Natural Products
| Catalog No. | Information |
| CFN97338 | 4-Hydroxycephalotaxine 4-Hydroxycephalotaxine is a natural product from Cephalotaxus fortunei. |
| CFN97339 | Rocaglamide Rocaglamides are potent natural anticancer products that inhibit proliferation of various cancer cells at nanomolar concentrations, it prevents tumor growth and sensitize resistant cancer cells to apoptosis by blocking the MEK-ERK-eIF4 pathway. Rocaglamides can suppress the PMA-induced expression of NF-kappaB target genes and sensitize leukemic T cells to apoptosis induced by TNFalpha, cisplatin, and gamma-irradiation, suggests that rocaglamide derivatives could serve as lead structures in the development of anti-inflammatory and tumoricidal drugs. Rocaglamide and a XIAP inhibitor cooperatively sensitize TRAIL-mediated apoptosis in Hodgkin's lymphomas. |
| CFN97400 | Cleomiscosin C Cleomiscosin C has antioxidant activity, it protects against the oxidative modification of apoB-100 induced by either Cu2+ or HOCl ( IC50s of 23.6 and 3.9 microM, respectively), suggests that it could be beneficial in preventing LDL oxidation in atherosclerotic lesions. Cleomiscosins A, B and C exhibit liver-protective properties. |
| CFN97401 | Qingyangshengenin Qingyangshengenin is a a glycoside from the roots of Cynanchum otophyllum. |
| CFN97402 | Eriocalyxin B Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways, should be considered a candidate for pancreatic cancer treatment; it is a specific inhibitor of STAT3, it directly targets STAT3 through a covalent linkage to inhibit the phosphorylation and activation of STAT3 and induces apoptosis of STAT3-dependent tumor cells. Eriocalyxin B exerts potent antiinflammatory effects through selective modulation of pathogenic Th1 and Th17 cells by targeting critical signaling pathways. Eriocalyxin B reversibly interfer with the binding of p65 and p50 subunits to the DNA in a noncompetitive manner. |
| CFN97403 | Lapachol Lapachol shows both antimicrobial, trypanocidal and antiviral activities, it also shows antimalarial activity against Plasmodium falciparum in vitro and Plasmodium berghei in vivo. Probiotics are capable of converting Lapachol into the most effective cytotoxic compound against a breast cancer cell line. |
| CFN97404 | 5-Epilithospermoside (-)-5-Epilithospermoside is proposed as a potential marker of botanical origin for phacelia honey. |
| CFN00430 | Crotaverrine Reference standards. |
| CFN00431 | Swazine Swazine is a natural product from Senecio swaziensis. |
| CFN00432 | Syneilesine Reference standards. |
| CFN97405 | 3,4-Dimethoxyphenyl beta-D-glucoside Reference standards. |
| CFN97406 | Vasicinolone Vasicinolone has anti-inflammatory, and antimicrobial activities. |
| CFN97407 | Stigmasta-4,25-dien-3-one Reference standards. |
| CFN97408 | Stigmasta-4,22,25-trien-3-one Stigmasta-4,22,25-trien-3-one is a natural product from Callicarpa giraldiana. |
| CFN97409 | Chinensine B Chinensine B and Chinensines A, C, D and Ε are antitumor diterpenoids. |
| CFN97410 | Cudraxanthone B Cudraxanthone B is a natural product from Cudrania tricuspidata. |
| CFN97411 | Norviburtinal Norviburtinal possesses novel angiogenesis effect. Norviburtinal and isopinnatal show in vitro cytotoxicity against cancer cell lines, norviburtinal has little selectivity for melanoma cell lines whilst isopinnatal also shows some cytotoxic activity. |
| CFN97412 | 2-Methoxystypandrone 2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-κB signaling to limit the inflammation and oxidative stress for preservation of BBB integrity. 2-Methoxystypandrone concomitantly promotes neurodevelopmental protein expression and endogenous neurogenesis through inactivation of GSK3β to enhance β-catenin signaling for upexpression of neuroprotective genes and proteins.2-Methoxystypandrone has anti-osteoclastogenic effect, could reflect the block of RANKL-induced association of TRAF6-TAK1 complexes with consequent decrease of IkappaB-mediated NF-kappaB and mitogen-activated protein kinases-mediated c-Fos activation pathways and suppression of NFATc1 and other gene expression, essential for bone resorption. |
| CFN00433 | Trichodesmine Trichodesmine has greater lethality and neurotoxicity than monocrotaline, because of the two structural characteristics:(a) steric hindrance at position 14 of dehydroTrichodesmine results in greater resistance to hydrolysis, allowing more to be released from the liver and to be delivered to the brain;(b) the larger isopropyl substituent at position 14 of dehydroTrichodesmine renders the molecule more lipophilic, leading to greater penetration of the brain. |
| CFN97413 | Heteronoside Reference standards. |
| CFN97414 | Sculponeatin A Sculponeatin A is a natural product from Rabdosia amethystoides. |
| CFN97415 | Hythiemoside A Reference standards. |
| CFN97416 | Trichorabdal A Trichorabdal A shows a very strong in vitro antibacterial activity against Helicobacter pylori. |
| CFN00434 | Isoammodendrine Reference standards. |
| CFN00435 | N'-Methylammodendrine N'-Methylammodendrine is a natural product from Lupinus formosus. |
| CFN00436 | Anabasamine Reference standards. |
| CFN97417 | 5,19-Epoxy-19S,25-dimethoxycucurbita-6,23-dien-3-ol Reference standards. |
| CFN97418 | Eupatorin Eupatorin has antiproliferative and antiangiogenic effects, it emerges as a promising agent in anticancer research.Eupatorin-induced cell death is mediated by both the extrinsic and the intrinsic apoptotic pathways and through a mechanism dependent on reactive oxygen species generation. Eupatorin also has meaningful anti-inflammatory property which may be utilized in the development of novel anti-inflammatory treatments. |
| CFN97419 | Curculigoside Curculigoside has potent antioxidant, anti-osteoporotic, immunomodulatory, and neuroprotective effects. Curculigoside can improve cognitive function in aged animals, possibly by decreasing the activity of AchE in the cerebra and inhibiting the expression of BACE1 in the hippocampus. Curculigoside exhibits potent inhibitory activity against matrix metalloproteinase-1 in cultured human skin fibroblasts, and increases the levels of ALP and Runx2 in osteoblasts under oxidative stress via anti-oxidative character. |
| CFN97420 | alpha-Conidendrin Reference standards. |
| CFN00437 | Antibiotic PF 1018 Antibiotic PF 1018 is an insecticidal agent. |
| CFN00438 | Astrocasine Astrocasine is a natural product from Carduus acanthoides L. |
| CFN00439 | Astrophylline Reference standards. |
| CFN97421 | Longistylumphylline A Standard reference |
| CFN97422 | prim-O-Glucosylangelicain prim-O-Glucosylangelicain is a natural product from Cimicifuga foetida L. |
| CFN97423 | alpha-Amyrin acetate Alpha-Amyrin acetate has anti-inflammatory, antispasmodic profile and the relaxant effects. It can decrease blood engorgement time and feeding rate and decline fecundity which reduce the overall survival and reproductive capacity of the malaria vector A. stephensi. The oral administration of alpha-Amyrin acetate can significantly improve the diabetic condition in streptozotocin-induced diabetic rats and in diabetic db/db mice at 50 mg kg(-1) dose level. |
| CFN97424 | Nigrolineaxanthone V Standard reference |
| CFN00440 | Isonicoteine Reference standards. |
| CFN00441 | Aspertine C Reference standards. |
| CFN00442 | Cassipourine Cassipourine and gerrardine show antibacterial activity. |
| CFN97425 | N-Methylcalycinine N-Methylcalycinine exhibits potent AChE inhibitory activity. |
| CFN97426 | Ganoderic acid SZ Reference standards. |
| CFN97427 | 6-Benzoyl-5,7-dihydroxy-2,2-dimethylchromane Reference standards. |
| CFN97428 | Clausine Z Clausine Z exhibits inhibitory activity against cyclin-dependent kinase 5 (CDK5) and shows protective effects on cerebellar granule neurons in vitro. |
| CFN00443 | Gramodendrine Gramodendrine and ammodendrine are moderately potent (300 mg/kg, ip) in reducing spontaneous motor activity (30% of control) and in causing central nervous system depression (50% of control). spect. |
| CFN00444 | Lobelanidine Lobelanidine is a chemical constituent from from Lobelia chinensis Lour, Lobelia chinensis Lour possesses a number of pharmacological activities (e.g., diuretic, choleretic, breathing excitement, anti-venom, anti-bacterial, and anticancer). |
| CFN00445 | Lobelin Inhalation challenge with capsaicin and rapid intravenous injection of Lobelin and alinamin indicated that peripheral c-fiber receptors were involved in the induction of coughing. |
| CFN97429 | 7-Hydroxy-3-prenylcoumarin Reference standards. |
| CFN97430 | 2,2,5,5-Tetramethylcyclohexane-1,4-dione Reference standards. |
| CFN97431 | threo-Guaiacylglycerol beta-coniferyl ether Threo-Guaiacylglycerol beta-coniferyl ether displays significant inhibitory effects on NO production. |
