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Natural Products
Catalog No. Information
CFN92069 Phyltetralin

Phyltetralin has antihyperuricemic activity.
CFN92070 Isolintetralin

CFN92071 Neoschaftoside

Neoschaftoside has antioxidant activity.
CFN92072 Vitexin -4''-O-glucoside

Vitexin-4''-O-glucoside could effectively protect ECV-304 cells against cytotoxicity induced by TBHP through resuming mitochondrial function.
CFN92073 Kuguacin J

Kuguacin J is a promising candidate new antineoplastic and chemopreventive agent for androgen-dependent prostate cancer and carcinogenesis, it exerts growth inhibition through G1 arrest and induction of apoptosis in androgen-dependent human prostate cancer. Kuguacin J modulates the function of P-glycoprotein (P-gp) by directly interacting at the drug-substrate-binding site, and it appears to be an effective inhibitor of P-gp activity in vitro and thus could be developed as an effective chemosensitizer to treat multidrug-resistant cancers.
CFN92074 Kuguacin N

Kuguacin N has antioxidant activity.
CFN92075 Kuguacin R

Kuguacin R is a natural product from Momordica charantia.
CFN92076 Momordicine I

Momordicine I has anti-diabetic and antifeedant activities.
CFN92077 Sagittatoside C

Reference standards.
CFN92078 5-Galloylquinic acid

5-Galloylquinic acid as an index for the baking intensity of oolong teas. It has antioxidant activity.
CFN92079 Kaempferol-3-O-galactoside

Kaempferol-3-O-β-d-galactoside has antioxidant, anti-inflammatory and antinociceptive activities.
CFN92080 (-)-Epicatechin-3-(3''-O-methyl) gallate

(-)-Epicatechin-3-(3''-O-methyl) gallate is a natural product from Acacia catechu (L.F.) Willd.
CFN92081 (-)-Epigallocatechin-3-(3''-O-methyl) gallate

(-)-Epigallocatechin-3-(3''-O-methyl)gallate shows antioxidative, cytotoxic, antiallergic, and anti-inflammatory activities, it can negatively regulate basophil activation through the suppression of FcepsilonRI expression. Epigallocatechin-3-(3''-O-methyl)gallate has the function for cold preservation of primary rat hepatocytes.
CFN90495 Phellopterin

Phellopterin is a partial agonist of the central benzodiazepine receptors in vitro; it shows cytotoxic effect on RAW264.7 cell at the concentration from 40 to 400 μM. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium.
CFN92082 2-Picenecarboxylic acid

Reference standards.
CFN92083 Wilforol A

Wilforol A is a natural product from Tripterygium wilfordii Hook. f.
CFN92084 Zeylasteral

Zeylasteral and demethylZeylasteral are 6-oxophenolic triterpenoids isolated from the root of Maytenus blepharodes. Zeylasteral and demethylZeylasteral have antimicrobial activity against Gram-positive bacteria and the yeast Candida albicans.
CFN92085 Quercetin 3-O-[2-O-(6-O-E-feruloyl)-beta-D-glucopyranosyl]-beta-D-galactopyranoside

Quercetin 3-O-[2-O-(6-O-E-feruloyl)-beta-D-glucopyranosyl]-beta-D-galactopyranoside exhibits significant neuroprotective activity in primary cultures of rat cortical cells damaged by L-glutamate.
CFN92086 Isogambogenin

Isogambogenin is a novel cytotoxic xanthone.
CFN92087 Deoxymorellin

Reference standards.
CFN92088 Desoxygambogenin

Desoxygambogenin is a cytotoxic xanthone, it has anti-HIV-1 activity.
CFN92089 Gambogin

Gambogin is a cytotoxic xanthone.
CFN92090 Toxyloxanthone D

Reference standards.
CFN92091 Gaudichaudic acid

Gaudichaudic acid shows cytotoxicity against human leukemia K562 (K562/S) and doxorubicin-resistant K562 (K562/R) cell lines, and shows similar inhibitory effects on both cell lines.
CFN92092 2alpha-hydroxy-3beta-acetyloxy-betulic acid

Reference standards.
CFN92093 Morellic acid

Morellic acid has anti-cancer activity, it strongly inhibited the migration of HUVEC at a low concentration of 0.5 μM in HUVEC cell migration assay in vitro. Morellic acid also has antiangiogenic activity.
CFN92094 Isomorellic acid

Isomorellic acid is a cytotoxic caged xanthone.
CFN92095 Isomorellinol

Isomorellinol induces apoptosis in cholangiocarcinoma (CCA)cells which is mediated through a mitochondria-dependent signaling pathway.
CFN92096 Isogambogenic acid

Isogambogenic acid inhibits angiogenesis and may be a viable drug candidate in anti-angiogenesis therapy. Isogambogenic acid exhibits an anticancer effect by inducing autophagy-dependent cell death in NSCLC cells, which may be an effective chemotherapeutic agent that can be used against NSCLC in a clinical setting.
CFN92097 Gambogenic acid

Gambogenic acid is an inhibitor of the FGFR signaling pathway in erlotinib-resistant non-small-cell lung cancer (NSCLC) and exhibits anti-tumor effects, it can cause aberrant autophagy to induce cell death and may suggest the potential application of Gambogenic acid as a tool or viable drug in anticancer therapies.Gambogenic acid could inhibit the proliferation of melanoma B16 cells and induce their apoptosis within certain time and concentration ranges. Its mechanism in inducing the cell apoptosis may be related to PI3K/Akt/mTOR signaling pathways.
CFN92098 Epigambogic acid

Isogambogic acid shows cytotoxic activiity against KB and drug-resistant KB-V1 cell lines.
CFN92099 9R-10alpha-Hydroxyepigambogic acid

CFN92100 10alpha-Hydroxyepigambogic acid

Reference standards.
CFN92101 30-Hydroxygambogic acid

30-Hydroxygambogic acid exhibits significant cytotoxicities against the human leukemia K562/S and the corresponding doxorubicin-resistant K562/R cell lines.
CFN92102 Evonimine

Reference standards.
CFN92103 Wilfordine

Wilfordine is an insecticidally active alkaloid, Na+-K+-ATPase may be an acting target of wilfordine against some larvae of insect.
CFN92104 Peritassine A

Peritassine A is a natural product from Tripterygium wilfordii Hook. f.
CFN92105 Wilfortrine

Wilfortrine can induce liver cancer cell HepG2 apoptosis, but with no effect on the cell cycle, mainly by promoting Bax expression and inhibiting anti-apoptotic protein Bcl-2 expression. The combined treatment using wilfortrine and paclitaxel can inhibit proliferation and invasion of liver cancer cells via down-regulating Bcl-2 and up-regulating Bax, with better efficacy than single use of either drug. Wilfortrine and euonine (40.80 mg/(kg.d) x 4d ip) show marked depressant effects on humoral mediated immunity using the hemolysin reaction as indices.
CFN92106 Hypoglaunine A

Hypoglaunine A is a natural product from Tripterygium hypoglaucum.
CFN92107 Evonine

Evonine shows insecticidal activity against Mythimna separata, the LC50 value of 23.23 mg /mL.
CFN92108 Asperulosidic acid

Asperulosidic acid has been recently used in chinese medicine as a useful drug against some tumors. It has anticlastogenic activity, since the anticlastogenic irridoids have an alpha-unsaturated carbonyl group, this structure is considered to play an important role in the anticlastogenicity. Asperulosidic acid can inhibit the seed germination and growth of seedlings of large crabgrass. Asperulosidic acid, and 6-O-(beta-D-glucopyranosyl)-1-O-octanoyl-beta-D-glucopyranose are effective in suppressing 12-O-tedtradecanoylphorbol-13-acetate (TPA)- or epidermal growth factor (EGF)-induced cell transformation and associated AP-1 activity.
CFN92109 Digitolutein

Digitolutein has inhibition on the growth of Plasmodium falciparum in vitro.
CFN92110 2-(Hydroxymethyl)anthraquinone

2-(Hydroxymethyl)anthraquinone exhibits strong activity against Helicobacter pylori ATCC 43504 at 0.01 mg/disc.
CFN92111 2-Hydroxy-1-methoxyanthraquinone

2-Hydroxy-1-methoxy- anthraquinone has antiosteoporotic activity, it can promote osteoblast proliferation, and can inhibit osteoclast TRAP activity and bone resorption.
CFN92112 2-Hydroxy-3-(hydroxymethyl)anthraquinone

2-Hydroxy-3-(hydroxymethyl)anthraquinone exhibits quinone reductase (QR)- inducing activity in Hepa lclc7 cells, with the concentration required to double QR activity of 0.94 microM.
CFN92113 6-O-benzoylgomisin O

6-O-benzoylgomisin O is a natural product from Schisandra sphenanthera.
CFN92114 Interiotherin A

Interiotherin A inhibits HIV replication with the EC50 value of 3.1 micrograms/mL.
CFN90496 Decursinol

Decursinol may be a beneficial antimetastatic agent, targeting MMPs and its upstream signaling molecules; it inhibits the proliferation and invasion of CT-26 colon carcinoma cells, might via downregulated ERK and JNK phosphorylation. Aspirin-decursinol has neuroprotective effects, may be closely related to the attenuation of ischemia-induced gliosis and maintenance of antioxidants.
CFN90497 Juglone

Juglone has anti-inflammatory, and anti-cancer activities, it can significantly inhibit the proliferation and induce the apoptosis of SiHa cells and Caski cells; it prevents high-fat diet-induced liver injury and nerve inflammation in mice through inhibition of inflammatory cytokine secretion, NF-kappa B activation and endotoxin production. Juglone stimulates suicidal erythrocyte death or eryptosis at least in part by upregulation of ceramide abundance, energy depletion and activation of PKC.
CFN92115 Regelidine

Regelidine is a natural product from Tripterygium regelii.