Natural Products
| Catalog No. | Information |
| CFN98831 | Dihydrooxoepistephamiersine Reference standards. |
| CFN98832 | 2'-O-Methylisoliquiritigenin 2'-O-Methylisoliquiritigenin, a compound synthesized by enzymes specifically induced in NR. |
| CFN98833 | 7-O-Methyleriodictyol 7-O-Methyleriodictyol inhibits the maximum contractions induced by acetylcholine or oxytocin. |
| CFN98834 | Emodin Emodin has neuroprotective and antidepressant activity, can up-regulate GR and BDNF levels in hippocampus; it also has significant anti-neoplastic activity against bladder cancer cells and myeloid leukemia, by suppressing tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), iNOS and COX-2 expression. Emodin has protective effects, may be related to the inhibition of CCL5 expression and subsequent cell stress/inflammatory events possibly mediated by activation of MAPK signaling pathways. |
| CFN98835 | Matrine Matrine, a novel autophagy inhibitor, possesses anti-inflammation, immunosuppression, anti-fibrotic and anticancer activities, it could inhibit cell proliferation and induce apoptosis of SGC-7901 cells in vitro by up-regulating Fas/FasL expression and activating caspase-3 enzyme. Matrine can be a potential candidate to fight against Candida-related infections by regulating yeast-to-hypha transition. |
| CFN98836 | Maclurin Maclurin can effectively protect against mesenchymal stem cells (MSCs) oxidative damage induced by hydroxyl radical (OH) at 62.1-310.5 uM, the protective and antioxidant effects of maclurin can be primarily attributed to ortho-dihydroxyl groups, and ultimately to the relative stability of the ortho-benzoquinone form.Maclurin has anti-metastatic effect, the mechanism is by anti-oxidative activity and inhibition of Src/FAK-ERK-β-catenin signaling pathway. |
| CFN00021 | N-Methyltaurine The presence of N-Methyltaurine conjugated bile acids that are resistant to bacterial attack; the excreted N-Methyltaurine could be utilized by other bacteria in cocultures. N-Methyltaurine conjugated bile acids are resistant to bacterial deconjugation and dehydroxylation, and such resistance to bacterial enzymes should aid in the maintenance of high concentrations of bile acids during lipid digestion. |
| CFN00022 | 2-(Dimethylamino)ethanesulfonic acid Reference standards. |
| CFN00023 | N-Glyceryltaurine Reference standards. |
| CFN00024 | N-(15-Methyl-9-hexadecenoyl)taurine Reference standards. |
| CFN00025 | N-(5,8,11,14-Eicosatetraenoyl)taurine Reference standards. |
| CFN00026 | 2-Aminoethanol 2-Aminoethanol (ethanolamine) can inhibit the GABA degrading enzyme GABA aminotransferase (GABA-T), it is a possible neuromodulator in the pigeon optic tectum. Strengthening of the antioxidant mechanisms by plant pretreatment with 2-aminoethanol could be helpful in the development of a broad tolerance to adverse stress conditions. |
| CFN00027 | O-Acetylethanolamine Reference standards. |
| CFN00028 | 2-Methylaminoethanol Reference standards. |
| CFN00029 | O-Phosphorylethanolamine O-Phosphorylethanolamine coupled with aminosilanized nanodiamonds show a homogeneous interaction with the titanium substrate. |
| CFN00030 | 2-Acetamidoethyl phosphate Reference standards. |
| CFN98837 | Dehydroespeletone Standard reference |
| CFN98838 | Kaempferol 1. Kaempferol activates LXR-β and suppresses SREBP-1 to enhance symptoms in metabolic syndrome. 2. Kaempferol exerts a potent inhibitory effect on in vitro bone resorption. 3. Kaempferol has anti-inflammatory action, can prevent and treat inflammatory diseases such as rheumatoid arthritis, systemic lupus erythematosus, and ankylosing spondylitis. 4. Kaempferol has therapeutic potential for the prevention and treatment of thrombovascular diseases, can enhance relaxations caused by endothelium-derived and exogenous NO as well as those due to endothelium-dependent hyperpolarization. 5. Kaempferol can inhibit cancer cell invasion through blocking the PKCδ/MAPK/AP-1 cascade and subsequent MMP-9 expression and its activity, may act as a therapeutic potential candidate for cancer metastasis. 6. Kaempferol is an autophagic enhancer, has a more general protection in Parkinson's disease, can mediate antiapoptotic and antioxidant effects is the enhancement of mitochondrial turnover by autophagy. |
| CFN98839 | Hesperidin Hesperidin has antioxidative, anti-inflammatory, vasoprotective,and anticarcinogenic effects, it induces apoptosis and triggers autophagic markers through inhibition of Aurora-A mediated phosphoinositide-3-kinase/Akt/mammalian target of rapamycin and glycogen synthase kinase-3 beta signalling cascades in experimental colon carcinogenesis. Hesperidin also exerts its protective effect against CYP-induced hepatotoxicity through upregulation of hepatic PPARγ expression and abrogation of inflammation and oxidative stress. |
| CFN98840 | Tectochrysin Tectochrysin is a promising inhibitor for the reversal of ABCG2-mediated drug transport, it leads to apoptotic cell death in NSCLC cells through activation of DR3 and Fas expression via inhibition of STAT3 phosphorylation.Tectochrysin has antioxidant effect, it also exhibits a significant hepatoprotective activity in hepatic damage induced by CCl4-intoxication in rats. |
| CFN98841 | Tricin Tricin is evaluated as a type of tyrosinase inhibitor, it exerts anti-inflammatory effect via a mechanism involving the TLR4/NF-κB/STAT signaling cascade, tricin derivatives conveys allergy and inflammation treatment ability to Z. latifolia.Tricin is a novel compound with potential anti-HCMV activity and that CXCL11 is one of the chemokines involved in HCMV replication, it may be beneficial in HSC-targeting therapeutic or chemopreventive applications for hepatic fibrosis. |
| CFN98842 | Hesperetin Hesperetin has antioxidative and anti-inflammatory effects, it inhibits vascular formation by endothelial cells via the inhibition of the PI3K/AKT, ERK and p38 MAPK signaling. Hesperetin-mediated apoptosis of MCF-7 cells involves accumulation of ROS and activation of ASK1/JNK pathway, it induces apoptosis in triple negative breast cancer MDA-MB-231 cells via intrinsic pathway via activation of caspase -9 and -3 and increase in Bax:Bcl-2 ratio. |
| CFN98843 | Apigenin Apigenin is a potent inhibitor of CYP2C9, which has anti-inflammatory, antiangiogenic, and anti-cancer effects, it may inhibit EV71 replication through suppressing viral IRES activity and modulating cellular JNK pathway. |
| CFN98844 | 2-Hydroxy-7-O-methylscillascillin |
| CFN98845 | 3-O-Acetylpinobanksin 3-O-Acetylpinobanksin may have anti-inflammatory and analgesic activies. |
| CFN98846 | Bilobetin Bilobetin treatment ameliorates hyperlipidaemia, lipotoxicity and insulin resistance in rats by stimulating PPARα-mediated lipid catabolism. |
| CFN00031 | (2-Aminoethyl)phosphinic acid The specific growth rates of C. raciborskii cells in media treated with β-glycerol phosphate, d-glucose-6-phosphate, and (2-aminoethyl)phosphinic acid are significantly higher than those of cells grown in phosphorus free media. |
| CFN00032 | (2-Aminoethyl)phosphonic acid 2-Aminoethylphosphonic acid as an indicator of Tetrahymena pyriformis W growth in protein-quality evaluation assay. |
| CFN00033 | 2-(Methylamino)ethylphosphonic acid Reference standards. |
| CFN00034 | 2-Dimethylaminoethylphosphonic acid Reference standards. |
| CFN00035 | (2S,3R,4E)-2-Amino-4-heptadecene-1,3-diol Reference standards. |
| CFN00036 | Obscuraminol B Reference standards. |
| CFN00037 | Obscuraminol C Reference standards. |
| CFN00038 | Obscuraminol F Reference standards. |
| CFN00039 | Obscuraminol E Reference standards. |
| CFN00040 | Obscuraminol D |
| CFN00041 | Zooxanthellabetaine A Reference standards. |
| CFN00042 | Streptenol E Reference standards. |
| CFN00043 | (2-Amino-1-hydroxyethyl)phosphonic acid Reference standards. |
| CFN00044 | 1-Deoxydihydroceramide-1-sulfonic acid Reference standards. |
| CFN00045 | 4-Amino-4-methyl-2-pentanone Reference standards. |
| CFN98847 | Sciadopitysin Sciadopitysin shows protective effects on antimycin A-induced toxicity in osteoblastic MC3T3-E1 cells, it may reduce or prevent osteoblasts degeneration; it also may prevent the development of diabetic osteopathy, it exerts its therapeutic effects via upregulation of mitochondrial biogenesis. Sciadopitysin can inhibit the Aβ aggregation and reduce Aβ-induced toxicity in the primary cortical neurons. |
| CFN98848 | Physcion Physcion shows cytotoxic effect on human cervical carcinoma HeLa cells and its apoptosis induction in HeLa cells was investigated by the expressions of p53, p21, Bax, Bcl-2, caspase-9, and caspase-3 proteins. Physcion controls powdery mildew mainly through changing the expression of defence-related genes, and especially enhancing expression of leaf-specific thionin in barley leaves. |
| CFN98849 | Evoxine Evoxine is a small molecule that counteracts CO2-Induced immune suppression, it can counteract the CO2-induced transcriptional suppression of antimicrobial peptides in S2* cells. Evoxine and arborinine display moderate antiplasmodial activity against the CQS D10 strain of Plasmodium falciparum, with IC(50) values of 24.5 and 12.3 microM, respectively. |
| CFN98850 | Quercitrin Quercitrin is an antibacterial agent and inhibits the oxidation of low-density lipoproteins and prevent an allergic reaction; quercitrin and DNJ in combination as a potent anticariogenic agent against S. mutans.Quercitrin has antioxidant, anti-inflammatory, anti-cancer, and anti-allergic activities. Quercitrin has antiproliferative and apoptotic effects on lung cancer cells and colon cancer cells by modulating the immune response; it promotes osteoblast differentiation in MC3T3-E1 cells and also inhibit osteoclastogenesis in RAW264.7 cells. |
| CFN98851 | 3-Epicorosolic acid 3-Epicorosolic acid has a potent inhibitory effect on Epstein-Barr virus early antigen (EBV-EA) induction, it has potential anti-inflammatory activities as well as cancer chemopreventive activity.3-Epicorosolic acid shows both potent α-glucosidase and protein tyrosine phosphatase 1B (PTP1B) inhibitory activities with IC50 values of 30.18 and 4.08 μg/ml respectively. |
| CFN98852 | Lochnerine Lochnerine shows potent vasorelaxant activity, it also shows some antitumor activity, it can bring about complete inhibition of cell growth in P388 leukemia cells in vitro. |
| CFN98853 | Vindorosine Vindorosine has blood vessel relaxation effect, possible underlying mechanisms involving the inhibition of Ca(2+) entry via L-type Ca(2+) channels in vascular smooth muscles. |
| CFN98854 | Angelicin Angelicin has anti-cancer, antiviral, and anti-inflammatory activities; it regulates LPS-induced inflammation via inhibiting MAPK/NF-κB pathways. Angelicin is a powerful inducer of erythroid differentiation and -globin mRNA accumulation of human leukemia K562 cells, it is a potential therapeutic approach in hematological disorders, including -beta-thalassemia and sickle cell anemia. |
| CFN98855 | Erysotramidine (+)-Erysotramidine shows potent dosedependant antifeedant activity at concentrations 3100 ppm. |
