell lines. |
| CFN96196 | Lanatoside C Lanatoside C, a cardiac glycoside, possesses the ability to inhibit the interchange of Na and K across cell membrane and is widely used to treat anti-arrhythmias and heart failure. Lanatoside C can effectively inhibit all four serotypes of dengue virus, flavivirus Kunjin, alphavirus Chikungunya and Sindbis virus as well as the human enterovirus 71, suggest that lanatoside C possesses broad spectrum antiviral activity against several groups of positive-sense RNA viruses. |
| CFN96197 | Isorhynchophylline Isorhynchophylline exerts anti-inflammatory, anticancer and anti-metastatic effects, it exerts neuroprotective effect against Aβ 25-35-induced neurotoxicity in vitro via PI3K/Akt signaling pathway. Isorhynchophylline shows antidepressant-like effects, which are mediated, at least in part, by the inhibition of monoamine oxidases. Isorhynchophylline plays a remarkably preventive role in cardiac arrhythmias through the inhibition of calcium currents in rats and guinea pigs; it also shows inhibition on angiotensin II-induced proliferation in rat vascular smooth muscle cells. |
| CFN96198 | 8-Methyleugenitol 8-Methyleugenitol is a natural product from Lysimachia foenumgraecum. |
| CFN96199 | Isodorsmanin A Reference standards. |
