Natural Products
| Catalog No. | Information |
| CFN92741 | 6alpha-Hydroxypolyporenic acid C 6alpha-Hydroxypolyporenic acid C is a natural product from Wolfiporia cocos (Schw.) Ryv. |
| CFN92740 | Dehydroeburicoic acid Dehydroeburicoic acid induces necrotic cell death that involves Ca(2+) overload, mitochondrial dysfunction, and calpain activation in human glioblastomas. Dehydroeburicoic acid and Eburicoic acid have antioxidant and anti-inflammatory activities by the decrease of inflammatory cytokines and an increase of antioxidant enzyme activity, can protect the liver from CCl4-induced hepatic damage. |
| CFN92739 | Polyporenic acid C Polyporenic acid C shows inhibitory activity against human collagenase. Polyporenic acid C induces apoptosis through the death receptor-mediated apoptotic pathway where the activation of caspase-8 leads to the direct cleavage of execution caspases without the involvement of the mitochondria. |
| CFN92738 | 3-Epidehydropachymic acid Reference standards. |
| CFN92719 | Gomisin F Standard reference |
| CFN92716 | Gomisin S Reference standards. |
| CFN92715 | Schisantherin C Schisantherin A, B, C, and D show good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis. |
| CFN92712 | Marmesin Marmesin has hepatoprotective potential; it also has cytotoxic with a 50% lethal dose of less than 0.5 micrograms/ml, is not as mutagenic or potentially carcinogenic as are AFB1, imperatorin, or MOP with BL activation. |
| CFN92709 | Qianhucoumarin A Standard reference |
| CFN92706 | 6-Methoxyluteolin 6-Methoxyluteolin has antioxidant activity, it is a potent inhibitor of histamine release and calcium influx via down-regulation of the FcεRI α chain. |
| CFN92703 | 3-Hydroxybakuchiol 3-Hydroxybakuchiol exerts cytotoxic and anti-proliferative effects on the TA3/Ha mouse mammary adenocarcinoma cell line and induces a decrease in the mitochondrial transmembrane potential, the activation of caspase-3, the opening of the mitochondrial permeability transport pore (MPTP) and nuclear DNA fragmentation.3-Hydroxybakuchiol has antitumor activity resulting from interactions with the ETC, a system that is already deficient in cancer cells. |
| CFN92702 | 12-Hydroxyisobakuchiol Standard reference |
| CFN92693 | Coelonin Coelonin shows moderate cytotoxic activity against HepG2 cells. |
| CFN92685 | 1,7-Diphenyl-4-hepten-3-one 1,7-Diphenyl-4-hepten-3-one has feeding deterrent activities against Tribolium castaneum. |
| CFN92684 | (R)-5-Hydroxy-1,7-diphenyl-3-heptanone Reference standards. |
| CFN92674 | 2H-1-Benzopyran-5-ol Reference standards. |
| CFN92656 | Kawain Kavain has anticonvulsive properties, attenuating vascular smooth muscle contraction through interactions with voltage-dependent Na+ and Ca2+ channels. Kawain is advanced glycation endproduct inhibitors, can increase the mean life span of Caenorhabditis elegans exposed to high glucose. |
| CFN92652 | Zedoarondiol Zedoarondiol has anti-inflammatory activity, inhibits iNOS, COX-2, and pro-inflammatory cytokine expressions by suppressing the phosphorylations of IKK and MAPKs, and by subsequently inactivating the NF-kappaB pathway. It dose-dependently inhibits LPS-stimulated nitric oxide (NO), prostaglandin E(2) (PGE(2)), tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), and interleukin-1beta (IL-1beta) productions in RAW 264.7 macrophage and in mouse peritoneal macrophage cells. |
| CFN92648 | 13-Hydroxygermacrone 13-Hydroxygermacrone inhibits UVB-induced upregulation of the mRNA and protein expression levels of MMP-1, MMP-2, and MMP-3 in human keratinocytes (HaCaT). 13-Hydroxygermacrone shows a protective effect against D-GalN/tumor necrosis factor-alpha-induced liver injury in mice at a dose of 50 mg/kg p.o. |
| CFN92647 | Procurcumenol Procurcumenol is an inhibitor of Nitric Oxide. Procurcumenol and epicurcumenol have inhibitory effects on release of tumor necrosis factor-a (TNF-a). |
| CFN92643 | Ginsenoside Rg5 Ginsenoside Rg5 plays a novel role as an IGF-1R agonist, promoting therapeutic angiogenesis and improving hypertension without adverse effects in the vasculature, it can ameliorate lung inflammation possibly by inhibiting the binding of LPS to toll-like receptor (TLR)-4 on macrophages. Ginsenoside Rg5 blocks cell cycle of SK-HEP-1 cells at the Gl/S transition phase by down-regulating cyclin E-dependent kinase activity and that the down-regulation of cyclin E-dependent kinase activity is caused mainly by induced CDK2 inhibitor, p21Cip/WAF1 and decreased levels of cyclin E. |
| CFN92616 | Zederone Zederone has anti-bacterial activity,it inhibits gram-positive bacteria activity. Zederone induces hepatotoxicity implicated the induction of Cyps, which leads to the formation of biological reactive metabolites and that cause the oxidative stress and liver cell injuries. |
| CFN92614 | Curcumenol Curcumenol possesses a variety of health and medicinal values which includes neuroprotection, anti-inflammatory, anti-tumor and hepatoprotective activities. It inhibits NF-κB activation by suppressing the nuclear translocation of the NF-κB p65 subunit and blocking IκBα phosphorylation and degradation. |
| CFN92603 | Rubinaphthin A Rubinaphthin A is a natural product from Rubia cordifolia. |
| CFN92601 | Britannilactone Britannilactone significantly reduces melanin production in a dose-dependent manner with the IC50 value of 15.5 uM. |
| CFN92600 | 1beta-Hydroxyalantolactone 1beta-Hydroxyalantolactone has protective effect against AD-like skin inflammation, can as a potential therapeutic agent for AD. |
| CFN92599 | Ivangustin Ivangustin exhibits remarkable cytotoxicity against HEp2, SGC-7901 and HCT116 human cancer cell lines. |
| CFN92597 | Qianhucoumarin E Standard reference |
| CFN92594 | Ginsenoside Rh4 Ginsenoside Rh4 is a rare saponin obtained from Panax notoginseng. Ginsenoside Rh4 activates Bax, caspase 3, caspase 8, and caspase 9. Ginsenoside Rh4 also induces autophagy. Ginsenoside Rh4 could be safely used as adjuvant with low or non-haemolytic effect; it has cytotoxic activity and its aglycone against cancer cell lines. |
| CFN92593 | Ginsenoside Rk3 Ginsenoside Rk3 is often used as a major ingredient of the compound preparation for ischemic heart diseases, it could have a role in treating inflammatory diseases. Ginsenoside Rk3 significantly inhibits TNF-α-induced NF-κB transcriptional activity, with an IC50 of 14.24±1.30 μM in HepG2 cells. |
| CFN92574 | 3-Oxopomolic acid Reference standards. |
| CFN00447 | 1,2,3,6-Tetragalloylglucose 1,2,3,6-Tetragalloylglucose has antioxidative activity, it also shows the most potent anticomplement activity (IC(50), 34 microM). |
| CFN90539 | Homoarbutin Reference standards. |
| CFN90536 | Dihydrokavain Dihydrokavain may play an important role in regulation of GABAergic neurotransmission, it non-competitively inhibits the specific binding of [3H]-batrachotoxinin-A 20-alpha-benzoate to receptor site 2 of voltage-gated Na+ channels. Dihydrokavain may treat sleep disturbances, as well as stress and anxiety. |
| CFN90531 | 3-O-Acetyl-11-keto-beta-boswellic acid 3-O-Acetyl-11-keto-beta-boswellic acid inhibits 5-lipoxygenase product formation with an IC(50) of 1.5 m muM. |
| CFN90526 | Cistanoside A Cistanoside A possesses protective activities on CCl4 induced hepatotoxicity in mice, which is involved with increasing free radicals clearing activities, alleviating lipid-overoxidation damage, and improving respiratory chain function in mitochondria. |
| CFN90521 | Demethylwedelolactone Demethylwedelolactone has trypsin inhibitory effect, it exerts anti-invasive growth effect on breast cancer cells. |
| CFN90518 | Deoxyandrographolide Deoxyandrographolide promotes glucose uptake through glucose transporter-4 translocation to plasma membrane in L6 myotubes and exerts antihyperglycemic effect in vivo. |
| CFN90517 | 7-Hydroxyaristolochic acid A 7-Hydroxyaristolochic acid A is a natural product from Aristolochia debilis Sieb. et Zucc. |
| CFN90516 | Aristolochic acid C Aristolochic acid C could as the larval feeding stimulants. |
| CFN90513 | Periplocin Periplocin has anti-cancer, and potent immunoregulatory effects, it induces apoptosis and inhibits growth of cancer cells by the beta-catenin/Tcf signaling pathway. Periplocin is used for treatment of rheumatoid arthritis, reinforcement of bones and tendons, palpitations or shortness of breath and lower extremity edema in traditional medicine. |
| CFN90511 | Phillygenin Phillyrin, (+)-Phillygenin, and (-)-phillygenin exert the strongest inhibitory activities on NO production with IC(50) values. |
| CFN92573 | 3-O-Caffeoylquinic acid methyl ester 3-O-Caffeoylquinic acid methyl ester is a natural product from Morus alba L. |
| CFN90510 | Columbianetin acetate Columbianetin may be helpful in regulating mast cell-mediated allergic inflammatory responses, the absorption of columbianetin acetate is a passive diffusion process without pH-dependent. |
| CFN90508 | Oxoglaucine Oxoglaucine exerts immunomodulatory effect in vivo in a dose-dependent and protocol-dependent manner, it also exhibits significant antiplatelet aggregation activity against rabbit platelets induced by thrombin, arachidonic acid, collagen or platelet activating factor. Oxoglaucine and pachypodol are anti-picornavirus compounds, phosphatidylinositol 4-kinase III beta (PI4KB) as the direct target of them. |
| CFN92559 | (+)-Pteryxin (+)-Pteryxin has muscle-relaxant props, it also shows hepatoprotective and nitric oxide prodn. inhibitory activity. |
| CFN92551 | 2''-O-Rhamnosylicariside II 2″-O-Rhamnosylicariside II shows potent antioxidant activity, with IC50 values of 11.5 ug/mL and 90.5 uM. It shows potent inhibitory activities on osteoclast-like cell formation at a concentration of 2 uM without toxic effects. |
| CFN92547 | 16-Oxoalisol A Reference standards. |
| CFN92545 | Alisol C Alisol C can improve glucose uptake in Hep G2 cells, it may be one of the therapeutic material basis in hypoglycemic activities in A. orientalis. Alisol C,16,23-oxido-alisol B and alisol O in Zexie may cause nephrotoxicity. |
| CFN92543 | 25-O-Methylalisol A Reference standards. |
