Natural Products
| Catalog No. | Information |
| CFN96005 | O-Methylpallidine Standard reference |
| CFN96006 | Royleanone Royleanone possesses cytotoxic activity against the human pancreatic cancer cell line MIA PaCa-2. |
| CFN96007 | Dodoviscin H Dodoviscin H can promote adipocyte differentiation as characterized by increased triglyceride levels in 3T3L1 cells. |
| CFN96008 | Aliarin Aliarin is a natural product from Dodonaea viscosa. |
| CFN96009 | 4,5-Diepipsidial A Reference standards. |
| CFN96010 | Haplopine Haplopine shows photo-activated antimicrobial activity against S. aureus. It exhibits potent melanogenesis-inhibitory activities with almost no toxicity to the cells. |
| CFN90562 | Bryonolol Reference standards. |
| CFN90563 | Karounidiol Karounidiol exhibits cytotoxicity especially against a human renal cancer, it markedly suppresses the promoting effect of TPA (1 microgram/mouse) on skin tumor formation in mice following initiation with 7,12-dimethylbenz[a]anthracene (50 micrograms/mouse). |
| CFN90564 | (20S)-Protopanaxatriol (20S)-Protopanaxatriol is a metabolite of ginsenoside, works through the glucocorticoid receptor (GR) and oestrogen receptor (ER), and is also a LXRα inhibitor. (20S)-Protopanaxatriol shows strong and selective antimicrobial activity, it also has anti-oxidant activity. (20S)-Protopanaxatriol exerts cardioprotective effects against myocardial ischemic injury, by enhancing the anti-free-radical actions of heart tissues. |
| CFN90565 | Ginsenoside Rg6 Ginsenoside Rg6 can inhibit JK cell proliferation in human lymphocytoma and induce its apoptosis, the mechanism may through mitochondrial dysfunction and an increase of Bax expression and decrease of Bcl-2 expression. |
| CFN90566 | 7-Methoxycoumarin 7-Methoxycoumarin, also known as Herniarin, has potent antioxidant, hepatoprotective, and antitumor effects. 7-Methoxycoumarin has a weak estrogenic activity in vitro and in vivo, it could be beneficial with regard to vagina dryness as it showed a tissue specific effect without exposing the uterus to a potential tumorigenic growth. |
| CFN96011 | p-Coumaryl alcohol p-Coumaryl alcohol derivatives have antioxidant activity. |
| CFN96012 | Sventenic acid Standard reference |
| CFN96013 | Aristolactam AII Aristolactam AII has cytotoxic activity, it also shows platelet aggregation inhibitory activity. |
| CFN96014 | 3-Methylcatechol 3-Methylcatechol is a natural product from Phellinus igniarius. |
| CFN96015 | Dodoviscin I Dodoviscin I can promote adipocyte differentiation as characterized by increased triglyceride levels in 3T3L1 cells. |
| CFN96016 | Dodoviscin A Dodoviscin A may be a new promising pigmentation-altering agent for cosmetic and therapeutic applications, it can inhibit melanin biosynthesis induced by 3-isobutyl-1-methylxanthine and PD98059.Dodoviscin A can promote adipocyte differentiation as characterized by increased triglyceride levels in 3T3L1 cells, it can enhance the accumulation of lipid droplets and induce upregulation of the expression of the adipocyte-specific genes aP2 and GLUT4. |
| CFN96017 | Camaldulenic acid Standard reference |
| CFN96018 | Gelsempervine A Gelsempervine A is a natural product from Gelsemium elegans. |
| CFN96019 | Palbinone Palbinone can induce HO-1 expression in the hepatic cells. It shows a strong inhibitory activity on the reduced form of nicotinamide adenine dinucleotide phosphate (NADPH)-linked 3 alpha-hydroxysteroid dehydrogenase (3 alpha-HSD) of rat liver cytosol. |
| CFN90567 | 7-Ethoxycoumarin The oxidation of 7-Ethoxycoumarin, a typical human P450 substrate, is catalyzed by both wild-type and mutant forms of CYP102A1. |
| CFN96020 | 9-Deoxygoniopypyrone 9-Deoxygoniopypyrone shows significant cytotoxicity against human tumor cells. |
| CFN96021 | Procumbide Procumbide has anti-inflammatory activity. |
| CFN96022 | Paeoniflorigenone Paeoniflorigenone is a depolarizing neuromuscular blocking agent, being similar to succinylcholine.Paeoniflorigenone is cytotoxic and induces apoptosis selectively in the cancer cell lines. Paeoniflorigenone shows anti-inflammatory effects, it may take part in improving blood circulation by inhibiting ether platelet aggregation and/or blood coagulation. |
| CFN96023 | Hesperetin 5-O-glucoside Hesperetin 5-O-glucoside has hypocholesterolemic effect. |
| CFN96024 | Cristacarpin Cristacarpin exhibits moderate but selective activity towards DNA repair-deficient yeast mutants. It promotes endoplasmic reticulum (ER) stress, leading to sub-lethal reactive oxygen species (ROS) generation and which eventually terminates by triggering senescence in pancreatic and breast cancer cells through blocking the cell cycle in the G1 phase. |
| CFN96025 | Obtucarbamate A Obtucarbamate A has antitussive activity, it exhibits significant inhibitory effect against neuroinflammation with the IC50 value of 10.57 uM . |
| CFN96026 | Obtucarbamate B Obtucarbamate B has antitussive activity. |
| CFN96027 | Falcarinol Falcarinol has effects on CaCo-2 cells appear to be biphasic, inducing pro-proliferative and apoptotic characteristics at low and high concentrations of Falcarinol, respectively. Falcarinol-associated dermatitis is due to antagonism of the CB(1) receptor in keratinocytes, leading to increased chemokine expression and aggravation of histamine action. |
| CFN96028 | 6alpha-Hydroxycleroda-3,13-dien-16,15-olid-18-oic acid (-)-6β-Hydroxy-5β,8β,9β,10α-cleroda-3,13-dien-16,15-olid-18-oic acid is one alpha- glucosidase inhibitory constituent from Duranta repens. |
| CFN96029 | 6alpha-Hydroxymedicarpin Reference standards. |
| CFN96030 | 16-Epivoacarpine 16-Epivoacarpine is a natural product from Gelsemium elegans. |
| CFN90568 | Isorhamnetin 3-glucuronide Isorhamnetin 3 -O -glucuronide exerts anti-inflammatory activity by increasing heme oxygenase-1 (HO-1) expression and by suppressing Jun N-terminal kinase (JNK) and p38 signaling pathways in LPS-challenged RAW264.7 macrophage cells. Isorhamnetin 3-glucuronide can inhibit vascular cell adhesion molecule-1 (VCAM-1) cell surface expression at 2 micromol/L, indicates that it can inhibit the expression of key molecules involved in monocyte recruitment during the early stages of atherosclerosis at physiological concentrations. It (1 mg/kg i.v.) can progressively reduce mean blood pressure (MBP), measured in conscious spontaneously hypertensive rats (SHR). |
| CFN90569 | Tranexamic acid Tranexamic acid is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM. Tranexamic acid appears to be a promising drug for the prevention and treatment of PPH after both vaginal and caesarean delivery, it can reduce mortality due to traumatic bleeding by a third, without apparent safety issues. |
| CFN90570 | Selinidin Selinidin decreases phosphorylation of phospholipase C-gamma1, p38 mitogen-activated protein kinase, and IkappaB-alpha upon FcepsilonRI stimulation. |
| CFN96031 | Kuwanol C Kuwanol C is a natural product from Morus alba L. |
| CFN96032 | Cuspidiol Cuspidiol shows cytotoxicity against Jurkat T cell clone E6.1 at 7.3 ug/mL. |
| CFN96033 | 16-Nor-15-oxodehydroabietic acid 16-Nor-15-oxodehydroabietic acid is a natural product from Pinus massoniana. |
| CFN96034 | Maoyerabdosin Standard reference |
| CFN96035 | Dodoviscin J Dodoviscin J can promote adipocyte differentiation as characterized by increased triglyceride levels in 3T3L1 cells. |
| CFN96036 | 1-Methoxyindole-3-carboxylic acid Standard reference |
| CFN96037 | 6alpha-Hydroxymaackiain 6alpha-Hydroxymaackiain is a natural product from Derris robusta. |
| CFN96038 | 7-O-Methylporiol Reference standards. |
| CFN90571 | Chiisanoside Chiisanoside has anti-oxidant, anti-inflammatory, anti-rotaviral activities, it can inhibit xanthine oxidase activity and increase superoxide dismutase (SOD), glutathione peroxidase and catalase, it also inhibits NO and PGE2 production. Chiisanoside has the potential to prevent obesity as a lipase inhibitor which suppresses fat absorption in vivo. |
| CFN96039 | 1,2-Methylenedioxy-3,10,11-trimethoxynoraporphine 1,2-Methylenedioxy-3,10,11-trimethoxyaporphine exerts moderate vessel-relaxing activities with the IC 50 value from 16.50 to 32.81 microM at the test concentrations. |
| CFN96040 | Coumestrol Coumestrol is a novel inducer of mitochondrial biogenesis through the activation of Sirt1, it suppresses the accumulation of HIF-1α via suppression of SPHK1 pathway in hypoxic PC-3 cells. Coumestrol can function by inhibiting oncogenic disease, at least in part, through CKII inhibition-mediated cellular senescence. Coumestrol treatment is effective in preventing neuronal loss in all times of administration as well as able to rescue the Na+, K+ -ATPase activity, suggesting its potential benefits for either prevention or therapeutics use against cerebral ischemia in males. |
| CFN96041 | Cepharadione A Cepharadione A is a naturally occurring DNA damaging agent. |
| CFN96042 | 5,7,4'-Tri-O-methylcatechin Reference standards. |
| CFN96043 | 3-O-p-Coumaroyloleanolic acid Reference standards. |
| CFN96044 | Ginsenoyne K Ginsenoyne K shows dose-dependent inhibitory effect on dopa oxidase activity of tyrosinase. |
