Natural Products
| Catalog No. | Information |
| CFN98179 | p-Hydroxy-cinnamic acid p-Hydroxy-cinnamic acid may have in vitro antimalarial activity. p-Hydroxycinnamic acid and β-cryptoxanthin have anti-osteoporotic properties in vivo, they can antagonize NF-κB activation in MC3T3 preosteoblastic cells。 |
| CFN98180 | Ethyl 4-methoxycinnamate Ethyl p-methoxycinnamate(Ethyl 4-methoxycinnamate) has antifungal activity, it can inhibit the growth of Trichophyton rubrum, Aspergillus niger, Saccharomyces cerevisiae and Epidermophyton floccosum at a concentration less than 10 mug/ml. Ethyl-p-methoxycinnamate has anti-inflammatory, it can dose-dependently inhibit carrageenan-induced edema with an MIC of 100 mg/kg, and non-selectively inhibit the activities of cyclooxygenases 1 and 2, with IC50 values of 1.12 uM and 0.83 uM respectively; it has chemopreventive activity against fibrosarcoma through inhibition of COX-2, and can block bFGF-induced vessel formation on Matrigel plug assay in vivo. Ethyl p-methoxycinnamate could be developed as a skin whitening agent to treat hyperpigmentary disorders. |
| CFN98373 | Amygdalin Amygdalin has antifibrotic, antitumor, anti-inflammatory and analgesic effects, amygdalin joint HSYA could inhibit the degeneration of the endplate chondrocytes derived from intervertebral discs of rats induced by IL-1beta and better than the single use of Amygdalin or HSYA. Amygdalin induces apoptotic cell death in human DU145 and LNCaP prostate cancer cells by caspase-3 activation through down-regulation of Bcl-2 and up-regulation of Bax. |
| CFN98374 | 7-Hydroxy-6-methoxy-3-prenylcoumarin Reference standards. |
| CFN98375 | Robinin Robinin has cardioprotective effect on doxorubicin-induced cardiac toxicity by modulating TGF-β1 signaling pathway in Sprague Dawley rats. Robinin has protective effect against the ox-LDL induced inflammation stress in hPBMCs by inhibiting TLR4-NF-κB signaling pathway. |
| CFN98376 | Seneganolide Seneganolide has insect antifeeding activity. Seneganolide A has antifungal activity. |
| CFN98377 | Effusanin A Effusanin A has antibacterial activity. It exhibits DNA-damaging activity in assay which employed DNA-repair deficient (RAD 52Y) and repair proficient (RAD +) yeast strains. Effusanin A shows inhibitory effects on DU145 cells with IC50 value of 3.16 microM, and LoVo cells with IC50 value of 3.02 microM. |
| CFN98378 | 1-Hydroxybaccatin I 1beta-Hydroxybaccatin I possesses significant antinociceptive activity against p- benzoquinone-induced abdominal contractions. |
| CFN98379 | 3,4,5-Trimethoxycinnamyl alcohol 3,4,5-Trimethoxycinnamyl alcohol shows significant antimicrobial and cytotoxic activities. |
| CFN98380 | Pandamarilactonine A Pandamarilactonine A has antimicrobial activity, it is active with an MIC of 15.6 ug/mL and MBC of 31.25 ug/mL against Pseudomonas aeruginosa. |
| CFN98381 | Pandamarilactonine B Standard reference |
| CFN98382 | Picrasin B acetate Reference standards. |
| CFN98383 | Centrolobol (-)-Centrolobol has antifibrotic activity, it can significantly inhibit the proliferation of HSC-T6 cells in a dose-dependent manner. Centrolobol exhibits strong cytotoxic activity against KB cell line. |
| CFN98384 | Corydalmine Corydalmine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains.1-Corydalmine significantly inhibits spore germination of all the fungi at 100 to 1500 ppm. l-Corydalmine also exhibits potent analgesic activity in preclinical models, it is under development as an oral analgesic agent. |
| CFN98385 | Harmaline Harmaline is a central nervous system stimulant and an acetylcholinesterase (AChR) inhibitor; also inhibits histamine N-methyltransferase. Harmaline has antileishmanial, bioinsecticidal, and vasorelaxant effects. It has antagonist effects on alpha1-adrenorecepteors in non-competitive manner, it also exerts an antioxidant activity by scavenging the free radical generated by DPPH.Harmaline may prevent dopamine-induced mitochondrial damage and PC12 cell death through a scavenging action on reactive oxygen species and inhibition of monoamine oxidase and thiol oxidation. |
| CFN98386 | Xerophilusin G Reference standards. |
| CFN98387 | Mearnsitrin Reference standards. |
| CFN98388 | 5'-Demethylaquillochin 5'-Demethylaquillochin and its isomer from the dichloromethane extract of E. cavaleriei have potential as chemopreventive agents through induction of detoxification enzymes. 5'-Demethylaquillochin exhibits the most potential chemopreventive ability. |
| CFN98389 | beta-Anhydrouzarigenin Reference standards. |
| CFN98390 | 4-Oxododecanedioic acid 4-Oxododecanedioic acid is a natural product from Coniogramme japonica. |
| CFN98391 | Magnolin Magnolin has anti-inflammatory, anti-histaminic, and antioxidative effects, it might be a naturally occurring chemoprevention and therapeutic agent capable of inhibiting cell proliferation and transformation by targeting ERK1 and ERK2. Magnolin can ameliorate the renal tubular necrosis, apoptosis, and the deterioration of renal function, it reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo and in vitro. |
| CFN98392 | Echinophyllin C Reference standards. |
| CFN98393 | 5,7,3'-Trihydroxy-6,4',5'-trimethoxyflavanone Reference standards. |
| CFN98394 | Sideroxylin Sideroxylin can synergistically enhance the antimicrobial activity of the alkaloid berberine (also a constituent of H. canadensis) against Staphylococcus aureus by inhibition of the NorA multidrug resistance pump. |
| CFN98181 | trans-3-Hydroxycinnamic acid 3-Hydroxycinnamic acid, also known as m-coumaric acid, is an aromatic acid that can be found in vinegar. 3-Hydroxycinnamic acid has antioxidant activity. |
| CFN98182 | 3,4,5-Trimethoxycinnamic acid 3,4,5-Trimethoxycinnamic acid has anti-stress effect, prolonging the sleeping time in animals. 3,4,5-Trimethoxycinnamic acid may exert anti-seizure activity by acting at the GABAA/BZ receptor complex. It shows hypoxia inducible factor-2 (HIF-2) inhibitory activity with EC50 value of 60.6 uM. 3,4,5-Trimethoxycinnamic acid derivatives have a potential antinarcotic effect through acting as a 5-HT(1A) receptor agonist in mice. |
| CFN98183 | 4-(Dimethylamino)cinnamic acid 4-(Dimethylamino)cinnamic acid (DMACA) could be as charge transfer (ICT) probe. |
| CFN98184 | 4-Chlorocinnamic acid 4-Chlorocinnamic acid is a photosensitive compound. 2-Chlorocinnamic acid and 4-chlorocinnamic acid show potent urease inhibitory activities with the respective IC50 values of 0.66 and 1.10 uM. |
| CFN98185 | 4-Nitrocinnamic acid 4-Nitrocinnamic acid is a photosensitive compound. 4-Nitrocinnamic acid has inhibitory effects on tyrosinase. |
| CFN98186 | 4-Methylcinnamic acid 4-Methylcinnamic acid is a photosensitive compound. |
| CFN98187 | 2-(Acetylamino)-3-phenyl-2-propenoic acid Reference standards. |
| CFN98188 | trans-4-(Trifluoromethyl)cinnamic acid trans-4-(Trifluoromethyl)cinnamic acid is a photosensitive compound. |
| CFN98189 | trans-2,3,4-Trimethoxycinnamic acid Reference standards. |
| CFN98190 | 2-Chlorocinnamic acid 2-Chlorocinnamic acid is a photosensitive compound, it can inhibit tyrosinase activity. 2-Chlorocinnamic acid and 4-chlorocinnamic acid show potent urease inhibitory activities with the respective IC50 values of 0.66 and 1.10 uM. |
| CFN98395 | Eucalyptin Eucalyptin has antioxidant and antimicrobial properties, it exhibits potent antimicrobial activities against seven micro-organisms with minimum inhibitory concentrations (MIC) ranging from 1.0 to 31 mg/L. Eucalyptin A exhibits potent inhibition on HGF/c-Met axis. |
| CFN98396 | gamma-Mangostin gamma-Mangostin is a dual agonist that activates both PPARδ and PPARα, is also a novel competitive antagonist for the 5-HT2A receptors in vascular smooth muscles and platelets.gamma-Mangostin has free radical scavenging activity, and antiproliferative and apoptotic activity in HepG2 cells, and exhibits antihypertensive, anti-inflammatory, analgesic effects. gamma-Mangostin could as a preventive agent of the metabolic syndrome, and could serve as a micronutrient for colon cancer prevention. |
| CFN98397 | Arjunic acid Arjunic acid is a strong antioxidant and a free radical scavenger. Arjunic acid shows activity against Gram-positive and Gram-negative bacteria with MIC values ranging between 1.9 and 15.6 microg/mL. |
| CFN98398 | Isotachioside Isotachioside has15-lipoxygenase (15-LO) inhibitory activities. |
| CFN98399 | Sutherlandin trans-p-coumarate Sutherlandin trans-p-coumarate is a naturally rare cyanogenic glycoside. |
| CFN98400 | Isobavachin Isobavachin can stimulate osteoblasts proliferation and differentiation; it also can facilitate mouse embryonic stem cells differentiating into neuronal cells, the mechanism involved protein prenylation and, subsequently, phos-ERK activation and the phos-p38 off pathway. Isobavachin possesses estrogen-like activity in MCF-7/BOS cells, it can significantly stimulate the proliferation of MCF-7/BOS cells in a dose-dependent manner. Isobavachin has cytotoxic effects on H4IIE hepatoma and metabolically poorly active C6 glioma cells. |
| CFN98401 | 1,18-Octadecanediol Reference standards. |
| CFN98402 | Heraclenol Heraclenol is a germination inhibitor in the parsley seeds. It has anti-inflammatory properties against the ear edema in mice produced by TPA. Heraclenol and heraclenin inhibit the proliferation of melanoma cells and cell cycle at G2/M at concentrations of 0.1-1.0 uM. |
| CFN98403 | 6-Methoxywogonin 6-Methoxywogonin shows weak anti-inflammatory effect. |
| CFN98404 | Pinusolide Pinusolide is a platelet activating factor ( PAF) antagonist, it may prove of therapeutic value in the treatment of hypotension, it has antileukemic potential, and could be used to treat neurodegenerative diseases. Pinusolide attenuates blockade of insulin signaling by enhancing IRS-1 tyrosine phosphorylation by the activating the AMPK pathway, indicates the targeting of AMPK represents a new therapeutic strategy for hyperglycemia-induced insulin resistance and type 2 diabetes. |
| CFN98405 | Hesperetin 7-O-glucoside Hesperetin 7-O-glucoside and prunin are direct precursors of naringin and neohesperidin, respectively, in C. aurantium. Hesperetin 7-O-glucoside shows inhibition of human HMG-CoA reductase, it also exhibits effective inhibition of the growth of Helicobacter pylori. Hesperetin 7-O-glucoside can reduce blood pressure in healthy volunteers. |
| CFN98406 | Methyl orsellinate Methyl orsellinate is a phytotoxic compound, it exhibits antifungal activity, it can cause significant inhibition of radicle growth of Amaranthus hypochondriacus and Echinochloa crus-galli, interact with bovine-brain calmodulin and inhibit the activation of the calmodulin-dependent enzyme cAMP phosphodiesterase. Methyl orsellinate can inhibit PTP1B activity with 50% inhibitory concentration values of 277 +/- 8.6 microM, the selective inhibition of PTP1B has been widely recognized as a potential drug target for the treatment of type 2 diabetes and obesity, methyl orsellinate may can treat the type 2 diabetes and obesity. |
| CFN98407 | Ethyl glucoside Ethyl glucoside is a shale inhibitor for water base drilling fluids. It is also a multifunctional initiator for enzyme-catalyzed regioselective lactone ring-opening polymerization. |
| CFN98408 | Marmin acetonide Reference standards. |
| CFN98409 | 1,10:4,5-Diepoxy-7(11)-germacren-8-one Reference standards. |
| CFN98410 | Heraclenol 3'-O-beta-D-glucopyranoside Reference standards. |
