Natural Products
| Catalog No. | Information |
| CFN91895 | Withaferin A Withaferin A(WFA) has anti-inflammatory, anti-oxidant, immune modulatory, cardioactive, antithrombotic and central nervous system effects, it could act as an anti-fibrotic compound against fibroproliferative diseases, including, but not limited to, cardiac interstitial fibrosis. WFA is a proteasomal inhibitor promotes healing after injury and exerts anabolic effect on osteoporotic bone. WFA is a potent breast cancer anti-metastatic agent and the anti-metastatic activity of WFA is, at least in part, mediated through its effects on vimentin and vimentin ser56 phosphorylation; it induces p53-dependent apoptosis by repression of HPV oncogenes and upregulation of tumor suppressor proteins in human cervical cancer cells, it can be exploited as a potent therapeutic agent for the treatment and prevention of cervical cancer without deleterious effects. |
| CFN91894 | Plantagoside Plantagoside is a potent inhibitor of the Maillard reaction, it also can inhibit the formation of advanced glycation end products in proteins in physiological conditions and inhibit protein cross-linking glycation. It is also a specific non-competitive inhibitor for jack bean alpha-mannosidase (IC50 at 5 microM). Plantagoside suppresses antibody response to sheep red blood cells and concanavalin A induced lymphocyte proliferation which was measured by [3H]thymidine incorporation. Plantagoside has potential therapeutic applications in the prevention of diabetic complications. |
| CFN91893 | Ardisicrenoside B Reference standards. |
| CFN91892 | Methyloleoside Reference standards. |
| CFN91891 | Epimedokoreanin C Reference standards. |
| CFN91890 | Trimethylapigenin Trimethyapigenin has anti-inflammatory activity, it can moderately inhibit production of TNF-α. ,iNOS mRNA and iNOS protein in a dose-dependent manner. It may be a potential candidate for anti-atrial fibrillation, it can significantly inhibit the atrial potassium currents hKv1.5/I(Kur) and I(KACh). |
| CFN91889 | Tetramethylkaempferol Tetramethylkaempferol is a PPARγ agonist, it can improve insulin sensitivity by increasing the levels of adiponectin, an important adipocytokine associated with insulin sensitivity in adipose tissue. Tetramethylkaempferol can concentration-dependently enhance the accumulation of triglyceride, a marker of adipogenesis. |
| CFN91888 | Citrusinol Citrusinol exhibits cytotoxic activities against the HepG2 cell. |
| CFN91887 | Maohuoside B Reference standards. |
| CFN91886 | Negletein Negletein has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β, it also shows a comparable redox-active potential, and it (50 μM, 4 h) can activate Nrf2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells, it has anti- Alzheimer's disease activity, it inhibits the iron-dependent formation of ROS and also blocks the iron-induced oligomerization of amyloid beta 42 in vitro. Negletein has anti-hypoxia activity, it can significantly prolong the survival time of hypoxic mice.Negletein also shows significant antimicrobial activity. |
| CFN91885 | Vitexin-2''-O-p-trans-coumarate Vitexin-2''-O-p-trans-coumarate can strongly promote 2BS cell proliferation induced by H(2)O(2). |
| CFN91884 | Orientin-2''-O-p-trans-coumarate Orientin-2''-O-p-trans-coumarate can strongly promote 2BS cell proliferation induced by H(2)O(2). |
| CFN91883 | Isomucronulatol 7-O-beta-glucoside Reference standards. |
| CFN91882 | Odoratin-7-O-beta-D-glucopyranoside Reference standards. |
| CFN91881 | Phytolaccagenic acid Reference standards. |
| CFN91880 | Alloalantolactone Alloalantolactone shows activity against M. tuberculosis (32 micrograms/ml). |
| CFN91879 | Pseudolarolide Q2 Pseudolarolide Q exhibits strong antimicrobial activity against Gram-positive Staphylococcus aureus and Candida albicans at the MICs of 6.08 and 24.32 uM. |
| CFN91878 | Pseudolarolide B Reference standards. |
| CFN91877 | Pseudolarolide F Reference standards. |
| CFN91876 | Bisabolangelone Bisabolangelone has anti-tumor, anti-inflammatory, anti-microbial, and antioxidant activities, it inhibits dendritic cell functions by blocking MAPK and NF-κB signaling. Bisabolangelone has antimelanogenic activity, the cAMP-binding site of PKA as a putative target ameliorating melanocyte-specific hyperpigmented disorder. Bisabolangelone has anti-ulcer activity, it is possible that bisabolangelone inhibited the activity of the H(+)/K(+)-ATPase, then reducing the secretion of H(+). It also inhibits the activity of 5alpha-reductase type I in LNCaP cells (IC50 = 11.6 microg/ml). |
| CFN91875 | Aristololactam II Reference standards. |
| CFN91874 | Aristoliukine B Reference standards. |
| CFN91873 | Colupulone Colupulone is an inducer of hepatic cytochrome P-4503A .Colupulone can increase cytochrome P450IIB and P450IIIA steady-state mRNA levels. Colupulone also has antibacterial effects. |
| CFN91872 | Delta-9-Tetrahydrocannabinolic acid Delta-9-Tetrahydrocannabinolic acid can protect dopaminergic neurons against MPP(+) induced cell death. |
| CFN91001 | 5,7-Dimethoxyluteolin 5,7-Dimethoxyluteolin is a natural product from Hovenia acerba. |
| CFN91002 | Oxysanguinarine Oxysanguinarine possesses antiplatelet aggregation activity, it has potential inhibitory properties against dengue virus. |
| CFN91003 | Isocucurbitacin B Isocucurbitacin B has significantly activities against HeLa and HT-29 human cancer cells with IC50 values ranging from 0.93 to 9.73uM. |
| CFN89530 | Axillarin Axillarin has antioxidant activity, it shows xanthine oxidase inhibitory activity ( IC(50) :36.0 uM). Axillarin can strongly protect primary cultured neurons against glutamate-induced oxidative stress. |
| CFN89531 | Obtusafuran methyl ether Reference standards. |
| CFN89532 | 5-O-Methyldalbergiphenol Reference standards. |
| CFN89533 | Eriodictyol 7,3'-dimethyl ether Reference standards. |
| CFN89534 | Deltatsine Reference standards. |
| CFN89535 | 3-Methoxyoxohernandaline Reference standards. |
| CFN89536 | Alnusone Reference standards. |
| CFN89537 | 14-Dehydrobrowniine Reference standards. |
| CFN89538 | Ageratochromene dimer Reference standards. |
| CFN89539 | Acetylatractylodinol Reference standards. |
| CFN89540 | 3,5-Dimethoxy-3'-hydroxybibenzyl Reference standards. |
| CFN89541 | Carpinontriol B Carpinontriol B has antimicrobial activity, it at 40 ug/disk caused the formation of zones of inhibition. It also has anti-inflammatory activity, it shows considerable inhibition on the production of nitric oxide and reduces the production of interleukin-6 in dose-dependent manner in RAW 264.7 cells. |
| CFN89542 | Aromadendrin 7-O-rhamnoside Reference standards. |
| CFN89543 | 12-Hydroxy-2,3-dihydroeuparin Reference standards. |
| CFN89544 | Giffonin R Reference standards. |
| CFN89545 | Polypodine B Polypodine B shows growth-promoting effects on in vitro development of the larval endoparasitoid, Venturia canescens (Hymenoptera: Ichneumonidae). |
| CFN89546 | Nardosinonediol Nardosinonediol shows cytotoxic activity against P-388 cells. |
| CFN89547 | 14-Dehydrodelcosine Reference standards. |
| CFN89548 | 1,2,3,10-Tetramethoxy-9-(2-hydroxy-4,5-dimethoxybenzyloxy)oxoaporphine Reference standards. |
| CFN89549 | 1,5,6-Trihydroxy-3-methoxyxanthone 1,5,6-Trihydroxy-3-methoxyxanthone exhibits scavenging activity at 10 uM, it can reduce the viability of HL-60 cells significantly with IC50 values of 28.9 uM. |
| CFN89550 | Delgrandine Reference standards. |
| CFN91004 | Salvianolic acid Y Salvianolic acid Y is a new protector of PC12 cells against hydrogen peroxide-induced injury from Salvia officinalis. |
| CFN91005 | Monomethyl lithospermate Reference standards. |
