Natural Products
| Catalog No. | Information |
| CFN98594 | Cyasterone Cyasterone, a natural EGFR inhibitor, can inhibit growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it maybe a promising anti-cancer agent; it also has antifeeding activity. |
| CFN98595 | Methylophiopogonanone A Methylophiopogonanone A has anti-inflammatory and anti-oxidative properties, it also has therapeutic potential against cerebral I/R injury through its ability to attenuate BBB disruption by regulating the expression of MMP-9 and tight junction proteins. |
| CFN98596 | Methylophiopogonanone B Methylophiopogonanone B has inhibition of hypoxia-inducible factor (HIF)-1 alpha activity.Methylophiopogonanone B can inhibit melanosome transfer to keratinocytes as well as melanocyte dendrite outgrowth, it also suppress pigmentation in a three-dimensional skin culture model through the inhibition of melanocyte dendrite outgrowth, it could result in the creation of very unique cosmetic products that would precisely control the darkening or lightening of skin tone. |
| CFN98597 | Theaflavin Theaflavin is a suitable natural inhibitor against influenza A (H1N1) neuraminidase, which has anti-inflammatory, antioxidative, anti-mutagenic, anti-HSV-1, and anti-carcinogenic properties. Theaflavin is active in the prevention of fatty liver and obesity, it can significantly reduce lipid accumulation, suppress fatty acid synthesis, and stimulate fatty acid oxidation. Theaflavin inhibits LPS-Induced IL-6, MCP-1, and ICAM-1 expression in bone marrow-derived macrophages through the blockade of NF-κB and MAPK signaling pathways; it also protects nigral dopaminergic neurons against chronic MPTP/probenecid induced Parkinson's disease. |
| CFN98598 | Theaflavine-3,3'-digallate Theaflavin-3,3'-digallate is a potent AMP-activated protein kinase (AMPK) activator with anti-adiposity activity in adipocytes, suggesting its potential application in functional foods and nutraceuticals for obesity management. Theaflavin-3,3'-digallate is also an inducer of oxidative stress and apoptosis, it has strong antioxidant and antiangiogenic activities, it inhibits the tube formation of endothelial cells via decreased both MMP-2 and MMP-9 activities in vitro. A combination microbicide containing theaflavin-3,3'-digallate and lactic acid can reduce herpes simplex virus (HSV) transmission. Theaflavin-3,3'-digallate may exert its anti-inflammatory and cancer chemopreventive actions by suppressing the activation of NFkappaB through inhibition of IkappaB kinase (IKK) activity. Theaflavin-3,3'-digallate can repress osteoclastogenesis and prevent wear debris-induced osteolysis via suppression of ERK pathway, it is a promising candidate for the treatment of osteoclast-related osteolytic diseases, such as wear debris-induced peri-implant osteolysis (PIO). |
| CFN98599 | Theaflavin-3'-gallate Theaflavin-3'-gallate, acts as prooxidants and induces oxidative stress, with carcinoma cells more sensitive than normal fibroblasts. |
| CFN98807 | Arteannuin B Arteannuin B and artemisinic acid are biogenetic precursors of artemisinin, an important antimalarial produced by the herb Artemisia annua, they are active against different bacteria and certain fungal species. Arteannuin B has potential antimalarialand antitumor activity. |
| CFN98808 | Taiwanhomoflavone B Taiwanhomoflavone B is cytotoxic with ED(50) values of 3.8 and 3.5 microg/ml, against KB oral epidermoid carcinoma and Hepa-3B hepatoma cells, respectively. |
| CFN98809 | Verminoside Verminoside exhibits anti-inflammatory, anti-bacterial and anti-properties, it attenuates intracellular ROS and stress (oxidative and thermal) level promoting longevity, the longevity and stress modulation can be attributed to VMS-mediated alterations in daf-16 expression which regulates insulin signaling pathway. Verminoside induces genotoxicity on human lymphocytes, involved with PARP-1 and p53 proteins. |
| CFN98810 | Canadine Canadine has antioxidant activity with low-toxic effect. |
| CFN98811 | Minecoside Minecoside exhibits potent antioxidant activity. |
| CFN98812 | Echinocystic acid Echinocystic acid has cardioprotective, hypolipidemic, anti-tumor, anti-inflammatory and antioxidant effects, it displays substantial inhibitory activity on HCV entry.Orally administered lancemaside A may be metabolized to echinocystic acid, which may be absorbed into the blood and ameliorate memory and learning deficits by inhibiting AChE activity and inducing BDNF and p-CREB expressions.Orally administered lancemaside A may be metabolized to echinocystic acid, which may be absorbed into the blood and ameliorate memory and learning deficits by inhibiting AChE activity and inducing BDNF and p-CREB expressions. |
| CFN98813 | 2,7-Dihydrohomoerysotrine 2,7-Dihydrohomoerysotrine possesses cardiodepressant activities on the heart of B. glabrata. |
| CFN98814 | alpha-Onocerol Reference standards. |
| CFN98815 | Plumieride Plumieride has plant growth inhibiting properties, it shows strong fungitoxicity against some dermatophytes causing dermatomycosis to animals and human beings. Plumieride also has antioxidant , and immunomodulatory activities. |
| CFN98816 | Wighteone Wighteone is an antifungal isoflavone.Wighteone has in vitro cytocidal activity against KB cells, it has a potent anti-proliferative effect on human leukemia HL-60 cancer cell lines, it can effectively inhibit the proliferation of HER2-positive cancer cell lines, and this is considered to be the result of downregulating HSP90 receptor and downstream signaling. |
| CFN00001 | AAL Toxin TA1 AAL-toxins TA 1 and TA 2 are host-specific toxins (HST) produced by Altemaria altemata f. sp. lycopersici, a causal fungus of tomato stem canker. |
| CFN00002 | AAL Toxin TB1 AAL toxins TA and TB are phytotoxins, isolated from corn cultures by aqueous extraction. AAL-toxin is a potent natural herbicide, which disrupts sphingolipid metabolism of plants. |
| CFN00003 | AAL Toxin TD1 AAL-toxin has a wide range of phytotoxicity, it has potential as a natural herbicide because several important weeds including jimsonweed, black nightshade, prickly sida and hemp sesbania are quite sensitive, while some crops such as cotton and maize are not affected. |
| CFN00004 | AAL Toxin TC1 AAL-toxin has a wide range of phytotoxicity, it has potential as a natural herbicide because several important weeds including jimsonweed, black nightshade, prickly sida and hemp sesbania are quite sensitive, while some crops such as cotton and maize are not affected. |
| CFN00005 | AAL Toxin TE1 AAL-toxin has a wide range of phytotoxicity, it has potential as a natural herbicide because several important weeds including jimsonweed, black nightshade, prickly sida and hemp sesbania are quite sensitive, while some crops such as cotton and maize are not affected. |
| CFN00006 | AAL Toxin TA2 AAL toxins TA and TB are phytotoxins, isolated from corn cultures by aqueous extraction. AAL-toxin has a wide range of phytotoxicity, it has potential as a natural herbicide because several important weeds including jimsonweed, black nightshade, prickly sida and hemp sesbania are quite sensitive, while some crops such as cotton and maize are not affected. |
| CFN00007 | AAL Toxin TB2 AAL-toxin has a wide range of phytotoxicity, it has potential as a natural herbicide because several important weeds including jimsonweed, black nightshade, prickly sida and hemp sesbania are quite sensitive, while some crops such as cotton and maize are not affected. |
| CFN00008 | AAL Toxin TD2 AAL-toxin has a wide range of phytotoxicity, it has potential as a natural herbicide because several important weeds including jimsonweed, black nightshade, prickly sida and hemp sesbania are quite sensitive, while some crops such as cotton and maize are not affected. |
| CFN00009 | AAL Toxin TC2 AAL-toxin has a wide range of phytotoxicity, it has potential as a natural herbicide because several important weeds including jimsonweed, black nightshade, prickly sida and hemp sesbania are quite sensitive, while some crops such as cotton and maize are not affected. |
| CFN00010 | AAL Toxin TE2 AAL-toxin has a wide range of phytotoxicity, it has potential as a natural herbicide because several important weeds including jimsonweed, black nightshade, prickly sida and hemp sesbania are quite sensitive, while some crops such as cotton and maize are not affected. |
| CFN98817 | 2,6-Dimethyl-3,7-octadiene-2,6-diol Standard reference |
| CFN98818 | 5,7-Diacetoxy-3,4',8-trimethoxyflavone Reference standards. |
| CFN98819 | 7,4'-Di-O-methylapigenin Apigenin 7, 4'-dimethyl ether (7,4'-Di-O-methylapigenin) can inhibit α-glucosidase and α-amylase enzymes and enhance 2-NBDG uptake in L6 cells, it has hypolipidemic effect on mouse pre-adipocyte (3T3L1) cell lines. |
| CFN98820 | delta-Amyrin acetate β-Amyrin acetate and β-Amyrin acetate have antidyslipidemic activity. |
| CFN98821 | Taraxerone Taraxerone has allelopathic and antifungal effects.Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration with the concentration dependent manner. |
| CFN98822 | Odonicin Standard reference |
| CFN98823 | Neoechinulin A Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and p38 MAPK pathways, it may block the phosphorylation of mitogen-activated protein kinase (MAPK) molecule p38, apoptosis signal-regulating kinase 1 (ASK-1) and nuclear translocation of nuclear factor-κB (NF-κB) p65 and p50 subunits, it has a potential to be developed as a modulator of neuroinflammatory process in Alzheimer's disease. Neoechinulin A may ameliorate rotenone toxicity by activating a cytoprotective machinery that requires ATP and antioxidant/anti-nitration activities. |
| CFN98824 | Atropine Atropine is a competitive antagonist of the muscarinic acetylcholine receptors (acetylcholine being the main neurotransmitter used by the parasympathetic nervous system), used to treat certain types of nerve agent and pesticide poisonings, some types of slow heart rate, and to decrease saliva production during surgery. |
| CFN98825 | Cerevisterol Cerevisterol is a cytotoxic steroid, can inhibit the activity of DNA polymerase alpha. It can stimulate NGF-mediated neurite outgrowth on PC12 cells. |
| CFN98826 | Murrangatin diacetate Standard reference |
| CFN00011 | (2-Acetoxyethyl)trimethylammonium (2-Acetoxyethyl)trimethylammonium is a neurotransmitter, cholinergic and miotic agent.It is also a cardiac depressant, and peripheral vasodilator. |
| CFN00012 | Actinine α-Actinine promotes metastasis in gastric cancer. |
| CFN00013 | Nitrosostromelin Reference standards. |
| CFN00014 | 2'-Aminoacetophenone A new route to oxcarbazepine (Trileptal), the most widely prescribed antiepileptic drug, starting from commercially available 2'-aminoacetophenone and 1,2-dibromobenzene, is reported. |
| CFN00015 | 2-(N,N-Dimethylamino)acetophenone Reference standards. |
| CFN00016 | 2-Amino-3-(3-bromo-5-chloro-4-hydroxyphenyl)propanoic acid Reference standards. |
| CFN00017 | 2-Amino-3-dodecanol Reference standards. |
| CFN00018 | Halaminol B Reference standards. |
| CFN00019 | Hypotaurine Hypotaurine is a precursor of taurine and an antioxidant, intracellular hypotaurine is mainly supplied to placental trophoblasts by transfer from extracellular fluid across the plasma membrane, and may play a role in cell protection by scavenging reactive oxygen species. Hypotaurine also suppresses acute, inflammatory, and neuropathic pain, may regulate nociceptive transmission physiologically by activating glycinergic neurons in the spinal cord, is a promising candidate for treating various pain states.Hypotaurine/taurine synthesis strongly inhibits cysteinesulfinate decarboxylase (pyridoxal 5'-phosphate-dependent enzyme) as well as cystathionine γ-lyase. Hypotaurine and raffinose supplementation in semen extenders provide a protection of sperm parameters against cryopreservation injury. |
| CFN00020 | Taurine Taurine, a free β-amino acid with remarkable antioxidant activity, is used in Taurine-enriched beverages to boost the muscular power of athletes. Taurine can effectively promote chondrocyte growth and enhance accumulation of glycosaminoglycans and collagens in the conditioned media of chondrocytes, it is effective in proliferation promotion and phenotype maintenance of chondrocytes, thus, taurine may be a useful pro-chondrogenic agent for autologous chondrocyte implantation in the treatment of cartilage repair.Taurine also can attenuate nandrolone decanoate-induced poor sperm quality and testicular toxicity in rats. |
| CFN98827 | Erythrartine Standard reference |
| CFN98828 | Stephanine l-Stephanine is a potent and highly selective alpha 1 adrenoceptor blocker, inhibits anococcygeus muscle contraction induced by phenylephrine with pA2 values of 6.76. Stephanine shows significant antiplasmodial activities with IC(50) ranged from 1.2 uM to 52.3 uM. Stephanine and crebanine have high inhibitory activity against gram-positive animal pathogenic bacteria, with MIC values of 0.078-0.312g/l, but low inhibitory activity against gram-negative animal pathogenic bacteria, they also inhibit hyphal growth of the plant pathogens Cercospora kaki. |
| CFN98829 | Rengynic acid Rengynic acid has potent antiviral effect on RSV for the first time in vitro. |
| CFN98830 | Oxoepistephamiersine Standard reference |
