ChemFaces Product List

Catalog No.	Information
CFN00261	Symlandine Symlandine, 7-acetylintermedine, and 7-acetyllycopsamine are pyrrolizidine alkaloids, isolated from comfrey, can produce hepatotoxicity in livestock and humans and carcinogenicity in experimental animals.
CFN00262	Symphytine Symphytine and senkirkine, the pyrrolizidine alkaloids, have carcinogenicity.
CFN00263	1,2-Epoxy-1-hydroxymethylpyrrolizidine Reference standards.
CFN00264	Europine Europine shows both antifungal and insect antifeedant activity.
CFN00265	Europine N-oxide Supinine, lasiocarpine-N-oxide and Europine N-oxide exhibit virucidal activity to Poliomyelitis, Coxsackie, Semliki forest, Vesicular stomatitis and Herpes simplex at the concentration of 5, 10 and 20 mu g/ml respectively.
CFN97157	2,3,2'',3''-Tetrahydroochnaflavone Standard reference
CFN97158	Ethyl 2,4-dihydroxyphenylacetate Reference standards.
CFN97159	Martynoside Martynoside is a natural selective estrogen receptor modulator, which has antioxidative, anti-muscle fatigue, anticancer and antimetastatic activities. Martynoside has the potential of antagonizing sports anaemia, the mechanism of this effect might be related to preventing RBC from free radical damage.
CFN97160	Trifolirhizin Trifolirhizin possesses potential anti-inflammatory and anti-cancer activities, it inhibits acetylcholine mediated airway smooth muscle (ASM) contraction or directly relaxes pre-contracted ASM independent of β 2 -adrenoceptors. Trifolirhizin may be a a candidate as skin-whitening agents, it exerts varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis.
CFN97161	4',5,7-Trihydroxy-6-prenylflavone 6-Prenylapigenin(4',5,7-Trihydroxy-6-prenylflavone) shows potent inhibitory activity on melanin formation, it may be potential sources for skin whitening agents. It also shows moderate cytotoxicities against breast cancer (MDA-MB-435S) and lung adenocarcinoma (A549) cell lines.
CFN97162	Chonglou Saponin VII Chonglou saponin VII shows inhibitory effects on cell proliferation.
CFN97163	Nortetraphyllicine Nortetraphyllicine is a natural product from Rauvolfia verticillata.
CFN97164	Imbricatolic acid Imbricatolic acid can prevent cell cycle progression in p53-null CaLu-6 cells.
CFN97165	6',7'-Dihydroxybergamottin acetonide 6',7'-Dihydroxybergamottin is a potent inhibitor of CYP3A activity, and may be primarily responsible for the effects of grapefruit juice on cytochrome P450 activity in humans.
CFN97166	Isowighteone Isowighteone, a compound that is not naturally produced in this species, accumulated by medicago truncatula hairy roots expressing LaPT1, indicates a strategy for metabolic engineering of novel antimicrobial compounds in legumes; it may have antimicrobial activity against fungal pathogens of plants.
CFN97167	Prometaphanine Reference standards.
CFN97168	Echitamine Echitamine chloride possesses anti-tumour activity in-vitro and in-vivo.
CFN97169	Xanthoplanine Xanthoplanine fully inhibits the EC(50) ACh responses of both alpha7 and alpha4beta2 nACh receptors with estimated IC(50) values of 9+/-3 microM (alpha7) and 5+/-0.8 microM (alpha4beta2).
CFN00266	Latifoline Reference standards.
CFN00267	Latifoline N-oxide Latifoline N-oxide is a natural product from Hackelia floribunda.
CFN00268	Heliosupine Heliosupine, heliosupine N-oxide, 3 ′-O-acetylheliosupine N-oxide,and 7-O- angeloylechinatine N-oxide show inhibition activity against the acetylcholinesterase(AChE), with IC50 0.53-0.60 mM. Heliosupine can deter feeding by the polyphagous larvae of Spodoptera exigua.
CFN00269	Acetylheliosupine Reference standards.
CFN00270	Heliotrine The pyrrolizidine alkaloid Heliotrine interferes with reporter signals derived from GAL4-based nuclear receptor transactivation assays by a mechanism independent of luciferase enzyme inhibition. Acute hepatitis induced by Heliotrine is accompanied by uncoupling of oxidative phosphorylation in liver mitochondria.
CFN97170	4-Oxobedfordiaic acid Reference standards.
CFN97171	6-Acetyl-2,2-dimethylchroman-4-one 6-Acetyl-2,2-dimethylchroman-4-one and vanillin show anti-platelet aggregation activity induced by arachidonic acid in vitro.
CFN97172	Sophoridine Sophoridine has anti-inflammatory, anti-cancer and anti-arrhythmia, and affects the immune and central nervous systems. Early and short-time applying sophoridine has neuroprotective effect min permanent middle cerebral artery occlusion (pMCAO) rat brain by down-regulating TRAF6 and up-regulating p-ERK1/2 expression, ameliorating brain infaction and edema. Sophoridine also possesses antiviral activities against Coxsackievirus B3, by regulating cytokine expression, may represent a potential therapeutic agent for viral myocarditis.
CFN97173	Sempervirine Sempervirine can unwind circular DNA, it shows selective inhibition of in vitro synthesis of cancer DNA .
CFN97174	4-Epi-isoinuviscolide Standard reference
CFN97175	Eburicol Mutations in the Eburicol gene impact on the activity of the Eburicol protein. Eburicol inhibit the large accumulation of C-14 methyl sterols and cell lysis when the content of ergosterol becomes too low in the actively growing cells.
CFN97176	2-Caren-10-ol 2-Caren-10-al may have antioxidant, antibacterial and antifungal activities.
CFN97177	16-Hydroxy-8(17),13-labdadien-15,16-olid-19-oic acid 16-Hydroxy-8(17),13-labdadien-15,16-olid-19-oic acid may show a strong algicidal activity against Raphidocelis subcapitata.
CFN97178	Moracin C Moracin C and D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin C has potent antibacterial activity, it can inhibit FabI and fatty acid synthesis, it inhibit S. aureus FabI with IC(50) of 83.8 uM. Moracin C has anti-inflammatory effect, it can effectively reduce lipopolysaccharide (LPS) stimulated up-regulation of mRNA and protein expression of iNOS, COX-2, and serval pro-inflammatory cytokines (IL-1β, IL-6 and TNF-α).Moracin may be protective influence in tumor promotion, utilization of Moracin may open a new avenue in the treatment of tumerigenesis.
CFN97179	Moracin D Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin may be protective influence in tumor promotion, utilization of Moracin may open a new avenue in the treatment of tumerigenesis.
CFN00271	Heliotrine N-oxide Heliotrine N-oxide was used as an internal standard.
CFN00272	Tussilagine Reference standards.
CFN00273	Isotussilagine Reference standards.
CFN00274	Pyrrolam B Pyrrolam B is a natural product from Streptomyces olivaceus.
CFN00275	Macrophylline Macrophylline A shows weak inhibitory action on KCl-induced contraction.
CFN97180	Pinoresinol 4-O-beta-D-glucopyranoside (+)-Pinoresinol 4-O-beta-D-glucopyranoside revealed that the presence of a vanilloyl group in the sugar moiety of (+)-pinoresinol 4-O-[6″-O-vanilloyl]-β-D-glucopyranoside is crucial for its anti-influenza virus activity.
CFN97181	8-O-Acetylharpagide 8-O-Acetylharpagide has anti-inflammatory, vasoconstrictor, antibacteria and antiviral activities, it also has a biological activity on isolated smooth muscle preparations from guinea pig. 8-O-Acetylharpagide presents the obvious inhibition on Epstein-Barr virus(EBV) infection, it not only apparently inhibits EBV-VCA,but also alleviates the hyperfunction and effusion of capillary permeability at the early inflammation.
CFN97182	Tupichilignan A Reference standards.
CFN97183	4-(3,4-Dimethoxyphenyl)-3-buten-1-ol (E)-4-(3,4-dimethoxyphenyl)but-3-en-1-ol may promote melanin synthesis via USF1 dependent fashion and could be used as a clinical therapeutic agent against hypopigmentation-associated diseases.
CFN97184	2,7-Dihydroxy-2H-1,4-benzoxazin-3(4H)-one Standard reference
CFN00276	Petasinine Reference standards.
CFN00277	Petasinoside Petasinoside is a natural product from Petasites japonicus.
CFN00278	Thesinine Reference standards.
CFN00279	Trachelanthamidine Reference standards.
CFN00280	Laburnine Reference standards.
CFN97185	Bourjotinolone A Standard reference
CFN97186	Isocostic acid Isocostic acid may have antibacterial activity.

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