Natural Products
| Catalog No. | Information |
| CFN92098 | Epigambogic acid Isogambogic acid shows cytotoxic activiity against KB and drug-resistant KB-V1 cell lines. |
| CFN92097 | Gambogenic acid Gambogenic acid is an inhibitor of the FGFR signaling pathway in erlotinib-resistant non-small-cell lung cancer (NSCLC) and exhibits anti-tumor effects, it can cause aberrant autophagy to induce cell death and may suggest the potential application of Gambogenic acid as a tool or viable drug in anticancer therapies.Gambogenic acid could inhibit the proliferation of melanoma B16 cells and induce their apoptosis within certain time and concentration ranges. Its mechanism in inducing the cell apoptosis may be related to PI3K/Akt/mTOR signaling pathways. |
| CFN92096 | Isogambogenic acid Isogambogenic acid inhibits angiogenesis and may be a viable drug candidate in anti-angiogenesis therapy. Isogambogenic acid exhibits an anticancer effect by inducing autophagy-dependent cell death in NSCLC cells, which may be an effective chemotherapeutic agent that can be used against NSCLC in a clinical setting. |
| CFN92094 | Isomorellic acid Isomorellic acid is a cytotoxic caged xanthone. |
| CFN92093 | Morellic acid Morellic acid has anti-cancer activity, it strongly inhibited the migration of HUVEC at a low concentration of 0.5 μM in HUVEC cell migration assay in vitro. Morellic acid also has antiangiogenic activity. |
| CFN92092 | 2alpha-hydroxy-3beta-acetyloxy-betulic acid Reference standards. |
| CFN92088 | Desoxygambogenin Desoxygambogenin is a cytotoxic xanthone, it has anti-HIV-1 activity. |
| CFN90495 | Phellopterin Phellopterin is a partial agonist of the central benzodiazepine receptors in vitro; it shows cytotoxic effect on RAW264.7 cell at the concentration from 40 to 400 μM. Phellopterin reduces TNF-alpha-induced VCAM-1 expression through regulation of the Akt and PKC pathway, which contributes to inhibit the adhesion of monocytes to endothelium. |
| CFN92081 | (-)-Epigallocatechin-3-(3''-O-methyl) gallate (-)-Epigallocatechin-3-(3''-O-methyl)gallate shows antioxidative, cytotoxic, antiallergic, and anti-inflammatory activities, it can negatively regulate basophil activation through the suppression of FcepsilonRI expression. Epigallocatechin-3-(3''-O-methyl)gallate has the function for cold preservation of primary rat hepatocytes. |
| CFN92079 | Kaempferol-3-O-galactoside Kaempferol-3-O-β-d-galactoside has antioxidant, anti-inflammatory and antinociceptive activities. |
| CFN92076 | Momordicine I Momordicine I has anti-diabetic and antifeedant activities. |
| CFN92071 | Neoschaftoside Neoschaftoside has antioxidant activity. |
| CFN92065 | Iso-mogroside V Iso-mogroside V is approximately 500 times sweeter than 0.5% (w/v) sucrose. |
| CFN92060 | Syringaresinol (-)-Syringaresinol may be a potential chemotherapeutic agent for the treatment of cancer; it against H/R-induced cardiomyocyte injury and death, the degradation of HIF-1α through activation of FOXO3 is a potential therapeutic strategy for ischemia-related diseases. Syringaresinol induces vasorelaxation by enhancing NO production in endothelial cells via two distinct mechanisms, phosphatidylinositol 3-kinase/Akt- and PLC/Ca(2+)/CaMKKβ-dependent eNOS phosphorylation and Ca(2+)-dependent eNOS dimerization. |
| CFN92057 | Ganoderic acid K Ganoderic acid K is an angiotensin-converting enzyme inhibitor. It has anti-tumor, and anti-inflammatory activities. |
| CFN92056 | Ganoderic acid H Ganoderic acid H is a potent antitumour agent, it mediates its biological effects through the inhibition of transcription factors AP-1 and NF-kappaB, resulting in the down-regulation of expression of Cdk4. |
| CFN92055 | Ganoderic acid F Ganoderic acid F has anti-hepatitis B, anti-inflammatory, and anti-tumor-promoting activities. |
| CFN92054 | Ganoderic acid C2 Ganoderic acid C2 has anti-inflammatory,and anti-tumor-promoting activities. Ganoderic acid C2 can inhibit histamine release, it also has inhibitory effects on the induction of Epstein-Barr Virus early antigen. |
| CFN92052 | Ganoderic acid B Ganoderic acid B is a chemical marker in quality control of G. lucidum and related products. Ganoderic acid B-containing herbs has potential influence towards therapeutic window of trifluoperazine.Ganoderic acid B has antinociceptive effect; it is moderately active inhibitors against HIV-1 protease with a 50% inhibitory concentration of 0.17-0.23 mM. |
| CFN92051 | Ganoderic acid A Ganoderic acid A , a representative active triterpenoid from Ganoderma lucidum, exhibits antinociceptive, antioxidative, cytotoxic, hepatoprotective and anticancer activities. It has a wide spectrum of targets including nuclear transcription factor-kappaB,activator protein-1,STAT,IL-6,JAK, and p38MAPK. |
| CFN92049 | Malvidin-3-O-glucoside chloride Malvidin 3-glucoside has antioxidant activity, alone is not oxidized in the presence of grape polyphenol oxidase. Malvidin 3-glucoside's color stabilization at a higher pH can be explained by self-aggregation of the flavylium cation and copigmentation with the Z-chalcone form. |
| CFN92048 | Malvidin-3-O-galactoside chloride Malvidin-3-O-galactoside chloride has antioxidant activity. |
| CFN92047 | Peonidin-3-O-arabinoside chloride Peonidin-3-O-arabinoside chloride has antioxidant activity. |
| CFN92046 | Peonidin-3-O-glucoside chloride Peonidin-3-O-glucoside chloride has antioxidant activity, is a radical scavenger. |
| CFN92045 | Peonidin-3-O-galactoside chloride Peonidin-3-O-galactoside chloride has antioxidant activity. |
| CFN92043 | Petunidin-3-O-glucoside chloride Petunidin-3-O-glucoside chloride has significantly higher antioxidant activity than the Fe2+ control. Petunidin-3-O-glucoside causes problems in digestibility, may be important dietary supplements with beneficial health effects. |
| CFN92042 | Petunidin-3-O-galactoside chloride Petunidin-3-O-galactoside chloride has antioxidant activity. |
| CFN92041 | Cyanidin-3-O-arabinoside chloride Cyanidin-3-O-arabinoside chloride has antioxidant activity. It reduces the peroxynitrite-induced suppression of mitochondrial respiration, DNA damage, PARS activation and vascular dysfunction in HUVECs. |
| CFN92040 | Cyanidin-3-O-galactoside chloride Cyanidin-3-O-galactoside chloride has anti-obesity and hypolipidemic effects. |
| CFN92038 | Delphinidin-3-O-glucoside chloride Delphinidin-3-O-glucoside chloride has antioxidant activity. |
| CFN92037 | Delphinidin-3-O-galactoside chloride Delphinidin-3-O-galactoside chloride has anti-obesity and hypolipidemic effects. Delphinidin-3-O-galactoside (D3G) is a water-soluble anthocyanin with antioxidant activity. D3G is capable of masking the EGCG-induced cytotoxicity and ER stress, presumably through up-regulation of antioxidant enzymes and heat shock proteins. |
| CFN92032 | Vicenin -3 Tulsi and its flavonoids orientin and vicenin possess radioprotective effects. Orientin and vicenin can protect against foetal irradiation-induced genomic damage and instability, thereby reducing the delayed chromosomal abnormalities and tumorigenesis in adult. |
| CFN92031 | Vicenin -2 Vicenin -2 has hepatoprotective, anti-cancer, antioxidant and anti-inflammatory activities, and DTL co-administration is more effective than either of the single agents in androgen-independent prostate cancer. Vicenin -2 might be a useful lead for the development of multiple target-oriented therapeutic modalities for the treatment of diabetes and diabetes-associated complications. Vicenin -2 could act as a UV light barrier to protect the plants. |
| CFN92030 | Vicenin -1 Vicenin-1 possesses potent anti-inflammatory and anti-oxidant activity. |
| CFN92029 | Isoschaftoside Isoschaftoside is used as an intercrop due to its allelopathic inhibition of parasitism by Striga hermonthica, an obligate parasitic weed that can devastate the maize crop. Isoschaftoside has anti-tumor, antioxidant, and antimicrobial activities, it also possesses strong nematicidal activity against M. incognita. |
| CFN92027 | Curzerenone Curzerenone holds great promise for use in chemopreventive and chemotherapeutic strategies, it has slightly effective against E. coli (IZ = 10.8 ± 0.52). |
| CFN92026 | Curcumenone Curcumenone may have protective effect on drunkenness, through increasing liver alcohol dehydrogenase activity. |
| CFN92025 | Acetoxyisovalerylalkannin Acetoxyisovalerylalkannin may have anti-ageing activity, it can upregulate Collagen-I, elastin and involucrin syntheses in human dermal fibroblasts or keratinocytes. |
| CFN92023 | Isobutylshikonin Isobutylshikonin exhibits obvious antioxidant activities , it exerts very good radical scavenging activities toward ABTS+ but shows moderate inhibition of DPPH·. |
| CFN92016 | 8-Prenylnaringenin 8-Prenylnaringenin is a phytoestrogen with high estrogenic activity, it shows more potent effects on promoting osteoblastic bone formation and inhibiting osteoclastic bone resorption by ERα instead of ERβ than the two classic phytoestrogens: genistein and daidzein. 8-Prenylnaringenin at all assayed doses (0.001-20 µM) presumably improves mitochondrial function, whereas a high dose of XN (5 µM) worsens the functionality of this organelle. |
| CFN92008 | Eurycomanone Eurycomanone has anti-cancer activity, it is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2. |
| CFN92007 | Hinokiflavone Hinokiflavone has significant cytotoxicity, it has inhibition of MMP-9. |
| CFN92005 | Sophoraflavanone G Sophoraflavanone G has an anti-inflammatory effect, it has strong antimicrobial activity against mutans streptococci and could be useful in the development of novel oral hygiene products, such as a gargle solution or dentifrice. Sophoraflavanone G is a novel small-molecule inhibitor, it inhibits the NF-κB and MAPK signaling pathways. |
| CFN92003 | Kurarinone Kurarinone exhibits anti-tumor, estrogenic, and anti-inflammatory activities, it also shows strong inhibitory effect on immune responses. Kurarinone may ameliorate chronic inflammatory skin diseases through the suppression of pathogenic CD4(+) T-cell differentiation and the overall immune response. Kurarinone sensitizes TNF-related apoptosis inducing ligand (TRAIL)-induced tumor cell apoptosis via suppression of NF-κB-dependent cFLIP expression; it may be by way of down-regulating Smad3 expression to interfere its induction on intercellular signal transduction and consequently ameliorate renal interstitial fibrosis. |
| CFN90490 | Hosenkoside C Hosenkoside C is a natural product from Impatiens balsamina L. |
| CFN90472 | Deapi-platycodin D Deapi-platycodin D has anti-inflammatory activity, it can regulate the production and secretion of airway mucin and, at least in part, explains the traditional use of aqueous extract of APG as expectorants in diverse inflammatory pulmonary diseases. |
| CFN90470 | Rebaudioside B Rebaudioside B tastes about 150 times sweeter than sucrose and it is non-caloric. |
| CFN97852 | Andrographidine C Standard reference |
| CFN90458 | Syringaresinol-di-O-glucoside Syringaresinol-di-O-glucoside protects the animals from the stress-induced decreases in sex behaviours and in rectal temperature, the stress-induced failure of retrieval of memory, and the stress-induced enlargement of adrenal gland. |
| CFN90456 | Soyasaponin Bb Soyasaponin Bb can suppress Eca-9706 cell growth, reverse effects on over expression of c-met, VEGF, and induce cell apoptosis through inhibiting HDAC1-NF-kappaB and activating PETEN and caspase-3 signaling pathways. |
