Natural Products
| Catalog No. | Information |
| CFN97552 | Paniculidine A Paniculidine A is a natural product from Murraya exotica L. |
| CFN97553 | Paniculidine B Standard reference |
| CFN97554 | Paniculidine C Standard reference |
| CFN90215 | (+)-Isocorynoline Reference standards. |
| CFN90216 | Rhmannioside D Reference standards. |
| CFN90217 | Turkesterone Turkesterone is a phytoecdysteroid possessing an 11alpha-hydroxyl group, also is an analogue of the insect steroid hormone 20-hydroxyecdysone. It has immunomodulating and antistress activity, can increase the adaptation capacity of mice under immobilization-induced stress conditions. |
| CFN90218 | Corynoxine Corynoxine is a natural autophagy enhancer, promotes the clearance of Alpha-synuclein via Akt/mTOR pathway, it can significantly inhibit the oxidative stress of PC12 cells. |
| CFN97555 | Cycloart-22-ene-3,25-diol Cycloart-22-ene-3,25-diol shows tyrosinase inhibitory activity, the IC50 value of 77.5 uM . |
| CFN97556 | 5-O-Methylhierochin D Reference standards. |
| CFN97557 | Allantoin Allantoin, as I-1R agonist, has the potential to develop as a new therapeutic agent for hypertension. Allantoin has memory-enhancing, anti-oxidative and anti-inflammatory activities; it can enhance the antifungal activity of Nanoencapsulation. Allantoin is a skin conditioning agent that promotes healthy skin, stimulates new and healthy tissue growth. Allantoin mediates PI3K-Akt-GSK-3β signal pathway. |
| CFN97558 | 3,4'-Dihydroxy-3,5',7-trimethoxyflavan Reference standards. |
| CFN90219 | 1-O-Acetyl britannilactone 1-O-Acetyl britannilactone shows antifungal, and anti-cancer activities, it suppresses angiogenesis and lung cancer cell growth possibly via regulating the VEGFR-Src-FAK signaling. 1-O-Acetyl britannilactone may be one anti-inflammatory drug which inhibits the expression of COX-2 gene by blocking NF-κB activation and thus suppresses the inflammatory response to LPS in vascular smooth muscle cells. |
| CFN90220 | Britannin Britannin has strong cytotoxicity to HepG-2, MCF-7, MDBK and A-549 cells (IC50: 2.2, 5.9, 5.4, and 3.5 microg/mL, respectively). Britannin inhibits growth of MCF-7 and MDA-MB-468 breast cancer cells through the activation of the mitochondrial apoptotic pathway and may potentially serve as an agent for breast cancer therapy. |
| CFN90221 | Beta-boswellic acid Beta-boswellic acid and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemic activities. Beta-boswellic acid can significantly enhance neurite outgrowth, branching, and tubulin polymerization dynamics. |
| CFN90222 | Allomatrine Allomatrine can inhibit proliferation and invasion in vitro of human lung cancer A549 cell line by inducing ROS production,promoting apoptosis, arresting cell cycle, inhibiting ubiquitin proteasome and regulating tumor related gene expression. (+)-Allomatrine and (+)-matrine when given i.c.v. may stimulate the descending dynorphinergic neuron, resulting in the stimulation of KORs in the spinal cord, and this phenomenon in turn produces the antinociception in mice. |
| CFN97559 | Methyl 3-carbazolecarboxylate Methyl 3-carbazolecarboxylate is a natural product from Micromelum sp. |
| CFN97560 | Leachianone A Leachianone A is a potential antitoxic agent, it shows inhibitory effects on cadmium- Induced cytotoxicity. Leachianone A exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2); leachianone A also possesses a profound cytotoxic activity against human hepatoma cell line HepG2 in vitro, with an IC(50) value of 3.4microg/ml post-48-h treatment, its action mechanism via induction of apoptosis involved both extrinsic and intrinsic pathways. |
| CFN97561 | Ailanthone Ailanthone has anti-inflammatory, anti-HIV, anti-malarial, anti-allergic, antiulcer and antimicrobial activities; it also has potent antineoplastic activity against hepatocellular carcinoma (HCC), it can inhibit huh7 cancer cell growth via cell cycle arrest and apoptosis in vitro and in vivo. Ailanthone has significant pre-emergence herbicide activity , is directly correlated to Ailanthone concentration. |
| CFN97562 | Isothymusin Isothymusin( MIC= 200 microg/mL) exhibits inhibition activity against Mycobacterium tuberculosis. It ( IC50=7.7 microg/mL ) exhibits antioxidant activity against the radical scavenging ability of DPPH. |
| CFN90223 | Salvianolic acid D Salvianolic acid and notoginseng triterpenes can promote EA-hy926 and expression of protein, have protective effects on angiogenesis in EA-hy926 cells in vitro. |
| CFN90224 | Ligustroflavone Ligustroflavone shows high antioxidant capacity and is reported to be an AMPK activator, it activates AMPK by increasing ratio of AMP / ATP and promotes adiponectin multimerization by activating AMPK. |
| CFN90225 | Trigonelline Trigonelline (1-methylpyridinium-3-carboxylate), an alkaloid present in coffee and fenugreek seed, exhibits phytoestrogenic, anti-adipogenesis, and anticancer activities, it also can reduce early glucose and insulin responses. Trigonelline has inhibition of the Nrf2 transcription factor and PPAR-γ. |
| CFN90226 | Croceic acid Croceic acid is a singlet oxygen quencher. |
| CFN97563 | 3-(4-Hydroxy-3-methoxyphenyl)propyl tetracosanoate Reference standards. |
| CFN97564 | Limonol Limonol-derivatives could as promising scaffolds for the design of novel Hsp90α inhibitors. |
| CFN97565 | Limonexic acid Limonexic acid shows antinociceptive actions , it produces dose-related inhibition of glutamate- and capsaicin-induced pain. Limonexic acid can effectively protect hepatocyte against CCl4-induced injury. |
| CFN97566 | Prunasin Prunasin is a kind of enzyme inhibitors. |
| CFN90227 | Crocin Crocin is a water-soluble carotenoid pigment of saffron (Crocus sativus L.), it has been used as a spice for flavoring and coloring food preparations. Crocin has anti-inflammatory, anti-oxidative, anti-apoptotic, anti-asthma, anti-cancer, and hypolipidemic effects. Crocin improves toxic effects of diazinon via reducing lipid peroxidation and restoring altered contractile and relaxant responses in rat aorta; it also protects retinal photoreceptors against light-induced cell death. Crocin can also promote ovarian cancer HO-8910 cell apoptosis, most likely by increasing p53 and Fas/APO-1 expression, and then activating the apoptotic pathway regulated by Caspase-3. |
| CFN90228 | Bullatine A Bullatine A possesses anti-rheumatic, anti-inflammatory and anti-nociceptive effects, may be used for the treatment of neurodegenerative diseases such as arthritis. Bullatine A produces antinociception without induction of tolerance and inhibits morphine antinociceptive tolerance, and provide pharmacological basis for concurrent bullatine A and morphine treatment for chronic pain and morphine analgesic tolerance. |
| CFN90229 | Bullatine B |
| CFN90230 | Vinblastine Vinblastine is a cytotoxic alkaloid used against various cancer types. Vinblastine inhibits the formation of microtubule and suppresses nAChR with an IC50 of 8.9 μM.Vinblastine potently induced the proapoptotic protein PMAIP1 (NOXA) in both time- and dose-dependent manner and this was required for the observed apoptosis.The combination of antifungal azoles with Vinblastine can increase the incidence and severity of hyponatremia. Therefore, combined administration of azole antifungals with Vinblastine should be avoided. |
| CFN97567 | Methyl rosmarinate Methyl rosmarinate shows antioxidative, and antifungal activities. It has inhibitory activities against tyrosinase, α-glucosidase, and matrix metalloproteinase-1 (MMP-1). |
| CFN97568 | 3,4-Dihydroxybenzoic acid 3,4-Dihydroxybenzoic acid shows significant nematicidal, antitumor, neuroprotective, antioxidant, and antimicrobial activities. 3,4-Dihydroxybenzoic acid has protection against adriamycin cytotoxicity and inhibition of DNA topoisomerase II activity; it also protects human keratinocytes against UVB-induced oxidative stress and apoptosis.3,4-Dihydroxybenzoic acid can prevent Abeta (25-35)-induced neuronal cell damage by interfering with the increase of [Ca(2+)](c), and then by inhibiting glutamate release, generation of ROS and caspase-3 activity. |
| CFN97569 | Kazinol B Kazinol B inhibits the NO synthesis with an IC(50) of 21.6 microM. It can stimulate respiratory burst, is probably mediated by the synergism of PKC activation and [Ca2+]i elevation in rat neutrophils. Kazinol B stimulates Ca(2+) release from internal Ca(2+) store, probably through the sphingosine 1-phosphate and IP(3) signaling, and activates external Ca(2+) influx mainly through a non-store-operated Ca(2+) entry (non-SOCE) pathway. Kazinol B improves insulin sensitivity via Akt and AMPK activation in 3T3-L1 adipocytes, it might be a therapeutic candidate for diabetes mellitus. |
| CFN97570 | Scholaricine Scholaricine reverses multidrug resistance in vincristine-resistant KB cells. |
| CFN90231 | Isobergapten Isobergapten is a plant growth regulating substance, it is the principal constituents responsible for the antimycobacterial activity of the roots of Heracleum maximum; it may form an important class of natural defensive agents against fungi.Isobergapten shows anti-proliferative activity and causes G2/M arrest at concentrations of 0.05-15.0 μM. |
| CFN90232 | Nodakenin Nodakenin acts as an AChE inhibitor that inhibits AChE activity in a dosedependent manner with an IC50 value of 84.7 μM. Nodakenin possesses neuroprotective, anti-allergic, antiaggregatory, antibacterial, and memory -enhancing effects. Nodakenin down-regulates the expression of the proinflammatory iNOS, COX-2, TNF-α, IL-6, and IL-1β genes in macrophages by interfering with the activation of TRAF6, thus preventing NF-κB activation. |
| CFN97571 | Methyl 4-hydroxybenzoate Methyl 4-hydroxybenzoate is an anti-fungal agent often used in a variety of cosmetics, personal-care products and food preservatives. |
| CFN97572 | Kaempferol 3-O-arabinoside Kaempferol-3-O-α-D-arabinoside displays cytotoxic and high antioxidant activity.Kaempferol-3-O-arabinoside and kaempferol-3-O-glucoside can function as antioxidants in biological systems, particularly skin exposed to UV radiation by scavenging ROS, and protect cellular membrane against ROS; they can be applicable to new cosmeceuticals for antioxidant, antiaging, and antibacterial activity. |
| CFN97573 | Isoboonein acetate Reference standards. |
| CFN97574 | Bullatantriol Bullatantriol has a stimulative effect on significantly proliferation and differentiation of culture osteoblasts. It may have weak antibacterial activities. |
| CFN97575 | 4'-Hydroxyacetophenone 4'-Hydroxyacetophenone is a potent xanthine oxidase inhibitor, three 4′-hydroxyacetophenone-related phytoalexins from Polymnia sonchifolia have antifungal activity. |
| CFN97576 | Isoboonein Isoboonein exhibits significant antitumor and antibacterial activity. |
| CFN97577 | 4-Hydroxybenzoic acid 4-Hydroxybenzoic acid, also known as p-hydroxybenzoic acid (PHBA), is a phenolic derivative of benzoic acid and widely used in organic synthesis. 4-Hydroxybenzoic acid derivatives has potential to as pan-HDAC inhibitors with anticancer properties. 4-Hydroxybenzoic acid positively regulates the expression of gum cluster to promote EPS production in PXO99A; it can inhibit most gram-positive and some gram-negative bacteria, with an IC50 of 160 μg/mL. |
| CFN97578 | 2,3-Di-O-methylthiomethyleuscaphic acid Reference standards. |
| CFN97579 | 7-O-Demethyl-3-isomangostin hydrate Reference standards. |
| CFN97580 | 9-Hydroxycalabaxanthone hydrate The combination of 9-hydroxycalabaxanthone with α-mangostin showed the synergistic antimalarial interaction in both clones. |
| CFN97581 | 8-Isomulberrin hydrate Reference standards. |
| CFN97582 | 3-(3-Hydroxy-3-methylbutanyl)-2,4,6-trihydroxybenzophenone Reference standards. |
| CFN97583 | 6'-Hydroxy-7'-ethoxybergamottin Reference standards. |
