Natural Products
| Catalog No. | Information |
| CFN92360 | Chrysin 6-C-glucoside Standard reference |
| CFN92361 | Baicalein 6-O-glucoside Baicalein 6-O-glucoside is a natural product from Thymus serpyllum L. |
| CFN92362 | 5-Methoxycanthin-6-one 5-Methoxycanthin-6-one displays moderate cytotoxic activity against the human prostate cancer cell PC-3 line, with IC₅₀ values ranging from 13.5-15.4 uM versus doxorubicine with IC₅₀ = 1.5 uM. It also exhibits a clear suppressive effect on the phagocytosis response upon activation with serum-opsonized zymosan in the range of IC₅₀ = 0.9-2.0 uM versus ibuprofen with IC₅₀ = 12.1 uM. |
| CFN92363 | Didymin Didymin is a citrus-derived natural compound that kills p53 wild-type as well as drug-resistant p53-mutant neuroblastoma cells in culture, it induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma. Didymin possesses antioxidant, anti-inflammation and anti-cancer properties. |
| CFN92364 | Notoginsenoside R2 Notoginsenoside R2 has neuroprotection against 6-OHDA-induced neurotoxicity, is associated with Notoginsenoside R2-mediated P90RSK and Nrf2 activation through MEK1/2-ERK1/2 pathways. |
| CFN92365 | 3beta-Hydroxylanosta-8,24-diene-21-al 3beta-Hydroxylanosta-8,24-diene-21-al may have cancer cell growth inhibitory activity against P388, HL-60, L1210 and KB cell lines. |
| CFN92366 | Trametenolic acid Trametenolic acid is a cytotoxic agent.It exhibits a mode of mixed inhibition with a K I of 0.9 μM, K IS of 0.5 μM, and an IC50 of 7.25 μM.Trametenolic acid and Betulin as a new candidate of potent tyrosinase inhibitors, can decrease tyrosinase activity and melanin content. |
| CFN92367 | Inotodiol Inotodiol shows significant anti-tumor and anti-tumor promoting activities, including human cervical cancer, it inhibits cell proliferation through apoptosis induction by activating caspase-3. Inotodiol can inhibit proliferation and induce the apoptosis of A549 cells, and its molecular mechanism may be associated with the up-regulating expression of p53 and bax proteins and down-regulating expression of Bcl-2 protein, which arrested A549 cells in S phase. |
| CFN92368 | Lanosterol Lanosterol is a key triterpenoid intermediate in the biosynthesis of Cholesterol. Lanosterol induces mild depolarization of mitochondria and promotes autophagy, it is indicative of altered Lanosterol metabolism during PD pathogenesis. 10 μM Lanosterol during IVM in medium without serum and bases on recombinant human chorionic gonadotrophin has a positive effect on maturation of prepubertal ewe oocytes. |
| CFN92369 | 5,7-Dihydroxychromone 7-rutinoside Reference standards. |
| CFN92370 | 6-Hydroxykaempferol 6-Hydroxykaempferol is a competitive inhibitor of tyrosinase compared to L-DOPA, it shows also high antioxidant activities. |
| CFN92371 | 6-Hydroxykaempferol 3,6-diglucoside 6-Hydroxykaempferol 3,6-di-O-glucoside and 6-hydroxykaempferol 3,6,7-tri-O-glucoside can inhibit platelet aggregation induced by collagen, they also show weak inhibitory effects on the adenosine 5'-diphosphate (ADP)- induced platelet aggregation. |
| CFN92372 | Kaempferol 3-O-beta-sophoroside Kaempferol 3-O-beta-sophoroside has antibacterial and antiviral activities. |
| CFN92373 | Diacetoxy-4-gingerdiol Reference standards. |
| CFN92374 | 1-Dehydro-10-gingerdione 1-Dehydro-10-gingerdione has anti-inflammatory action, the molecular target is Myeloid differentiation protein; it involves in the suppression of NF-κB-regulated gene expression in LPS-activated macrophages, has therapeutic potential in NF-κB-associated inflammation and autoimmune disorders. |
| CFN92375 | Diacetoxy-6-gingerdiol Reference standards. |
| CFN92376 | Butyrospermol Butyrospermol acetate exhibits inhibitory effect on skin tumor promotion in an in vivo two-stage carcinogenesis test using 7,12-dimethylbenz [a] anthracene (DMBA) as an initiator and TPA as a promoter, the exceptionally high levels of triterpenes in shea fat, indicates that shea nuts and shea fat (shea butter) constitute a significant source of anti-inflammatory and anti-tumor promoting compounds. |
| CFN92377 | alpha-Amyrin Alpha-Amyrin is trypsin and chymotrypsin inhibitor,it has antineoplastic,it induces proliferation of human keratinocytes.Alpha-Amyrin can as a hepatomodulatory potent to feasibility for a promising liver curative drug. |
| CFN92378 | Cucurbitadienol Cucurbitadienol has significant anti-inflammatory, anti-tumor effect, is also CucurbitacinBE compounds biosynthesis the key intermediate. Cucurbitadienol synthase, the first committed enzyme for cucurbitacin biosynthesis, is a distinct enzyme from cycloartenol synthase for phytosterol biosynthesis. CYP87D18 catalyzed the oxidation of cucurbitadienol at C-11 to produce 11-oxo cucurbitadienol and 11-hydroxy cucurbitadienol. |
| CFN92379 | 25-O-ethylcimigenol-3-O-beta-D-xylopyranoside 25-O-ethylcimigenol-3-O-beta-D-xylopyranoside has notable cytotoxicity against HepG2 and MCF-7 cancer cell lines. |
| CFN92380 | 25-O-methylcimigenol-3-O-beta-D-xylopyranoside 25-O-methylcimigenol-3-O-beta-D-xylopyranoside is a natural product from Actaea asiatica. |
| CFN92381 | 7,8-Didehydrocimigenol 7,8-Didehydrocimigenol can be used for the treatment of cardiovascular disorders such as atherosclerosis. It upregulates PPAR-γ in EC inhibits NF-kB activity of TNF-α-activated EC which leads to selective inhibition of VCAM-1 expression. |
| CFN92382 | 8-Methoxykaempferol Standard reference |
| CFN92383 | Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside (Astragalin 6''-O-gallate) Kaempferol 3-O-(6''-galloyl)-beta-D-glucopyranoside is an α-glucosidase inhibitor with IC50 values between 0.6 and 22.4 μM. |
| CFN92384 | Kaempferol 3-gentiobioside Kaempferol 3-O-gentiobioside has antiinflammatory activity, shows weak inhibitory effects on Concanavalin A-induced histamine release, 5-lipoxygenase, and COX-1. |
| CFN92385 | Limocitrin Limocitrin is a constituent of citrus fruit peels, belongs to the family of Flavonols. |
| CFN92386 | Kaempferol-3-O-(2',6'-di-O-trans-p-coumaroyl)-beta-D-glucopyranoside Reference standards. |
| CFN92387 | cis-Miyabenol C cis-Miyabenol C exhibits antioxidative activities and shows strong hyaluronidase inhibitory effects. cis-Miyabenol C also has ecdysteroid antagonist activity. |
| CFN92388 | Kushenol E Kushenol E exhibits significant antioxidant potentials in the ABTS, ONOO(-), and total ROS assays. |
| CFN92389 | 7,3'-Dihydroxy-5'-methoxyisoflavone 7,3'-Dihydroxy-5'-methoxyisoflavone shows moderate activity against the renal, melanoma and breast cancer cell lines, it may have a synergistic effect with other anticancer drugs. |
| CFN92390 | Kushenol X Kushenol X exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2). |
| CFN92391 | Kushenol C Kushenol C is a good 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenger, and it exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2). Kushenol C shows antimicrobial activity against Staphylococcus aureus and Streptococcus mutans. Kushenol C may be potent preventive and therapeutic candidates for Alzheimer's disease, it (IC(50) 5.45 microM) can inhibit beta-site APP cleaving enzyme 1 (BACE1) activities. |
| CFN92392 | 4-O-Feruloylquinic acid 4-O-Feruloylquinic acid can be useful for the prevention of cardiovascular and other chronic diseases. |
| CFN92393 | 3-O-Feruloylquinic acid 3-O-Feruloylquinic acid is a protease inhibitor, it exerts moderate inhibitory effect against AIV (H5N1) in vitro. |
| CFN92394 | Trans-Ferulic acid Trans-Ferulic acid has antioxidant activity, it dose-dependently reduces lipid peroxidation induced by the three oxidants; it exerts a protective action on liver injury induced by chronic ethanol ingestion. |
| CFN92395 | 13-Hydroxyoxyberberine Reference standards. |
| CFN92396 | 3,4-Dihydro-6,7-(methylenedioxy)-2(1H)-quinolinone Reference standards. |
| CFN92397 | 1,3,5-Trihydroxy-4-(3-hydroxy-3-methylbutyl)xanthone 1,3,5-Trihydroxy-4-(3-hydroxy-3-methylbutyl)xanthone is a natural product from Cudrania cochinchinensis. |
| CFN92398 | Gentisein Standard reference |
| CFN92399 | 1,3,5-Trihydroxyxanthone 1,3,5-Trihydroxyxanthone has selective inhibitory activity on platelet aggregation induced by adenosine diphosphate. |
| CFN92400 | 2,4'-Dihydroxybenzophenone Reference standards. |
| CFN92401 | 11-Deoxyalisol B Reference standards. |
| CFN92402 | Alisol F Alisol F shows anti-inflammatory activities and liver protectionthrough the inhibition of MAPK, STAT3, and NF-κB activation in vitro and in vivo, it suppresses iNOS induction. Alisol F exhibits inhibitory activity in vitro on hepatitis B virus (HBV) surface antigen (HBsAg) secretion of the Hep G2.2.15 cell line with the IC (50) value of 0.6 microM, and on HBV e antigen (HBeAg) secretion with the IC (50) value of 8.5 microM. |
| CFN92403 | 25-Anhydroalisol F 25-Anhydroalisol F shows anti-inflammatory activities and liver protection through the inhibition of MAPK, STAT3, and NF-κB activation in vitro and in vivo. It exhibits inhibitory effects on lipopolysaccharide-induced NO production in RAW 264.7 macrophage cells. |
| CFN92404 | Alisol O Standard reference |
| CFN92405 | Alisol K 23-acetate Alisol K 23-acetate is a natural product from Alisma plantago-aquatica Linn. |
| CFN92406 | Alisol B Alisol B, a novel inhibitor of the sarcoplasmic/endoplasmic reticulum Ca(2+) ATPase pump, induces autophagy, endoplasmic reticulum stress, and apoptosis.Alisol B may be a potential novel therapeutic molecule for bone disorders through targeting the differentiation of osteoclasts as well as their functions. Alisol B also inhibited RANKL-induced expression of NFATc1 and c-Fos, which are key transcription factors for osteoclastogenesis. |
| CFN92407 | 24-Deacetylalisol O 24-Deacetylalisol O is a natural product from Alisma plantago-aquatica Linn. |
| CFN92408 | Corydamine Standard reference |
| CFN92409 | Norjuziphine Norjuziphine has antiplatelet aggregation activity. |
