Natural Products
| Catalog No. | Information |
| CFN92116 | Triptonine B Triptonine B demonstrates potent anti-HIV activity with an EC(50) value of <0.10 microg/mL and an in vitro therapeutic index value of >1000. |
| CFN92117 | Aquifoliunine E-III Aquifoliunine E-III is a natural product from Tripterygium wilfordii Hook. f. |
| CFN92118 | Ebenifoline E-II Ebenifoline E-II is a natural product from Euonymus laxiflorus. |
| CFN92119 | Mayteine Mayteine may have gastroprotective activity. |
| CFN92120 | Wilfornine A Wilfornine A is a natural product from Schisandra sphenanthera. |
| CFN92121 | Alatamine Alatamine can markedly reduce acute myocardial ischemia (AMI)-induced cardiac injury and cardiac myocyte apoptosis, improve the expression and activity of sarcoplasmic/endoplasmic reticulum Ca(2+) ATPase (SERCA). |
| CFN92122 | 1-Acetyl-beta-carboline Combination of 1-acetyl-beta-carboline with ampicillin exhibits synergistic antibacterial activity against MRSA. |
| CFN92123 | 1-Ethoxycarbonyl-beta-carboline Reference standards. |
| CFN92124 | 1-Hydroxy-9-medroxycanthin-6-one Reference standards. |
| CFN92125 | 11-Hydroxycanthin-6-one 11-Hydroxy-canthin-6-one has antineoplastic activity. |
| CFN92126 | 9-Hydroxycanthin-6-one 9-Hydroxycanthin-6-one might be the active component that contributed to the aphrodisiac effect of E. longifolia by antagonizing the smooth muscle tone of CC as well as SV probably through interfering with Ca2+ mobilization.9-Hydroxycanthin-6-one inhibits Wnt signaling through the activation of GSK3β independent of CK1α. |
| CFN92127 | 9,10-Dimethoxycanthin-6-one 9,10-Dimethoxycanthin-6-one shows cytotoxic activity against a HT-1080 human fibrosarcoma cell line( IC50 = 5.0 microM). |
| CFN92128 | 4,9-Dimethoxycanthin-6-one 4,9-Dimethoxycanthin-6-one is a natural product from Ailanthus altissima. |
| CFN92129 | Eurycomalactone Eurycomalactone as a potent NF-κB inhibitor with the IC50 value of less than 1 uM. It shows antiplasmodial activity against Gombak A isolate. Eurycomalactone displays potent activity against all the tested cell lines [colon 26-L5 carcinoma (IC50 = 0.70 microM), B16-BL6 melanoma (IC50 = 0.59 microM), Lewis lung carcinoma (IC50 = 0.78 microM), and a human lung A549 adenocarcinoma (IC50 = 0.73 microM)]. |
| CFN92130 | Laurycolactone A Laurycolactone A is a natural product from Eurycoma longifolia Jack. |
| CFN92131 | Laurycolactone B Laurycolactone B is a natural product from Eurycoma longifolia Jack. |
| CFN92132 | Pelargonidin chloride Pelargonidin chloride shows protective effect against CTN-induced oxidative stress in HepG2 cells and up-regulated the activity of detoxification enzyme levels through Keap1/Nrf2 signaling pathway. It also has the antianaphylactic properties, which might be related to the increase of both cyclic AMP and cyclic GMP through the inhibition of phosphodiesterase. Pelargonidin chloride has strong antioxidative activity in a liposomal system and reduced the formation of malondialdehyde by UVB irradiation. |
| CFN92133 | Pelargonidin-3-O-rutinoside chloride Pelargonidin 3-Rutinoside exhibits antioxidant and anti-inflammatory properties. |
| CFN92134 | Pelargonidin-3-O-glucoside chloride Pelargonidin-3-O-glucopyranoside is the glucoside of Pelargonidin, an potential antidiabetic agent. Pelargonidin-3-O-glucopyranoside has antioxidant, anti-inflammatory, anti-estrogenic, and angiotensin-converting enzyme inhibitory activities. |
| CFN92135 | Cyanidin-3-O-rutinoside chloride Cyanidin-3-O-rutinoside chloride has antioxidant activity. It has LPO inhibition at a 0.25 μM concentration, inhibits the COX-1 enzyme by 45.2 and COX-2 by 61.5 at 5 μM. Cyanidin-3-O-rutinoside chloride improves vision in humans (for night blindness). |
| CFN92136 | Delphinidin-3-O-rutinoside chloride Delphinidin-3-O-rutinoside chloride has antioxidant activity. |
| CFN92137 | Delphinidin-3,5-O-diglucoside chloride Delphinidin-3,5-O-diglucoside chloride has antioxidant activity. |
| CFN92138 | Cyanidin-3,5-O-diglucoside chloride 1. Cyanidin-3,5-O-diglucoside chloride has antioxidant activity. 2. Cyanidin-3,5-O-diglucoside chloride is highly water-soluble and is easily degraded by hydrolysis and /or hydrogenation at temperatures >40°C. |
| CFN92139 | 8-Demethylsideroxylin 8-Demethylsideroxylin is a natural product from Eucalyptus robusta Smith. |
| CFN92140 | Dihydrocucurbitacin B Dihydrocucurbitacin B has anti-cancer activity, it reduces cell proliferation due to a decrease in the expression of cyclins, mainly cyclin-B1 and disruption of the actin cytoskeleton, arresting B16F10 cells in G2/M phase. Dihydrocucurbitacin B modifies the evolution of the clinical symptoms, reduces the swelling and bone and tissue damage along with the development of the disease, modifies the cell infiltration and the expression of both nitric oxide synthase-2 and cyclooxygenase-2. |
| CFN92141 | Cucurbitacin B 2-O-beta-D-glucoside Cucurbitacin B 2-o-β-D-glucoside has anticancer activity. |
| CFN92142 | Neoquassine Quassin, neoquassin and picrasinoside B are insecticide quassinoids. |
| CFN92143 | Methylneoquassin Reference standards. |
| CFN92144 | 1,2-Didehydrocryptotanshinone Reference standards. |
| CFN92145 | Tanshindiol A Reference standards. |
| CFN92146 | Tanshindiol B Tanshindiol B possesses a unique anti-cancer activity whose mechanism involves the inhibition of EZH2 activity and would provide chemically valuable information for designing a new class of potent EZH2 inhibitors. It also possesses the anti-angiogenic activity,so it can be a promising candidate for angiogenesis inhibitors. |
| CFN92147 | Tanshindiol C Tanshindiol C protects macrophages from oxLDL induced foam cell formation via activation of Prdx1/ABCA1 signaling and that Prdx1 may be a novel target for therapeutic intervention of atherosclerosis.It possesses a unique anti-cancer activity whose mechanism involves the inhibition of EZH2 activity and would provide chemically valuable information for designing a new class of potent EZH2 inhibitors. |
| CFN92148 | Methyltanshinonate Methyltanshinonate shows antiplasmodial and antitrypanosomal activities. It may have antioxidative activity. |
| CFN92149 | 6-Hydroxy-5,6-dehydrosugiol 6-Hydroxy-5,6-dehydrosugiol is a potent androgen receptor antagonist in prostate cancer cells, it has potential for use in chemoprevention and chemotherapy of prostate cancers. |
| CFN92150 | Isochamaejasmine Isochamaejasmine has inhibition of NF-kappaB activation, which could reverse the anti-apoptotic effect; it induces apoptosis in leukemia cells by inhibiting the activity of Bcl-2 family proteins, providing evidence for further studying the underlying anti-cancer mechanism of S. chamaejasme L. Isochamaejasmine shows antiplasmodial activity, with an IC(50) of 7.3+/-3.8 microM, but the selectivity was rather limited. |
| CFN92151 | Neochamaejasmine A Neochamaejasmin A can inhibit cellular (3)H-thymidine incorporation (IC 50 12.5 microg/mL) and subsequent proliferation of human prostate cancer LNCaP cells, it blocks cell cycle progression at the G1 phase by activating the p21 protein and ultimately promoting the Fas-caspase 8-caspase 3 apoptotic machinery. |
| CFN92152 | Neochamaejasmine B Neochamaejasmine B displays nematicidal activity against both Bursaphelenchus xylophilus and Bursaphelenchus mucronatus. It can reduce seedling growth and disrupt root development, the IC50 value of 6.9 ug/mL . Neochamaejasmine B has antibacterial activity on Gram-positive bacterium and Gram-negative bacterium. |
| CFN92153 | Isoneochamaejasmine A Isoneochamaejasmin A exhibits significantly nematicidal activities against both B. xylophilus and B. mucronatus. |
| CFN92154 | Chamaejasmine Chamaejasmine could be a candidate drug for osteosarcoma and breast cancer chemoprevention, induces apoptosis in MG63 and HEp-2 cells by Akt inactivation and dephosphorylation of BAD. It inhibits Bcl-2 expression and induces Bax expression to desintegrate the outer mitochondrial membrane and causes cytochrome c release. |
| CFN92155 | Sikokianin A Sikokianin A shows in vitro antiviral activity against HBsAg secretion. |
| CFN92156 | 7-Methoxyneochamaejasmine A 7-Methoxyneochamaejasmine A has a strong inhibitory effect on Festuca rubra L. and Medicago sativa seedlings. |
| CFN92157 | 8-Oxyberberine Reference standards. |
| CFN92158 | 8-Oxycoptisine Reference standards. |
| CFN92159 | 8-Oxypalmatine Reference standards. |
| CFN92160 | Neocryptotanshinone II Neocryptotanshinone inhibits lipopolysaccharide-induced inflammation in RAW264.7 macrophages by suppression of NF-κB and iNOS signaling pathways. |
| CFN92161 | Cryptoacetalide Cryptoacetalide is a natural product from Salvia miltiorrhiza. |
| CFN92162 | Epi-Cryptoacetalide Reference standards. |
| CFN92163 | Salviolone Salviolone exhibits cytotoxic activity against Vero cells. |
| CFN92164 | Epidanshenspiroketallactone Epidanshenspiroketallactone has antioxidant activity. |
| CFN92165 | 1,2-Didehydrotanshinone IIA 1,2-Didehydrotanshinone IIA shows inhibitory effects against acetyl- (AChE) and butyrylcholinesterase (BChE). It also possesses metal-chelation capacity. |
