Natural Products
| Catalog No. | Information |
| CFN94819 | Pulchinenoside B Pulchinenoside B is a natural product from Pulsatilla chinensis (Bge.) Regel. |
| CFN94832 | Raddeanoside R8 Raddeanoside R8 is a natural product from Anemone raddeana Regel. |
| CFN95009 | 6-Hydroxywogonin |
| CFN96258 | Isovouacapenol C Standard reference |
| CFN96259 | trans-Methylisoeugenol (E)-Methyl isoeugenol (trans-Methylisoeugenol) is a natural food flavour, it also has anxiolytic and antidepressant like properties. Eugenol methyl ether(trans-Methylisoeugenol) can cause moderate reversible inhibition of glutathione S-transferases (GSTs)(I25 ranged from 0.2 to 5.4 mM for human GSTs and from 0.4 to 4.9 mM for rat GSTs).The use of isoeugenol methyl ether(trans-Methylisoeugenol) is described as an agent to inhibit and/or prevent the growth of and/or to destroy micro-organisms causing bad breath and/or to combat bad breath. |
| CFN96260 | Fargesone B Fargesone B inhibits the vascular smooth muscle contraction by suppressing the voltage- and receptor-activated calcium influxes in a nonselective manner. |
| CFN96261 | 2''-O-Coumaroyljuglanin Reference standards. |
| CFN96262 | Mearnsetin Mearnsetin and myricetin have antioxidant activity. |
| CFN96263 | Edgeworin Edgeworin is a DNA polymerase beta (pol beta) inhibitor, it inhibits both the lyase and polymerase activities of DNA polymerase beta; it can potentiate the inhibitory action of the anticancer drug bleomycin in cultured A549 cells via an inhibition of DNA repair synthesis. |
| CFN96264 | Methyleugenolglycol Reference standards. |
| CFN96265 | 16-Deoxysaikogenin F Reference standards. |
| CFN96266 | Eudesmin Eudesmin shows antiinflammatory, neuritogenic, anticonvulsant and sedative effects, the mechanism of eudesmin may be related to up-regulation of GABAA and GAD65 expressions, and anti-apoptosis of neuron the in brain.50 microM (+)-eudesmin can induce neurite outgrowth and enhance nerve growth factor (NGF)-mediated neurite outgrowth from PC12 cells by stimulating up-stream MAPK, PKC and PKA pathways. |
| CFN96267 | Neolinine Neolinine(at 10uM) shows significant hERG K+ channel inhibition activity. |
| CFN96268 | 3,4-Dimethoxybenzamide Standard reference |
| CFN96269 | Puerol A Puerol A exhibits potent inhibitory effects on aldose reductase with IC50 values of 6.4 uM. dl-Puerol A has antioxdiant activity, it shows inhibitory effects on copper ion-induced protein oxidative modification of mouse brain homogenate in vitro. |
| CFN96270 | Cycloshizukaol A Cycloshizukaol A prevents monocyte adhesion to HUVEC through the inhibition of cell adhesion molecules expression stimulated by TNF-alpha, it inhibits PMA-induced homotypic aggregation of HL-60 cells without cytotoxicity with MIC values of 0.9 microM. |
| CFN96271 | Norglaucine hydrochloride (+)-Norglaucine shows cytotoxic activity toward the tumor cell lines B16-F10 (mouse melanoma), HepG2 (human hepatocellular carcinoma), K562 (human chronic myelocytic leukemia) and HL-60 (human promyelocytic leukemia) and non-tumor peripheral blood mononuclear cells (PBMCs). |
| CFN96272 | 1-Hydroxy-2,3,5-trimethoxyxanthone 1-Hydroxy-2,3,5-trimethoxyxanthone (HM-1) has vasodilator action ,which involves both an endothelium-dependent mechanism involving NO and an endothelium-independent mechanism by inhibiting Ca(2+) influx through L-type voltage-operated Ca(2+) channels; a minor contribution to the effects of HM-1 may be related to inhibition of the protein kinase C-mediated release of intracellular Ca(2+) stores. HM-1,at the concentration of 1 ug/mL, can effectively inhibit the osteoclast differentiation in a co-culture system with mouse osteoblastic calvarial cells and bone marrow cells; it also can protect mice from the acute lung injury induced by ipopolysaccharide (LPS), which is relative to the increasing of IκB-α protein expression and the suppressing of inducible nitric oxide synthase and cyclooxygenase-Ⅱ protein expression. |
| CFN96273 | Shizukanolide C Standard reference |
| CFN96274 | Borapetoside E Borapetoside E has anti-hyperglycemic activity, it can significantly reduce serum glucose levels at dose-dependent manners in alloxan-induced hyperglycemic mice and db/db type 2 diabetic mice. |
| CFN96275 | 1-(3,4-Dihydroxyphenyl)-7-(4-hydroxyphenyl)heptane-3,5-diyl diacetate Reference standards. |
| CFN96276 | 6-Deoxyjacareubin 6-Deoxyjacareubin possesses significant antioxidant activities, it also exhibits the cytotoxic activities against HL-60, SMMC-7721, A-549, MCF-7, and SW-480 cell lines.6-Deoxyjacareubin is antifungal against Cladosporium cucumerinum, while it shows differing degrees of inhibition of monoamine oxidase A and B. 6-Deoxyjacareubin shows strong platelet activating factor (PAF) receptor binding inhibitory effects using rabbit platelets with IC50 values of 29.0 microM, suggests that xanthones can represent a new class of natural PAF receptor antagonists. |
| CFN96277 | Orsellinic acid Orsellinic acid is a novel benzoquinone ring precursor for antroquinonol and 4-acetylantroquinonol B, it formed from acetyl-coenzyme Q (CoQ) and malonyl-CoA via polyketide pathway. Orsellinic acid can block platelet activating factor (PAF)-mediated neuronal apoptosis without affecting G-protein coupled receptor (PAFR)-mediated neuroprotection, it can effectively attenuate PAFR-independent neuronal apoptosis. |
| CFN96278 | 5-Hydroxy-1-methoxyxanthone 5-Hydroxy-1-methoxyxanthone, 1,5-dihydroxyxanthone and 6-deoxyjacareubin are all antifungal against Cladosporium cucumerinum, while they show differing degrees of inhibition of monoamine oxidase A and B. |
| CFN96279 | Borapetoside F Standard reference |
| CFN96280 | 8-Epideoxyloganic acid 8-Epideoxyloganic acid possesses bioactivities of analgesia, homeostasis and anti-inflammatory. It has the potential to serve as anti-inflammatory agents during oxidative stress, the inhibition of ROS production, possibly through modulation of NOX activity and/or the radical scavenging effect, and beta2 integrin expression in leucocytes. 8-Epideoxyloganic acid (oral) shows weak antinociceptive activity. |
| CFN96281 | Farrerol 7-O-glucoside Reference standards. |
| CFN96282 | Sanshodiol Standard reference |
| CFN96283 | Piperenone Piperenone is an insect antifeeding substance. It has anti-platelet-activating factor(PAF) activities, is a PAF-acether antagonist. |
| CFN96284 | Xanthoxyletin Xanthoxyletin shows potent antibacterial, fungicidal, and algicidal properties, it also has anticancer, and anti-inflammatory activities. It shows an inhibitory effect on iNOS protein expression at 10 microM, it also can inhibit the synthesis of nitric oxide and the protein expression of tumor necrosis factor-alpha and cyclooxygenase-2. Xanthoxyletin induces S phase arrest and apoptosis in human gastric adenocarcinoma SGC-7901 cells, the effects are associated with the DNA damage, apoptosis through mitochondrial dysfunction, and cell cycle arrest at S phase in a dose-dependent manner, it also can increase the production of reactive oxygen species. |
| CFN96285 | Gelomulide A Standard reference |
| CFN96286 | Mirandin B Standard reference |
| CFN96287 | Gopherenediol Gopherenediol shows weak antifeedant activity. |
| CFN96288 | Mesuol Mesuol has antioxidant activity, it shows very high scavenging activity against DPPH radical; it also has immunomodulatory activity, can potentiate percentage neutrophil adhesion in neutrophil adhesion test in rats and phagocytosis in carbon clearance assay. Mesuol can suppress HIV-1 replication in Jurkat T cells, it inhibits TNFα-induced HIV-1-LTR transcriptional activity by targeting the nuclear factor-κB (NF-κB) pathway. |
| CFN96289 | 1,6-Dihydro-4,7'-epoxy-1-methoxy-3',4'-methylenedioxy-6-oxo-3,8'-lignan Reference standards. |
| CFN96290 | 1-Methyl-2-nonylquinolin-4(1H)-one 1-Methyl-2-nonylquinolin-4(1H)-one has anti-inflammatory activity, it exhibits inhibitory activity on leukotriene biosynthesis in a bioassay using human polymorphonuclear granulocytes, with IC50 values of 12.1 microM. |
| CFN96291 | 5-Hydroxy-1,7-bis(4-hydroxyphenyl)heptan-3-yl acetate Reference standards. |
| CFN96292 | Kaempferol 5,7,4'-trimethyl ether Reference standards. |
| CFN96293 | Gelomulide B Reference standards. |
| CFN96294 | 3(20)-Phytene-1,2-diol Standard reference |
| CFN96295 | Quinamine Standard reference |
| CFN96296 | 1-Methyl-2-undecylquinolin-4(1H)-one 1-Methyl-2-undecyl-4(1H)-quinolone, and dihydroevocarpine should also be served as the chemical markers together with evodiamine for the quality control of Evodia rutaecarpa (Juss.) Benth. 1-Methyl-2-undecyl-4(1H)-quinolone shows a selective inhibition of type B MAO (MAO-B) activity with the IC(50) value of 15.3 microM using a substrate kynuramine, but does not inhibit type A MAO (MAO-A) activity.It can mitigate high phosphate-induced human aortic valve interstitial cells (HAVICs) calcification by inhibiting phosphate cotransporter (PiT-1) gene expression. It also shows moderate antiangiogenic activity against human tumor cells. |
| CFN96297 | 3,5,7,15-Tetraacetoxy-9-nicotinoyloxy-6(17),11-jatrophadien-14-one Standard reference |
| CFN96298 | Borapetoside B Standard reference |
| CFN96299 | Aglaxiflorin D Standard reference |
| CFN96300 | Yucalexin P-17 Standard reference |
| CFN96301 | erythro-1-Phenylpropane-1,2-diol Reference standards. |
| CFN96302 | 1,7-Bis(4-hydroxyphenyl)hept-6-en-3-one Reference standards. |
| CFN96303 | Rabdoketone B Reference standards. |
| CFN96304 | 10-O-Methylprotosappanin B Standard reference |
