Natural Products
| Catalog No. | Information |
| CFN96307 | Wallichinine Wallichinine shows inhibitory activity on platelet aggregation caused by platelet activating factor (PAF). Wallichinine with ABCB1 presents valuable clues for the development of novel MDR reversal reagents from natural products, wallichinine can significantly potentiate the effects of two ABCB1 substrates vincristine and doxorubicin on inhibition of growth, arrest of cell cycle and induction of apoptosis in ABCB1 overexpressing cancer cells, and the overexpression of ABCB1 in cancer cells is one of the main reasons of cancer multidrug resistance (MDR). |
| CFN96308 | Kadsurenin D Reference standards. |
| CFN96309 | Aglain C Reference standards. |
| CFN96310 | erythro-Guaiacylglycerol beta-sinapyl ether Standard reference |
| CFN96311 | (2S)-2alpha-(1,3-Benzodioxol-5-yl)-3,5-dihydro-5alpha-methoxy-3beta-methyl-5-allyl-2H-benzofuran-6-one Reference standards. |
| CFN96312 | ent-16alpha,17-Dihydroxyatisan-3-one ent-16alpha,17-Dihydroxyatisan-3-one and ent-16alpha,17-dihydroxykauran-3-one have apoptosis induction activities on L5178 human MDR1 gene-transfected mouse lymphoma cells. |
| CFN96313 | Denudadione C Reference standards. |
| CFN96314 | Octadecyl caffeate z-Octadecyl caffeate may have pain-relieving activity. Octadecyl caffeate and coptisonine can stimulate glucose uptake at 25 and 50 ug/mL. Octadecyl caffeate and octadecyl coumarate applied to the surface of susceptible varieties in laboratory bioassays reduced feeding and oviposition, as observed on roots of resistant varieties, and therefore are implicated in weevil resistance. |
| CFN96315 | 3'',4''-Di-O-acetyl-2'',6''-di-O-p-coumaroylastragalin Reference standards. |
| CFN96316 | Torilin Torilin is an inhibitor of testosterone 5 alpha-reductase, it (IC50 = 31.7 +/- 4.23 microM) shows a stronger inhibition of 5 alpha-reductase than alpha-linolenic acid (IC50 = 160.3 +/- 24.62 microM) but is weaker than finasteride (IC50 = 0.38 +/- 0.06 microM). Torilin has immunomodulatory, hepatoprotective, and anti-inflammatory properties, it inhibits inflammation by limiting TAK1-mediated MAP kinase and NF-κB activation, it can attenuate arthritis severity, modify leukocyte activations in dLNs or joints, and restore serum and splenocyte cytokine imbalances. Torilin inhibits melanin production in alpha-melanocyte stimulating hormone-activated B16 melanoma cells, with an IC(50) value of 25 microM. Torilin shows excellent antimicrobial activity against Bacillus subtilis ATCC 6633 spores and vegetative cells. Torilin has a potent anti-angiogenic activity both in vivo and in vitro, and it may have a strong activity to suppress tumorigenesis by inhibition of tumor invasion, it reverses multidrug-resistance in cancer cells, it can potentiate the cytotoxicities of adriamycin, vinblastine, taxol and colchicine against multidrug-resistant KB-V1 and MCF7/ADR cells. |
| CFN96317 | Borapetoside D Standard reference |
| CFN96318 | Shizukanolide F Standard reference |
| CFN96319 | 12-Demethylneocaesalpin F Reference standards. |
| CFN96320 | Chloramultilide B Chloramultilide B exhibits moderate in vitro antifungal activity. |
| CFN96321 | Perilloxin Perilloxin possesses inhibitory activities against cyclooxygenase-1,with IC(50) values of 23.2 microM. |
| CFN96322 | Isokadsurenin D Standard reference |
| CFN96323 | Dihydrosesamin Standard reference |
| CFN96324 | Corymbol Reference standards. |
| CFN96325 | Chloramultilide C Standard reference |
| CFN96326 | Guaiol (-)-Guaiol is a biocatalyst. Guaiol has insecticidal activity. |
| CFN96327 | Ophiopogonanone C Standard reference |
| CFN96328 | Sarcandrolide D Reference standards. |
| CFN96329 | Conquinamine Standard reference |
| CFN96330 | Scoulerine Scoulerine shows significant cytotoxic effects against both two cancer cell lines (Caco-2 and Hep-G2 cancer cells), with IC50 values 6.44 ± 0.87 and 4.57 ± 0.42, respectively. It shows antiplasmodial activity with IC(50) values of 5.4uM and 3.1uM against the antifolate sensitive and the multidrug resistant P. falciparum strains: TM4/8.2 and K1CB1, respectively. |
| CFN96331 | ent-16-Kaurene-3beta,15beta,18-triol ent-16-Kaurene-3beta,15beta,18-triol, ent-16-kaurene-3beta,15beta-diol,abbeokutone,and helioscopinolide A possess appreciable anti-allergic activities in RBL-2H3 cells model with IC50 values ranging from 22.5 to 42.2 microM. |
| CFN96332 | Ophiopogonanone E Ophiopogonanone E has oxygen free radicals(OFRs) scavenging effects, it can scavenge hydroxyl radical(·OH) and hydrogen peroxide(H2O2) in vitro. |
| CFN96333 | ent-Atisane-3beta,16alpha,17-triol Standard reference |
| CFN96334 | 4-Hydroxy-11,12,13-trinor-5-eudesmen-7-one Reference standards. |
| CFN96335 | Beta-Rotunol Standard reference |
| CFN96336 | 6-Aldehydo-isoophiopogonone A Standard reference |
| CFN96337 | Ophiopogonanone A Ophiopogonanone A has oxygen free radicals(OFRs) scavenging effects, it can scavenge hydroxyl radical(·OH) and hydrogen peroxide(H2O2) in vitro. |
| CFN96338 | Ophiopogonanone F Ophiopogonanone F can be used for preparing a drug for resisting hepatocellular injury. |
| CFN96339 | 5,7-Dihydroxy-3-(4-hydroxy-3,5-dimethoxybenzyl)-6,8-dimethylchroman-4-one 5,7-Dihydroxy-3-(4-hydroxy-3,5-dimethoxybenzyl)-6,8-dimethylchroman-4-one has oxygen free radicals(OFRs) scavenging effects, it can scavenge hydroxyl radical(·OH) and hydrogen peroxide(H2O2) in vitro.It shows a strong cytotoxic activity on HeLa-S3 cell. |
| CFN96340 | (-)-Corlumine Corlumine exhibits spasmolytic and GABA antagonist activity. |
| CFN96341 | Euphroside Standard reference |
| CFN96342 | 3-(2,4-Dihydroxybenzyl)-5-hydroxy-7,8-dimethoxy-6-methylchroman-4-one Reference standards. |
| CFN96343 | Beta-Peltoboykinolic acid Beta-Peltoboykinolic acid has in vitro protein tyrosine phosphatase 1B (PTP1B) inhibitory, it inhibits PTP1B with IC50 values of 5.2+/-0.5 microM. It also has cytotoxic activity. |
| CFN96344 | Aglain B Standard reference |
| CFN96345 | 11-O-Galloylbergenin 11-O-Galloylbergenin shows good antioxidant and antiplasmodial activities, it shows significant analgesic activity at doses of 20 and 40 mg/kg against formalin test in rats, and it exhibits significant anti-inflammatory activity in carrageenan-induced paw edema model at doses of 10, 20 and 30 mg/kg.11-O-Galloylbergenin shows significant urease inhibitory potential with IC50 value of 38.6±1.5 uM. |
| CFN96346 | Ligucyperonol Ligucyperonol exhibits significant activities on protecting muscle cells from mild to moderate oxidative stress. |
| CFN96347 | Gelomuloside A Standard reference |
| CFN96348 | Gelomuloside B Reference standards. |
| CFN96349 | Gelomulide N Reference standards. |
| CFN96350 | 20-Deoxyingenol 3-angelate 20-Deoxyingenol 3-angelate and ingenol 20-acetate 3-angelate are known as promoters of tumors of mouse skin. 20-Deoxyingenol 3-angelate can induce significant platelet aggregation accompanied by induction of phosphorylation of PKC substrates in platelets, it is a protein kinase C (PKC) activator. |
| CFN96351 | 4-O-Galloylbergenin 4-O-Galloylbergenin shows significant 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scavenging activity with EC₅₀ 7.8 uM, it shows more antioxidant activity than the positive control vitamin C (EC₅₀ = 28.3 uM). |
| CFN96352 | Longipedlactone J Standard reference |
| CFN96353 | 2',4'-Dihydroxy-3,7':4,8'-diepoxylign-7-ene Reference standards. |
| CFN96354 | Acantrifoside E Standard reference |
| CFN96355 | Splendoside Standard reference |
| CFN96356 | Glutathione Glutathione plays important roles in antioxidant defense, nutrient metabolism, and regulation of cellular events (including gene expression, DNA and protein synthesis, cell proliferation and apoptosis, signal transduction, cytokine production and immune response, and protein glutathionylation); glutathione deficiency contributes to oxidative stress, which plays a key role in aging and the pathogenesis of many diseases (including kwashiorkor, seizure, Alzheimer's disease, Parkinson's disease, liver disease, cystic fibrosis, sickle cell anemia, HIV, AIDS, cancer, heart attack, stroke, and diabetes). |
