Natural Products
| Catalog No. | Information |
| CFN92836 | Peroxydehydrotumulosic acid 5alpha,8alpha-Peroxydehydrotumulosic acid exhibits inhibitory effects against the Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) in Raji cells. |
| CFN92826 | Cis-N-Feruloyltyramine Cis-N-Feruloyltyramine shows cytotoxicity against the P-388 cancer cell line. N-cis-Feruloyltyramine and N-trans-Feruloyltyramine are the inhibitors of in vitro prostaglandin (PG) synthesis. |
| CFN97865 | Eriodictyol-7-O-glucoside Eriodictyol-7-O-glucoside and epicatechin appears to be responsible for the antioxidant activity of pistachio skin.Eriodictyol-7-O-glucoside has protective effect on cisplatin-induced toxicity was investigated in a human renal mesangial cell line, HRMC; it also can activate Nrf2/ARE signaling, directly associated with its neuroprotection against oxidative stress-induced ischemic; suggests that targeting the Nrf2/ARE pathway may be a promising approach for therapeutic intervention in stroke. |
| CFN92818 | Ginsenoside Rk2 Ginsenoside Rk1 has anti-tumor, and anti-platelet aggregation activities. Ginsenoside Rk1 can strongly inhibit permeability induced by VEGF, advance glycation end-product, thrombin, or histamine in human retinal endothelial cells, it reduces the vessel leakiness of retina in a diabetic mouse model; this anti-permeability activity of Rk1 is correlated with enhanced stability and positioning of tight junction proteins at the boundary between cells; Rk1 induces phosphorylation of myosin light chain and cortactin, which are critical regulators for the formation of the cortical actin ring structure and endothelial barrier. |
| CFN92810 | Dihydrosanguinarine Dihydrosanguinarine has antifungal and anticancer activity.Dihydrosanguinarine at concentrations from 5 microM induced primarily necrosis, whereas apoptosis occurred at 10 microM and above. Dihydrosanguinarine has potential application in the therapy of serious infection caused by I. multifiliis. |
| CFN92809 | Isosakuranin Isosakuranin is a product from Paliurus ramosissimus. |
| CFN92806 | 3,4'-Di-O-methylellagic acid Reference standards. |
| CFN92800 | Qianhucoumarin G Qianhucoumarin G is a natural product from Peucedanum praeruptorum. |
| CFN92799 | cis-Khellactone cis-Khellactone is a natural product from Angelica sinensis. |
| CFN92798 | Panaxydiol Panaxydiol can inhibit rat liver cholesterol acyltransferase (ACAT) with IC50 values of 45 microM. |
| CFN92792 | Curculigoside C Standard reference |
| CFN92776 | Galangin 3-methyl ether Galangin-3-methylether has antibacterial activity, it has inhibitory effects on Pseudomonas aeruginosa. 3-Methylethergalangin has hypolipidemic activity, the action is due to the inhibition of pancreatic lipase. |
| CFN90557 | Oxypeucedanin hydrate Oxypeucedanin hydrate is an antimutagenic agent, it has antioxidant activity, and exhibits carbohydrate metabolizing enzymes inhibitory effect. |
| CFN92764 | Tilianin Tilianin has anti-inflammatory, antiatherogenic, antihypertensive and vasorelaxant activities, mediates relaxation and antihypertension mainly by an endothelium-dependent manner, probably due to NO release, and also through an endothelium-independent pathway by opening K+ channels. Tilianin inhibits the tumor necrotic factor-K (TNF-K)-induced expression of VCAM-1 by 74% and reduces TNF-K-induced activation of nuclear factor-UB in cultured human umbilical vein endothelial cells (HUVECs). |
| CFN92757 | Ajugamarin L2 (Ajugacumbin B) Reference standards. |
| CFN92755 | Ajuganipponin A Reference standards. |
| CFN92752 | Ajugacumbin A Reference standards. |
| CFN92750 | Loliolid Loliolid is a germination inhibitor, and a repellent for ants (Atta cephalotes).It has cytostatic activity against carcnoma and leukaemia cells. |
| CFN92744 | Glycosmisic acid Glycosmisic acid is a natural product from Nauclea officinalis. |
| CFN92743 | 3-Epidehydrotumulosic acid 3-Epidehydrotumulosic acid has inhibitory activity against AAPH-induced lysis of red blood cells. |
| CFN92742 | Dehydropachymic acid Dehydropachymic acid shows antiinflammatory activity. |
| CFN92741 | 6alpha-Hydroxypolyporenic acid C 6alpha-Hydroxypolyporenic acid C is a natural product from Wolfiporia cocos (Schw.) Ryv. |
| CFN92740 | Dehydroeburicoic acid Dehydroeburicoic acid induces necrotic cell death that involves Ca(2+) overload, mitochondrial dysfunction, and calpain activation in human glioblastomas. Dehydroeburicoic acid and Eburicoic acid have antioxidant and anti-inflammatory activities by the decrease of inflammatory cytokines and an increase of antioxidant enzyme activity, can protect the liver from CCl4-induced hepatic damage. |
| CFN92739 | Polyporenic acid C Polyporenic acid C shows inhibitory activity against human collagenase. Polyporenic acid C induces apoptosis through the death receptor-mediated apoptotic pathway where the activation of caspase-8 leads to the direct cleavage of execution caspases without the involvement of the mitochondria. |
| CFN92738 | 3-Epidehydropachymic acid Reference standards. |
| CFN92719 | Gomisin F Standard reference |
| CFN92716 | Gomisin S Reference standards. |
| CFN92715 | Schisantherin C Schisantherin A, B, C, and D show good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis. |
| CFN92712 | Marmesin Marmesin has hepatoprotective potential; it also has cytotoxic with a 50% lethal dose of less than 0.5 micrograms/ml, is not as mutagenic or potentially carcinogenic as are AFB1, imperatorin, or MOP with BL activation. |
| CFN92709 | Qianhucoumarin A Standard reference |
| CFN92706 | 6-Methoxyluteolin 6-Methoxyluteolin has antioxidant activity, it is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain. |
| CFN92703 | 3-Hydroxybakuchiol 3-Hydroxybakuchiol exerts cytotoxic and anti-proliferative effects on the TA3/Ha mouse mammary adenocarcinoma cell line and induces a decrease in the mitochondrial transmembrane potential, the activation of caspase-3, the opening of the mitochondrial permeability transport pore (MPTP) and nuclear DNA fragmentation.3-Hydroxybakuchiol has antitumor activity resulting from interactions with the ETC, a system that is already deficient in cancer cells. |
| CFN92702 | 12-Hydroxyisobakuchiol Standard reference |
| CFN92693 | Coelonin Coelonin shows moderate cytotoxic activity against HepG2 cells. |
| CFN92685 | 1,7-Diphenyl-4-hepten-3-one 1,7-Diphenyl-4-hepten-3-one has feeding deterrent activities against Tribolium castaneum. |
| CFN92684 | (R)-5-Hydroxy-1,7-diphenyl-3-heptanone Reference standards. |
| CFN92674 | 2H-1-Benzopyran-5-ol Reference standards. |
| CFN92669 | Euchrestaflavanone A Euchrestaflavanone A is an inhibitor of MRP1-like efflux activity in human erythrocytes. It reveals potent cytotoxicities against one or more cell lines with IC 50 values in the range of 4.5–9.961μM. |
| CFN92656 | Kawain Kavain has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels. Kawain is advanced glycation endproduct inhibitors, can increase the mean life span of Caenorhabditis elegans exposed to high glucose. |
| CFN92652 | Zedoarondiol Zedoarondiol has anti-inflammatory activity, inhibits iNOS, COX-2, and pro-inflammatory cytokine expressions by suppressing the phosphorylations of IKK and MAPKs, and by subsequently inactivating the NF-kappaB pathway. It dose-dependently inhibits LPS-stimulated nitric oxide (NO), prostaglandin E(2) (PGE(2)), tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), and interleukin-1beta (IL-1beta) productions in RAW 264.7 macrophage and in mouse peritoneal macrophage cells. |
| CFN92648 | 13-Hydroxygermacrone 13-Hydroxygermacrone inhibits UVB-induced upregulation of the mRNA and protein expression levels of MMP-1, MMP-2, and MMP-3 in human keratinocytes (HaCaT). 13-Hydroxygermacrone shows a protective effect against D-GalN/tumor necrosis factor-alpha-induced liver injury in mice at a dose of 50 mg/kg p.o. |
| CFN92647 | Procurcumenol Procurcumenol is an inhibitor of Nitric Oxide. Procurcumenol and epicurcumenol have inhibitory effects on release of tumor necrosis factor-a (TNF-a). |
| CFN92643 | Ginsenoside Rg5 Ginsenoside Rg5 plays a novel role as an IGF-1R agonist, promoting therapeutic angiogenesis and improving hypertension without adverse effects in the vasculature, it can ameliorate lung inflammation possibly by inhibiting the binding of LPS to toll-like receptor (TLR)-4 on macrophages. Ginsenoside Rg5 blocks cell cycle of SK-HEP-1 cells at the Gl/S transition phase by down-regulating cyclin E-dependent kinase activity and that the down-regulation of cyclin E-dependent kinase activity is caused mainly by induced CDK2 inhibitor, p21Cip/WAF1 and decreased levels of cyclin E. |
| CFN92616 | Zederone Zederone has anti-bacterial activity,it inhibits gram-positive bacteria activity. Zederone induces hepatotoxicity implicated the induction of Cyps, which leads to the formation of biological reactive metabolites and that cause the oxidative stress and liver cell injuries. |
| CFN92614 | Curcumenol Curcumenol possesses a variety of health and medicinal values which includes neuroprotection, anti-inflammatory, anti-tumor and hepatoprotective activities. It inhibits NF-κB activation by suppressing the nuclear translocation of the NF-κB p65 subunit and blocking IκBα phosphorylation and degradation. |
| CFN92603 | Rubinaphthin A Rubinaphthin A is a natural product from Rubia cordifolia. |
| CFN92601 | Britannilactone Britannilactone significantly reduces melanin production in a dose-dependent manner with the IC50 value of 15.5 uM. |
| CFN92600 | 1beta-Hydroxyalantolactone 1beta-Hydroxyalantolactone has protective effect against AD-like skin inflammation, can as a potential therapeutic agent for AD. |
| CFN92599 | Ivangustin Ivangustin exhibits remarkable cytotoxicity against HEp2, SGC-7901 and HCT116 human cancer cell lines. |
| CFN92597 | Qianhucoumarin E Standard reference |
