Natural Products
| Catalog No. | Information |
| CFN91943 | (R)-Eriodictyol-8-C-beta-D-glucopyranoside Reference standards. |
| CFN91942 | Eriodictyol-8-glucoside Reference standards. |
| CFN91941 | 5,7-dimethoxy-2,2-dimethylchromene 5,7-Dimethoxy-2,2-dimethylchromene is a potential inhibitor of juvenile hormone onLocusta migratoria. |
| CFN91940 | 5'-Methoxynobiletin 5'-Methoxynobiletin may exhibit antinociceptive and anti-inflammatory activities in both formalin phases. |
| CFN91939 | Desoxypeganine Desoxypeganine is a cholinesterase inhibitor, acting preferentially on butyrylcholinesterase, and as a selective inhibitor of monoamine oxidase A but not monoamine oxidase B.Desoxypeganine is being developed for its potential utility in the pharmacological treatment of alcohol abuse to reduce craving and depression in alcohol abusers, and might also be useful as a smoking cessation aid. |
| CFN91938 | 4-Quinazolinone Some 4-quinazolinone derivatives have antiplatelet activity. |
| CFN91937 | Harmalacidine Harmalacidine exhibits cytotoxicity against U-937 cells with IC50 value of 3.1 ± 0.2 μmol/L, the mechanism is targeting the mitochondrial and protein tyrosine kinase signaling pathways (PTKs-Ras/Raf/ERK). |
| CFN91936 | Pseudoneolinderane Reference standards. |
| CFN91935 | Denudaquinol Denudaquinol shows cytotoxicity against the SFME and r/mHM-SFME-1 cell lines. |
| CFN90999 | Angelol A Angelol A and angelol B are passive diffusion as the dominating process in Caco-2 cell monolayer model. |
| CFN91000 | Angelol B The absorption and transport of angelol A and Angelol B are passive diffusion as the dominating process in Caco-2 cell monolayer model. |
| CFN91934 | Lettowienolide Lettowienolide exhibits mild in vitro activity against the Plasmodium falciparum malaria parasite ( IC(50) approximately 20 microg/mL). |
| CFN91933 | Strychnistenolide Reference standards. |
| CFN91932 | Kamebakaurin Kamebakaurin has anti-cancer and anti-inflammatory activities through direct inhibition of DNA-binding activity of nuclear factor-kappa B (NF-κB) p50; it has anti-neuroinflammatory activity via inhibition of c-Jun NH₂-terminal kinase and p38 mitogen-activated protein kinase pathway in activated microglial cells. Kamebakaurin inhibits the expression of hypoxia-inducible factor-1α and its target genes to confer antitumor activity. Kamebakaurin also has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. |
| CFN91931 | Rabdoserrin A Reference standards. |
| CFN91930 | Linderene acetate Linderene acetate is a competitive inhibitor against Prolyl endopeptidase. |
| CFN91929 | Aurantiamide benzoate Aurantiamide benzoate exhibits moderate inhibitory activity against xanthine oxidase. |
| CFN91928 | 5-O-beta-D-Glucopyranosylmyricanol Reference standards. |
| CFN91927 | Rubiyunnanin C Rubiyunnanin C exhibits cytotoxic activities against a panel of eleven cancer cell lines and exerts inhibitory activities against nitric oxide (NO) production in LPS and IFN-γ-induced RAW 264.7 murine macrophages. |
| CFN91926 | 12-Hydroxymyricanone 12-Hydroxymyricanone exhibits anti-tubercular activity against Mycobacterium tuberculosis H37Rv in vitro and the MIC value of 35.8 ug/mL. It inhibits the release of nitric oxide with the IC(50) value of 30.19 muM. |
| CFN91925 | Angelol H Angelol H is a natural product from Angelica sinensis. |
| CFN91924 | Pseudolarifuroic acid Pseudolarifuroic acid is a natural product from Pseudolarix kamepferi. |
| CFN91923 | 16,17-Dihydroapovincamine Reference standards. |
| CFN91922 | Mesopsin Mesopsin has antioxidant activity. |
| CFN91921 | 12-Hydroxyganoderic acid D Reference standards. |
| CFN91920 | Salannin Salannin has antifeedant and insect growth-regulating activities.Salannin also has anti-inflammatory activity,it exerts moderate inhibition (IC(50) values of 410-471 mol ratio/32 pmol TPA) of TPA-induced Epstein-Barr virus early antigen (EBV-EA) activation in Raji cells. Salannin inhibits ecdysone 20-monooxygenase (E-20-M) activity in a dose-dependent fashion. |
| CFN91919 | Nimbolide Nimbolide is a more potent antiproliferative and apoptosis inducing agent and offers promise as a candidate agent in multitargeted prevention and treatment of cancer; it can sensitize tumor cells to chemotherapeutic agents through interaction with IKK, leading to inhibition of NF-κB-regulated proteins. Nimbolide attenuates the lipid accumulation, oxidative stress and antioxidant in primary hepatocytes. Nimbolide also has antibacterial potential. |
| CFN91918 | 6-Oxo-23-norpristimerol Reference standards. |
| CFN91917 | Triptobenzene K Reference standards. |
| CFN91916 | Blepharotriol Blepharotriol may have antimicrobial and cytotoxic activities. |
| CFN91915 | Zeylasterone Zeylasterone shows bactericidal activity. |
| CFN91914 | Wilforol E Reference standards. |
| CFN91913 | Neotriptophenolide Reference standards. |
| CFN91912 | Triptohairic acid Reference standards. |
| CFN91911 | Dihydropyrocurzerenone Reference standards. |
| CFN91910 | Magnoloside D Magnoloside D shows moderate cytotoxicity against MGC-803 and HepG2 cells. Magnoloside D also shows potent antioxidant capacity. |
| CFN91909 | Podophyllotoxinone Podophyllotoxinone shows inhibitory activity against L1210 leukemia and KB cells in vitro. |
| CFN91908 | Podophyllotoxin 4-O-glucoside Reference standards. |
| CFN91907 | Diphyllin O-glucoside Reference standards. |
| CFN91906 | Diphyllin Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling. Diphyllin has anti-inflammatory activities, it shows 50% inhibition of NO production from peritoneal macrophages. Diphyllin also has in vitro antileishmanial activity, it exerts a strong specific inhibitory activity (IC50 = 0.2 microM) resulting from the inhibition of parasite internalization within macrophages. |
| CFN91905 | Cudraflavone B Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in human gastric carcinoma cells and mouse melanoma cells, and hepatoprotective activity. It may be a lead for the development of a potential candidate for human oral squamous cell carcinoma cells. |
| CFN91904 | Shuterin Shuterin displays potent antioxidant activity. |
| CFN91903 | Montixanthone Reference standards. |
| CFN91902 | Gericudranin E Gericudranin E shows significant hepatoprotective effects with the EC50 value of 39.87+/-0.7 microM. |
| CFN91901 | Artocarpesin Artocarpesin has anti-inflammatory effects, it can suppress the LPS-induced production of nitric oxide (NO) and prostaglandin E 2 (PGE 2) through the down-regulation of inducible nitric oxide synthase (iNOS) and cyclooxygenase 2 (COX-2) protein expressions. Artocarpesin displays cytotoxic effects at various extent on all the 9 tested cancer cell lines with IC50 values respectively below 106 uM. Artocarpesin has interesting antimicrobial potency, and shows tyrosinase inhibitory activity. |
| CFN91900 | Hyperxanthone E Hyperxanthone E is a phytoalexin from Hypericum calycinum cell cultures. |
| CFN91899 | Helenalin Helenalin is a promising experimental cytotoxic agent that possibly points to new strategies to overcome apoptosis resistance attributable to overexpression of antiapoptotic Bcl-2 proteins. Helenalin is a new immunosuppressive compound suited for the treatment of deregulated and unwanted T cell-mediated immune responses. Helenalin has anti-inflammatory activity, it inhibits the transcription factor NF-kappaB by directly targeting p65. Helenalin has anti-trypanosomal activity against the African Trypanosoma brucei rhodesiense and American T. cruzi.; it reduces Staphylococcus aureus infection in vitro and in vivo. |
| CFN91898 | Delta-9-Tetrahydrocannabinol Delta 9-tetrahydrocannabinol(THC) induces dopamine release in the human striatum, this allows new directions in research on the effects of THC in neuropsychiatric disorders, such as schizophrenia. THC demonstrates an analgesic effect in patients experiencing cancer pain, it has antiemetic effect in patients receiving cancer chemotherapy. THC shows neuroprotection against ouabain-induced in vivo excitotoxicity, it promotes tumor growth by inhibiting antitumor immunity by a CB2 receptor-mediated, cytokine-dependent pathway. |
| CFN91897 | Gossypetin Gossypetin has anti-mutagenic, anti-atherosclerotic, antioxidant, as well as cytoprotective and antimicrobial effects, it inhibits bone resorption through down-regulating lysosomal cathepsin K activity and autophagy-related protein induction in actin ring-bearing osteoclasts. Gossypetin ameliorates ionizing radiation-induced oxidative stress in mice liver, it shows radioprotective action against gamma (γ)-radiation-induced oxidative stress. Gossypetin is an inducer of apoptotic and autophagic cell death in LNCaP cells, and provide a new mechanism for its anticancer activity. |
| CFN91896 | 23-epi-26-Deoxyactein 23-epi-26-Deoxyactein has anti-inflammatory activity, it inhibits nitric oxide production by reducing iNOS expression without affecting activity of the enzyme. It also has anti-cancer activity, it can inhibit growth of the MCF7 human breast cancer cells and induce cell cycle arrest at G1. |
