ChemFaces Product List

Catalog No.	Information
CFN92264	Rabdosin B Rabdosin B shows cytotoxic activity against three human tumour HepG2, GLC-82 and HL-60 cell lines, it induces significant DNA damage to HepG2 cells in a time- and dose-dependent manner. Rabdosin B at higher concentrations inhibits root growth by affecting both cell length in the mature region and division of meristematic cells.
CFN90500	4'-O-Methylvitexin Reference standards.
CFN92265	cis-Tiliroside Kaempferol-3-O-β-D-(6''-O-coumaryl) glycoside has antioxidant activity and α-glucosidase inhibitory effects, it could potentially be used for food additives and the development of useful natural compounds.
CFN92266	Dulcoside A Dulcoside A is a sweetener and has antioxidant activity.
CFN92267	Platycoside M1 Reference standards.
CFN92268	Platyconic acid A Platyconic acid A suppresses the development of respiratory inflammation, hyperresponsiveness, and remodeling by reducing allergic responses, and it may be a potential herbal drug for allergen-induced respiratory disease prevention. Platyconic acid A suppresses PMA-induced MUC5AC mRNA expression by inhibiting NF-κB activation via Akt in A549 cells.
CFN92269	Deapi-platycodin D3 Deapi-platycodin and platycodinD, aqueous extract of the root of Platycodon grandiflorum A. de Candolle (APG), can regulate the production and secretion of airway mucin and, at least in part, explains the traditional use of aqueous extract of APG as expectorants in diverse inflammatory pulmonary diseases.
CFN92270	Platycoside A Platycoside A has hemolytic activity and adjuvant potential on the immune responses to Newcastle disease virus-based recombinant avian influenza vaccine. It induces the IgG and IgG1 antibody responses in the immunized mice.
CFN92271	Platycoside K Reference standards.
CFN92272	Platycoside M3 Reference standards.
CFN92273	Ilexside I Reference standards.
CFN92274	Jacoumaric acid Jacoumaric acid is a lead molecule from the library or database of natural compounds as a HIV-1 protease inhibitor.
CFN92275	Eucalyptolic acid Eucalyptolic acid is a natural product from Eucalyptus globulus.
CFN92276	Methyl (E)-3'-hydroxy-4'-methoxycinnamate Reference standards.
CFN92277	Schisanlactone D Schisanlactone D is a natural product from Kadsura longipedunculata Finet.et Gagnep.
CFN92278	Rubrisandrin A Rubrisandrin A is an anti-HIV agent.
CFN92279	Chrysin 7-O-beta-D-glucopyranuronoside Reference standards.
CFN92280	Glychionide A Reference standards.
CFN92281	Beta-D-glucopyranosiduronic acid Reference standards.
CFN92282	Oroxylin A 7-O-beta-D-glucuronide methyl ester Oroxylin A 7-O-beta-D-glucuronide methyl ester possibly possesses the potential immune activities.
CFN92283	Baicalin methyl ester Baicalin methyl ester shows inhibitory effects on the Avian Myeloblastosis Virus reverse transcriptase (AMV-RT).
CFN92284	Chrysin 6-C-arabinoside 8-C-glucoside Chrysin-6-C-arabinosyl-8-C-glucoside and chrysin-6-C-glucosyl-8-C-arabinoside are α-glucosidase inhibitors, α-glucosidase inhibitors are widely used in the treatment of type 2 diabetes.
CFN92285	Chrysin 6-C-glucoside 8-C-arabinoside Chrysin-6-C-arabinosyl-8-C-glucoside and chrysin-6-C-glucosyl-8-C-arabinoside are α-glucosidase inhibitors, α-glucosidase inhibitors are widely used in the treatment of type 2 diabetes.
CFN92286	11-Hydroxy-12-methoxyabietatriene 11-Hydroxy-12-methoxyabietatriene is a natural product from Salvia candidissima.
CFN92287	(-)-Pinoresinol Pinoresinol is the precursor of other dietary lignans that are present in whole-grain cereals, legumes, fruits, and other vegetables, PIN can cause an upregulation of the CDK inhibitor p21(WAF1/Cip1) both at mRNA and protein levels; PIN can ameliorate CCl4-induced acute liver injury, and this protection is likely due to anti-oxidative activity and down-regulation of inflammatory mediators through inhibition of NF-kappaB and AP-1. (+)-Pinoresinol possesses fungicidal activities and therapeutic potential as an antifungal agent for the treatment of fungal infectious diseases in humans.
CFN92288	(+)-Epipinoresinol Reference standards.
CFN92289	Licoflavone C Licoflavone C has cytotoxic, and antioxidative effects, it has protective effect toward the chromosome damage induced by DAU or MMC in cultured human peripheral lymphocytes. Licoflavone C exhibits a dose-dependent antagonistic activity at concentrations up to 10−4 M, but stimulates β-galactosidase expression at higher concentrations resulting in a U-shaped-like dose-response curve.
CFN92290	Ganoderic acid C6 Ganoderic acid C6 has antinociceptive activity.
CFN92291	Methyl ganoderate H Reference standards.
CFN92292	Methyl ganoderate C6 Reference standards.
CFN92293	Chebulic acid Chebulic acid has effects against the progression of AGE-induced endothelial cell dysfunction, may constitute a promising intervention agent against diabetic vascular complications; it at both doses (25 and 50 mg/kg) improves biochemical alterations caused by renal ischemia in diabetic rats. Chebulic acid significantly reduced the tert-butyl hydroperoxide (t-BHP)-induced cell cytotoxicity, intracellular reactive oxygen species level, and the ratio of GSSH, oxidized form of glutathione (GSH) to the over total GSH (GSH + GSSG) (4.42%) as compared to that with t-BHP alone (8.33%).
CFN92294	Chebulanin Chebulanin is a topoisomerase I inhibitor, it inhibits the calcineurin pathway in C. neoformans. Chebulanin exhibits potent antifungal activity against various human pathogenic fungi with minimum inhibitory concentrations ranging from 0.25 to over 64 μg/ml. Chebulanin shows strong radical scavenging activity, good potency to chelate Fe2⁺ and good inhibition ability of lipid peroxidation. Chebulanin is a strong therapeutic alternative for the treatment of rheumatism arthritis, it suppresses the expression of inflammatory mediators and prevents cartilage destruction and bone erosion in mice.Chebulanin has anti-cancer acrtivity, it has apparent capacities of inhibiting the survival of MCF-7 human cancer cell line.
CFN92295	Chebulagic acid Chebulagic acid is a potent DNA topoisomerase inhibitor, and is also COX-2 and 5-LOX dual inhibitor. Chebulagic acid may be of value as broad-spectrum antivirals for limiting emerging/ recurring viruses known to engage host cell glycosaminoglycans for entry. Chebulagic acid can be used to control blood glucose and manage type 2 diabetes, although clinical trials are needed.
CFN92296	Chebulinic acid Chebulinic acid is a potent natural inhibitor of M. tuberculosis DNA gyrase, also can inhibit SMAD-3 phosphorylation, inhibit H+ K+-ATPase activity; it also is a natural inhibitor of vascular endothelial growth factor-A mediated angiogenesis. Chebulinic acid has hypotensive, antioxidant, anti-HIV, and anti-ulcer activities. Chebulinic acid has inhibitory effect on erythroid differentiation likely through changing transcriptional activation of differentiation relative genes, it or other tannins might influence the efficiency of some anti-tumor drugs-induced differentiation or the hematopoiesis processes.
CFN92297	Terchebulin Terchebulin has potentiality as an anti-acne agent, it shows good antibacterial activity against Propionibacterium acnes, minimum inhibitory concentration (MIC) = 125 ug/ml and minimum bactericidal concentration (MBC) = 250 ug/ml.Terchebulin, flavogallonic acid and punicalagin have antiplasmodial activity, the IC50s of them range between 8-21 microg/ml (8-40 microM) against Plasmodium falciparum 3D7 and K1.
CFN92298	1-Dehydro-6-gingerdione 1-Dehydro-6-gingerdione is a 5-HT1A receptor partial agonist.1-Dehydro-6-gingerdione has antioxidant and anti-inflammatory activities, it significantly suppresses the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) proteins in a concentration-dependent fashion.
CFN92299	8-Shogaol 8-Shogaol can induce apoptosis in a time- and concentration-dependent manner by reactive oxygen species production and depletion of glutathione in HL-60 cells.
CFN92300	10-Shogaol 10-Shogaol, as an antioxidant for human skin cell growth and a migration enhancer with potential to be a novel wound repair agent.8- and 10-Shogaol have similar metabolic profiles to [6]-shogaol and exhibit similar toxicity toward human colon cancer cells.
CFN92301	Methyl diacetoxy-6-gingerdiol Reference standards.
CFN92302	Febrifugine Febrifugine is an effective coccidiostat, possesses schizonticide props; it and its derivatives shows high degree of antimalarial activity but use limited by toxicity .
CFN92303	Isofebrifugine Isofebrifugine shows antimalarial activity.
CFN92304	Neoeriocitrin Neoeriocitrin has antioxidant capacity, it could rescue the inhibition effect of cell differentiation induced by PD98059 to some degree.Neoeriocitrin may be a new promising candidate drug for treatment of osteoporosis.
CFN92305	Momordicoside K Momordicoside K has antidiabetic activity.
CFN92306	Momordicoside F1 Momordicoside F1 may have antiproliferative activities against MCF-7, WiDr, HEp-2, and Doay human tumor cell lines.
CFN92307	Momordicoside L Momordicoside L has hypoglycaemic / antihyperglycaemic activities.
CFN92308	Momordicoside P Reference standards.
CFN97864	Tephrosin Tephrosin has potent antitumor activity by inducing autophagy pathway, internalization and degradation of inactivated EGFR and ErbB2. It may be valuable for augmenting the therapeutic efficacy of 2-Deoxy-D-glucose(DG), DG is currently under clinical evaluation for targeting tumor cells.
CFN92309	Kuguaglycoside C Kuguaglycoside C induces caspase-independent cell death, and is involved, at least in part, in the mechanism underlying cell necroptosis.
CFN92310	Ethyl (E)-ferulate Ethyl ferulate could be used for therapeutic purposes as a potent inducer of HO-1 for the protection of brain cells against oxidative and neurodegenerative conditions.
CFN92311	Shikokianin Shikokianin shows inhibitory effects on DU145 cells with IC(50) values 4.24 microM, and LoVo cells with IC(50) values 17.55 microM.

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