ChemFaces Product List

Catalog No.	Information
CFN80405	Hesperidin methylchalcone Hesperidin methylchalcone has anti-inflammatory effects, it can suppresse experimental gout arthritis in mice by inhibiting NF-κB activation. Hesperidin methylchalcone can regulate the expression of adhesion molecules in tumor necrosis factor-alpha-stimulated human umbilical vein endothelial cells. Hesperidin methylchalcone has a protective effect against leakage of FITC-dextran in the cheek pouch after administration of various permeability-increasing substances. It is a promising new therapeutic approach to protecting the skin from the deleterious effects of UVB irradiation.
CFN80437	Qingyangshengenin A Reference standards.
CFN80482	Escin IIB Escin IIB has positive effects on acute inflammation in animals, it can inhibit the induced by serotonin in rats, the hind paw edema induced by carrageenin, and the scratching behavior induced by compound 48/80 in mice. Escin IIB shows gastroprotection on ethanol-induced gastric mucosal lesions, whereas endogenous prostaglandins, NO, capsaicin-sensitive afferent neurons, and the sympathetic nervous system participate; it also enhances Mg(2+) absorption from the digestive tract in mice, in which the constitutive, but not the inducible, NO synthase plays an important role.
CFN80472	Pungiolide A Pungiolide A exhibits moderate cytotoxicities with IC50 values in the range of 0.90-6.84 uM.
CFN80402	Araloside VII Reference standards.
CFN80457	Kaempferol-4'-O-beta-D-glucopyranoside Kaempferol-4'-O-beta-D-glucopyranoside is an antihypertensive agent.
CFN80433	23S-hydroxy-11,15-dioxo-ganoderic acid DM Reference standards.
CFN80423	Oleanolic acid 3-O-beta-D-glucosyl-(1->3)-alpha-L-rhamnosyl(1->2)-alpha-L-arabinoside Reference standards.
CFN80438	Cytisine Hydrochloride Cytisine hydrochloride has toxicity.
CFN80100	Dencichine Dencichine is a neurotoxic agent, it is also a haemostatic agent, the hemostatic effect relates to modulation of coagulation system, platelet aggregation and fibrinolytic system. Dencichine has renoprotective effect, it could significantly prevent the progression of diabetic nephropathy possibly attribute to down-regulation of the TGF-β/Smad pathway and rebalance the deposition and degradation of ECM proteins.
CFN80104	3-hydroxymorindone Reference standards.
CFN80103	Glibenclamide Glibenclamide is a known blocker of vascular ATP-sensitive K+ channels (KATP), used in the treatment of type 2 diabetes.Glibenclamide increases the risk for hypoglycemia by increasing insulin secretion, it plays a paradoxical protective role to protect against severe hypoglycemia-induced fatal cardiac arrhythmias; it also reduces inflammation, vasogenic edema, and caspase-3 activation after subarachnoid hemorrhage.
CFN80110	Alpha-Terpineol Alpha-Terpineol has antitumour, anti-inflammatory, and antimicrobial activities, it inhibits the growth of tumour cells through a mechanism that involves inhibition of the NF-kappaB pathway; it can suppress the production of inflammatory mediators in LPS-stimulated human macrophages by interfering with the NF-kB, p38 or ERK MAPK pathways. Alpha-Terpineol may have utility as an anti-MRSA cleansing agent for dental instruments and dental unit chairs.
CFN80133	Methyl linoleate Methyl linoleate has antioxidant activity.
CFN80143	Decane Reference standards.
CFN80120	Marmesin angelate Reference standards.
CFN80126	Myricetin 3-O-beta-D-xylopyranosyl(1-2)-beta-D-glucopyranoside Reference standards.
CFN80156	Complanatoside B Reference standards.
CFN80136	Angelol K Angelol K shows significant activity on human platelet aggregation.
CFN80166	11-Deoxymogroside V Reference standards.
CFN80163	Myricetin 3-O-beta-D-glucopyranoside Myricetin 3-O-beta-D-glucopyranoside may have antioxidant, and anti-inflammatory activities.
CFN80148	Homomangiferin Homomangiferin has important medicinal properties and is widely used to relieve many symptoms, for example coughing and asthma.Homomangiferin shows antitumoural effects against MDA-MB-231 cells.
CFN80184	Pteroside A Reference standards.
CFN80051	Pterosin A Pterosin A is a novel activator of adenosine monophosphate-activated protein kinase, which is crucial for regulating blood glucose homeostasis. Pterosin A has potential anti-diabetic activity, it can significantly reverse the increased serum insulin and insulin resistance (IR) in dexamethasone-IR mice and in db/db mice.
CFN80185	Pterosin G Reference standards.
CFN80175	Laricitrin 3-O-glucoside Laricitrin 3-O-glucoside has antioxidant property.
CFN80213	Lucidin Lucidin and its derivatives are genotoxic, it is mutagenic at the hypoxanthine-guanine phosphoribosyl transferase gene locus.
CFN80270	Pipecolinic acid Pipecolic acid is a metabolite of lysine, it is a salivary metabolite biomarker.
CFN80224	3alpha-dihydrocadambine 3alpha-Dihydrocadambine exhibits dose-dependent hypotensive and anti-hypertensive effects in anesthetized normotensive rats and in conscious spontaneously hypertensive rats.
CFN80234	Sanguinarine chloride Sanguinarine chloride is a novel class of anti-Salmonella compounds, it could decrease the production of the SPI-1 type III secretion system main virulence proteins SipA and SipB and prevent the invasion of HeLa cells by Salmonella enterica serovar Typhimurium without affecting the growth of Salmonella. Sanguinarine chloride also shows cytotoxicity to cultured human cells from oral tissue.
CFN80241	Sodium taurochenodeoxycholate Sodium taurochenodeoxycholate can increase glucose-induced insulin secretion and stimulate the electrical activity of β-cells and enhance cytosolic Ca(2+) concentration ([Ca(2+)](c)).
CFN80242	Dulcitol Dulcitol has antitumor activity.
CFN80253	Senkyunolide Reference standards.
CFN80033	Acetagastrodin Acetagastrodin has antispasmodic effect on vascular smooth muscle. Acetagastrodin treatment may be an effective treatment to protect retinal neurons against such functional impairment during the early stages of diabetes.
CFN80062	Morin dihydrate Reference standards.
CFN80268	Epibrassinolide Brassinolide is a predominant plant growth modulator that regulate plant cell elongation. It is active against herpes and arena viruses.
CFN80005	Methacrylamide Methacrylamide has dyeing property.
CFN80461	Ganoderiol A Ganoderiol A suppresses migration and adhesion of MDA-MB-231 cells by inhibiting FAK-SRC-Paxillin cascade pathway.
CFN80061	Ptaquiloside Ptaquiloside shows genotoxicity, it also has carcinogenic effects. Ptaquiloside has immunosuppressive effects, it reduces NK cell activities by enhancing metallothionein expression, which is prevented by selenium.
CFN80330	Myricetin 3-O-beta-D-xylopyranosyl(1-2)-[alpha-L-rhamnopyranosyl-(1-6)]-beta-D-glucopyranoside Reference standards.
CFN80082	Tectorigenin sodium sulfonate Tectorigenin sodium sulfonate has antioxidant activity.
CFN80017	3-Hydroxy-2-methylpyridine 3-Hydroxy-2-methylpyridine could as a promising molecular scaffold for the future development of novel fibrillization inhibitors.
CFN80077	OJV-VI Reference standards.
CFN80078	(1beta,3beta,25S)-3-Hydroxyspirost-5-en-1-yl 2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-xylopyranoside Reference standards.
CFN80291	Pulchinenoside E Reference standards.
CFN80191	Heteroclitin D Heteroclitin D may be a valuable antitumor promoter or chemopreventor. Heteroclitin D can inhibit L-type calcium channels.
CFN80198	Senkyunolide O Senkyunolide O is a COX-2 selective inhibitor with the IC(50) value of 5 microM.
CFN80032	Neoruscogenin Neoruscogenin represents a universal pharmacological tool for RORα research due to its specific selectivity profile versus other nuclear receptors.
CFN80151	6''-O-xylosyl-glycitin Reference standards.
CFN80399	Physcion 8-O-beta-D-monoglucoside Physcion 8-O-beta-D-monoglucoside has anti-inflammatory activity, it can inhibit TNF-α-induced cytotoxicity and apoptosis in L929 cells via TNF-R1.

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