Natural Products
| Catalog No. | Information |
| CFN95055 | Lonicerin Lonicerin has antioxidant, anti-arthritic and antifungal activities, it can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection. |
| CFN95056 | Poricoic acid G Poricoic acid G shows inhibition of tumor-promoting effects and cytotoxic activity. |
| CFN95057 | 3''-O-Galloylmyricitrin Reference standards. |
| CFN95058 | Methyl lucidenate G Reference standards. |
| CFN95059 | Lucidumol A Lucidumol A has relatively good effect against aldose reductase with IC50 of 19.1uM. Lucidumol A has cytotoxic activity, it reduced cell growth in three human carcinoma cells (Caco-2, HepG2, and HeLa cells) dose dependently with LC50s from 20.87 to 84.36 uM. |
| CFN95060 | Angelol M Angelol M shows activity in inhibiting prostate specific antigen (PSA) secreted from androgen dependent prostate cancer cell line, LNCaP cells. |
| CFN95061 | Shancigusin I Shancigusin I is a natural from Cremastra appendiculata. |
| CFN95062 | 3-Methoxyshancigusin I Reference standards. |
| CFN91037 | Lirinidine (+)-Lirinidine has antioxidative activity, and it can significantly inhibit the proliferation of melanoma cells; it also shows potent inhibition of melanogenesis. Lirinidine exhibits significant inhibition of collagen, arachidonic acid and platelet activating factor-induced platelet aggregation. |
| CFN91038 | Epoxymicheliolide Epoxymicheliolide, a novelguaiane-type sesquiterpene lactone, inhibits NF‑κB/COX‑2 signaling pathways by targeting leucine 281 and leucine 25 in IKKβ in renal cell carcinoma, it may be a novel anticancer agent in the treatment of renal cell carcinoma. |
| CFN94150 | Eriodictyol chalcone Eriodictyol chalcone has anti-plasmodial effects on P. falciparum growth. |
| CFN95063 | Glicoricone Glicoricone acts as a partial estrogen antagonist. Glicoricone inhibited the monoamine oxidase with the IC50 values of 6.0 x 10(-5)-1.4 x 10(-4) M. |
| CFN95064 | Clemastanin B Clemastanin B has antioxidant and anti-inflammatory activities, it exerts its anti-influenza activity by inhibiting the virus multiplication, prophylaxsis and blocking the virus attachment. |
| CFN95065 | Glyasperin C Glyasperin C acts as a partial estrogen antagonist, it shows tyrosinase inhibitory activity (IC (50) = 0.13 +/- 0.01 microg/mL), it could be a promising candidate in the design of skin-whitening agents. Glyasperin C shows potent anti-vancomycin-resistant Enterococci effects (MIC 1.9 × 10-5-4.5 × 10-5 M for E. faecium and E. faecalis). |
| CFN95066 | Gancaonin N Reference standards. |
| CFN95067 | Lappaol A Lappaol A has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. Lappaol A also has potential chemosensitizing activity, it may be candidates for developing novel adjuvant anticancer agents. |
| CFN95068 | Lappaol C Lappaol C has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. Lappaol C also has potential chemosensitizing activity, it may be candidates for developing novel adjuvant anticancer agents. |
| CFN95069 | Lappaol F 1. Lappaol F has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. 2. Lappaol F has potential chemosensitizing activity, it may be candidates for developing novel adjuvant anticancer agents. 3. Lappaol F exhibits antitumor activity in vitro and in vivo and has strong potential to be developed as an anticancer therapeutic. 4. Lappaol F strongly inhibited NO production in the LPS-stimulated RAW264.7 cells with the IC(50) value of 9.5 microM. |
| CFN95070 | 7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin 7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin shows activity in inhibiting prostate specific antigen (PSA) secreted from androgen dependent prostate cancer cell line, LNCaP cells. |
| CFN95071 | Suspenoidside B Suspenoidside B possesses strong hepatoprotective activities against the damage in HepG2 cell. |
| CFN93005 | 4''-methyloxy-Daidzin Reference standards. |
| CFN93006 | 4''-methyloxy-Genistin Reference standards. |
| CFN93008 | Protodeltonin Protodeltonin may have anti-thrombotic activity by both improving the anticoagulation activity and inhibiting platelet aggregation action. Protodeltonin can inhibit the proliferation of a panel of established human and murine cancer cell lines in vitro. |
| CFN93009 | Isorosmanol Isorosmanol possesses antioxidant, neuroprotective and neurotrophic effects, it might be useful in ageing disorders such as the declining of cognitive functions and hyperpigmentation. |
| CFN93011 | 17-Hydroxyisolathyrol Reference standards. |
| CFN93012 | Angelicide Reference standards. |
| CFN93013 | Rubitecan Rubitecan is a novel oral inhibitor of topoisomerase I in the camptothecin class. It shows antitumour activity in patients with refractory pancreatic cancer who have failed prior treatments. |
| CFN93014 | Angelicolide Reference standards. |
| CFN93015 | Ingenol-5,20-acetonide-3-O-angelate Reference standards. |
| CFN93016 | Isolindleyin Reference standards. |
| CFN93017 | Rhodiosin Rhodiosin exhibits potent, dose-dependent inhibitory effects on acetylcholinesterase (AChE), it also can inhibit cytochrome P450 2D6 non-competitively with the IC50 value of 0.761 microM. Rhodiosin has hepatoprotective effects, it shows a protective effect on D-galactosamine-induced cytotoxicity in primary cultured mouse hepatocytes. Rhodiosin shows noncompetitive inhibition against Flavobacterium prolyl endopeptidase, with an IC50 of 41 microM, the enzyme that plays a role in the metabolism of proline-containing neuropeptidase which is recognized to be involved in learning and memory. Rhodiosin exhibits antioxidant activity, it could used as the treatment of lifestyle-related diseases such as hyperlipidemia and exogeneous obesity and as health foods. |
| CFN93018 | Aristolindiquinone Reference standards. |
| CFN93019 | Aaptamine Aaptamine functions as a proteasome inhibitor, it activates p21 promoter in a p53-independent manner. Aaptamine is a competitive antagonist of alpha-adrenoceptors in vascular smooth muscles. Aaptamine has potent cytotoxicity that may be explained by its ability to intercalate DNA, it exerts an antiproliferative effect against NT2-R, a cisplatin-resistant subline of the human embryonal carcinoma cell line NT2. Aaptamine shows anti-photoaging effect in UVB-irradiated human dermal fibroblasts and epidermal keratinocytes. Aaptamine also has anti-antiviral activity. |
| CFN93022 | 5-Methyl-7-methoxyisoflavone 5-Methyl-7-methoxyisoflavone is used by bodybuilders for its ergogenic properties. |
| CFN93023 | 20-O-Acetylingenol-3-angelate Reference standards. |
| CFN93024 | Rosmanol Rosmanol has antioxidant activity, it can activate the antioxidant response element, it also has biphasic modulation of GABAA receptors, demonstrates CNS activity in mouse models of antinociception, antidepressant and anxiolysis. Rosmanol exhibits significant cytotoxicity towards the neuroblastoma cells, it potently induces apoptosis through both the mitochondrial apoptotic pathway and death receptor pathway in human colon adenocarcinoma COLO 205 cells.Rosmanol has anti-inflammatory activity, it potently inhibits lipopolysaccharide-induced iNOS and COX-2 expression through downregulating MAPK, NF-kappaB, STAT3 and C/EBP signaling pathways. |
| CFN93025 | Zeylenol (-)-Zeylenol shows antifeedant activity. Zeylenol shows inhibitory activity toward the root growth of Lactuca sativa. Zeylenol probably possesses anti-inflammatory activity by inhibiting the synthesis or release of various inflammatory mediators and might be used to induce human breast cancer MDA-MB231 cell apoptosis. |
| CFN93026 | Conicasterol Conicasterol displays marked cytotoxic activity against human breast adenocarcinoma cell line (MCF-7) with the IC50 value of 6.23 ug/mL. |
| CFN93027 | Dehydronuciferine Dehydronuciferine shows inhibitory of acetylcholinesterase with the IC50 of 25 ug/mL. |
| CFN93028 | Beta-Hydroxyisovalerylshikonin Beta-Hydroxyisovalerylshikonin is an ATP non-competitive inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor cell lines. Beta-Hydroxyisovalerylshikonin has anti-adipogenic, antiinflammatory and antitumor effects, it activated AMPK, which was followed by the downregulation of mature SREBP‑1c and fat-forming enzymes, leading to the inhibition of adipogenesis. Beta-Hydroxyisovalerylshikonin can significantly decrease viability of HCT116 cells (IC50 values of 30.9 ug/mL). |
| CFN93029 | Foresaconitine Reference standards. |
| CFN93030 | Ungeremine Ungeremine is a potential biofungicide against Penicillium roqueforti and Aspergillus niger, it has strong antibacterial activity against Flavobacterium columnare. Ungeremine also has antiprotozoal activity, it shows good activity in in vitro assays against Trypanosoma brucei rhodesiense, T. cruzi. Ungeremine effectively targets mammalian as well as bacterial type I and type II topoisomerases. Ungeremine also shows strong acetylcholinesterase inhibitory activity(IC(50) value of 0.35 microM). |
| CFN93031 | Laetanine Reference standards. |
| CFN93032 | Obtusin Reference standards. |
| CFN93033 | Kahweol Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaB degradation and inhibiting IkappaB kinase activity. Kahweol also has hepatoprotective and antioxidant effects on carbon tetrachloride-induced liver damage in mice. |
| CFN93034 | Lotusine Lotusine has antihypertension and antibacterial activities. |
| CFN93035 | Gigantol Gigantol is a novel inhibitor of the Wnt/β-catenin pathway, it inhibits Wnt/β-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic β-catenin in breast cancer cells, it induces growth inhibition and apoptosis of HepG2 cells via the PI3K/Akt/NF-κB signaling pathway. Gigantol may be developed as a promising neuroprotective agent for successful MSC transplantation in ischemic diseases, it shows protective effect against hydrogen peroxide-induced apoptosis in rat bone marrow mesenchymal stem cells through the PI3K/Akt pathway. Gigantol inhibits aldose reductase gene to exert its anti-cataract activity. Gigantol also shows α-glucosidase inhibitory activity. |
| CFN93036 | Isorhamnetin 3-O-galactoside Isorhamnetin 3-O-galactoside shows antioxidant, anti-inflammatory, neuroprotective,and barrier protective activities, it could be used as a candidate therapeutic for treatment of severe vascular inflammatory diseases.It has potential anticoagulant activity, it possesses antithrombotic and profibrinolytic activity and offers bases for development of a novel anticoagulant. Isorhamnetin 3-O-galactoside is also a 5-lipoxygenase inhibitor, it may have therapeutic potential in skin inflammatory disorders in traditional medicine. |
| CFN93037 | Alloimperatorin Alloimperatorin exhibits in vitro antitumor activity in HL-60 acute myeloid leukemia cancer cells via inducing apoptosis, cell cycle disruption and inhibition of cell migration. It photosensitizes efficiently the hemolysis of erythrocytes. |
| CFN93038 | Pseudoprotogracillin Reference standards. |
